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21. 发明授权

US5688272A Top-tightening transverse connector for a spinal fixation system 失效
标题翻译：用于脊柱固定系统的顶部紧固横向连接器
公开(公告)号：US5688272A
公开(公告)日：1997-11-18
申请号：US413387
申请日：1995-03-30
申请人： Leslie A. Montague , Michael C. Sherman , Eddie Ray, III
发明人： Leslie A. Montague , Michael C. Sherman , Eddie Ray, III
IPC分类号： A61B17/70
CPC分类号： A61B17/705 , A61B17/7052 , A61B17/7037 , A61B17/7038 , A61B17/7041
摘要： A new top-loading transverse connector of the present invention for bridging between longitudinal members of a spinal fixation system implant. The transverse connector is loaded and clamped to the longitudinal member from the top permitting easy access and adjustment and may clamp at the same location along the rod as a vertebral fixation element. The transverse connector comprises an elongate body and an engagement portion on each opposing end of the elongate body. The engagement portion includes downward legs each with a surface to engage the longitudinal member. The downward legs are displaced from each other to define a space therebetween. The engagement portion includes an upper surface defining an opening therethrough. The opening intersects the space defined between the downward legs. Together, the space and opening are configured to receive the clamp assembly carried on the longitudinal member. Another object of the invention, is to provide an improved system including the transverse connector. Another object of the invention is to provide a transverse connector that clamps to the longitudinal member at a variable angle. Another object of the invention is to provide a separate engagement portion which can be used with existing transverse connectors to permit clamping at the same site as vertebral fixation elements. Another object of the invention is to provide a way to adjust the length of the elongate body of the transverse connector.
摘要翻译：一种用于桥接脊柱固定系统植入物的纵向构件的本发明的新的顶部加载横向连接器。横向连接器从顶部装载和夹紧到纵向构件，允许容易地进入和调节，并且可以沿着杆作为椎骨固定元件夹紧在相同位置。横向连接器包括细长主体和在细长主体的每个相对端上的接合部分。接合部分包括各自具有与纵向构件接合的表面的向下的腿。向下的腿彼此移位以限定它们之间的空间。接合部分包括限定穿过其中的开口的上表面。开口与下方的腿间限定的空间相交。一起，空间和开口构造成接收承载在纵向构件上的夹具组件。本发明的另一个目的是提供一种包括横向连接器的改进的系统。本发明的另一个目的是提供一种以可变角度夹紧纵向构件的横向连接器。本发明的另一个目的是提供一种单独的接合部分，其可以与现有的横向连接器一起使用以允许在与椎骨固定元件相同的位置处夹紧。本发明的另一个目的是提供一种调节横向连接器的细长主体长度的方法。

22. 发明授权

US08663328B2 Methods for positioning a load-bearing component of an orthopedic implant device by inserting a malleable device that hardens in vivo 有权
标题翻译：通过插入在体内硬化的可延展装置来定位矫形植入装置的承重部件的方法
公开(公告)号：US08663328B2
公开(公告)日：2014-03-04
申请号：US11643177
申请日：2006-12-21
申请人： Jeff R. Justis , Dimitri Protopsaltis , Hai H. Trieu , Michael C. Sherman
发明人： Jeff R. Justis , Dimitri Protopsaltis , Hai H. Trieu , Michael C. Sherman
IPC分类号： A61F2/44
CPC分类号： A61B17/7032 , A61B17/7013 , A61B17/80 , A61B17/8085 , A61B17/866 , A61B2017/00004 , A61B2017/00831 , A61F2/441 , A61F2/442 , A61F2/4425 , A61F2/4465 , A61F2/447 , A61F2002/30062 , A61F2002/30579 , A61F2002/30583 , A61F2002/30649 , A61F2002/30841 , A61F2002/30884 , A61F2210/0004 , A61F2210/0085
摘要： A device is provided that is non-rigid, i.e., flexible and/or malleable, in a first form, and then transformable after insertion to an in vivo site into a rigid, or hardened, form; a cure-initiating energy is applied to the device; and the device is then positioned in the in vivo site where it hardens to provide a load-bearing function or other structural and/or mechanical function. The device includes a biocompatible sheath and a curable material sealed within the sheath. The curable material is provided in a first form that provides flexibility to the device and is structured to rigidize in a second form after application of a quantity of an initiating energy to the material.
摘要翻译：提供了以第一种形式是非刚性的，即柔性的和/或可延展的装置，然后在插入到体内部位之后可变形为刚性或硬化的形式; 对装置施加固化起始能量; 然后将该装置定位在体内部位，在那里其硬化以提供承载功能或其它结构和/或机械功能。该装置包括生物相容护套和密封在护套内的可固化材料。可固化材料以提供该装置的柔性的第一形式提供，并且被构造成在将一定量的起始能量施加到材料之后以第二形式刚性化。

