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21. 发明专利

ES2549116T3 Uso de composiciones que contienen carnosol y/o rosmanol 未知
公开(公告)号：ES2549116T3
公开(公告)日：2015-10-23
申请号：ES07856230
申请日：2007-11-22
申请人： DSM IP ASSETS BV , NESTEC SA
发明人： FOWLER ANN , GORALCZYK REGINA , KILPERT CLAUS , MOHAJERI HASAN , RAEDERSTORFF DANIEL , DE SAIZIEU ANTOINE , SCHUELER GOEDE , WANG-SCHMIDT YING , WEHRLI CHRISTOF
IPC分类号： A61K31/365 , A23K1/16 , A23L1/30
摘要： Carnosol y/o rosmanol para usar como antidepresivo o reductor del comportamiento obsesivo-compulsivo.

22. 发明专利

PL2083809T3 Kompozycja dietetyczna lub farmaceutyczna zawierająca tricykliczne diterpeny do leczenia depresji 未知
公开(公告)号：PL2083809T3
公开(公告)日：2014-09-30
申请号：PL07856229
申请日：2007-11-22
申请人： DSM IP ASSETS BV
发明人： DE SAIZIEU ANTOINE , FOWLER ANN , GORALCZYK REGINA , KILPERT CLAUS , SCHUELER GOEDE , WEHRLI CHRISTOF
IPC分类号： A61K31/365 , A23K1/16 , A23K1/18 , A23L1/30 , A61K31/085 , A61K31/122 , A61K31/19 , A61K31/192 , A61K36/53 , A61K36/537 , A61P25/22 , A61P25/24 , A61P25/26

23. 发明专利

ES2399667T3 Nuevos agentes para el tratamiento de trastornos conectados con neurotransmisión deteriorada 未知
公开(公告)号：ES2399667T3
公开(公告)日：2013-04-02
申请号：ES07801575
申请日：2007-08-09
申请人： DSM IP ASSETS BV
发明人： FOWLER ANN , GORALCZYK REGINA , KILPERT CLAUS , SCHUELER GOEDE
IPC分类号： A61K36/53 , A61P25/24
摘要： Uso de una composición dietética o farmacéutica administrable por vía oral que comprende un extractoobtenido a partir de plantas del género Origanum por extracción con un disolvente o fluidos supercríticos,hidrodestilación para obtener aceites esenciales, o extracción/destilación con gases calientes en un proceso para:mantenimiento o la mejora de la atención y la concentración, la memoria y la capacidad para recordar, capacidad deaprendizaje, procesamiento del lenguaje, resolución de problemas y funcionamiento intelectual, mejora de la memoria a corto plazo, aumento del estado de alerta mental, aumento de la capacidad de concentración y la agudeza mental, intensificación de la vigilancia mental, reducción de la fatiga mental, refuerzo de la salud mental, mantenimiento de una función cognitiva equilibrada, regulación del hambre y la saciedad y la regulación de la actividad motora, uso como antidepresivo, mejorador del humor/vitalidad, aliviador del estrés, reductor de la ansiedad, reductor dela tensión, reductor de la tristeza, reductor de la infelicidad/descontento, reductor de la irritabilidad, reductor de ladisforia, reductor del comportamiento obsesivo-compulsivo, y/o relajante, o utilización como preventivo o normalizador de las alteraciones de los ritmos circadianos, con la salvedad de que la composición no incluye la combinación de orégano y extractos de Crataegus.

