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21. 发明授权

US08588914B2 Implantable medical device with electrodes on multiple housing surfaces 有权
标题翻译：可植入医疗设备，电极在多个外壳表面
公开(公告)号：US08588914B2
公开(公告)日：2013-11-19
申请号：US11450127
申请日：2006-06-09
申请人： Ethan A. Rooney , Carl D. Wahlstrand , Gary W. King , Thomas E. Cross, Jr. , Richard T. Stone
发明人： Ethan A. Rooney , Carl D. Wahlstrand , Gary W. King , Thomas E. Cross, Jr. , Richard T. Stone
IPC分类号： A61N1/375
CPC分类号： A61N1/375 , A61N1/0504 , A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/36071 , A61N1/3756
摘要： An implantable medical device (IMD) with a housing and electrodes on at least two surfaces of the housing is described. The surfaces may be, for example, opposed, substantially parallel surfaces, e.g., top and bottom surfaces. Location of electrodes on multiple surfaces of the housing may allow the IMD to deliver stimulation to a variety of tissues and with a variety of current field configurations. For example, the IMD may deliver peripheral nerve field stimulation (PNFS) to one or more tissue areas via electrodes selected from one or both of the surfaces to, for example, reduce the sensation of pain in a tissue area proximate to an implantation site of the IMD without targeting a specific nerve. The IMD may be implanted between or within intra-dermal, deep dermal, or subcutaneous layers of the tissue of the patient to deliver PNFS to any one or more of these layers.
摘要翻译：描述了在壳体的至少两个表面上具有壳体和电极的可植入医疗装置（IMD）。表面可以是例如相对的基本上平行的表面，例如顶部和底部表面。电极在壳体的多个表面上的位置可以允许IMD将刺激递送到各种组织以及各种当前的现场配置。例如，IMD可以通过选自一个或两个表面的电极将外周神经区域刺激（PNFS）递送到一个或多个组织区域，以例如减少接近植入部位的组织区域中的疼痛感觉 IMD没有针对特定的神经。 IMD可以植入在患者组织的真皮内，深层皮肤或皮下层之间或内，以将PNFS递送到这些层中的任何一个或多个层。

22. 发明授权

US09084901B2 Cranial implant 有权
标题翻译：颅内植入
公开(公告)号：US09084901B2
公开(公告)日：2015-07-21
申请号：US11413618
申请日：2006-04-28
申请人： Carl D. Wahlstrand
发明人： Carl D. Wahlstrand
IPC分类号： A61N1/375 , A61N1/05 , A61B5/0478 , A61B5/00 , A61N1/36
CPC分类号： A61B5/0478 , A61B5/6868 , A61N1/0529 , A61N1/0534 , A61N1/0539 , A61N1/3605 , A61N1/3606 , A61N1/36082 , A61N1/36135 , A61N1/375
摘要： Implantable medical devices (IMD) configured for implantation within a recess formed in a cranium of a patient, as well as associated methods, are described. In some embodiments, the IMD includes a top external surface and another adjacent external surface, e.g., a side surface, which are oriented with respect to each other to define an acute angle. A connection module for an electrical lead or catheter may be included on the top external surface. Embodiments of the invention may facilitate implantation of an IMD within a recess formed in the cranium of a patient at a location remote to an incision made in the scalp of the patient.
摘要翻译：描述了被配置用于植入在形成在患者的颅骨中的凹部内的植入式医疗装置（IMD）以及相关联的方法。在一些实施例中，IMD包括顶部外表面和相对于彼此定向以限定锐角的另一相邻外表面，例如侧表面。用于电引线或导管的连接模块可以包括在顶部外表面上。本发明的实施例可以有助于将IMD植入位于患者头颅内的凹陷部位于远离患者头皮的切口的位置。

