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21. 发明申请

US20110142201A1 MULTI-VIEW IMAGING SYSTEM AND METHOD 审中-公开
标题翻译：多视图成像系统和方法
公开(公告)号：US20110142201A1
公开(公告)日：2011-06-16
申请号：US12638471
申请日：2009-12-15
申请人： Jeffrey Wayne Eberhard , Bernhard Erich Hermann Claus , Colin Richard Wilson , Kedar Bhalchandra Khare
发明人： Jeffrey Wayne Eberhard , Bernhard Erich Hermann Claus , Colin Richard Wilson , Kedar Bhalchandra Khare
IPC分类号： G01N23/04
CPC分类号： G01V5/0008
摘要： A multi-view imaging system and method is disclosed. The system comprises: multiple X-ray sources emitting X-rays in a fan-shaped beam each having a first and a second beam edge defining a fan beam angle located in a predetermined configuration around an imaging volume; a system controller configured to operate the X-ray sources; detectors, to detect X-rays and configured to generate signals in response to the detected X-rays, wherein each of the plurality of X-ray sources are configured to emit X-rays to one or more detectors, further wherein the X-ray source and two end points of a corresponding detector define a fan beam plane, further wherein a line extending from the X-ray source within the fan beam plane and through the imaging volume defines a projection direction, wherein adjacent projection directions define an angular spacing; an object conveyance device configured for transporting an object along a path of travel through the imaging volume between the X-ray sources and the detectors; and a detector interface configured to acquire the signals from the detectors, wherein the predetermined configuration is defined wherein either: the projection directions when viewed along a longitudinal axis of the image system surround the imaging volume by an angular range of about 180 degrees; or the projection directions when viewed along a longitudinal axis of the image system surround the imaging volume by an angular range of about 180°−180/Q, wherein Q is a quantity of the projection directions.
摘要翻译：公开了一种多视点成像系统和方法。该系统包括：多个X射线源在扇形光束中发射X射线，每个X射线源具有限定围绕成像体积的预定构型的扇形束角度的第一和第二光束边缘; 被配置为操作所述X射线源的系统控制器; 检测器，用于检测X射线并被配置为响应于检测到的X射线产生信号，其中多个X射线源中的每一个被配置为向一个或多个检测器发射X射线，其中X射线相应检测器的源极和两个端点限定了扇形光束平面，其中，从扇形光束平面内的X射线源延伸并穿过成像体积的线限定了投射方向，其中相邻的投射方向限定角度间隔; 物体输送装置，被配置为沿着X射线源和检测器之间的成像体积沿行进路径传送物体; 以及检测器接口，被配置为从所述检测器获取信号，其中限定所述预定配置，其中：沿着所述图像系统的纵轴观察的投影方向围绕所述成像体积约180度的角度范围; 或者沿着图像系统的纵轴观察时的投影方向围绕成像体积约180°-180 / Q的角度范围，其中Q是投影方向的量。

22. 发明授权

US07653263B2 Method and system for volumetric comparative image analysis and diagnosis 有权
标题翻译：体积比较图像分析与诊断方法与系统
公开(公告)号：US07653263B2
公开(公告)日：2010-01-26
申请号：US11172655
申请日：2005-06-30
申请人： Frederick Wilson Wheeler , Bernhard Erich Hermann Claus , John Patrick Kaufhold , Jeffrey Wayne Eberhard , Mark Lewis Grabb , Cynthia Elizabeth Landberg
发明人： Frederick Wilson Wheeler , Bernhard Erich Hermann Claus , John Patrick Kaufhold , Jeffrey Wayne Eberhard , Mark Lewis Grabb , Cynthia Elizabeth Landberg
IPC分类号： G06K9/52 , G06K9/00
CPC分类号： G06T7/0012 , G06T7/001 , G06T7/38 , G06T2207/30004
摘要： A technique is provided for comparative image analysis and/or change detection using computer assisted detection and/or diagnosis (CAD) algorithms. The technique includes registering two or more images, comparing the images with one another to generate a change map, and detecting anomalies in the images based on the change map.
摘要翻译：提供了一种用于使用计算机辅助检测和/或诊断（CAD）算法的比较图像分析和/或变化检测的技术。该技术包括登记两个或多个图像，将图像彼此进行比较以生成改变图，并且基于变化图检测图像中的异常。

