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21. 发明授权

US5280035A Cycloalkylene azoles and their use as aromatase inhibitors 失效
标题翻译：环亚烷基唑类及其作为芳香酶抑制剂的用途
公开(公告)号：US5280035A
公开(公告)日：1994-01-18
申请号：US889331
申请日：1992-05-28
申请人： Rolf Bohlmann , Peter Strehlke , David Henderson , Martin Schneider , Yukishige Nishino
发明人： Rolf Bohlmann , Peter Strehlke , David Henderson , Martin Schneider , Yukishige Nishino
IPC分类号： A61K31/415 , A61K31/41 , A61K31/4174 , A61K31/4178 , A61K31/4192 , A61K31/4196 , A61P5/32 , A61P13/00 , A61P13/02 , A61P15/00 , A61P35/00 , C07D233/56 , C07D233/58 , C07D233/64 , C07D249/04 , C07D249/08 , C07D401/08 , C07D405/08 , C07D409/06 , C07D409/08 , C07D521/00 , C07D407/06
CPC分类号： C07D231/12 , C07D233/56 , C07D249/04 , C07D249/08
摘要： The disclosure relates to cycloalkylene azoles of general Formula I ##STR1## wherein ##STR2## is a carbocyclic or carbopolycyclic group optionally carrying at least one alkyl substituent,is the grouping ##STR3## an oxygen or sulfur atom, and Y and Z, independently of each other, are ##STR4## or a nitrogen atom, as well as their pharmaceutically compatible addition salts with acids as well as processes for production thereof. The compounds possess strongly aromatase-inhibiting activity and are suitable for the preparation of medicinal agents.Methods for treating estrogen induced or stimulated tumors, male infertility, and impending cardiac infarction with these compounds are also provided as well as methods for inhbiiting female fertility.
摘要翻译：本公开涉及通式I的环亚烷基唑类（I）其中，IMAGE是任选携带至少一个烷基取代基的碳环或多碳环，是氧或硫原子，Y和Z 彼此独立地是氮或氮原子，以及它们与酸的药学上相容的加成盐以及其制备方法。该化合物具有强烈的芳香酶抑制活性，适用于制备药剂。还提供了用于治疗雌激素诱导或刺激的肿瘤，男性不育症和即将发生的这些化合物的心肌梗死的方法以及用于吸收女性生殖力的方法。

22. 发明授权

US4814327A 11 .beta.-(4-isopropenylphenyl)estra-4,9-dienes, their production, and pharmaceutical preparations containing same 失效
标题翻译： 11β-（4-异丙烯基苯基）雌-4,9-二烯，它们的生产和含有它们的药物制剂
公开(公告)号：US4814327A
公开(公告)日：1989-03-21
申请号：US077359
申请日：1987-07-24
申请人： Eckhard Ottow , Rudolf Wiechert , Gunter Neef , Sybille Beier , Walter Elger , David Henderson
发明人： Eckhard Ottow , Rudolf Wiechert , Gunter Neef , Sybille Beier , Walter Elger , David Henderson
IPC分类号： A61K31/565 , A61P5/00 , A61P13/02 , A61P15/00 , C07J20060101 , C07J1/00 , C07J17/00 , C07J21/00 , C07J41/00 , A61K31/56
CPC分类号： C07J1/0081 , C07J17/00 , C07J21/006 , C07J41/0094
摘要： 11 .beta.-(4-isopropenylphenyl)-estra-4,9-dienes of general Formula I ##STR1## wherein X is an oxygen atom or a hydroxyimino grouping N OH,R.sup.1 is a hydrogen atom or a methyl group,R.sup.2 is a hydrogen atom or an acyl residue of 1-10 carbon atoms,R.sup.3 is a hydrogen atom, the cyanomethyl group, --(CH.sub.2).sub.n --, CH.sub.2 Z, --CH.dbd.CH--(CH.sub.2).sub.m Z or --C.tbd.C--Y wherein n=0 to 5 and m=1 to 4, Z meaning a hydrogen atom or the OR.sup.4 group with R.sup.4 meaning a hydrogen atom, an alkyl or alkanoyl group each of 1-4 carbon atoms, and Y meaning a hydrogen, chlorine, fluorine, iodine or bromine atom, an alkyl, hydroxyalkyl, alkoxyalkyl or acyloxyalkyl group each of 1-4 carbon atoms in the alkyl or acyl residue, possess antiprogestational activity.
摘要翻译： 11β-（4-异丙烯基苯基） - 雌-4,9-二烯通式Ⅰ其中X是氧原子或羟基亚氨基，N OH，R 1是氢原子或甲基，R 2 是氢原子或1-10个碳原子的酰基，R3是氢原子，氰基甲基， - （CH2）n-，CH2Z，-CH = CH-（CH2）mZ或-C3OND CY其中n = 0〜5，m = 1〜4，Z表示氢原子或具有R4的OR4基团，表示氢原子，1-4个碳原子的烷基或烷酰基，Y表示氢，氯，氟，碘或溴原子，烷基或酰基残基中1-4个碳原子的烷基，羟基烷基，烷氧基烷基或酰氧基烷基具有抗供体活性。