23. 发明授权

US08934973B2 Hub for implantable medical leads 有权
标题翻译：用于可植入医疗线的集线器
公开(公告)号：US08934973B2
公开(公告)日：2015-01-13
申请号：US13376141
申请日：2010-06-21
申请人： Carl D. Wahlstrand , Dale F. Seeley , Gabriela C. Molnar , Lisa M. Johanek
发明人： Carl D. Wahlstrand , Dale F. Seeley , Gabriela C. Molnar , Lisa M. Johanek
IPC分类号： A61N1/05 , H04L12/18 , H04L12/58 , H04W72/00 , H04W72/12
CPC分类号： H04L12/189 , A61N1/3752 , H01R13/5224 , H01R24/58 , H01R31/02 , H01R2107/00 , H01R2201/12 , H04L51/38 , H04W72/005 , H04W72/1273 , H04W72/1289
摘要： A hub (200) includes a first lead receptacle having a plurality of contacts (280) for electrically coupling a lead to an implantable electrical device. The hub further contains a second lead receptacle having a plurality of contacts for electrically coupling a lead to the implantable electrical device. At least one of the plurality of contacts of the first receptacle is a contact of the second receptacle. Such a configuration may allow for the overall size of the hub to be reduced relative to a hub where each discrete contact of the hub corresponds to a discrete contact or electrical channel of the implantable electrical device.
摘要翻译：轮毂（200）包括具有用于将引线电耦合到可植入电气装置的多个触点（280）的第一引线插座。轮毂还包括具有用于将引线电耦合到可植入电气装置的多个触点的第二引线插座。第一容器的多个触点中的至少一个是第二插座的触点。这种构造可以允许毂的总体尺寸相对于轮毂减小，其中毂的每个离散接触对应于可植入电气设备的离散接触或电通道。

24. 发明授权

US08929993B2 Electrode arrangements for suborbital foramen medical lead 有权
标题翻译：用于亚轨道孔的医疗铅的电极安排
公开(公告)号：US08929993B2
公开(公告)日：2015-01-06
申请号：US13376152
申请日：2010-06-21
申请人： Carl D. Wahlstrand , Dale F. Seeley , Lisa M. Johanek , John E. Kast , Phillip C. Falkner , Louis P. Vera-Portocarrero
发明人： Carl D. Wahlstrand , Dale F. Seeley , Lisa M. Johanek , John E. Kast , Phillip C. Falkner , Louis P. Vera-Portocarrero
IPC分类号： A61N1/05
CPC分类号： A61N1/0551
摘要： A medical lead includes a plurality of electrodes on an annular distal end portion of the lead. The electrodes may be arranged along a circle concentric with the center of a void defined by the annular portion. The annular medical lead design is well suited for application of electrical signal therapy to the suborbital nerve at its point of exit from the inferior orbital foramen in the skull.
摘要翻译：医疗引线包括在引线的环形远端部分上的多个电极。电极可以沿与由环形部分限定的空隙的中心同心的圆排布置。环形医疗引线设计非常适合于在颅骨下游轨道孔出口点处向眶下神经施加电信号治疗。

25. 发明授权

US08538549B2 Programming interface for stimulation therapy 有权
标题翻译：刺激治疗的编程界面
公开(公告)号：US08538549B2
公开(公告)日：2013-09-17
申请号：US13592918
申请日：2012-08-23
申请人： Steven M. Goetz , Richard T. Stone , Warren W. Ball , Carl D. Wahlstrand
发明人： Steven M. Goetz , Richard T. Stone , Warren W. Ball , Carl D. Wahlstrand
IPC分类号： A61N1/08
CPC分类号： A61N1/0534 , A61N1/36071 , A61N1/36157 , A61N1/36185 , A61N1/37247
摘要： The disclosure is directed to programming implantable stimulators to deliver stimulation energy via one or more implantable leads having complex electrode array geometries. The disclosure also contemplates guided programming to select electrode combinations and parameter values to support efficacy. The techniques may be applied to a programming interface associated with a clinician programmer, a patient programmer, or both. A user interface permits a user to view electrodes from different perspectives relative to the lead. For example, the user interface provides a side view of a lead and a cross-sectional view of the lead. The user interface may include an axial control medium to select and/or view electrodes at different axial positions along the length of a lead, and a rotational control medium to select and/or view electrodes at different angular positions around a circumference of the lead.
摘要翻译：本公开涉及编程可植入刺激器以通过具有复杂电极阵列几何形状的一个或多个可植入引线输送刺激能量。本公开还考虑了引导编程以选择电极组合和参数值以支持功效。这些技术可以应用于与临床医生程序员，患者程序员或两者相关联的编程接口。用户界面允许用户从相对于铅的不同角度来观察电极。例如，用户界面提供引线的侧视图和引线的横截面图。用户界面可以包括轴向控制介质，用于选择和/或查看沿引线长度的不同轴向位置处的电极;以及旋转控制介质，用于选择和/或查看围绕引线圆周的不同角位置处的电极。

