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21. 发明申请

US20150168424A1 IGFBP2 Biomarker 审中-公开
标题翻译： IGFBP2生物标志物
公开(公告)号：US20150168424A1
公开(公告)日：2015-06-18
申请号：US14556402
申请日：2014-12-01
申请人： Yan Wang
发明人： Yan Wang
IPC分类号： G01N33/68 , A61K39/395 , A61K45/06 , C07K16/28
CPC分类号： G01N33/6872 , A61K39/39558 , A61K45/06 , A61K2039/505 , C07K16/2863 , C07K2317/56 , C07K2317/565 , C07K2317/76 , G01N2333/65
摘要： The present invention provides method for quickly and conveniently determining if a given treatment regimen of IGF1R inhibitor is sufficient, e.g., to saturate IGF1R receptors in the body of a subject. Several clinically relevant determinations may be made based on this point, including, for example, whether the dosage of the regimen is sufficient or should be increased.
摘要翻译：本发明提供了用于快速和方便地确定给定的IGF1R抑制剂治疗方案是否足够的方法，例如饱和受试者体内的IGF1R受体。可以基于这一点进行若干临床相关的测定，包括例如方案的剂量是否足够或应当增加。

22. 发明申请

US20150033326A1 System and Method for Unlocking Screen 有权
标题翻译：解锁屏幕的系统和方法
公开(公告)号：US20150033326A1
公开(公告)日：2015-01-29
申请号：US14379575
申请日：2012-05-28
申请人： Wen Fang , Yusheng Cao , Yan Wang
发明人： Wen Fang , Yusheng Cao , Yan Wang
IPC分类号： G06F21/60 , G06F3/0488 , G06F3/0484
CPC分类号： G06F21/60 , G06F3/04842 , G06F3/0488 , G06F3/04883 , H04M1/67 , H04M2250/22
摘要： Disclosed are a method for unlocking a screen and a system for installing a screen. It is determined whether to unlock the screen by calculating an angle between a starting position and a current position of a touch point on the screen with the unlocking reference point as a vertex of the angle. With a technical solution of the disclosure, no path or destination position for screen unlocking is defined, with more casual operation, enhanced user experience, and simpler setting, thereby facilitating usage. Moreover, unlocking by mistake can also be prevented by the setting.
摘要翻译：公开了一种用于解锁屏幕的方法和用于安装屏幕的系统。通过使用解锁参考点作为角度的顶点，通过计算屏幕上的触摸点的开始位置和当前位置之间的角度来确定是否解锁屏幕。通过本公开的技术方案，没有定义用于屏幕解锁的路径或目的地位置，具有更多的休闲操作，增强的用户体验和更简单的设置，从而便于使用。此外，也可以通过设定来防止错误解锁。

23. 发明授权

US08765030B2 Preparation of an enteric release system 有权
标题翻译：肠溶释放系统的准备
公开(公告)号：US08765030B2
公开(公告)日：2014-07-01
申请号：US13475645
申请日：2012-05-18
申请人： Ahmad Akashe , Anilkumar Ganapati Gaonkar , Les Lawrence , Amado R. Lopez , Ronald L. Meibach , Dana Sebesta , Yan Wang , James D. White
发明人： Ahmad Akashe , Anilkumar Ganapati Gaonkar , Les Lawrence , Amado R. Lopez , Ronald L. Meibach , Dana Sebesta , Yan Wang , James D. White
IPC分类号： A61K9/127
CPC分类号： A61K36/48 , A23P10/35 , A61K8/11 , A61K8/645 , A61K8/927 , A61K9/0095 , A61K9/5015 , A61K9/5052 , A61K9/5063 , A61K31/015 , A61K31/045 , A61K31/05 , A61K31/31 , A61K2800/412 , A61Q13/00 , A61K2300/00
摘要： Hydrophobic liquids are microencapsulated by an enteric matrix in an environment substantially free of organic solvents, the process including forming an emulsion of the enteric material and hydrophobic liquid in water, the emulsion titrated with an acid to form a particulate precipitate of the microencapsulated hydrophobic liquid in an enteric matrix.
摘要翻译：疏水性液体在基本上不含有机溶剂的环境中由肠溶基质微胶囊化，该方法包括在肠液中形成肠溶性物质和疏水性液体的乳液，用酸滴定乳液，以形成微胶囊化疏水液体的颗粒状沉淀物肠溶矩阵

