专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

21. 再颁专利

USRE39094E1 Pyropheophorbides and their use in photodynamic therapy 有权
标题翻译：偏焦异构体及其在光动力疗法中的应用
公开(公告)号：USRE39094E1
公开(公告)日：2006-05-09
申请号：US10384895
申请日：2003-03-07
申请人： Ravindra K. Pandey , Thomas J. Dougherty
发明人： Ravindra K. Pandey , Thomas J. Dougherty
IPC分类号： A61K31/409 , C07D487/22
CPC分类号： A61K51/0485 , A61K41/0071 , A61K2123/00 , C07D487/22 , C07D519/00
摘要： Pyropheophorbide compounds are injected into a host and accumulate in tumor tissue to a higher degree than surrounding normal tissues. When the pyropheophorbide compounds are exposed to a particular wavelength of light the compounds become cytotoxic and destroy the tumor or diseased tissue without causing irreversible normal tissue damage. The pyropheophorbide compounds have shown improved results as compared to drugs currently used in photodynamic therapy. Further, they absorb light further in the red, optimizing tissue penetration mad are retained in the skin for short time periods relative to other drugs used in photodynamic therapy.
摘要翻译：将焦磷偏磷酸酯化合物注射到宿主中并在肿瘤组织中积聚到比周围正常组织更高的程度。当焦偏磷酸酯化合物暴露于特定波长的光时，化合物变成细胞毒性并破坏肿瘤或患病组织而不引起不可逆的正常组织损伤。与目前在光动力疗法中使用的药物相比，焦偏镁离子化合物显示出改善的结果。此外，它们进一步吸收红色的光线，相对于光动力治疗中使用的其他药物，优化组织穿透时间短于皮肤的时间。

22. 发明授权

US06727708B1 Battery monitoring system 有权
标题翻译：电池监控系统
公开(公告)号：US06727708B1
公开(公告)日：2004-04-27
申请号：US10313983
申请日：2002-12-06
申请人： Thomas J. Dougherty , William J. Wruck , Ronald C. Miles , Deeyu C. Chen , Michael L. Thompson
发明人： Thomas J. Dougherty , William J. Wruck , Ronald C. Miles , Deeyu C. Chen , Michael L. Thompson
IPC分类号： H02J700
CPC分类号： H01M10/4257 , B60L11/14 , B60L11/1857 , B60L11/1861 , B60L2240/545 , B60L2240/547 , B60L2240/549 , B60L2240/80 , G01R31/36 , H01M10/44 , H02J7/0047 , Y02T10/70 , Y02T10/7005 , Y02T10/7044 , Y02T10/705 , Y02T10/7077
摘要： A battery monitoring system is disclosed. The system comprises a means for acquiring a value representative of a first period of time during which the battery will deliver a sufficient amount of power. The system also comprises a means for measuring a set of parameters comprising a voltage of the battery and a temperature of the battery during a second period of time. The system also comprises a means for predicting whether the battery will deliver the sufficient amount of power during a third period of time less than the first period of time. An output signal is provided if the means for predicting determines that the battery will deliver the sufficient amount of power during the third period of time. A system for determining whether a battery for a vehicle will deliver a sufficient amount of power for a sufficient amount of time is also disclosed.
摘要翻译：公开了一种电池监视系统。该系统包括用于获取代表电池将传送足够量的电力的第一时间段的值的装置。该系统还包括用于在第二时间段内测量包括电池的电压和电池的温度的一组参数的装置。该系统还包括用于预测在比第一时间段少的第三时间段内电池是否将传递足够量的电力的装置。如果用于预测的装置确定电池将在第三时间段期间输送足够量的电力，则提供输出信号。还公开了一种用于确定车辆的电池是否将足够的时间量传递足够的电力的系统。

