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21. 发明专利

PT930933E 未知
公开(公告)号：PT930933E
公开(公告)日：2003-07-31
申请号：PT98941547
申请日：1998-08-05
申请人： CENTRE NAT RECH SCIENT
发明人： BIBETTE JEROME , FICHEUX MARIE-FRANCOISE , CALDERON FERNANDO LEAL , BONNAKDAR LIDA
IPC分类号： A61K9/113 , B01D17/04 , B01D17/05 , B01F3/08 , B01F7/00 , B01J13/00 , B01F17/00
摘要： A method for the controlled release of an active principle contained in a multiple water-in-oil-in-water emulsion characterized in that the multiple emulsion comprises an invert emulsion Ei with an aqueous phase A1 containing at least a hydrophilic active principle. The emulsion Ei is dispersed in the form of direct emulsion droplets Ed, in a continuous aqueous phase A2, with the two emulsions Ed and Ei stabilized by at least a surfactant, present in their respective continuous phases. The multiple emulsion is brought in the presence of an effective amount of an agent for transforming it into a direct emulsion and induce the release of the active principle, contained in the aqueous phase A1 of emulsion Ei, in the aqueous phase A2.

22. 发明专利

AU1288201A Composite nanospheres and their conjugates with biomolecules 未知
公开(公告)号：AU1288201A
公开(公告)日：2001-05-14
申请号：AU1288201
申请日：2000-11-06
申请人： BIO MERIEUX , CENTRE NAT RECH SCIENT , MONDAIN MONVAL OLIVIER
发明人： ELAISSARI ABDELHAMID , BOSC ERIC , PICHOT CHRISTIAN , MANDRAND BERNARD , BIBETTE JEROME
IPC分类号： G01N33/545 , A61K9/51 , A61K31/7088 , A61K45/00 , A61K47/02 , A61K47/04 , A61K47/32 , A61K47/48 , A61K48/00 , A61P43/00 , C09D11/00 , G01N33/543 , G01N33/546

23. 发明专利

CA2299164A1 PROCEDE POUR PREPARER DES EMULSIONS CONCENTREES ET CALIBREES EN UNE PHASE DE VISCOSITE ELEVEE DONT DES EMULSIONS DE BITUMES 未知
公开(公告)号：CA2299164A1
公开(公告)日：1999-02-11
申请号：CA2299164
申请日：1998-07-28
申请人： CENTRE NAT RECH SCIENT
发明人： LEAL CALDERON FERNANDO , BIBETTE JEROME , GUIMBERTEAU FLORENCE
IPC分类号： B01F23/47 , C09K23/18 , B01F3/10
摘要： La présente invention a pour objet un procédé utile pour émulsionner une première phase hydrophobe ou hydrophile et de viscosité comprise entre 1 et 5000 Pa.s ou supérieure avec une seconde phase non miscible à ladite première phase et notamment des émulsions de bitumes concentrées. Elle se rapporte en outre aux émulsions ainsi obtenues.

24. 发明专利

FR3003772B1 PROCEDE ET SYSTEME DE SUIVI DE LA CINETIQUE DE REACTIONS 未知
公开(公告)号：FR3003772B1
公开(公告)日：2015-05-01
申请号：FR1352944
申请日：2013-03-29
申请人： CENTRE NAT RECH SCIENT
发明人： BOITARD LAURENT , BIBETTE JEROME , BAUDRY JEAN
IPC分类号： B01J19/00 , G01N35/08

25. 发明专利

ES2220560T3 NANOESFERAS A BASE DE MATERIALES COMPUESTOS Y SUS CONJUGADOS CON BIOMOLECULAS. 未知
公开(公告)号：ES2220560T3
公开(公告)日：2004-12-16
申请号：ES00974662
申请日：2000-11-06
申请人： BIO MERIEUX , CENTRE NAT RECH SCIENT
发明人： ELAISSARI ABDELHAMID , BOSC ERIC , PICHOT CHRISTIAN , MANDRAND BERNARD , BIBETTE JEROME , MONDAIN-MONVAL OLIVIER
IPC分类号： G01N33/545 , A61K9/51 , A61K31/7088 , A61K45/00 , A61K47/02 , A61K47/04 , A61K47/32 , A61K47/48 , A61K48/00 , A61P43/00 , C09D11/00 , G01N33/543 , G01N33/546
摘要： Nanoesferas de materiales compuestos (composites), caracterizadas por el hecho de que, éstas, presentan un diámetro comprendido dentro de unos márgenes situados entre aproximadamente 50 y 1000 nm, más ó menos un 5%, y que éstas comprenden: - un núcleo esencialmente líquido, constituido por una fase orgánica y por nanopartículas orgánicas distribuidas de forma homogénea, en el interior de la fase orgánica, y - una envoltura constituida por lo menos por un polímero hidrófilo, el cual procede de la polimerización de por lo menos un monómero hidrosoluble, de una forma particular, una N-alquiacrilamida, o una N, N-dialquil- acrilamida.

