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21. 发明授权

US07033390B2 Prosthetic heart valve system 有权
公开(公告)号：US07033390B2
公开(公告)日：2006-04-25
申请号：US10336622
申请日：2003-01-02
申请人： Keith M. Johnson , Jack D. Lemmon , Joseph C. Morrow , Timothy R. Ryan
发明人： Keith M. Johnson , Jack D. Lemmon , Joseph C. Morrow , Timothy R. Ryan
IPC分类号： A61F2/24
CPC分类号： A61F2/2439 , A61F2/2412 , A61F2/2427
摘要： A prosthetic heart valve system including a prosthetic heart valve and a deflection device. The deflection device includes a line and a connector assembly including a tensioning component. The line interconnects and passes through free ends of stent posts associated with the heart valve, and is further connected to the tensioning component. The tensioning component is transitionable to a tensioning state in which the line is tensioned to inwardly deflect the stent posts. In this regard, the tensioning component is self-locking relative to the line in the tensioning state, and an entirety of the line extending distal the tensioning device does not extend beyond a stent portion of the heart valve opposite the stent posts. In a preferred embodiment, a holder body is further included, coupled to the heart valve apart from the deflection device.

22. 发明申请

US20100179641A1 MULTI-LAYERED STENTS AND METHODS OF IMPLANTING 审中-公开
标题翻译：多层手术和植入方法
公开(公告)号：US20100179641A1
公开(公告)日：2010-07-15
申请号：US12732329
申请日：2010-03-26
申请人： Timothy R. Ryan , Timothy G. Laske , Philipp Bonhoeffer , Silvia Schievano
发明人： Timothy R. Ryan , Timothy G. Laske , Philipp Bonhoeffer , Silvia Schievano
IPC分类号： A61F2/82
CPC分类号： A61F2/852 , A61F2/2418 , A61F2/2475 , A61F2/90 , A61F2/915 , A61F2/958 , A61F2002/826 , A61F2002/828 , A61F2210/0076 , A61F2220/0008 , A61F2220/0016 , A61F2220/0025 , A61F2220/0058 , A61F2230/0054 , A61F2240/001 , A61F2250/0015 , A61F2250/0018 , A61F2250/006 , Y10T29/49
摘要： A method of percutaneously delivering a multi-layered stent assembly to a desired implantation location of a patient including the steps of radially compressing a multi-layered stent assembly to a compressed size for implantation in a patient, the multi-layered stent assembly including a first stent, a second stent coaxially positioned within at least a portion of a length of the first stent, and a valve, wherein the first stent comprises at least one different material property than the second stent. The method further includes delivering the multi-layered stent assembly to the desired implantation location of the patient using a delivery system and substantially simultaneously expanding the first stent and the second stent of the multi-layered stent assembly at the desired implantation location to a radially expanded size that is larger than the compressed size.
摘要翻译：一种将多层支架组件经皮递送到患者期望的植入位置的方法，包括将多层支架组件径向压缩至压缩尺寸以便植入患者的步骤，所述多层支架组件包括第一支架，同轴地定位在第一支架的长度的至少一部分中的第二支架和阀，其中第一支架包括与第二支架相比的至少一种不同的材料特性。该方法还包括使用递送系统将多层支架组件递送到患者的期望植入位置，并且将所述多层支架组件的第一支架和第二支架基本上同时地扩展到期望的植入位置，以径向扩张尺寸大于压缩尺寸。