23. 发明授权

US4609651A 11.beta.-arylestradienes, their production, and pharmaceutical preparations containing same 失效
标题翻译： 11β-芳基染料，它们的生产和含有它们的药物制剂
公开(公告)号：US4609651A
公开(公告)日：1986-09-02
申请号：US685088
申请日：1984-12-21
申请人： Ralph Rohde , Klaus Annen , Gunter Neef , Rudolf Wiechert , Sybille Beier , Walter Elger , David Henderson
发明人： Ralph Rohde , Klaus Annen , Gunter Neef , Rudolf Wiechert , Sybille Beier , Walter Elger , David Henderson
IPC分类号： A61K31/565 , A61P5/38 , C07F7/08 , C07F7/10 , C07J1/00 , C07J21/00 , C07J31/00 , C07J41/00 , C07J43/00 , C07J51/00 , C07J53/00 , C07J63/00 , C07J71/00 , A61K31/56
CPC分类号： C07J31/006 , C07F7/0818 , C07F7/0827 , C07F7/10 , C07J1/0081 , C07J21/006 , C07J41/0083 , C07J43/006 , C07J51/00 , C07J63/008 , C07J71/001
摘要： 11.beta.-Arylestradienes of general Formula I are disclosed ##STR1## wherein R.sup.2 is a hydrogen atom, a methyl group, or an ethyl group,R.sup.3 is a hydrogen atom or an acyl group,R.sup.1 and A-B have various meanings,which possess antigestagen and antimineralocorticoid activity.
摘要翻译： 11β-一般式I的丙烯雌二醇公开了其中R 2是氢原子，甲基或乙基，R 3是氢原子或酰基，R 1和AB具有各种含义，具有抗老化和抗皮质激素活性。

24. 发明授权

US4356770A Overflying munitions device and system 失效
标题翻译：过载弹药装置和系统
公开(公告)号：US4356770A
公开(公告)日：1982-11-02
申请号：US92898
申请日：1979-11-09
申请人： John V. Atanasoff , W. Kenneth Clark , David Henderson , Kenneth W. Wreghitt
发明人： John V. Atanasoff , W. Kenneth Clark , David Henderson , Kenneth W. Wreghitt
IPC分类号： B64D7/08 , F42B10/26 , F42B12/04 , F42B12/10 , F42B15/10 , F42B25/24
CPC分类号： B64D7/08 , F42B10/26 , F42B12/04 , F42B12/10 , F42B15/105
摘要： In a munitions system, a cylindrical canister is fired over a target. The canister carries a target sensing infrared device and, when a target is detected, a projectile is fired downward from the bottom of the overflying missile. A spinning motion is imparted to the missile to stabilize its flight, and a wobbling motion is imparted to the missile to provide a larger target area. The projectile forms a concave lower end to the missile and is fired by an explosive charge.
摘要翻译：在一个弹药系统中，一个圆柱形罐被射出一个目标。所述罐携带目标感测红外线装置，并且当检测到目标时，从所述飞越的底部向下射出射弹。向导弹传递旋转动作以稳定其飞行，并且向导弹施加摆动的动作以提供更大的目标区域。射弹形成导弹的凹下端，并被炸药引爆。