26. 发明专利

DE60107073D1 未知
公开(公告)号：DE60107073D1
公开(公告)日：2004-12-16
申请号：DE60107073
申请日：2001-05-09
申请人： CENTRE NAT RECH SCIENT
发明人： LEAL CALDERON FERNANDO , GORRIA PHILIPPE , BIBETTE JEROME
IPC分类号： B01F3/08 , B01F9/10
摘要： A method for preparing a monodispersed double water/oil/water emulsion, comprises: a) subjecting a polydispered oil-in-water emulsion Ei comprising 55 to 99 wt. % of an aqueous phase, to a controlled shearing to obtain the corresponding monodispersed invert emulsion; b) adding to the emulsion, without phase inversion, the necessary amount of diluting oil phase so that the aqueous phase of the resulting emulsion represents at least 50 wt. % of the emulsion total weight; and c) introducing the resulting emulsion into a high pressure homogenizer, together with a continuous aqueous phase, the respective amounts of the emulsion and the continuous aqueous phase being such that the resulting double emulsion comprises up to 50 wt. % of invert emulsion droplets relative to the emulsion total weight, the continuous aqueous phase comprising a hydrophilic surfactant concentration not more that 0.02 times the critical micellar concentration.

27. 发明专利

AT281881T 未知
公开(公告)号：AT281881T
公开(公告)日：2004-11-15
申请号：AT01931824
申请日：2001-05-09
申请人： CENTRE NAT RECH SCIENT
发明人： LEAL CALDERON FERNANDO , GORRIA PHILIPPE , BIBETTE JEROME
IPC分类号： B01F3/08 , B01F9/10
摘要： A method for preparing a monodispersed double water/oil/water emulsion, comprises: a) subjecting a polydispered oil-in-water emulsion Ei comprising 55 to 99 wt. % of an aqueous phase, to a controlled shearing to obtain the corresponding monodispersed invert emulsion; b) adding to the emulsion, without phase inversion, the necessary amount of diluting oil phase so that the aqueous phase of the resulting emulsion represents at least 50 wt. % of the emulsion total weight; and c) introducing the resulting emulsion into a high pressure homogenizer, together with a continuous aqueous phase, the respective amounts of the emulsion and the continuous aqueous phase being such that the resulting double emulsion comprises up to 50 wt. % of invert emulsion droplets relative to the emulsion total weight, the continuous aqueous phase comprising a hydrophilic surfactant concentration not more that 0.02 times the critical micellar concentration.

28. 发明专利

DE60010500D1 未知
公开(公告)号：DE60010500D1
公开(公告)日：2004-06-09
申请号：DE60010500
申请日：2000-11-06
申请人： BIO MERIEUX MARCY L ETOILE , CENTRE NAT RECH SCIENT
发明人： ELAISSARI ABDELHAMID , BOSC ERIC , PICHOT CHRISTIAN , MANDRAND BERNARD , BIBETTE JEROME , MONDAIN-MONVAL OLIVIER
IPC分类号： G01N33/545 , A61K9/51 , A61K31/7088 , A61K45/00 , A61K47/02 , A61K47/04 , A61K47/32 , A61K47/48 , A61K48/00 , A61P43/00 , C09D11/00 , G01N33/543 , G01N33/546

29. 发明专利

AT266201T 未知
公开(公告)号：AT266201T
公开(公告)日：2004-05-15
申请号：AT00974662
申请日：2000-11-06
申请人： BIO MERIEUX , CENTRE NAT RECH SCIENT
发明人： ELAISSARI ABDELHAMID , BOSC ERIC , PICHOT CHRISTIAN , MANDRAND BERNARD , BIBETTE JEROME , MONDAIN-MONVAL OLIVIER
IPC分类号： G01N33/545 , A61K9/51 , A61K31/7088 , A61K45/00 , A61K47/02 , A61K47/04 , A61K47/32 , A61K47/48 , A61K48/00 , A61P43/00 , C09D11/00 , G01N33/543 , G01N33/546

30. 发明专利

DE69723460T2 未知
公开(公告)号：DE69723460T2
公开(公告)日：2004-04-15
申请号：DE69723460
申请日：1997-11-28
申请人： CENTRE NAT RECH SCIENT
发明人： MAYER PASCAL , BIBETTE JEROME , VIOVY JEAN-LOUIS
IPC分类号： B01D57/02 , B03C1/32 , B03C5/00 , C12N15/09 , G01N27/447
摘要： The invention concerns a method for separating particles or molecules whereby these particles or molecules are introduced in a separating medium and a moving force is applied to them in said medium. The method is characterised in that the separating medium is a ferrofluid, i.e. a colloidal suspension of magnetic particles and a magnetic field is applied to this ferrofluid generating therein at least an alternation of a zone rich in magnetic particles and a zone poor in magnetic particles, part at least of the region of the ferrofluid in which this alternation is generated is passed through by the particles or molecules to be separated during their migration.

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