24. 发明授权

US08724587B2 Method, apparatus, and system for sending a data packet 有权
标题翻译：用于发送数据包的方法，装置和系统
公开(公告)号：US08724587B2
公开(公告)日：2014-05-13
申请号：US13234911
申请日：2011-09-16
申请人： Yan Wang , Bo Lin , Yuhong Liu
发明人： Yan Wang , Bo Lin , Yuhong Liu
IPC分类号： H04W4/00 , H04W36/18 , H04W52/54 , H04W36/00
CPC分类号： H04W36/18 , H04W36/02 , H04W52/54
摘要： The present invention relates to radio communications technologies and discloses a method, an apparatus, and a system for sending a data packet to avoid repeated forwarding of data when a user equipment hands over between an access point and an evolved NodeB. The method includes: receiving, by an evolved NodeB, a data packet sent by a core network and sending the data packet to a current access point; and keeping caching the data packet on the evolved NodeB before determining that a user equipment has correctly received the data packet from the current access point. The present invention is applicable to data transmission in a network.
摘要翻译：本发明涉及无线电通信技术，并且公开了一种方法，装置和系统，用于当用户设备在接入点和演进节点B之间切换时，发送数据分组以避免数据重复转发。该方法包括：由演进的节点B接收由核心网发送的数据分组，并将数据分组发送到当前接入点; 并且在确定用户设备已经从当前接入点正确地接收到数据分组之前，将数据分组保持缓存在演进的节点B上。本发明适用于网络中的数据传输。

25. 发明授权

US08476045B2 Methods of using improved polymerases 有权
公开(公告)号：US08476045B2
公开(公告)日：2013-07-02
申请号：US13560075
申请日：2012-07-27
申请人： Yan Wang , Peter Vander Horn , Lei Xi
发明人： Yan Wang , Peter Vander Horn , Lei Xi
IPC分类号： C12P19/34
CPC分类号： C12N15/10 , C07K14/195 , C07K2319/00 , C07K2319/80 , C12N9/1252 , C12N15/62 , C12P19/34 , C12Q1/686 , C12Y207/07007
摘要： This invention provides for methods of sequencing and performing polymerase reactions using an improved generation of nucleic acid polymerases. The improvement is the fusion of a sequence-non-specific nucleic-acid-binding domain to the enzyme in a manner that enhances the processivity of the polymerase.

26. 发明授权

US08453726B2 Corrugated settling cup and a multi-cup uniform flux gas anchor 有权
标题翻译：波纹沉降杯和多杯均匀通量气锚
公开(公告)号：US08453726B2
公开(公告)日：2013-06-04
申请号：US12673064
申请日：2008-08-22
申请人： Demin Wang , Yan Wang , Jun Wan , Shumin Zhang , Rongjie Zhu , Li Li
发明人： Demin Wang , Yan Wang , Jun Wan , Shumin Zhang , Rongjie Zhu , Li Li
IPC分类号： E21B43/38
CPC分类号： E21B43/38 , E21B43/127 , F04B47/02
摘要： A corrugated settling cup (5) is provided, wherein the cup has a cup body, an opening and a location step (52) are provided at the bottom (55) of the cup body, several location holes (53) are formed at the top of the location step (52), location projections (54) corresponding to the location holes (53) are formed at the bottom (55) of the corrugated settling cup (5), wherein the external profile of the corrugated settling cup body rises along the axial direction in a corrugated shape. A multi-cup uniform flux gas anchor is provided, wherein the gas anchor includes a central pipe (7), several corrugated settling cups (5), several settling cups protection bodies (6) and a well-flushing valve (9), wherein the external profile of the corrugated settling cup body rises along the axial direction in a corrugated shape.
摘要翻译：提供了一种波纹沉降杯（5），其中杯体具有杯体，在杯体的底部（55）设有开口和位置台阶（52），多个位置孔（53）形成在在波纹沉降杯（5）的底部（55）形成位置台阶（52）的顶部，对应于定位孔（53）的定位突起（54），其中波纹沉降杯体的外部轮廓上升沿轴向以波纹形状。提供了一种多杯均匀的通量气体锚定器，其中气锚包括中心管（7），多个波纹沉降杯（5），多个沉降杯保护体（6）和井冲洗阀（9），其中波纹沉降杯体的外部轮廓沿轴向方向以波纹形状上升。