24. 发明专利

AT529107T 未知
公开(公告)号：AT529107T
公开(公告)日：2011-11-15
申请号：AT06753874
申请日：2006-05-24
申请人： DSM IP ASSETS BV
发明人： FOWLER ANN , RAEDERSTORFF DANIEL , SCHUELER GOEDE , SCHWAGER JOSEPH
IPC分类号： A61K31/343 , A61P11/00 , A61P19/02 , A61P19/06 , A61P29/00
摘要： The present invention relates to the use of compounds of the formula (I) wherein the clotted line is an optional bond; R1 is butyl or butyryl if R2 is hydroxyl but is butyl if R2 is hydrogen; or R1 and R2 taken together are 1-butylidene optionally substituted by hydroxyl, methyl, or 3-(α,&bgr;-dimethylacrylyloxy)-pentylidenyl; X is a residue selected from the group consisting of X1, X2, X3, X4, and X5; wherein X is X2, X3 or X5 if the dotted line in formula (I) is absent; and X is X1, X4 or X5 if the dotted line signifies a bond in formula (I) above; R3 is hydroxyl or butyryl; and n is 1 or 2, as agents for the prevention, control and treatment of conditions requiring modulation of inflammation in mammals. In another aspect, the present invention relates to the use of compounds of the formula (I) as active ingredients in the manufacture of medicaments/compositions for the prevention, control and treatment of conditions requiring modulation of inflammation. The compounds of formula (I) as defined above may also be useful (for the manufacture of a composition) for the management of pain, fever and injuries, especially sport injuries. Moreover, the compounds of formula (I) as defined above may also be useful (for the manufacture of a composition) for the maintenance and regeneration of articular cartilage.

25. 发明专利

ES2375302T3 DERIVADOS DE LIGUSTILIDA PARA EL TRATAMIENTO DE TRASTORNOS INFLAMATORIOS. 未知
公开(公告)号：ES2375302T3
公开(公告)日：2012-02-28
申请号：ES06753874
申请日：2006-05-24
申请人： DSM IP ASSETS BV
发明人： FOWLER ANN , RAEDERSTORFF DANIEL , SCHUELER GOEDE , SCHWAGER JOSEPH
IPC分类号： A61P11/00 , A61K31/343 , A61P19/02 , A61P19/06 , A61P29/00
摘要： Ligustilida para uso en la prevención, control y tratamiento de enfermedades degenerativas de las articulaciones en un mamífero.

26. 发明专利

DE602007011302D1 LIGUSTILID ZUR BEHANDLUNG VON ERKRANKUNGEN DES ZENTRALEN NERVENSYSTEMS 未知
公开(公告)号：DE602007011302D1
公开(公告)日：2011-01-27
申请号：DE602007011302
申请日：2007-08-10
申请人： DSM IP ASSETS BV
发明人： DE SAIZIEU ANTOINE , GORALCZYK REGINA , SCHUELER GOEDE
IPC分类号： A61K31/343 , A61P25/22 , A61P25/24

27. 发明专利

AT491446T 未知
公开(公告)号：AT491446T
公开(公告)日：2011-01-15
申请号：AT07786654
申请日：2007-08-10
申请人： DSM IP ASSETS BV
发明人： DE SAIZIEU ANTOINE , GORALCZYK REGINA , SCHUELER GOEDE
IPC分类号： A61K31/343 , A61P25/22 , A61P25/24
摘要： The present invention refers to compounds of the general formula (I) wherein R1 is hydrogen or hydroxy; R2 is butyl or butyryl if R1 is hydroxy, but R2 is butyl if R1 is hydrogen; or R3 and R2 taken together are 1-propylidene or 1-butylidene optionally substituted by hydroxy, methyl, or 3-(α, &bgr;-dimethylacryloyloxy); the dotted line is an optional bond; X is an optionally substituted aliphatic C4-residue selected from the group consisting of X1, X2, X3, X4, and X5; wherein X is X2, X3 or X5 if the dotted line in formula (I) is absent; and X is X1, X4 or X5 if the dotted line signifies a bond in formula (I) above; R3 and R4 are, independently from each other, hydrogen or hydroxy; and R5 is hydroxy or butyryl, for use in the treatment of disorders connected to impaired neurotransmission, as well as to dietary and pharmaceutical compositions containing such compounds, and their uses.