25. 发明授权

US4138757A Ultrasonic film cleaning apparatus 失效
标题翻译：超声波清洗设备
公开(公告)号：US4138757A
公开(公告)日：1979-02-13
申请号：US888195
申请日：1978-03-20
申请人： David Henderson , David B. Digel
发明人： David Henderson , David B. Digel
IPC分类号： B08B3/12 , B65H23/00 , G03B21/00 , G03D15/00 , B08B11/00
CPC分类号： B08B3/123 , G03D15/00
摘要： An ultrasonic liquid film cleaning device having means for moving a film strip at high speeds between a pair of oppositely moving cleaning strips. The cleaning strips and the film are positioned for movement between a pair of beds which act as guides and compression surfaces for the sandwiched assembly of cleaning strips and film. Cleaning fluid is piped to the bed to wet the cleaning strips and thereby assist in the cleaning action. An ultrasonic device is mounted in each bed to activate the fluid which is absorbed by the cleaning strips. This activation of the fluid increases the cleaning power of the strips as they pass against the film.
摘要翻译：一种超声波液膜清洁装置，具有用于在一对相对移动的清洁条之间高速移动胶片条的装置。清洁条和膜定位成在一对床之间移动，这对床用作导向件和用于夹持的清洁带和膜的组件的压缩表面。将清洁液管道输送到床上以润湿清洁带，从而有助于清洁动作。超声波装置安装在每个床中以激活被清洁带吸收的流体。流体的这种激活增加了条带穿过薄膜时的清洁力。

26. 发明授权

US3977145A Horizontal siding panel joint support 失效
标题翻译：水平面板接头支撑
公开(公告)号：US3977145A
公开(公告)日：1976-08-31
申请号：US562119
申请日：1975-03-26
申请人： Gerald B. Dobby , David Henderson
发明人： Gerald B. Dobby , David Henderson
IPC分类号： E04D3/362 , E04F13/08 , E04D3/366
CPC分类号： E04F13/0864 , E04D3/362
摘要： A joint support is adapted to be disposed beneath a joint at adjacent ends of horizontally disposed overlapping siding panels to support same and to assist in preventing the formation of a gap at said joint by virtue of inward buckling or deflection of one of the panels relative to the other. The joint support, as seen in a cross-section view taken at right angles to the longitudinal dimension of the panels in the installed condition has a wedge taper and has minimum thickness adjacent a first end which, in use, is uppermost. The opposite end of the joint support is contoured or shaped to overlie and accommodate the panel holding lip of a preceding lower panel. The first end of the joint support has an outwardly and downwardly turned portion adapted to fit over the panel holding lip or lips of the panels which the joint support, in use, underlies and the opposite end of the joint support includes shallow hook means thereon for snap fitting engagement over the holding lip of the preceding lower panel.

27. 外观设计

USD726349S1 Luminaire 有权
公开(公告)号：USD726349S1
公开(公告)日：2015-04-07
申请号：US29423346
申请日：2012-05-31
申请人： Fredric S. Maxik , David Henderson , Mark Penley Boomgaarden , Addy S. Widjaja , Emilio Flores , Shane Sullivan , Wei Sun
设计人： Fredric S. Maxik , David Henderson , Mark Penley Boomgaarden , Addy S. Widjaja , Emilio Flores , Shane Sullivan , Wei Sun

28. 发明授权

US08777512B2 Vertically stackable and retrofittable traffic cone linking 失效
标题翻译：垂直可堆叠和可改装的交通锥连接
公开(公告)号：US08777512B2
公开(公告)日：2014-07-15
申请号：US13436191
申请日：2012-03-30
申请人： David Henderson
发明人： David Henderson
IPC分类号： E01F9/00 , E01F9/012
CPC分类号： E01F13/02 , E01F9/654 , E01F9/688 , E01F13/028
摘要： A vertically stackable and retrofittable traffic cone linking system having a plurality of linking cuffs substantially conically shaped linking cuffs having four connection points, sized and configured to be removably secured to a standard traffic cone and a traffic cone linking connector removably connected to the linking cuffs. Once the traffic cone linking cuff is linked to the traffic cone linking connector, the traffic cone linking system can be can be arranged in a predetermined configuration or arrangement to alert onlookers of a particular hazard or to impede access to a given location.
摘要翻译：一种可垂直堆叠和可改装的交通锥形连接系统，其具有多个基本上圆锥形的连接箍，其连接箍具有四个连接点，所述连接箍具有四个连接点，其尺寸和构造可移除地固定到标准交通锥体，以及可移除地连接到所述连接箍的交通锥形连接连接器。一旦将交通锥形连接袖带连接到交通锥形连接连接器，则交通锥形连接系统可以被布置成预定的配置或布置，以提醒旁观者特定危险或妨碍访问给定位置。