27. 发明授权

US08426431B2 Substituted 2-aminoacetamides and the use thereof 有权
标题翻译：取代的2-氨基乙酰胺及其用途
公开(公告)号：US08426431B2
公开(公告)日：2013-04-23
申请号：US12986587
申请日：2011-01-07
申请人： Nancy C. Lan , Yan Wang , Sui Xiong Cai
发明人： Nancy C. Lan , Yan Wang , Sui Xiong Cai
IPC分类号： A61K31/505 , A61K31/47 , A61K31/165
CPC分类号： C07C233/05 , A61K31/165 , C07C237/06 , C07C237/08 , C07C2601/14 , C07D211/46 , C07D213/65 , C07D213/68 , C07D215/20 , C07D239/34 , C07D241/08 , C07D309/12 , C07D317/64
摘要： The invention is directed to substituted 2-aminoacetamides represented by formula (II): and to pharmaceutically acceptable salts and prodrugs thereof, wherein the substituents are defined herein. The invention is also directed to the use of substituted 2-aminoacetamides in methods for the treatment of neuronal damage following global and focal ischemia, and for the treatment, prevention or amelioration of pain, anxiety, or manic depression, as anticonvulsants, as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.
摘要翻译：本发明涉及由式（II）表示的取代的2-氨基乙酰胺及其药学上可接受的盐和前药，其中取代基在本文中定义。本发明还涉及取代的2-氨基乙酰胺在治疗全球和局灶性缺血后的神经元损伤的方法中的用途，以及用作治疗，预防或改善作为抗惊厥药物的抗痉挛剂的疼痛，焦虑或躁狂抑郁症，作为局部麻醉剂，作为抗心律失常药物和治疗或预防糖尿病性神经病变。

28. 发明授权

US08426132B2 Quantitative amplification with a labeled probe and 3′ to 5′ exonuclease activity 有权
标题翻译：用标记的探针和3'至5'核酸外切酶活性进行定量扩增
公开(公告)号：US08426132B2
公开(公告)日：2013-04-23
申请号：US12264200
申请日：2008-11-03
申请人： Bin Li , Lei Xi , Yan Wang , Peter B. Vander Horn
发明人： Bin Li , Lei Xi , Yan Wang , Peter B. Vander Horn
IPC分类号： C12Q1/68 , C12P19/34
CPC分类号： C12Q1/6851 , C12Q2561/101 , C12Q2525/161 , C12Q2521/101 , C12Q2537/143 , C12Q2527/143
摘要： This invention provides methods and kits for performing a quantitative amplification reaction. The method employs a polymerase enzyme and an enzyme having a 3′ to 5′ exonuclease activity that cleaves the 3′ oligonucleotide of the probe.
摘要翻译：本发明提供了进行定量扩增反应的方法和试剂盒。该方法采用聚合酶和具有切割探针的3'寡核苷酸的3'至5'核酸外切酶活性的酶。

29. 发明申请

US20120258460A1 Sso7-Polymerase Conjugates with Decreased Non-Specific Activity 有权
标题翻译：具有降低的非特异性活性的Sso7-聚合酶偶联物
公开(公告)号：US20120258460A1
公开(公告)日：2012-10-11
申请号：US13371126
申请日：2012-02-10
申请人： Man Cheng , Yan Wang , John Sullivan
发明人： Man Cheng , Yan Wang , John Sullivan
IPC分类号： C12Q1/68 , C12N9/96
CPC分类号： C12N9/1241 , C07K2319/80 , C12N9/1252 , C12N9/96 , C12Q1/686
摘要： Improved Sso7-polymerase conjugate proteins are provided
摘要翻译：提供了改进的Sso7聚合酶缀合蛋白

30. 发明申请

US20120198110A1 MAIN BOARD AND METHOD FOR DYNAMICALLY CONFIGURING PCIE PORTS THEREOF 有权
标题翻译：主板和动态配置PCIE端口的方法
公开(公告)号：US20120198110A1
公开(公告)日：2012-08-02
申请号：US13194572
申请日：2011-07-29
申请人： Yan Wang , Yao Guo
发明人： Yan Wang , Yao Guo
IPC分类号： G06F13/00
CPC分类号： G06F13/4081 , G06F2213/0026
摘要： A main board and a method for dynamically configuring PCIE ports thereof. The main board comprises a PCIE slot, a detecting circuit, an ROM, a chipset and a modifying circuit. The chipset comprises a Management Engine controller and several PCIE ports. The chipset has a Management Engine function or a similar function. The detecting circuit detects the PCIE slot to generate a current state parameter. The ROM stores a default configuration data. The modifying circuit coupled between the chipset and the ROM determines whether the default configuration data needs to be modified according to the current state parameter. When the default configuration data needs to be modified, the modifying circuit modifies the default configuration data according to the current state parameter, so that the Management Engine controller initially configures the PCIE ports according to the modified default configuration data. Thus, the dynamical configuration of the chipset PCIE ports is realized.
摘要翻译：一种用于动态配置其PCIE端口的主板和方法。主板包括PCIE插槽，检测电路，ROM，芯片组和修改电路。该芯片组包括一个管理引擎控制器和几个PCIE端口。该芯片组具有管理引擎功能或类似的功能。检测电路检测PCIE插槽以产生当前状态参数。 ROM存储默认配置数据。耦合在芯片组和ROM之间的修改电路确定是否需要根据当前状态参数修改默认配置数据。当需要修改默认配置数据时，修改电路将根据当前状态参数修改默认配置数据，以便管理引擎控制器根据修改的默认配置数据初始配置PCIE端口。因此，实现了芯片组PCIE端口的动态配置。

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