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21. 发明专利

CA2661224A1 BORRELIA ANTIGENS 未知
公开(公告)号：CA2661224A1
公开(公告)日：2008-03-20
申请号：CA2661224
申请日：2007-09-14
申请人： INTERCELL AG
发明人： POLJAK ALBINA , GELBMANN DIETER , LUNDBERG URBAN , VON GABAIN ALEXANDER , NOIGES BIRGIT , NAGY ESZTER , TRISKA CHRISTINE , MEINKE ANDREAS
IPC分类号： C07K14/20
摘要： The present invention relates to isolated nucleic acid molecules which en code a protein, isolated nucleic acid molecules which encode a hyperimmune s erum reactive antigen, a vector which comprises such nucleic acid molecule, a host cell comprising such vector, a hyperimmune reactive antigen from Borr elia species, proteins which are preferably hyperimmune serum reactive antig ens, hyperimmune serum reactive antigens, antigens, a process for producing such proteins, hyperimmune serum reactive antigens or antigens, a process fo r producing a cell which expresses such protein, hyperimmune serum reactive antigen or antigen, an antibody binding to such protein, hyperimmune serum r eactive antigen or antigen, a hybridoma cell producing such antibody, method s for producing such antibody, a pharmaceutical composition comprising such nucleic acid molecule, protein, hyperimmune serum reactive antigen, antigen or antibody, the use of such nucleic acid molecule, protein, hyperimmune ser um reactive antigen, antigen or antibody for the manufacture of a medicament , methods for identifying an antagonist capable of reducing or inhibiting th e interaction activity of such protein, hyperimmune serum reactive antigen o r antigen, methods for diagnosing an infection and methods for the treatment of an infection. More specifically such proteins, hyperimmune serum reactiv e antigens or antigens are produced by or associated with bacterial pathogen s causing Lyme disease or bacterial infections caused by Borrelia burgdorfer i s.l.

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