28. 发明专利

MX2009008079A DERIVADOS DE FENOL PARA USO COMO ADITIVOS PARA ALIMENTACION ANIMAL. 未知
公开(公告)号：MX2009008079A
公开(公告)日：2009-08-12
申请号：MX2009008079
申请日：2008-01-31
申请人： DSM IP ASSETS BV
发明人： SIMOES-NUNES CARLOS , SEON AURELIA , ORAZIO DANIEL D , SAIZIEU ANTOINE , SCHUELER GOEDE
IPC分类号： A23K1/00 , A61P31/04 , A61P1/14
摘要： La presente invención se relaciona con el uso de un grupo seleccionado de derivados del fenol como componentes de alimento para animales o aditivos para alimentos para mejorar el rendimiento de los animales así como al correspondiente alimento para animales o a los aditivos para alimento que los contienen.

29. 发明专利

DE602005012132D1 未知
公开(公告)号：DE602005012132D1
公开(公告)日：2009-02-12
申请号：DE602005012132
申请日：2005-10-21
申请人： DSM IP ASSETS BV
发明人： DE SAIZIEU ANTOINE , FOWLER ANN , GORALCZYK REGINA , MUSSLER BERND , SCHUELER GOEDE
IPC分类号： A61K31/37
摘要： The present invention refers to coumarin ethers of the formula (I), wherein R1 is H, OH or (E)-3-methyl-but-2-enyl, R2 is selected from the group consisting of methyl, 3-(4,5-dihydro-5,5-dimethyl-4-furanon-2-yl)-2-(E/Z)-butenyl, (E/Z)-3,7-dimethylocta-2,6-dienyl, 7-hydroxy-3,7-dimethyl-2-octen-6-on-yl and (E/Z,E/Z)-11-acetyl-oxy-3,7,11,11-tetramethyl-undeca-2,7-dien-10-on-yl, R3 is H, R1 and R2O together for the group —O—C(C(═CH2)CH3)H—CH2—O— or the group —C(H)═C(H)—C(CH3)2—O— or R2O and R3 together form the group —O—C(H)(C(CH3)2(H)—O—C(O)CH3)—CH2—, preferably to obliquin, for use as medicaments, especially for the treatment and/or prevention of disorders connected to impaired neurotransmission, as well as to dietary and pharmaceutical compositions and plant extracts containing such coumarin ethers and their uses.

30. 发明专利

AT418980T 未知
公开(公告)号：AT418980T
公开(公告)日：2009-01-15
申请号：AT05794149
申请日：2005-10-21
申请人： DSM IP ASSETS BV
发明人： DE SAIZIEU ANTOINE , FOWLER ANN , GORALCZYK REGINA , MUSSLER BERND , SCHUELER GOEDE
IPC分类号： A61K31/37
摘要： The present invention refers to coumarin ethers of the formula (I), wherein R1 is H, OH or (E)-3-methyl-but-2-enyl, R2 is selected from the group consisting of methyl, 3-(4,5-dihydro-5,5-dimethyl-4-furanon-2-yl)-2-(E/Z)-butenyl, (E/Z)-3,7-dimethylocta-2,6-dienyl, 7-hydroxy-3,7-dimethyl-2-octen-6-on-yl and (E/Z,E/Z)-11-acetyl-oxy-3,7,11,11-tetramethyl-undeca-2,7-dien-10-on-yl, R3 is H, R1 and R2O together for the group —O—C(C(═CH2)CH3)H—CH2—O— or the group —C(H)═C(H)—C(CH3)2—O— or R2O and R3 together form the group —O—C(H)(C(CH3)2(H)—O—C(O)CH3)—CH2—, preferably to obliquin, for use as medicaments, especially for the treatment and/or prevention of disorders connected to impaired neurotransmission, as well as to dietary and pharmaceutical compositions and plant extracts containing such coumarin ethers and their uses.

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