23. 发明授权

US08632524B2 Injectable biocompatible material delivery system 有权
标题翻译：注射生物相容材料输送系统
公开(公告)号：US08632524B2
公开(公告)日：2014-01-21
申请号：US11471993
申请日：2006-06-21
申请人： Hai H. Trieu , Jeff R. Justis , Michael C. Sherman , Dimitri K. Protopsaltis
发明人： Hai H. Trieu , Jeff R. Justis , Michael C. Sherman , Dimitri K. Protopsaltis
IPC分类号： A61K9/22 , A61F2/28
CPC分类号： A61F2/4601 , A61B17/7098 , A61B17/8836 , A61F2002/30583 , A61F2002/4688 , A61F2002/4696 , A61F2210/0085 , A61M2210/1003
摘要： An injectable biocompatible material delivery system is disclosed and can include an injector and a material delivery cannula that can be in fluid communication with the injector. Further, the injectable biocompatible material delivery system can include a light source that can be configured to emit light to at least a portion of the injector, at least a portion of the material delivery cannula, or a combination thereof. Further, the light source can be configured to activate an injectable biocompatible material as it moves through the system.
摘要翻译：公开了可注射的生物相容性材料输送系统，并且可以包括可以与注射器流体连通的注射器和材料输送套管。此外，可注射的生物相容性材料输送系统可以包括光源，其可被配置为向喷射器的至少一部分，材料输送套管的至少一部分或其组合发光。此外，光源可以被配置为在可注射的生物相容性材料移动通过系统时激活。

24. 发明授权

US08303632B2 Techniques for spinal surgery and attaching constructs to vertebral elements 有权
标题翻译：脊柱手术技术和将结构连接到脊椎元件
公开(公告)号：US08303632B2
公开(公告)日：2012-11-06
申请号：US13107631
申请日：2011-05-13
申请人： Michael C. Sherman , Fred J. Molz, IV
发明人： Michael C. Sherman , Fred J. Molz, IV
IPC分类号： A61B17/56
CPC分类号： A61B17/70 , A61B17/025 , A61B17/7035 , A61B17/7089 , A61B17/866 , A61B2017/0256 , A61B2017/3447 , A61B2017/564 , A61F2/0077 , A61F2/30767 , A61F2/4455
摘要： Techniques for spinal surgery include accessing at least one vertebral element of the spinal column. At least one loading member is engaged to the at least one vertebral element. The loading member is allowed to integrate with the bony structure of the vertebral element over time. The integrated loading member is accessed in a second surgical procedure, and can be loaded and/or attached to a construct.
摘要翻译：用于脊柱手术的技术包括进入脊柱的至少一个椎体元件。至少一个装载构件接合到所述至少一个椎骨元件。随着时间的推移，允许装载构件与椎骨元件的骨结构整合。在第二外科手术中访问整合的加载构件，并且可以将其加载和/或附接到构造。

25. 发明申请

US20110270313A1 Spinal Rods Having Different Flexural Rigidities About Different Axes and Methods of Use 有权
标题翻译：具有不同弯曲刚度的脊柱与不同的轴和使用方法
公开(公告)号：US20110270313A1
公开(公告)日：2011-11-03
申请号：US13181474
申请日：2011-07-12
申请人： Jeff R. Justis , Fred J. Molz, IV , Michael C. Sherman
发明人： Jeff R. Justis , Fred J. Molz, IV , Michael C. Sherman
IPC分类号： A61B17/70
CPC分类号： A61B17/7029 , A61B17/7002 , A61B17/701
摘要： A vertebral rod for stabilizing a patient's spine. The rod may include an elongated body with first and second ends and have an elongated cross-sectional shape with a major axis and a minor axis and a centroid positioned at an intersection of the axes. First and second longitudinal channels may extend through the body. The channels may be spaced apart and contained within the body. The body may have a first flexural rigidity along the major axis and a different second flexural rigidity along the minor axis.
摘要翻译：用于稳定患者脊柱的椎骨杆。杆可以包括具有第一和第二端部的细长主体并且具有长轴和短轴的细长横截面形状，并且心轴位于轴线的交点处。第一和第二纵向通道可延伸穿过主体。通道可以间隔开并容纳在体内。主体可以具有沿着长轴的第一弯曲刚度和沿着短轴的不同的第二弯曲刚度。

