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21. 发明授权

US06928139B2 Method and device for sampling tissue during a radiological examination 失效
标题翻译：在放射学检查期间取样组织的方法和装置
公开(公告)号：US06928139B2
公开(公告)日：2005-08-09
申请号：US10125312
申请日：2002-04-17
申请人： Serge Muller , Andreas Rick
发明人： Serge Muller , Andreas Rick
IPC分类号： A61B10/02 , A61B6/00 , A61B6/04
CPC分类号： A61B6/502 , A61B6/481
摘要： A method and device for sampling a fragment of tissue in which a contrast medium is injected into an organ to be examined and highlights parts containing that contrast medium in an image obtained by emitting a beam of X-rays. At least one pair of radiographic images is captured from a first position and a second position of an X-ray emitter during a phase of increasing attenuation due to the contrast medium. A specific area is identified from the pair of images in which a tissue fragment is to be sampled. The images of the pair of images are combined to determine the three-dimensional coordinates of the specific area.
摘要翻译：一种将造影剂注射到待检查器官中的组织碎片采样的方法和装置，并且通过发射X射线束而获得的图像中突出包含该造影剂的部分。由于造影剂在衰减增加的阶段中，从X射线发射器的第一位置和第二位置捕获至少一对放射照相图像。从要对其进行采样的组织片段的一对图像中识别特定区域。组合这对图像的图像以确定特定区域的三维坐标。

22. 发明申请

US20050135695A1 Method for radiological image processing 失效
标题翻译：放射图像处理方法
公开(公告)号：US20050135695A1
公开(公告)日：2005-06-23
申请号：US10999874
申请日：2004-11-30
申请人： Sylvain Bernard , Serge Muller , Xavier Bouchevreau
发明人： Sylvain Bernard , Serge Muller , Xavier Bouchevreau
IPC分类号： A61B6/00 , G06K9/00 , G06T1/00 , G06T5/00 , G06T5/10 , G06T5/20 , G06T7/00 , G06T7/40 , H04N5/325
CPC分类号： G06K9/3233 , G06K2209/053 , G06T5/008 , G06T5/10 , G06T5/20 , G06T7/0012 , G06T2207/20012 , G06T2207/30068
摘要： A method for radiological image processing that includes: locating, on a radiological image provided by an imaging device, elements that may constitute signs of micro-calcification and displaying an image on which the intensity of elements thus localized is enhanced.
摘要翻译：一种用于放射图像处理的方法，包括：在由成像装置提供的放射线图像上定位可以构成微钙化迹象的元件，并显示其上增强了如此定位的元件的强度的图像。

23. 发明授权

US06718056B1 Method of automatic determination of the contrast and brightness of a digital radiographic image 失效
标题翻译：自动确定数字放射照相图像的对比度和亮度的方法
公开(公告)号：US06718056B1
公开(公告)日：2004-04-06
申请号：US09450489
申请日：1999-11-29
申请人： Sylvie Bothorel , Serge Muller , Jean Lienard , Andreas Rick , François Nicolas
发明人： Sylvie Bothorel , Serge Muller , Jean Lienard , Andreas Rick , François Nicolas
IPC分类号： G06K900
CPC分类号： G06T7/0002 , G06T5/009 , G06T5/40 , G06T2207/10116 , G06T2207/30068 , G06T2207/30168 , H04N1/4074
摘要： The method comprises a histogram of the radiographed image, i.e., a real histogram, a mathematical model of the image chain and the object obtained by calibration. The mathematical model of the image chain and the object and a set of parameters of acquisition, of the detector, of the positioner and of the object are used to determine two values of gray level, gray min and gray max, delimiting a useful zone and the part below gray min and the part above gray max are suppressed in the real histogram, i.e., a limited histogram. A set of rules is applied to the limited histogram in order to determine the level of brightness (WL) and the contrast (WW) is obtained from the brightness and possibly from one or more parameters selected by the user or fixed a priori.
摘要翻译：该方法包括射线照相图像的直方图，即真实直方图，图像链的数学模型和通过校准获得的对象。图像链和对象的数学模型以及采集，定位器和对象的检测参数的一组参数用于确定灰度级，灰度最小值和灰度最大值两个值，定义有用区域，灰色最小值以下的部分和灰度最大值部分在实际直方图中被抑制，即有限的直方图。将一组规则应用于有限直方图，以便确定亮度水平（WL），并且可以从亮度获得对比度（WW），并且可能从用户选择的一个或多个参数获得或先验固定。