29. 发明授权

US08672518B2 Low profile light and accessory kit for the same 有权
标题翻译：低调的灯和配件套件相同
公开(公告)号：US08672518B2
公开(公告)日：2014-03-18
申请号：US13476388
申请日：2012-05-21
申请人： Mark Penley Boomgaarden , Michael Balestracci , Rick LeClair , Wei Sun , David Henderson , Shane Sullivan
发明人： Mark Penley Boomgaarden , Michael Balestracci , Rick LeClair , Wei Sun , David Henderson , Shane Sullivan
IPC分类号： F21V29/00
CPC分类号： F21V29/773 , F21K9/20 , F21K9/235 , F21K9/238 , F21K9/62 , F21K9/64 , F21K9/69 , F21S8/026 , F21S8/033 , F21S8/04 , F21V7/0066 , F21V7/04 , F21V17/007 , F21V21/02 , F21V21/04 , F21V21/047 , F21V23/00 , F21V23/002 , F21V23/02 , F21V23/026 , F21V23/06 , F21V29/004 , F21V29/2212 , F21V29/503 , F21V29/70 , F21V29/71 , F21V29/713 , F21V29/777 , F21Y2101/00 , F21Y2101/02 , F21Y2105/10 , F21Y2115/10
摘要： A luminaire includes a heat spreader; a heat sink; an LED light source; a power supply; an electrical supply line having a first end connected to the power supply, and a second end connected to a plug-in connector; and, an optic securely retained relative to the heat spreader or heat sink. An accessory kit includes a first pre-wired jumper including a pair of insulated electrical wires having a first plug-in connector electrically connected at one end and an Edison base electrically connected at the other end; and/or, a second pre-wired jumper including a pair of insulated electrical wires having a second plug-in connector electrically connected at one end and unconnected wire ends at the other end. The plug-in connector of the first pre-wired jumper and the second pre-wired jumper are each configured to electrically engage with the plug-in connector of the electrical supply line.
摘要翻译：灯具包括散热器; 散热器 LED光源; 电源; 电源线，其具有连接到所述电源的第一端，以及连接到插入式连接器的第二端; 并且相对于散热器或散热器可靠地保持光学元件。附件套件包括第一预接线跳线，其包括一对绝缘电线，其具有在一端电连接的第一插入式连接器和在另一端电连接的爱迪生基座; 和/或第二预接线跳线，其包括一对绝缘电线，所述绝缘电线具有在一端电连接的第二插入式连接器，而在另一端电连接未连接的导线端。第一预接线跳线和第二预接线跳线的插入式连接器各自被配置为与电源线的插入式连接器电接合。

30. 发明授权

US08646942B2 LED luminaire 有权
标题翻译： LED灯具
公开(公告)号：US08646942B2
公开(公告)日：2014-02-11
申请号：US13041877
申请日：2011-03-07
申请人： Mark Penley Boomgaarden , Shane Sullivan , Ryan Chase Kelley , David Henderson
发明人： Mark Penley Boomgaarden , Shane Sullivan , Ryan Chase Kelley , David Henderson
IPC分类号： F21S4/00
CPC分类号： F21V29/004 , F21K9/23 , F21K9/238 , F21K9/60 , F21V3/02 , F21V3/06 , F21V7/0008 , F21V7/041 , F21V17/06 , F21V17/164 , F21V23/006 , F21V29/74 , F21V29/773 , F21V29/78 , F21V29/83 , F21V29/87 , F21V29/89 , F21Y2105/10 , F21Y2115/10
摘要： A luminaire includes an electrical base, an optic, and a heat sink disposed between the base and the optic. The lens has a first curved portion, a second curved portion and a third portion. An LED light source is coupled to the heat sink with LED modules arranged to direct light in the same direction. A frustoconical member having a reflective outer surface is disposed between the lens and the LED light source wherein the LED light source has LED modules disposed to emit at least a portion of light toward the reflective outer surface such that light is emitted with a substantially even luminous intensity in a 0°-135° zone.
摘要翻译：灯具包括设置在基座和光学元件之间的电气基座，光学元件和散热器。透镜具有第一弯曲部分，第二弯曲部分和第三部分。 LED光源通过布置成沿相同方向引导光的LED模块耦合到散热器。具有反射外表面的截头圆锥体构件设置在透镜和LED光源之间，其中LED光源具有LED模块，LED模块设置成朝向反射外表面发射至少一部分光，使得以大致均匀的发光强度在0°-135°区域。

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