26. 发明授权

US07901460B2 Intervertebral disc implants and methods for manufacturing and using the same 有权
标题翻译：椎间盘植入物及其制造和使用方法
公开(公告)号：US07901460B2
公开(公告)日：2011-03-08
申请号：US11293070
申请日：2005-12-02
申请人： Michael C. Sherman
发明人： Michael C. Sherman
IPC分类号： A61F2/44
CPC分类号： A61L27/52 , A61B2017/00261 , A61F2/3094 , A61F2/442 , A61F2/4611 , A61F2002/30069 , A61F2002/30075 , A61F2002/30093 , A61F2002/30291 , A61F2002/30293 , A61F2002/30505 , A61F2002/4415 , A61F2002/444 , A61F2002/4635 , A61F2210/0019 , A61F2210/0061 , A61F2220/0025 , A61F2230/0091 , A61L27/446 , A61L2400/16 , A61L2430/38
摘要： Described are intervertebral disc implants that include an elastomeric polymer body, especially a hydrogel body, and a superelastic element. Also described are methods for making and using such implants.
摘要翻译：描述的是椎间盘植入物，其包括弹性聚合物体，特别是水凝胶体和超弹性元件。还描述了制造和使用这种植入物的方法。

27. 发明授权

US07744651B2 Compositions and methods for treating intervertebral discs with collagen-based materials 有权
标题翻译：用胶原基材料治疗椎间盘的组合物和方法
公开(公告)号：US07744651B2
公开(公告)日：2010-06-29
申请号：US11030705
申请日：2005-01-06
申请人： Hai H. Trieu , Michael C. Sherman
发明人： Hai H. Trieu , Michael C. Sherman
IPC分类号： A61F2/44
CPC分类号： A61L27/3834 , A61B17/562 , A61B17/7061 , A61B17/7064 , A61B2017/564 , A61F2/08 , A61F2/4405 , A61F2/4601 , A61F2002/30075 , A61F2002/3008 , A61F2002/30224 , A61F2002/30588 , A61F2002/30677 , A61F2002/4077 , A61F2002/444 , A61F2002/445 , A61F2002/4635 , A61F2210/0061 , A61F2230/0069 , A61F2250/0098 , A61F2310/00365 , A61L27/24 , A61L27/3604 , A61L27/3658 , A61L27/3856 , A61L27/50 , A61L27/54 , A61L31/005 , A61L31/14 , A61L31/18 , A61L2300/402 , A61L2300/406 , A61L2300/41 , A61L2300/414 , A61L2300/44 , A61L2300/64 , A61L2430/24 , A61L2430/38
摘要： A method of augmenting an intervertebral disc nucleus by injecting or otherwise adding to a disc nucleus a plurality of particles of natural, collagen-rich tissue. The mean particle size of the pieces of natural, collagen-rich tissue may be between 0.25 mm and 1.0 mm. The particles may be dehydrated before implantation, and rehydrated after implantation, or they may be implanted in a “wet” state—such as a slurry or gel. Radiocontrast materials may be included to enhance imaging of the injected material. Other additives may include analgesics, antibiotics, proteoglycans, growth factors, stem cells, and/or other cells effective to promote healing and/or proper disc function.
摘要翻译：通过注射或以其它方式将多个天然富含胶原蛋白的组织颗粒加入到椎间盘中来增加椎间盘细胞核的方法。天然富含胶原蛋白的组织的平均粒度可以在0.25mm和1.0mm之间。颗粒可以在植入前脱水，并在植入后再水合，或者它们可以以“湿”状态植入，例如浆料或凝胶。可以包括放射对比材料以增强注射材料的成像。其他添加剂可以包括止痛剂，抗生素，蛋白聚糖，生长因子，干细胞和/或有效促进愈合和/或适当的椎间盘功能的其它细胞。