23. 发明申请

US20080144767A1 Method and System for Multi-Energy Tomosynthesis 有权
标题翻译：多能量合成的方法与系统
公开(公告)号：US20080144767A1
公开(公告)日：2008-06-19
申请号：US12037730
申请日：2008-02-26
申请人： Jeffrey Wayne Eberhard , John Patrick Kaufhold , Bernhard Erich Hermann Claus , Kadri Nizar Jabri , Gopal B. Avinash , John Michael Sabol
发明人： Jeffrey Wayne Eberhard , John Patrick Kaufhold , Bernhard Erich Hermann Claus , Kadri Nizar Jabri , Gopal B. Avinash , John Michael Sabol
IPC分类号： A61B6/00
CPC分类号： A61B6/025 , A61B6/4035 , A61B6/4241 , A61B6/4291 , A61B6/482 , A61B6/5288 , A61B6/541
摘要： Briefly in accordance with one embodiment, the present technique provides a multi-energy tomosynthesis imaging system. The system includes an X-ray source configured to emit X-rays from multiple locations within a limited angular range relative to an imaging volume. The imaging system also includes a digital detector with an array of detector elements to generate images in response to the emitted X-rays. The imaging system further includes a detector acquisition circuitry to acquire the images from the digital detector. The imaging system may also include a processing circuitry configured to decompose plurality of images based on energy characteristics and to reconstruct the plurality of images to generate a three-dimensional multi-energy tomosynthesis image.
摘要翻译：简而言之，根据一个实施例，本技术提供了一种多能量断层合成成像系统。该系统包括被配置为相对于成像体积在有限的角度范围内从多个位置发射X射线的X射线源。成像系统还包括具有检测器元件阵列的数字检测器，以响应于发射的X射线产生图像。成像系统还包括用于从数字检测器获取图像的检测器采集电路。成像系统还可以包括处理电路，其被配置为基于能量特性分解多个图像，并且重建多个图像以生成三维多能量断层合成图像。

24. 发明授权

US06940943B2 Continuous scan tomosynthesis system and method 有权
标题翻译：连续扫描断层合成系统及方法
公开(公告)号：US06940943B2
公开(公告)日：2005-09-06
申请号：US10265489
申请日：2002-10-07
申请人： Bernhard Erich Hermann Claus , Ajay Kapur , Jeffrey Wayne Eberhard
发明人： Bernhard Erich Hermann Claus , Ajay Kapur , Jeffrey Wayne Eberhard
IPC分类号： A61B6/02 , G01N23/04 , H05G1/60
CPC分类号： A61B6/025 , A61B6/4208 , A61B6/4452 , A61B6/588 , G01N23/04
摘要： An imaging system for performing tomosynthesis on a region of an object comprises an x-ray source, motion controller, an x-ray detector and a processing unit. The x-ray source is positioned at a predetermined distance from the object and continuously moves along a path relative to the object at a plurality of predetermined locations. The x-ray source transmits x-ray radiation through the region of the object. The motion controller is coupled to the x-ray source and continuously moves the x-ray source along the path relative to the object. The x-ray source minimizes vibration in the imaging system due to continuous movement. The x-ray detector is positioned at a predetermined distance from the x-ray source and detects the x-ray radiation transmitted through the region of the object, thus acquiring x-ray image data representative of the region of the object. The processing unit is coupled to the x-ray detector for processing the x-ray image data into at least one tomosynthesis image of the region of the object.
摘要翻译：用于在对象区域执行断层合成的成像系统包括x射线源，运动控制器，x射线检测器和处理单元。 x射线源定位在距物体预定距离处，并且在多个预定位置处沿相对于物体的路径连续移动。 x射线源通过物体的区域透射x射线辐射。运动控制器耦合到x射线源并且沿着相对于物体的路径连续地移动x射线源。 x射线源由于连续运动而使成像系统中的振动最小化。 x射线检测器定位在距离x射线源预定的距离处，并检测透过物体区域的X射线辐射，从而获取表示物体区域的X射线图像数据。处理单元耦合到X射线检测器，用于将X射线图像数据处理成对象区域的至少一个断层合成图像。