23. 发明授权

US06461758B1 Battery with vent cap assembly 有权
标题翻译：电池带通风盖组件
公开(公告)号：US06461758B1
公开(公告)日：2002-10-08
申请号：US09622737
申请日：2000-10-20
申请人： Matthias Geibl , Thomas J. Dougherty , Gerald D. Slayton , Mark S. Inkmann , Guy L. Pfeifer , Gerald A. Cummins , Edward C. Frelka , Edward N. Mrotek , Helmuth Faust , Arch A. Pope , David J. Novak , William J. Ross , Bradley R. Niemuth , Ronald F. Kirby
发明人： Matthias Geibl , Thomas J. Dougherty , Gerald D. Slayton , Mark S. Inkmann , Guy L. Pfeifer , Gerald A. Cummins , Edward C. Frelka , Edward N. Mrotek , Helmuth Faust , Arch A. Pope , David J. Novak , William J. Ross , Bradley R. Niemuth , Ronald F. Kirby
IPC分类号： H01M212
CPC分类号： H01M2/1217 , H01M2/1205 , H01M2/36 , H01M10/06 , H01M10/42
摘要： An improved vent cap system for use in an electrochemical battery is provided which includes a ring flange for forming a ring seal between the vent cap assembly and the fill tube. When the vent cap assembly is positioned in the battery housing, the ring flange and the fill tube deform to create a seal therebetween to provide a fluid tight seal.
摘要翻译：提供了一种用于电化学电池的改进的通气帽系统，其包括用于在通气盖组件和填充管之间形成环形密封件的环形凸缘。当通气盖组件定位在电池壳体中时，环形凸缘和填充管变形以在其间形成密封以提供流体密封。

24. 发明授权

US6164541A Methods and systems for providing human/computer interfaces 有权
公开(公告)号：US6164541A
公开(公告)日：2000-12-26
申请号：US371317
申请日：1999-08-10
申请人： Thomas J. Dougherty , S. Joy Mountford , Jesse L. Dorogusker , James H. Boyden , Philip A. van Allen , Daniel E. Cummings , Brygg A. Ullmer
发明人： Thomas J. Dougherty , S. Joy Mountford , Jesse L. Dorogusker , James H. Boyden , Philip A. van Allen , Daniel E. Cummings , Brygg A. Ullmer
IPC分类号： G06K7/12 , G06K19/06 , G06K7/10 , G06F17/00
CPC分类号： G06K7/1443 , G06K7/12 , G06K19/06009 , G06K19/06037
摘要： The present invention teaches a variety of methods and systems for providing computer/human interfaces. According to one method, the user interfaces with an electronic device such as a computer system by engaging a sensor with desired regions of an encoded physical medium. The encoded physical medium is preferably chosen to provide intuitive meaning to the user, and is thus an improved metaphor for interfacing with the computer system. Suitable examples of the encoded physical medium include a data-linked book, magazine, globe, or article of clothing. Some or all of the selected regions have had certain information encoded therein, information suitable for interfacing and controlling the computer system. When the user engages the sensor with a region having certain encoded information, the certain encoded information is interpreted and an appropriate action taken. For example, the sensor or the computer system may provide suitable feedback to the user. The encoded physical medium may have text and/or graphic illustrations that draw the user in or provide meaningful clues or instructions perhaps related to the encoded information. The sensor may have at least one identification number (ID) providing information such as user identity, sensor type, access type, or language type. The sensor can transmit the certain decoded information together with the at least one ID to the computer system.

25. 发明授权

US5952366A Alkyl ether analogs of chlorins having an N-substituted imide ring 失效
标题翻译：具有N-取代的酰亚胺环的二氢卟酚的烷基醚类似物
公开(公告)号：US5952366A
公开(公告)日：1999-09-14
申请号：US102394
申请日：1998-06-22
申请人： Ravindra K. Pandey , William R. Potter , Thomas J. Dougherty
发明人： Ravindra K. Pandey , William R. Potter , Thomas J. Dougherty
IPC分类号： C07D487/22 , A61K31/409 , A61K41/00 , A61P35/00 , C07D519/00 , A61K31/40
CPC分类号： C07D519/00 , A61K41/0071
摘要： Compounds having the generic formula: ##STR1## where R.sup.1, R.sup.2 and R.sup.3 are independently alkyl of 3 through about 10 carbon atoms; provided that, R.sup.1 and R.sup.2 together contain at least six carbon atoms. The compounds have utility in photodynamic therapy in treatment of tumors and other diseases. The invention includes a method of treatment by contacting a tumor with the compound and then exposing the tumor to light.
摘要翻译：具有以下通式的化合物：其中R 1，R 2和R 3独立地为3至约10个碳原子的烷基; 条件是R 1和R 2一起含有至少6个碳原子。该化合物在光动力疗法中可用于治疗肿瘤和其他疾病。本发明包括通过使肿瘤与化合物接触然后将肿瘤暴露于光来治疗的方法。