24. 发明授权

US5544219A Procedure for automatic position-finding of points of interest during a mammography examination using stereotactic technique 失效
标题翻译：使用立体定位技术在乳房X线照相检查期间自动定位感兴趣的程序
公开(公告)号：US5544219A
公开(公告)日：1996-08-06
申请号：US332743
申请日：1994-11-01
申请人： Serge Muller , Michel Grimaud , Robert Heidsieck
发明人： Serge Muller , Michel Grimaud , Robert Heidsieck
IPC分类号： A61B19/00 , G06T5/20 , G06T5/30 , G06T7/00 , H04N13/00 , A61B6/12
CPC分类号： G06T5/30 , A61B90/10 , G06T7/0042 , G06T2207/10012 , G06T2207/30068 , H04N2013/0074
摘要： A process is disclosed which involves automatic position-finding for a point of interest of an object that exhibits high contrast as compared with surrounding tissues, the process being carried out by means of a stereotactic photographic device that includes a digital image acquisition system. The process includes a number of steps for each image belonging to the pair of stereotactic images. An initial analysis of a histogram of the image pixels are made, and a subsequent determination is made of a threshold corresponding to the difference between the high contrast objects and the surrounding tissues. A subsequent determination is made of the threshold of the image, in order to obtain a binary image incorporating two gray levels. This is followed by the filtering of the threshold determined image in the preceding step, based on morphological criteria of the object in which the point of interest is located. This operation is designed to obtain a segmented projection of the object of interest. This is followed by the localization of the point of interest in the image reference mark. Utilization of the process is for stereotactic examinations performed during mammography.
摘要翻译：公开了一种涉及与周围组织相比显示高对比度的物体的感兴趣点的自动位置查找的过程，该过程通过包括数字图像采集系统的立体定向照相装置进行。该过程包括属于一对立体定向图像的每个图像的多个步骤。进行图像像素的直方图的初始分析，并且随后确定对应于高对比度对象与周围组织之间的差的阈值。随后确定图像的阈值，以便获得并入两个灰度级的二进制图像。接下来是基于目标位置的对象的形态标准对前一步骤中的阈值确定图像的过滤。该操作被设计为获得感兴趣对象的分段投影。接下来是图像参考标记中的兴趣点的本地化。该过程的利用是在乳房X线照相术期间进行的立体定向检查。

25. 发明授权

US08798348B2 Method for processing images obtained by tomosynthesis and associated device 有权
标题翻译：用于处理通过层析合成和相关设备获得的图像的方法
公开(公告)号：US08798348B2
公开(公告)日：2014-08-05
申请号：US12371968
申请日：2009-02-17
申请人： Serge Muller , Sylvie Puong
发明人： Serge Muller , Sylvie Puong
IPC分类号： G06K9/00
CPC分类号： G06T11/006 , G06T2211/436
摘要： A processing method for images obtained by tomosynthesis comprising acquisition of a plurality of 2D projection images of a region of interest of a patient; reconstruction of a 3D digital image from the acquired 2D projection images. An embodiment of the method is characterized in that it comprises: detection of an object in the reconstructed 3D image; estimation of a thickness limit characteristic of a contrast default of the voxels for a diameter of the object; estimation of the thickness of the object; comparison of the thickness of the object to the thickness limit; and in that if the thickness of the object is less than the thickness limit, the method further comprises application at least to the voxels of the object in the reconstructed image of a multiplicative corrective factor equal to the ratio between the thickness limit and the thickness of the object.
摘要翻译：一种通过层析合成获得的图像的处理方法，包括获取患者感兴趣区域的多个2D投影图像; 从所获取的2D投影图像重建3D数字图像。该方法的一个实施例的特征在于它包括：检测重建的3D图像中的对象; 估计对象的直径的体素的对比度默认值的厚度限制特性; 估计物体的厚度; 对象厚度与厚度限制的比较; 并且如果物体的厚度小于厚度限制，则该方法还包括至少对重建图像中的物体的体素应用等于在厚度极限和厚度之间的比率的乘法校正因子物体。