25. 发明授权

US06751285B2 Dose management system for mammographic tomosynthesis 失效
标题翻译：用于乳房X线断层合成术的剂量管理系统
公开(公告)号：US06751285B2
公开(公告)日：2004-06-15
申请号：US09990114
申请日：2001-11-21
申请人： Jeffrey Wayne Eberhard , Bernhard Erich Hermann Claus , Beale Opsahl-Ong , Ralph Allen Hewes
发明人： Jeffrey Wayne Eberhard , Bernhard Erich Hermann Claus , Beale Opsahl-Ong , Ralph Allen Hewes
IPC分类号： A61B604
CPC分类号： A61B6/502 , A61B5/1075 , A61B6/544
摘要： A method for acquiring a plurality of images of an object of interest using a tomosynthesis imaging system. The method includes determining a thickness of an object of interest, and adjusting at least one parameter of an image acquisition process based on the determined thickness.
摘要翻译：一种使用断层摄影成像系统获取感兴趣对象的多个图像的方法。该方法包括确定感兴趣对象的厚度，并且基于所确定的厚度来调整图像获取过程的至少一个参数。

26. 发明申请

US20120020448A1 SYSTEM AND METHOD FOR RECONSTRUCTION OF X-RAY IMAGES 有权
标题翻译：用于重建X射线图像的系统和方法
公开(公告)号：US20120020448A1
公开(公告)日：2012-01-26
申请号：US12841815
申请日：2010-07-22
申请人： Kedar Bhalchandra Khare , Jeffrey Wayne Eberhard , Bernhard Erich Hermann Claus
发明人： Kedar Bhalchandra Khare , Jeffrey Wayne Eberhard , Bernhard Erich Hermann Claus
IPC分类号： H05G1/60
CPC分类号： G06T11/006 , G06T2211/424 , G06T2211/436
摘要： Systems and method for reconstruction of x-ray images are provided. One method includes acquiring a plurality of image views using an x-ray imaging system, the plurality of image views defining a limited tomographic dataset. The method also includes performing three-dimensional (3D) image reconstruction using the plurality of image views in an iterative reconstruction, wherein the iterative reconstruction includes forming a linear combination based on a plurality of previous iteration results. The method further includes displaying an image based on the image reconstruction, wherein the image includes clinically relevant high-frequency detail information.
摘要翻译：提供了重建X射线图像的系统和方法。一种方法包括使用X射线成像系统获取多个图像视图，所述多个图像视图限定有限层析成像数据集。该方法还包括在迭代重建中使用多个图像视图执行三维（3D）图像重建，其中迭代重建包括基于多个先前的迭代结果形成线性组合。该方法还包括基于图像重建来显示图像，其中图像包括临床相关的高频细节信息。

27. 发明授权

US07742796B2 Breast immobilization device and method of imaging the breast 有权
标题翻译：乳房固定装置及乳房成像方法
公开(公告)号：US07742796B2
公开(公告)日：2010-06-22
申请号：US11257901
申请日：2005-10-25
申请人： Jeffrey Wayne Eberhard , Abdulrahman Abdallah Al-khalidy , Cynthia Elizabeth Landberg , Bernhard Erich Hermann Claus , Reinhold Franz Wirth
发明人： Jeffrey Wayne Eberhard , Abdulrahman Abdallah Al-khalidy , Cynthia Elizabeth Landberg , Bernhard Erich Hermann Claus , Reinhold Franz Wirth
IPC分类号： A61B5/05 , A61B6/00 , A61B6/04
CPC分类号： A61B8/0825 , A61B6/502 , A61B6/5247 , A61B8/42 , A61B8/4281 , A61B8/4416 , A61B8/483
摘要： A method for imaging a breast is provided. The method includes positioning a breast within a breast holder including a flexible membrane and creating at least a partial vacuum within the flexible membrane. A method of upgrading a mammography system and various configurations of breast holders are also provided.
摘要翻译：提供了一种用于乳房成像的方法。该方法包括将乳房定位在包括柔性膜的乳房保持器内并且在柔性膜内产生至少部分真空。还提供了升级乳房X线照相系统和乳房保持器的各种构造的方法。

