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21. 发明授权

US08617205B2 Closure device 有权
标题翻译：封闭装置
公开(公告)号：US08617205B2
公开(公告)日：2013-12-31
申请号：US12813489
申请日：2010-06-10
申请人： Dusan Pavcnik , Kurt J. Tekulve , Michael D. Deckard
发明人： Dusan Pavcnik , Kurt J. Tekulve , Michael D. Deckard
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B10/06 , A61B90/39 , A61B2017/00243 , A61B2017/00526 , A61B2017/00575 , A61B2017/00584 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00623 , Y10T29/49826
摘要： A closure device for closing a bodily passageway is provided. The device includes first and second frames and first and second crossbars. A sheet of biocompatible material is attached to one or more of the frames. The first crossbar extends across the first frame and has terminal crossbar ends connectively linked to separate sites on the first frame; the second crossbar is similarly linked to the second frame. The crossbars are attached to each other at a connection point, and they are each configured to bend away from the connection point when the closure device is deployed to close a bodily passageway. A method of making the closure device is provided, as well as a method for closing a bodily passageway using such a device. Further, a closure device assembly is provided, including a closure device, a delivery catheter housing, and a delivery release member.
摘要翻译：提供了用于关闭身体通道的闭合装置。该装置包括第一和第二框架以及第一和第二横梁。一片生物相容性材料附着到一个或多个框架。第一横杆延伸穿过第一框架并且具有连接到第一框架上的分离位置的端子横杆端部; 第二横杆与第二框架类似地连接。十字杆在连接点处彼此附接，并且它们各自被配置成当关闭装置展开以便关闭身体通道时远离连接点弯曲。提供一种制造闭合装置的方法，以及使用这种装置关闭身体通道的方法。此外，提供了一种闭合装置组件，包括封闭装置，输送导管壳体和递送释放构件。

22. 发明授权

US08613763B2 Implantable vascular device 有权
标题翻译：植入式血管装置
公开(公告)号：US08613763B2
公开(公告)日：2013-12-24
申请号：US12258757
申请日：2008-10-27
申请人： Dusan Pavcnik , Frederick S. Keller , Josef Rosch , Thomas A. Osborne , Brian L. Bates , John A. DeFord , Christopher G. Dixon , Andrew K. Hoffa , Raymond B. Leonard, II , Joseph F. Obermiller
发明人： Dusan Pavcnik , Frederick S. Keller , Josef Rosch , Thomas A. Osborne , Brian L. Bates , John A. DeFord , Christopher G. Dixon , Andrew K. Hoffa , Raymond B. Leonard, II , Joseph F. Obermiller
IPC分类号： A61F2/06 , A61F2/24
CPC分类号： A61F2/01 , A61F2/2418 , A61F2/2475 , A61F2002/018 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0008 , A61F2230/001 , A61F2230/0023 , A61F2230/0026 , A61F2230/0054 , A61F2230/0058 , A61F2230/0095 , Y10S623/901
摘要： A multiple-sided medical device comprises a frame comprising wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration which a generally serpentine shape. The device is pushed from a delivery catheter into the lumen of a duct or vessel and may include one or more barbs for anchoring purposes. A full or partial covering of fabric or other flexible material such as DACRON, PTFE, or a collagen-based material such as small intestinal submucosa (SIS), may be sutured or attached to the frame to form an occlusion device, a stent graft, or an implantable, intraluminal valve such as for correcting incompetent veins in the lower legs and feet.
摘要翻译：多面医疗装置包括包括线或其它弹性材料并具有一系列弯曲和互连侧的框架。该装置具有扁平构型和第二折叠构造，其大致蛇形形状。该装置从输送导管推入管道或容器的内腔，并且可以包括用于锚定目的的一个或多个倒钩。织物或其他柔性材料如DACRON，PTFE或基于胶原的材料如小肠粘膜下层（SIS）的全部或部分覆盖物可以被缝合或附着到框架上以形成闭塞装置，支架移植物，或可植入的管腔内瓣膜，例如用于矫正小腿和脚部的无能力的静脉。