26. 发明授权

US08335809B2 Procedure for deriving a three-dimensional digital mask starting from a series of two-dimensional masks, plus a device for doing this 有权
标题翻译：从一系列二维掩模开始的三维数字掩模的推导以及用于执行此操作的设备的步骤
公开(公告)号：US08335809B2
公开(公告)日：2012-12-18
申请号：US12339209
申请日：2008-12-19
申请人： Giovanni Palma , Serge Muller , Razvan Iordache
发明人： Giovanni Palma , Serge Muller , Razvan Iordache
IPC分类号： G06F17/17 , G06K9/00
CPC分类号： G06T11/005 , A61B6/027 , G06T2207/10112 , G06T2207/30068
摘要： A derivation procedure for a three-dimensional digital mask from a series of two-dimensional masks in a radiographic device containing a source (S) of X-rays, a means of recording and a volume of interest hat contains the object to be X-rayed located between the source (S) and the means of recording consists of an extrapolation of each mask Mθ2 includes determining a last segment 1fin beyond the limits of the means of recording; and working out a two-dimensional mask Mγ associated with a position Sγ of the source, for any angle γ included in the angular range θ2 to θ1 (a position close to θ2). For every parallel segment 1 located between segment d (or d′ respectively) and segment 1fin, the procedure further includes deriving a three-dimensional mask (21) of the object for each voxel at the intersection of plane P1θ2 and the volume of interest; and projecting the three-dimensional mask onto the segment 1.
摘要翻译：一种用于在包含X射线源（S）的X射线照相装置中的一系列二维掩模的三维数字掩模的导出程序，记录装置和感兴趣的体积，位于源（S）和记录装置之间的射线包括每个掩模M＆amp;的外插; 2包括确定超出记录装置限制的最后段lfin; 并且对于包括在角度范围＆amp;角度中的任何角度γ，生成与源的位置Sγ相关联的二维掩模Mγ; 2至＆amp; thetas; 1（接近于＆thetas; 2的位置）。对于位于段d（或d'）和段lfin之间的每个并行段1，该过程还包括在平面P1和坐标2与所关心的体积的交点处导出每个体素的对象的三维掩模; 并将三维掩模投射到片段1上。

27. 发明申请

US20110261927A1 METHOD AND APPARATUS FOR TOMOSYNTHESIS PROJECTION IMAGING FOR DETECTION OF RADIOLOGICAL SIGNS 有权
标题翻译：用于检测放射性信号的肿瘤放射成像的方法和装置
公开(公告)号：US20110261927A1
公开(公告)日：2011-10-27
申请号：US13176357
申请日：2011-07-05
申请人： Gero L. Peters , Serge Muller , Sylvain Bernard , Razvan Jordache
发明人： Gero L. Peters , Serge Muller , Sylvain Bernard , Razvan Jordache
IPC分类号： A61B6/04 , G06K9/00
CPC分类号： G06T7/0012 , G06T2200/04 , G06T2207/10116 , G06T2207/30068
摘要： A method of image processing in a radiological apparatus includes reconstructing a 3D image of a body from a set of radiography projection images, locating structures presumed to be representative of 3D radiological signs within the 3D image, determining a set of 2D candidate particles corresponding to projections of the presumed 3D radiological signs, assigning, through a fuzzy logic description, to the 2D candidate particles a degree of membership in 2D membership classes of a set of membership classes, each membership class being relative to a type of radiological sign, considering a 2D fuzzy particle being formed by the set of the 2D candidate particles and by their respective degrees of membership in a class, making an aggregate of the 2D fuzzy particles to obtain 3D fuzzy particles in a digital volume, and determining a degree of confidence for each 3D radiological sign from the 3D fuzzy particles.
摘要翻译：一种放射学装置中的图像处理方法包括：从一组放射线照相投影图像重建身体的3D图像，将假定为代表3D图像内的3D放射学符号的定位结构，确定与投影对应的一组2D候选粒子通过模糊逻辑描述，将二维候选粒子分配给一组隶属类的二维隶属类中的隶属度，每个隶属类别相对于放射学符号的类型，考虑2D 模糊粒子由2D候选粒子的集合和其各自的隶属度形成，使2D模糊粒子的聚集获得数字体积中的3D模糊粒子，并且确定每个3D的置信度放射学符号从3D模糊粒子。