26. 发明授权

US5864035A Synthesis of isoimide of chlorins and bacteriochlorins and their use for diagnosis and treatment of cancer 失效
标题翻译：二氢卟酚和细菌二氢卟酚的异构酰亚胺的合成及其在癌症诊断和治疗中的应用
公开(公告)号：US5864035A
公开(公告)日：1999-01-26
申请号：US812029
申请日：1997-03-06
申请人： Ravindra K. Pandey , Andrei N. Kozyrev , Thomas J. Dougherty
发明人： Ravindra K. Pandey , Andrei N. Kozyrev , Thomas J. Dougherty
IPC分类号： A61K41/00 , C07D471/22 , C07D491/22 , C07D487/22
CPC分类号： C07D471/22 , A61K41/0071 , C07D491/22
摘要： Compounds having utility as light absorbing compounds, especially in the area of photodynamic therapy. Such compounds have the formula: ##STR1## where z is .dbd.O or NR.sub.14 ; R.sub.14 is alkyl or substituted alkyl; R.sub.1 is an amino acid group, a polyamine group, a polyether group or OR.sub.13 where R.sub.13 is alkyl; R.sub.4 through R.sub.11 are --H, --OH alkyl, alkoxy, alkenyl, alkylene, aryl, or aryloxy, or a carbonyl containing group, wherein carbon containing groups may be substituted with carbonyl, hydroxy, phosphoro, carboxy, halo, sulfo, amino and ether substituents, provided that; R.sub.4 may be taken together with R.sub.7 to form .dbd.O; R.sub.8 may be taken together with R.sub.9 to form .dbd.O; R.sub.10 may be taken together with R.sub.11 to form .dbd.O; and R.sub.4 and R.sub.7 may together form a chemical bond and R.sub.8 and R.sub.11 may together form a chemical bond; and R.sub.12 is hydrogen or lower alkyl; provided that if one z is O, the other z is --NR.sub.14.
摘要翻译：具有作为光吸收化合物用途的化合物，特别是在光动力疗法领域。这些化合物具有下式：其中z为= O或NR14; R14是烷基或取代的烷基; R1是氨基酸基团，多胺基团，聚醚基团或OR13，其中R13是烷基; R4至R11是-H，-OH烷基，烷氧基，烯基，亚烷基，芳基或芳氧基或含羰基，其中含碳基团可以被羰基，羟基，磷酰基，羧基，卤素，磺基，氨基和醚取代基，条件是 R4可以与R7一起形成= O; R8可以与R9一起形成= O; R10可以与R11一起形成= O; 并且R 4和R 7可以一起形成化学键，并且R 8和R 11可以一起形成化学键; 和R 12是氢或低级烷基; 条件是如果一个z是O，另一个Z是-NR 14。

27. 发明授权

US5688612A Battery cover and vent cap interface seal 失效
标题翻译：电池盖和通风盖接口密封
公开(公告)号：US5688612A
公开(公告)日：1997-11-18
申请号：US739238
申请日：1996-10-29
申请人： Edward N. Mrotek , Thomas J. Dougherty , Gerald A. Cummins , Dean R. Walsten
发明人： Edward N. Mrotek , Thomas J. Dougherty , Gerald A. Cummins , Dean R. Walsten
IPC分类号： H01M2/12
CPC分类号： H01M2/1217
摘要： A battery cover and vent cap interface seal for electrical storage batteries is disposed between the vent opening in the battery cover and the vent cap to establish a fluid-fight seal. In a first embodiment an annular sealing member is provided in each vent opening in the battery cover. The sealing members extend slightly beyond the inner periphery of the vent opening in the cover and are compressed by the vent cap plugs as the vent cap is installed. In a second embodiment annular sealing members are provided around each plug on the vent cap. The sealing members extend slightly beyond the outer periphery of the plugs and are compressed as the vent cap is installed on the battery cover. The sealing members are made of a resilient material that deforms more easily than the materials used for the battery cover and vent cap.
摘要翻译：用于蓄电池的电池盖和通气帽接口密封件设置在电池盖的通风口和通气盖之间，以建立流体密封。在第一实施例中，环形密封件设置在电池盖中的每个通气口中。密封构件稍微超过盖子中的通风口的内周边延伸，并且当通风盖被安装时被密封件压缩。在第二实施例中，环形密封构件设置在通气盖上的每个塞子周围。密封构件稍微延伸超过塞子的外周边，并且当通气盖安装在电池盖上时被压缩。密封构件由弹性材料制成，其比用于电池盖和通气盖的材料更容易变形。