23. 发明申请

US20080262593A1 Multi-layered stents and methods of implanting 审中-公开
标题翻译：多层支架和植入方法
公开(公告)号：US20080262593A1
公开(公告)日：2008-10-23
申请号：US12070208
申请日：2008-02-15
申请人： Timothy R. Ryan , Timothy G. Laske , Philipp Bonhoeffer , Silvia Schievano
发明人： Timothy R. Ryan , Timothy G. Laske , Philipp Bonhoeffer , Silvia Schievano
IPC分类号： A61F2/84
CPC分类号： A61F2/852 , A61F2/2418 , A61F2/2475 , A61F2/90 , A61F2/915 , A61F2/958 , A61F2002/826 , A61F2002/828 , A61F2210/0076 , A61F2220/0008 , A61F2220/0016 , A61F2220/0025 , A61F2220/0058 , A61F2230/0054 , A61F2240/001 , A61F2250/0015 , A61F2250/0018 , A61F2250/006 , Y10T29/49
摘要： A method of percutaneously delivering a multi-layered stent assembly to a desired implantation location of a patient including the steps of radially compressing a multi-layered stent assembly to a compressed size for implantation in a patient, the multi-layered stent assembly including a first stent, a second stent coaxially positioned within at least a portion of a length of the first stent, and a valve, wherein the first stent comprises at least one different material property than the second stent. The method further includes delivering the multi-layered stent assembly to the desired implantation location of the patient using a delivery system and substantially simultaneously expanding the first stent and the second stent of the multi-layered stent assembly at the desired implantation location to a radially expanded size that is larger than the compressed size.
摘要翻译：一种将多层支架组件经皮递送到患者期望的植入位置的方法，包括将多层支架组件径向压缩至压缩尺寸以便植入患者的步骤，所述多层支架组件包括第一支架，同轴地定位在第一支架的长度的至少一部分中的第二支架和阀，其中第一支架包括与第二支架相比的至少一种不同的材料特性。该方法还包括使用递送系统将多层支架组件递送到患者的期望植入位置，并且将所述多层支架组件的第一支架和第二支架基本上同时地扩展到期望的植入位置，以径向扩张尺寸大于压缩尺寸。

24. 发明授权

US08157853B2 Delivery systems and methods of implantation for prosthetic heart valves 有权
标题翻译：用于假体心脏瓣膜的输送系统和植入方法
公开(公告)号：US08157853B2
公开(公告)日：2012-04-17
申请号：US12357980
申请日：2009-01-22
申请人： Timothy G. Laske , Timothy R. Ryan , Carolyn C. Majkrzak , Eliot Bloom , Charles Tabor
发明人： Timothy G. Laske , Timothy R. Ryan , Carolyn C. Majkrzak , Eliot Bloom , Charles Tabor
IPC分类号： A61F2/06
CPC分类号： A61F2/2418 , A61F2/2403 , A61F2/2412 , A61F2/243 , A61F2/2436 , A61F2/82 , A61F2002/9505 , A61F2002/9511 , A61F2250/0098
摘要： A method of deploying an implantable stented device in an anatomical location of a patient, including the steps of providing a delivery system with first and second stent engagement structures at its distal end, attaching a first structural element of the stented device to the first stent engagement structure and attaching a second structural element of the stented device to the second stent engagement structure, advancing the stented device to an implantation site, and sequentially disengaging the first structural element of the stented device from the first stent engagement structure of the delivery system and then disengaging the second structural element of the stented device from the second stent engagement structure.
摘要翻译：一种将可植入支架装置部署在患者的解剖位置的方法，包括以下步骤：在其远端处提供具有第一和第二支架接合结构的输送系统，将支架装置的第一结构元件附接到第一支架接合结构并将支架装置的第二结构元件附接到第二支架接合结构，将支架装置推进到植入部位，并且将支架装置的第一结构元件与递送系统的第一支架接合结构顺序地分离，然后将支架装置的第二结构元件与第二支架接合结构分离。

25. 发明申请

US20090192585A1 Delivery Systems and Methods of Implantation for Prosthetic Heart Valves 有权
标题翻译：假体心脏瓣膜植入系统和方法
公开(公告)号：US20090192585A1
公开(公告)日：2009-07-30
申请号：US12357958
申请日：2009-01-22
申请人： Eliot Bloom , Timothy R. Ryan , Charles Tabor , Timothy G. Laske , Carolyn C. Majkrzak
发明人： Eliot Bloom , Timothy R. Ryan , Charles Tabor , Timothy G. Laske , Carolyn C. Majkrzak
IPC分类号： A61F2/06
CPC分类号： A61F2/2418 , A61F2/2403 , A61F2/2412 , A61F2/243 , A61F2/2436 , A61F2/82 , A61F2002/9505 , A61F2002/9511 , A61F2250/0098
摘要： A delivery system for delivering a stented prosthetic heart valve to a lumen of a patient, the delivery system including a tubular body having a proximal end and a distal end, and a plurality of wires extending from the distal end of the tubular body, wherein each of the wires has a distal end that is coiled for engagement with a stent of a stented prosthetic heart valve.
摘要翻译：一种用于将支架假体心脏瓣膜输送到患者的内腔的输送系统，所述输送系统包括具有近端和远端的管状体以及从所述管状体的远端延伸的多根线，其中每个的线具有被卷绕以与支架假体心脏瓣膜的支架接合的远端。