28. 发明申请

US20110019891A1 MEDICAL IMAGING PROCESS FOR TRIPLE-ENERGY MODELING, AND DEVICE FOR IMPLEMENTING SUCH A PROCESS 审中-公开
标题翻译：用于三重能量建模的医学成像过程，以及用于实现这一过程的设备
公开(公告)号：US20110019891A1
公开(公告)日：2011-01-27
申请号：US12839436
申请日：2010-07-20
申请人： Sylvie Puong , Serge Muller , Razvan Iordache , Xavíer Bouchevreau
发明人： Sylvie Puong , Serge Muller , Razvan Iordache , Xavíer Bouchevreau
IPC分类号： G06K9/00
CPC分类号： A61B6/482 , A61B6/405 , A61B6/502 , A61B6/542
摘要： A method for X-ray imaging of a body using an imaging device comprising an image sensor and an X-ray emitter which operates at different emission spectra, wherein the method includes: acquiring a first image resulting from the passage through the body of X-rays emitted by the X-ray emitter with a first emission spectrum; calculating characteristics of the body on the basis of the first image, and calculating a second and a third emission spectrum based on the characteristics of the body, wherein the first, second and third emission spectra are distinct from one another; acquiring a second and third image resulting from the passage through the body of X-rays emitted by the X-ray emitter with the second and third emission spectrum respectively; and modeling the body by generating thickness charts for different materials comprising the body on the basis of the three images.
摘要翻译：一种用于使用包括图像传感器和在不同发射光谱下操作的X射线发射器的成像装置对人体进行X射线成像的方法，其中所述方法包括：获取由穿过X射线体的通道产生的第一图像，由X射线发射器发射的具有第一发射光谱的射线; 基于第一图像计算身体的特征，以及基于身体的特性计算第二和第三发射光谱，其中第一，第二和第三发射光谱彼此不同; 获取由分别具有第二和第三发射光谱的由X射线发射器发射的X射线体穿过的第二和第三图像; 并通过基于三个图像生成包括身体的不同材料的厚度图来对身体进行建模。

29. 发明授权

US07853064B2 Method for the processing of radiological images in tomosynthesis for a detection of radiological signs 有权
标题翻译：用于放射学检查放射学图像处理的方法
公开(公告)号：US07853064B2
公开(公告)日：2010-12-14
申请号：US11756471
申请日：2007-05-31
申请人： Sylvain Bernard , Serge Muller , Henri Souchay , Gero Peters , Razvan Iordache
发明人： Sylvain Bernard , Serge Muller , Henri Souchay , Gero Peters , Razvan Iordache
IPC分类号： G06K9/00 , A61B6/00 , A61B6/04
CPC分类号： G06T11/008 , G06T7/0012 , G06T2207/10072 , G06T2207/10116 , G06T2207/20064 , G06T2207/30068 , G06T2211/436
摘要： In an image-processing method for the detection of radiological signs in series of 3D data, an algorithm is used to detect radiological signs in a digital volume according to their contrasts. This algorithm is applied to reconstructed slices or directly to the series of projections. This algorithm is made by means of linear differential filters for signal analysis. It is used to color or enhance the intensity of the detected radiological signals according to the degree of malignancy.
摘要翻译：在用于检测3D数据的放射性符号的图像处理方法中，使用算法根据其对比度来检测数字体积中的放射学符号。该算法应用于重建的切片或直接应用于一系列投影。该算法通过线性差分滤波器进行信号分析。用于根据恶性程度对检测到的放射信号的强度进行着色或增强。

30. 发明授权

US07248727B2 Method and apparatus for displaying images of an object 失效
标题翻译：用于显示对象的图像的方法和装置
公开(公告)号：US07248727B2
公开(公告)日：2007-07-24
申请号：US10153326
申请日：2002-05-22
申请人： Elisabeth Soubelet , Serge Muller , Andreas Rick
发明人： Elisabeth Soubelet , Serge Muller , Andreas Rick
IPC分类号： G06K9/00
CPC分类号： G06T5/40 , G06T5/007 , G06T2207/30068
摘要： A region of interest is selected in an input image, such as a digital or analog image form a mammography apparatus. Display parameters for the input image or a part thereof are determined as a function of the region of interest. The image or a part thereof is displayed using the determined parameters. Choosing display parameters as a function of the region of interest optimizes the display of the possible region of interest without any adjustment by the operator.
摘要翻译：在诸如数字或模拟图像的输入图像中选择感兴趣的区域，形成乳房X线照相术装置。输入图像或其一部分的显示参数被确定为感兴趣区域的函数。使用确定的参数来显示图像或其一部分。选择显示参数作为感兴趣区域的函数，可以优化显示可能的感兴趣区域，而无需操作人员进行任何调整。

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