23. 发明申请

US20080215087A1 BODILY LUMEN CLOSURE APPARATUS AND METHOD 有权
标题翻译：身体闭合装置和方法
公开(公告)号：US20080215087A1
公开(公告)日：2008-09-04
申请号：US12109574
申请日：2008-04-25
申请人： Dusan Pavcnik , John Kaufman , Clay D. Fette
发明人： Dusan Pavcnik , John Kaufman , Clay D. Fette
IPC分类号： A61B17/12 , A61F6/20
CPC分类号： A61B17/0057 , A61B17/00234 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12118 , A61B17/1219 , A61B2017/00004 , A61B2017/00637 , A61B2017/00641 , A61B2017/00654 , A61B2017/00898 , A61F2/07 , A61F2/89 , A61F6/225 , A61F6/24 , A61F2002/061 , A61F2002/065 , A61F2002/077 , A61F2230/005
摘要： An absorbable and expandable closure member used to occlude or exclude a body lumen or cavity, such as a blood vessel, fallopian tube, duct, aneurysmal sac, etc., comprising a closure member comprising one of more sheets of a biomaterial that are rolled, stacked, or folded to form a multilayer construct of a generally cylindrical configuration for deployment through a delivery system, either as a singularly or part of a multiplicity of closure members. The biomaterial is derived from a source material, such as small intestinal submucosa or another remodelable material (e.g., an extracellular matrix) having properties for stimulating ingrowth of adjacent tissue into the biomaterial deployed within the bodily lumen. The closure member is deployed to the bodily lumen from a delivery sheath, cartridge, and/or over a inner guiding member, such as a wire guide or catheter.
摘要翻译：一种可吸收和可膨胀的封闭构件，其用于闭塞或排除体腔或腔体，例如血管，输卵管，导管，动脉瘤囊等，其包括封闭构件，该闭合构件包括多个生物材料片材中的一个，堆叠或折叠以形成大致圆柱形构造的多层构造，用于通过输送系统进行部署，作为单个或多个闭合构件的一部分。生物材料衍生自源材料，例如小肠粘膜下层或具有用于刺激相邻组织的向内生长进入体内部署的生物材料的特性的另一种可重塑材料（例如细胞外基质）。封闭构件从输送护套，药筒和/或内部引导构件（例如电线引导件或导管）部署到身体管腔。

24. 发明申请

US20050143807A1 Implantable vascular device comprising a bioabsorbable frame 审中-公开
标题翻译：可植入血管装置，其包括生物可吸收框架
公开(公告)号：US20050143807A1
公开(公告)日：2005-06-30
申请号：US10910490
申请日：2004-08-03
申请人： Dusan Pavcnik , Frederick Keller , Josef Rosch , Thomas Osborne , John Deford , Joseph Obermiller , Joe Roberts , Paul Amarant
发明人： Dusan Pavcnik , Frederick Keller , Josef Rosch , Thomas Osborne , John Deford , Joseph Obermiller , Joe Roberts , Paul Amarant
IPC分类号： A61F2/01 , A61F2/24 , A61F2/06
CPC分类号： A61F2/01 , A61F2/2418 , A61F2/2475 , A61F2002/018 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0008 , A61F2230/001 , A61F2230/0023 , A61F2230/0026 , A61F2230/0054 , A61F2230/0058 , A61F2230/0095 , Y10S623/901
摘要： A multiple-sided valve for implantation within a body vessel comprising a frame comprising a bioabsorbable material is provided. The devices can be pushed from a delivery catheter into the lumen of a duct or vessel and may include one or more barbs for anchoring purposes. A full or partial covering of fabric or other flexible material, or a bioabsorbable material, including a collagen-based material such as small intestinal submucosa (SIS), may be attached to the frame to form an occlusion device, a graft, or an implantable, intraluminal valve such as for correcting incompetent veins in the lower legs and feet.
摘要翻译：提供了用于植入体内容器的多侧阀，其包括包含生物可吸收材料的框架。这些装置可以从输送导管推入管道或容器的内腔，并且可以包括用于锚固目的的一个或多个倒钩。织物或其他柔性材料或包括基于胶原的材料如小肠粘膜下层（SIS）的生物可吸收材料的全部或部分覆盖物可以附接到框架上以形成闭塞装置，移植物或植入物，腔内瓣膜，如用于矫正小腿和脚部无力静脉。