28. 发明授权

US07731981B2 Collagen-based materials and methods for treating synovial joints 有权
标题翻译：用于治疗滑膜关节的基于胶原的材料和方法
公开(公告)号：US07731981B2
公开(公告)日：2010-06-08
申请号：US11626147
申请日：2007-01-23
申请人： Hai H. Trieu , Michael C. Sherman
发明人： Hai H. Trieu , Michael C. Sherman
IPC分类号： A61K9/00
CPC分类号： A61K9/0024 , A61K9/14 , A61K38/39 , A61K2300/00
摘要： A method of treating a synovial joint by injecting particles of collagen-based material into the joint. The particles may be dehydrated before implantation, and rehydrated after implantation, or they may be implanted in a “wet” state—such as a slurry or gel. Radiocontrast materials may be included to enhance imaging of the injected material. Other additives may include analgesics, antibiotics, proteoglycans, growth factors, and/or other cells effective to promote healing and/or proper joint function.
摘要翻译：通过将胶原基材料的颗粒注入到关节中来治疗滑膜关节的方法。颗粒可以在植入前脱水，并在植入后再水合，或者它们可以以“湿”状态植入，例如浆料或凝胶。可以包括放射对比材料以增强注射材料的成像。其他添加剂可包括止痛剂，抗生素，蛋白聚糖，生长因子和/或有效促进愈合和/或适当关节功能的其它细胞。

29. 发明申请

US20090312806A1 Formed in Place Corpectomy Device 审中-公开
标题翻译：形成位置矫形器装置
公开(公告)号：US20090312806A1
公开(公告)日：2009-12-17
申请号：US12483180
申请日：2009-06-11
申请人： Michael C. Sherman , Samuel M. Shaolian
发明人： Michael C. Sherman , Samuel M. Shaolian
IPC分类号： A61B17/58 , A61F2/44 , A61M29/00
CPC分类号： A61F2/44 , A61F2/441 , A61F2/4611 , A61F2002/30583 , A61F2002/4627 , A61F2210/0085
摘要： An inflatable corpectomy device comprises a balloon, which defines a cavity for receiving a hardenable media. The device can be inserted in an un-inflated form into a space formerly occupied by a diseased or damaged vertebrae bone. When inflated with a hardenable material, the device expands and fills the space. Various bone anchors or plates can be used in combination with the inflatable device to bridge the space and stabilize the spine while the device hardens.
摘要翻译：可充气的椎间盘切除装置包括气囊，其限定用于接收可硬化介质的空腔。该装置可以以未膨胀的形式插入以前由患病或受损的椎骨骨骼占据的空间中。当用可硬化材料充气时，装置膨胀并填充空间。各种骨锚或板可以与充气装置组合使用，以在装置硬化时桥接空间并稳定脊柱。

30. 发明授权

US07563274B2 Surgical instruments and techniques for controlling spinal motion segments with positioning of spinal stabilization elements 有权
标题翻译：用于通过脊柱稳定元件定位来控制脊柱运动节段的手术器械和技术
公开(公告)号：US07563274B2
公开(公告)日：2009-07-21
申请号：US11410727
申请日：2006-04-25
申请人： Jeff R. Justis , Fred J. Molz, IV , Michael C. Sherman
发明人： Jeff R. Justis , Fred J. Molz, IV , Michael C. Sherman
IPC分类号： A61B17/88 , A61B17/70
CPC分类号： A61B17/701 , A61B17/7004 , A61B17/7083 , A61B17/7085 , A61B17/7089
摘要： Elongated connecting elements include bodies having anisotropic cross-sectional shapes defining a first moment of inertia about a first bending axis and a second moment of inertia about a second bending axis that is transverse to the first bending axis. The connecting elements are positioned along one or more spinal motion segments and engaged to vertebrae with anchors with the first and second bending axes in the desired orientation relative to the spinal motion segments.
摘要翻译：细长的连接元件包括具有围绕第一弯曲轴限定第一转动惯量的各向异性横截面形状的主体和围绕横向于第一弯曲轴线的第二弯曲轴线的第二转动惯量。连接元件沿着一个或多个脊柱运动节段定位并且与锚固件接合到具有相对于脊柱运动段的期望取向的第一和第二弯曲轴的锚固件。

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