28. 发明授权

US5204610A Long lived dual battery with automatic latching switch 失效
标题翻译：长寿命双电池带自动闭锁开关
公开(公告)号：US5204610A
公开(公告)日：1993-04-20
申请号：US656772
申请日：1991-02-15
申请人： John R. Pierson , Thomas J. Dougherty , Ronald C. Klassen
发明人： John R. Pierson , Thomas J. Dougherty , Ronald C. Klassen
IPC分类号： H02J9/06
CPC分类号： H02J9/061 , Y10T307/625
摘要： A latching automatic dual battery switch employs a first comparator to determine that a condition requiring engagement of a secondary battery exists. For example, a primary battery voltage is below a predetermined threshold, current drawn from the primary battery exceeds a predetermined threshold or ambient temperature is below a predetermined threshold. Engagement of an ignition switch is detected and used to clock the output of the comparator to a trigger circuit. The trigger circuit activates the triggerable switch on the leading edge of a signal generated by the detector circuit to connect a secondary battery or power source in parallel with the primary power source. The trigger circuit is leading edge activated so that conditions immediately prior to engagement of the ignition switch determine if the secondary battery is engaged. This avoids engaging the secondary battery as a result of a load surge dragging down the voltage after activation of an ignition switch. In addition, when the ignition switch is released, a timing circuit is engaged to limit the additional time during which the secondary battery is switched in the circuit. The automatic engagement of the secondary battery eliminates the need for manually switching to an emergency backup and manually disengaging the emergency backup after a vehicle is started.
摘要翻译：闩锁自动双电池开关采用第一比较器来确定需要二次电池接合的状况。例如，一次电池电压低于预定阈值，从初级电池抽出的电流超过预定阈值或环境温度低于预定阈值。检测点火开关的接合，并将其用于将比较器的输出定时到触发电路。触发电路激活由检测器电路产生的信号的前沿上的可触发开关，以将二次电池或电源与主电源并联连接。触发电路处于前沿被激活，使得紧接在点火开关接合之前的状态确定二次电池是否接合。这避免了由于在启动点火开关之后负载浪涌向下拖动电压而使二次电池接合。此外，当点火开关被释放时，接合定时电路以限制二次电池在电路中切换的附加时间。二次电池的自动接合消除了在车辆启动之后手动切换到紧急备用和手动分离紧急备用的需要。

29. 发明授权

US5002962A Photosensitizing agents 失效
标题翻译：光敏剂
公开(公告)号：US5002962A
公开(公告)日：1991-03-26
申请号：US221804
申请日：1988-07-20
申请人： Ravindra K. Pandey , Thomas J. Dougherty
发明人： Ravindra K. Pandey , Thomas J. Dougherty
IPC分类号： A61K31/40 , A61K41/00 , A61K51/04 , A61P31/12 , A61P35/00 , C07D487/22 , C07D519/00
CPC分类号： C07D487/22 , A61K41/0071 , A61K51/0485 , C07D519/00 , A61K2123/00
摘要： New classes of photosensitizing compounds useful in photodynamic therapy are disclosed. These compounds are simplified dimers and polymers of monohydroxy deuteroporphyrins, hydrophobic ethers of these monomers, and red light-absorbing derivatives of methyl pheophorbide-a.
摘要翻译：公开了可用于光动力学治疗的新类型的光敏化合物。这些化合物是简单的二聚体和单羟基氘卟啉的聚合物，这些单体的疏水性醚，以及脱镁叶绿酸甲酯的红光吸收衍生物。

30. 发明授权

US10044074B2 Battery power source control and current detection systems and methods 有权
公开(公告)号：US10044074B2
公开(公告)日：2018-08-07
申请号：US13420464
申请日：2012-03-14
申请人： Craig W. Rigby , Thomas J. Dougherty , Chih Yu Chen
发明人： Craig W. Rigby , Thomas J. Dougherty , Chih Yu Chen
IPC分类号： H02J7/00 , H01M10/48 , H01M10/633
摘要： Provided battery systems include a plurality of battery electronic control units, each associated with a battery pack of a plurality of battery packs. Each battery electronic control unit is adapted to acquire analog current measurements of the associated battery pack and to convert the acquired analog current measurements to a digital value such that the plurality of battery electronic control units produce a plurality of digital values. The system may sum the digital values, or may process pulse-width modulated signals, analog signals and so forth. A battery system electronic control unit is adapted to receive and monitor the plurality of digital values and to determine a total battery system current value based on the received plurality of digital values.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式