26. 发明授权

US08029564B2 Prosthetic heart valve system 有权
标题翻译：假心脏瓣膜系统
公开(公告)号：US08029564B2
公开(公告)日：2011-10-04
申请号：US12372115
申请日：2009-02-17
申请人： Keith M. Johnson , Jack D. Lemmon , Joseph C. Morrow , Timothy R. Ryan
发明人： Keith M. Johnson , Jack D. Lemmon , Joseph C. Morrow , Timothy R. Ryan
IPC分类号： A61F2/24
CPC分类号： A61F2/2439 , A61F2/2412 , A61F2/2427
摘要： A prosthetic heart valve system including a prosthetic heart valve and a deflection device. The deflection device includes a line and a connector assembly including a tensioning component. The line interconnects and passes through free ends of stent posts associated with the heart valve, and is further connected to the tensioning component. The tensioning component is transitionable to a tensioning state in which the line is tensioned to inwardly deflect the stent posts. In this regard, the tensioning component is self-locking relative to the line in the tensioning state, and an entirety of the line extending distal the tensioning device does not extend beyond a stent portion of the heart valve opposite the stent posts. In a preferred embodiment, a holder body is further included, coupled to the heart valve apart from the deflection device.
摘要翻译：一种假体心脏瓣膜系统，包括假体心脏瓣膜和偏转装置。偏转装置包括线和包括张紧部件的连接器组件。线路连接并穿过与心脏瓣膜相关联的支架支柱的自由端，并进一步连接到张紧部件。张紧部件可转换到张紧状态，其中线被张紧以使支架柱向内偏转。在这方面，张紧部件相对于处于张紧状态的线是自锁的，并且延伸远离张紧装置的线的整体不延伸超过与支架柱相对的心脏瓣膜的支架部分。在优选实施例中，进一步包括保持器主体，其与偏转装置相连接到心脏瓣膜。

27. 发明申请

US20080161911A1 REPLACEMENT PROSTHETIC HEART VALVE, SYSTEM AND METHOD OF IMPLANT 审中-公开
标题翻译：更换前置心脏瓣膜，系统和植入方法
公开(公告)号：US20080161911A1
公开(公告)日：2008-07-03
申请号：US12048768
申请日：2008-03-14
申请人： Jose M. Revuelta , Jack D. Lemmon , Timothy R. Ryan
发明人： Jose M. Revuelta , Jack D. Lemmon , Timothy R. Ryan
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2220/0008 , A61F2220/0016 , A61F2230/0013 , A61F2230/0078 , A61F2230/008 , A61F2250/0039 , A61F2250/0063
摘要： A method of functionally replacing a previously implanted prosthetic heart valve. The method includes positioning a replacement prosthetic heart valve within an internal region defined by the previously implanted prosthetic heart valve. The replacement prosthetic heart valve is then physically docked to the previously implanted prosthetic heart valve. With this technique, the previously implanted prosthetic heart valve serves as a platform for securement of the replacement prosthetic heart valve to the patient's native tissue.
摘要翻译：功能性替代以前植入的假体心脏瓣膜的方法。该方法包括将置换的假体心脏瓣膜定位在由先前植入的假体心脏瓣膜限定的内部区域内。然后，将置换的假体心脏瓣膜物理对接到先前植入的假体心脏瓣膜。利用这种技术，先前植入的假体心脏瓣膜用作将替换的假体心脏瓣膜固定到患者的天然组织的平台。