25. 发明授权

US5643317A Closure prosthesis for transcatheter placement 失效
标题翻译：闭经假体用于经导管放置
公开(公告)号：US5643317A
公开(公告)日：1997-07-01
申请号：US244580
申请日：1994-05-27
申请人： Dusan Pavcnik , Sidney Wallace , Kenneth C. Wright
发明人： Dusan Pavcnik , Sidney Wallace , Kenneth C. Wright
IPC分类号： A61B17/00 , A61B17/12 , A61B17/08
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12109 , A61B17/12172 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606
摘要： A closure prosthesis and transcatheter delivery system includes a closure prosthesis for sealing across all opening of a fluid passageway within a living body. The closure prosthesis is a flexible disk including a flexible ring and diaphragm having a plurality of hollow flexible wire segments attached thereto. Delivery of the closure prosthesis is accomplished using a hollow sheath and a pusher catheter slidable within the sheath, wherein filaments are looped through the wire segments to releasably connect the disk to the pusher catheter. The disk is resiliently compressed within the sheath and, upon release therefrom, the disk resiliently expands into a larger, unrestrained shape. Tension applied to the filaments resiliently bends the wire segments so that they may be drawn through the opening of the defect. Upon releasing the filaments from the disk, the wire segments resiliently expand to trap the disk in place to seal across the opening.
摘要翻译： PCT No.PCT / US92 / 10141 Sec。 371日期：1994年5月27日 102（e）日期1994年5月27日PCT提交1992年11月25日PCT公布。公开号WO93 / 10714 PCT 日期1993年6月10日闭合假体和经导管递送系统包括用于密封活体内的流体通道的所有开口的闭合假体。闭合假体是包括柔性环和隔膜的柔性盘，其具有附接到其上的多个中空柔性线段。闭合假体的传送使用中空护套和在护套内可滑动的推动导管来实现，其中细丝环绕穿过线段以可释放地将盘连接到推动导管。盘在护套内被弹性地压缩，并且在从其释放时，盘弹性地膨胀成更大的，无限制的形状。应用于细丝的张力弹性地弯曲线段，使得它们可以被拉过缺陷的开口。当从盘释放细丝时，线段弹性地膨胀以将盘捕获到适当的位置以密封穿过开口。

26. 发明授权

US5350398A Self-expanding filter for percutaneous insertion 失效
标题翻译：用于经皮插入的自扩张过滤器
公开(公告)号：US5350398A
公开(公告)日：1994-09-27
申请号：US68594
申请日：1993-05-28
申请人： Dusan Pavcnik , Sidney Wallace , Kenneth C. Wright
发明人： Dusan Pavcnik , Sidney Wallace , Kenneth C. Wright
IPC分类号： A61F2/01 , A61F2/06 , A61M29/00
CPC分类号： A61F2/01 , A61F2002/011 , A61F2002/016 , A61F2002/8483 , A61F2230/0006 , A61F2230/0069
摘要： A flexible vena cava filter comprises a flexible stent having a plurality of flexible wire segments attached across the ends of the stent. The filter is resiliently compressible for percutaneous insertion into a fluid passageway and expands against the passageway upon placement therein. The filter includes different levels of filtration.
摘要翻译：柔性腔静脉过滤器包括柔性支架，其具有穿过支架的端部附接的多个柔性线段。过滤器是可弹性压缩的，用于经皮插入流体通道中并且在放置在其中时抵靠通道膨胀。过滤器包括不同级别的过滤。

27. 发明授权

US09023074B2 Multi-stage occlusion devices 有权
标题翻译：多级闭塞装置
公开(公告)号：US09023074B2
公开(公告)日：2015-05-05
申请号：US13461260
申请日：2012-05-01
申请人： Elizabeth Theobald , James R. Randolph , Dusan Pavcnik , Frederick Keller , Brad Shirley , Sean Chambers , Ram Paul , Rodney Thurman , Michael Deckard
发明人： Elizabeth Theobald , James R. Randolph , Dusan Pavcnik , Frederick Keller , Brad Shirley , Sean Chambers , Ram Paul , Rodney Thurman , Michael Deckard
IPC分类号： A61M29/00 , A61B17/12 , A61B17/00
CPC分类号： A61B17/1214 , A61B17/0057 , A61B2017/00597
摘要： An occlusion device has a covering attached to a support frame that includes a disc-shaped member and a crossbar that extends across a central opening defined by the disc-shaped member. The occlusion device has a first, or deployed, configuration in which the crossbar defines a curve that extends from the disc-shaped member, and a second, or resting, configuration in which the disc-shaped member and the crossbar lie substantially in a single plane. Each of the disc-shaped member and the crossbar include a core wire that extends through a lumen of a coil multiple times.
摘要翻译：闭塞装置具有附接到支撑框架的覆盖物，该支撑框架包括圆盘状构件和跨越由盘状构件限定的中心开口延伸的横杆。闭塞装置具有第一或部署的构造，其中横杆限定从盘形构件延伸的曲线，以及第二或静止构造，其中盘形构件和横杆基本上位于单个飞机圆盘状构件和横杆中的每一个都包括多次延伸通过线圈的内腔的芯线。