26. 发明授权

US08509920B2 Electrode arrangements for medical lead 有权
标题翻译：医用铅电极装置
公开(公告)号：US08509920B2
公开(公告)日：2013-08-13
申请号：US13376133
申请日：2010-06-21
申请人： Carl D. Wahlstrand , Dale F. Seeley , Gabriela C. Molnar
发明人： Carl D. Wahlstrand , Dale F. Seeley , Gabriela C. Molnar
IPC分类号： A61N1/04
CPC分类号： A61N1/0551 , A61N1/0556
摘要： An implantable medical lead includes a lead body having a proximal portion having a longitudinal axis and an arcuate distal body portion extending in the direction of the longitudinal axis. The arcuate distal body portion has a concave surface. The lead includes a plurality of elongate electrodes disposed at the arcuate distal end portion of the lead body along the concave surface. The electrodes extend substantially parallel to the longitudinal axis of the lead body.
摘要翻译：可植入医疗引线包括具有纵向轴线的近端部分和沿着纵向轴线方向延伸的弓形远侧主体部分的引线主体。弓形的远侧主体部分具有凹面。引线包括沿着凹面设置在引线主体的弓形远端部分处的多个细长电极。电极基本上平行于引线主体的纵向轴线延伸。

27. 发明授权

US08121694B2 Therapy control based on a patient movement state 有权
标题翻译：基于患者运动状态的治疗控制
公开(公告)号：US08121694B2
公开(公告)日：2012-02-21
申请号：US12237799
申请日：2008-09-25
申请人： Gregory F. Molnar , Steven S. Gill , Keith A. Miesel , Mark S. Lent , Timothy J. Denison , Eric J. Panken , Carl D. Wahlstrand , Jonathan C. Werder
发明人： Gregory F. Molnar , Steven S. Gill , Keith A. Miesel , Mark S. Lent , Timothy J. Denison , Eric J. Panken , Carl D. Wahlstrand , Jonathan C. Werder
IPC分类号： A61N1/18
CPC分类号： A61B5/04014 , A61B5/0006 , A61B5/4082 , A61B5/6814 , A61N1/36003 , A61N1/36014 , A61N1/36025 , A61N1/36067 , A61N1/36082
摘要： A movement state of a patient is detected based on brain signals, such as an electroencephalogram (EEG) signal. In some examples, a brain signal within a dorsal-lateral prefrontal cortex of a brain of the patient indicative of prospective movement of the patient may be sensed in order to detect the movement state. The movement state may include the brain state that indicates the patient is intending on initiating movement, initiating movement, attempting to initiate movement or is actually moving. In some examples, upon detecting the movement state, a movement disorder therapy is delivered to the patient. In some examples, the therapy delivery is deactivated upon detecting the patient is no longer in a movement state or that the patient has successfully initiated movement. In addition, in some examples, the movement state detected based on the brain signals may be confirmed based on a signal from a motion sensor.
摘要翻译：基于诸如脑电图（EEG）信号的脑信号检测患者的运动状态。在一些示例中，可以检测指示患者的预期运动的患者的脑的背侧前额叶皮层内的脑信号，以便检测运动状态。运动状态可以包括指示患者打算启动运动，启动运动，尝试启动运动或实际运动的脑状态。在一些示例中，在检测到运动状态时，将运动障碍治疗递送给患者。在一些示例中，在检测到患者不再处于运动状态或患者已成功启动运动时，治疗递送被停用。此外，在一些示例中，可以基于来自运动传感器的信号来确认基于脑信号检测到的运动状态。