28. 发明申请

US20090198316A1 Delivery Systems and Methods of Implantation for Prosthetic Heart Valves 有权
标题翻译：假体心脏瓣膜植入系统和方法
公开(公告)号：US20090198316A1
公开(公告)日：2009-08-06
申请号：US12357980
申请日：2009-01-22
申请人： Timothy G. Laske , Timothy R. Ryan , Carolyn C. Majkrzak , Eliot Bloom , Charles Tabor
发明人： Timothy G. Laske , Timothy R. Ryan , Carolyn C. Majkrzak , Eliot Bloom , Charles Tabor
IPC分类号： A61F2/06 , A61F2/24
CPC分类号： A61F2/2418 , A61F2/2403 , A61F2/2412 , A61F2/243 , A61F2/2436 , A61F2/82 , A61F2002/9505 , A61F2002/9511 , A61F2250/0098
摘要： A method of deploying an implantable stented device in an anatomical location of a patient, including the steps of providing a delivery system with first and second stent engagement structures at its distal end, attaching a first structural element of the stented device to the first stent engagement structure and attaching a second structural element of the stented device to the second stent engagement structure, advancing the stented device to an implantation site, and sequentially disengaging the first structural element of the stented device from the first stent engagement structure of the delivery system and then disengaging the second structural element of the stented device from the second stent engagement structure.
摘要翻译：一种将可植入支架装置部署在患者的解剖位置的方法，包括以下步骤：在其远端处提供具有第一和第二支架接合结构的输送系统，将支架装置的第一结构元件附接到第一支架接合结构并将支架装置的第二结构元件附接到第二支架接合结构，将支架装置推进到植入部位，并且将支架装置的第一结构元件与递送系统的第一支架接合结构顺序地分离，然后将支架装置的第二结构元件与第二支架接合结构分离。

29. 发明授权

US08591570B2 Prosthetic heart valve for replacing previously implanted heart valve 有权
标题翻译：假体心脏瓣膜替换以前植入的心脏瓣膜
公开(公告)号：US08591570B2
公开(公告)日：2013-11-26
申请号：US12048725
申请日：2008-03-14
申请人： José M. Revuelta , Jack D. Lemmon , Timothy R. Ryan
发明人： José M. Revuelta , Jack D. Lemmon , Timothy R. Ryan
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2220/0008 , A61F2220/0016 , A61F2230/0013 , A61F2230/0078 , A61F2230/008 , A61F2250/0039 , A61F2250/0063
摘要： A method of functionally replacing a previously implanted prosthetic heart valve. The method includes positioning a replacement prosthetic heart valve within an internal region defined by the previously implanted prosthetic heart valve. The replacement prosthetic heart valve is then physically docked to the previously implanted prosthetic heart valve. With this technique, the previously implanted prosthetic heart valve serves as a platform for securement of the replacement prosthetic heart valve to the patient's native tissue.
摘要翻译：功能性替代以前植入的假体心脏瓣膜的方法。该方法包括将置换的假体心脏瓣膜定位在由先前植入的假体心脏瓣膜限定的内部区域内。然后，将置换的假体心脏瓣膜物理对接到先前植入的假体心脏瓣膜。利用这种技术，先前植入的假体心脏瓣膜用作将替换的假体心脏瓣膜固定到患者的天然组织的平台。

30. 发明授权

US08535374B2 Annuloplasty device for tricuspid valve repair 有权
公开(公告)号：US08535374B2
公开(公告)日：2013-09-17
申请号：US12011482
申请日：2008-01-25
申请人： Jerald Redmond , Timothy R. Ryan , Jason L. Quill , Alexander J. Hill , Michael A. Gloss
发明人： Jerald Redmond , Timothy R. Ryan , Jason L. Quill , Alexander J. Hill , Michael A. Gloss
IPC分类号： A61F2/24
CPC分类号： A61F2/2445
摘要： Annuloplasty device for implantation adjacent an annulus of a tricuspid valve, the annulus comprising anterior, posterior and septal aspects adjacent anterior, posterior and septal leaflets, respectively, of the tricuspid valve, the device comprising: a ring body comprising: an anterior portion, a posterior portion and a septal portion shaped to conform to, and for implantation adjacent, the anterior, posterior and septal aspects of the annulus, respectively; and first and second ends; wherein the ring body is curvilinear, with substantially no flat portions, forming a shape, and the ends are configured such that when the device is implanted, the first end will be located near the junction of the septal and anterior aspects of the annulus and the second end will be located near the septal aspect of the annulus. Related methods.

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