28. 发明授权

US08992598B2 Biomedical valve devices, support frames for use in such devices, and related methods 有权
标题翻译：生物医学阀门装置，用于这种装置的支撑框架及相关方法
公开(公告)号：US08992598B2
公开(公告)日：2015-03-31
申请号：US13602514
申请日：2012-09-04
申请人： Dusan Pavcnik
发明人： Dusan Pavcnik
IPC分类号： A61F2/24 , A61L27/50 , A61L27/36
CPC分类号： A61F2/2418 , A61F2/2475 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2220/0066 , A61F2220/0075 , A61L27/3625 , A61L27/507
摘要： Biomedical valve devices, support frames for use in such devices, methods of making such devices, and methods of treating animals, including humans, for valve-related conditions are described. The biomedical valve devices can includes a native tissue valve attached to a support frame or a tissue attached to a support frame in a manner to form a valve. The tissue valve or tissue can be autogenous to the animal being treated.
摘要翻译：描述了用于阀相关状况的生物医学阀装置，用于这种装置的支撑框架，制造这种装置的方法以及治疗包括人类在内的动物的方法。生物医学阀装置可以包括以形成阀的方式附接到支撑框架或附接到支撑框架的组织的天然组织瓣膜。组织瓣膜或组织可以与待治疗的动物自发生长。

29. 发明授权

US08257429B2 Biomedical valve devices, support frames for use in such devices, and related methods 有权
标题翻译：生物医学阀门装置，用于这种装置的支撑框架及相关方法
公开(公告)号：US08257429B2
公开(公告)日：2012-09-04
申请号：US11842363
申请日：2007-08-21
申请人： Dusan Pavcnik
发明人： Dusan Pavcnik
IPC分类号： A61F2/24 , A61F2/86
CPC分类号： A61F2/2418 , A61F2/2475 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2220/0066 , A61F2220/0075 , A61L27/3625 , A61L27/507
摘要： Biomedical valve devices, support frames for use in such devices, methods of making such devices, and methods of treating animals, including humans, for valve-related conditions are described. The biomedical valve devices can includes a native tissue valve attached to a support frame or a tissue attached to a support frame in a manner to form a valve. The tissue valve or tissue can be autogenous to the animal being treated.
摘要翻译：描述了用于阀相关状况的生物医学阀装置，用于这种装置的支撑框架，制造这种装置的方法以及治疗包括人类在内的动物的方法。生物医学阀装置可以包括以形成阀的方式附接到支撑框架或附接到支撑框架的组织的天然组织瓣膜。组织瓣膜或组织可以与待治疗的动物自发生长。

30. 发明授权

US07686842B2 Endovascular stent graft 有权
标题翻译：血管内支架移植
公开(公告)号：US07686842B2
公开(公告)日：2010-03-30
申请号：US09849044
申请日：2001-05-04
申请人： Dusan Pavcnik , Josef Rösch , Frederick S. Keller
发明人： Dusan Pavcnik , Josef Rösch , Frederick S. Keller
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/915 , A61F2002/072 , A61F2002/075
摘要： A stent graft (10) with a stent frame (12) having a plurality of stents (16) connected together with monofilament line (22). A covering (14) of collagen having an extracellular matrix (ECM), such as small intestine submucosa (SIS), is disposed through the inside and over the outside of the stent frame. The covering (14) is affixed to the stent frame (12) such as by being sutured onto the stent frame at the ends of the stent frame and also at the connections of the stent bodies, such as at eyelets (24).
摘要翻译：具有支架框架（12）的支架移植物（10）具有多个与单丝线（22）连接在一起的支架（16）。具有细胞外基质（ECM）的胶原蛋白（14）例如小肠粘膜下层（SIS）通过支架框架的内部和外侧设置。覆盖物（14）例如通过在支架框架的端部被缝合到支架框架上以及支架体（例如孔眼（24））的连接处而被固定到支架框架（12）上。

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