28. 发明申请

US20080135772A1 METHOD AND SYSTEM FOR SPECIAL NUCLEAR MATERIAL DETECTION 审中-公开
标题翻译：特殊核材料检测方法与系统
公开(公告)号：US20080135772A1
公开(公告)日：2008-06-12
申请号：US11608095
申请日：2006-12-07
申请人： Bernhard Erich Hermann Claus , Jeffrey Wayne Eberhard
发明人： Bernhard Erich Hermann Claus , Jeffrey Wayne Eberhard
IPC分类号： G01V5/00
CPC分类号： G01V5/0091
摘要： A method of analyzing a container for presence of special nuclear materials (SNM) is disclosed. The method includes obtaining information regarding at least one of the container and contents therein, automatically selecting an operational parameter in response to the information; and, performing a screening of the container according to the selected operational parameter. The screening includes irradiating the container with an energetic beam comprising at least one of fast neutrons and high-energy photons; detecting energy emitted in response to the irradiating; and analyzing the detected energy for a presence of SNM.
摘要翻译：公开了一种分析特定核材料（SNM）的容器的方法。所述方法包括获取关于所述容器和其中的内容中的至少一个的信息，响应于所述信息自动选择操作参数; 以及根据所选择的操作参数对容器进行筛选。筛选包括用包含快中子和高能光子中的至少一种的能量束照射容器; 检测响应于照射而发射的能量; 并分析检测到的能量以存在SNM。

29. 发明申请

US20070092059A1 Breast immobilization device and method of imaging the breast 有权
标题翻译：乳房固定装置及乳房成像方法
公开(公告)号：US20070092059A1
公开(公告)日：2007-04-26
申请号：US11257901
申请日：2005-10-25
申请人： Jeffrey Wayne Eberhard , Abdulrahman Abdallah Al-khalidy , Cynthia Elizabeth Landberg , Bernhard Erich Hermann Claus , Reinhold Franz Wirth
发明人： Jeffrey Wayne Eberhard , Abdulrahman Abdallah Al-khalidy , Cynthia Elizabeth Landberg , Bernhard Erich Hermann Claus , Reinhold Franz Wirth
IPC分类号： A61B6/04 , A61B8/00
CPC分类号： A61B8/0825 , A61B6/502 , A61B6/5247 , A61B8/42 , A61B8/4281 , A61B8/4416 , A61B8/483
摘要： A method for imaging a breast is provided. The method includes positioning a breast within a breast holder including a flexible membrane and creating at least a partial vacuum within the flexible membrane. A method of upgrading a mammography system and various configurations of breast holders are also provided.
摘要翻译：提供了一种用于乳房成像的方法。该方法包括将乳房定位在包括柔性膜的乳房保持器内并且在柔性膜内产生至少部分真空。还提供了升级乳房X线照相系统和乳房保持器的各种构造的方法。

30. 发明授权

US07142633B2 Enhanced X-ray imaging system and method 有权
标题翻译：增强X射线成像系统及方法
公开(公告)号：US07142633B2
公开(公告)日：2006-11-28
申请号：US10813759
申请日：2004-03-31
申请人： Jeffrey Wayne Eberhard , Bernhard Erich Hermann Claus , Cynthia Landberg
发明人： Jeffrey Wayne Eberhard , Bernhard Erich Hermann Claus , Cynthia Landberg
IPC分类号： G01N23/04
CPC分类号： A61B6/502 , A61B6/027 , A61B6/4007 , A61B6/4035 , A61B6/482 , A61B6/584 , G06F19/00 , Y10S378/901
摘要： Techniques are provided for generating three-dimensional images, such as may be used in mammography. In accordance with these techniques, projection images of an object of interest are acquired from different locations, such as by moving an X-ray source along an arbitrary imaging trajectory between emissions or by individually activating different X-ray sources located at different locations relative to the object of interest. The projection images may be reconstructed to generate a three-dimensional dataset representative of the object from which one or more volumes may be selected for visualization and display. Additional processing steps may occur throughout the image chain, such as for pre-processing the projection images or post-processing the three-dimensional dataset.
摘要翻译：提供了用于产生三维图像的技术，例如可用于乳房X线照相术。根据这些技术，例如通过沿着发射之间的任意成像轨迹移动X射线源或通过单独激活位于相对于不同位置的不同位置处的不同X射线源，从不同位置获取感兴趣对象的投影图像感兴趣的对象。可以重建投影图像以生成代表对象的三维数据集，从该对象可以选择一个或多个卷来进行可视化和显示。在整个图像链中可能发生附加处理步骤，例如用于预处理投影图像或对3D维数据集进行后处理。

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