28. 发明授权

US07890165B2 Implantable medical device with reduced MRI image distortion 有权
标题翻译：植入式医疗器械减少MRI图像失真
公开(公告)号：US07890165B2
公开(公告)日：2011-02-15
申请号：US12706266
申请日：2010-02-16
申请人： Carl D. Wahlstrand , Mark J. Conroy , John E. Kast , Erik R. Scott
发明人： Carl D. Wahlstrand , Mark J. Conroy , John E. Kast , Erik R. Scott
IPC分类号： A61N1/16
CPC分类号： G01R33/56572 , A61B5/055 , A61B34/10 , A61N1/05 , A61N1/0529 , A61N1/0551 , A61N1/08 , A61N1/086 , A61N1/3605 , A61N1/36125 , A61N1/3718 , A61N1/375 , A61N1/3758 , A61N1/378 , G01R33/3875 , H01M2/0217 , H01M2/026 , H01M2/0275 , H01M2/0285 , H01M2/0404 , H01M2/1066 , H01M2/22 , H01M2/263 , H01M2/30 , H01M10/0431 , H01M10/052 , H01M10/0525 , H01M10/0587 , H01M2220/30 , Y10T29/49 , Y10T29/49002
摘要： An implantable medical device includes a housing and a circuit board provided within the housing. The circuit board includes a plurality of electronic components electrically coupled thereto. At least one non-functional component is provided on the circuit board and formed from a material that has an electromagnetic permeability configured to reduce the amount of image distortion caused by at least one of the plurality of electronic components when the device is subject to a magnetic field during an MRI scan.
摘要翻译：可植入医疗装置包括壳体和设置在壳体内的电路板。电路板包括与其电耦合的多个电子部件。至少一个非功能部件设置在电路板上，并且由具有电磁渗透性的材料形成，该材料被配置为当该器件经受磁性时减少由至少一个电子元件引起的图像失真量在MRI扫描期间。

29. 发明授权

US07848817B2 Coupling module of a modular implantable medical device 有权
标题翻译：模块化可植入医疗器械的耦合模块
公开(公告)号：US07848817B2
公开(公告)日：2010-12-07
申请号：US10731699
申请日：2003-12-09
申请人： Darren A. Janzig , Carl D. Wahlstrand , Robert M. Skime , Mark S. Lent , Keith A. Miesel , James E. Cabak
发明人： Darren A. Janzig , Carl D. Wahlstrand , Robert M. Skime , Mark S. Lent , Keith A. Miesel , James E. Cabak
IPC分类号： A61N1/00
CPC分类号： A61N1/375 , A61N1/3605 , A61N1/3754 , A61N1/3758
摘要： In an implantable medical device having individual modules, a coupling module couples the modules to one another. The coupling module supports electrical and/or mechanical coupling of the modules. The coupling module may assume a variety of shapes or configurations. The various embodiments of the coupling module may offer the modules varying degrees of freedom of movement relative to one another.
摘要翻译：在具有各个模块的可植入医疗装置中，耦合模块将模块彼此连接。联接模块支持模块的电气和/或机械耦合。联接模块可呈现各种形状或构型。联接模块的各种实施例可以提供模块相对于彼此的不同移动自由度。

30. 发明申请

US20090299165A1 IMPLANTATION OF IMPLANTABLE MEDICAL DEVICE 审中-公开
公开(公告)号：US20090299165A1
公开(公告)日：2009-12-03
申请号：US12538623
申请日：2009-08-10
申请人： Ruchika Singhal , Carl D. Wahlstrand , Robert M. Skime , Steven J. Urquhart
发明人： Ruchika Singhal , Carl D. Wahlstrand , Robert M. Skime , Steven J. Urquhart
IPC分类号： A61B5/00 , A61B6/00
CPC分类号： A61B5/6864 , A61B5/107 , A61B5/686 , A61B5/6868
摘要： In general, the invention is directed to strategies pertaining to implantation of an implantable medical device between a scalp and a skull of the patient. The invention pertains to collection of data such as data pertaining to the skull of the patient, the scalp of the patient, the vascular structure or neurological structures in the head of the patient, and the like. The data may be in the form of images, such as images generated by X-ray, magnetic resonance imaging, CT-scan and fluoroscopy. A surgeon can use the collected data to determine, for example, whether the patient is a candidate for a cranial implantation, whether the patient's skull and scalp can support the implantation, what configuration of device should be implanted, where the device should be implanted, and how the surgical incisions should be made.

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