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21. 发明申请

US20140058375A1 HIGH RESOLUTION MAP AND ABLATE CATHETER 审中-公开
标题翻译：高分辨率地图和导线
公开(公告)号：US20140058375A1
公开(公告)日：2014-02-27
申请号：US13973631
申请日：2013-08-22
申请人： Boston Scientific Scimed, Inc.
发明人： Josef V. Koblish
IPC分类号： A61B18/18
CPC分类号： A61B18/18 , A61B18/1492 , A61B2017/00026 , A61B2017/00039 , A61B2017/00044 , A61B2017/00048 , A61B2018/00839
摘要： A medical system includes a medical probe including an elongated member having a distal end, a metallic electrode mounted to the distal end of the elongated member, and a plurality of microelectrodes embedded within, and electrically insulated from, the metallic electrode. A radio frequency (RF) ablation source is configured to deliver RF ablation energy to the metallic electrode. A filter circuit is electrically connected to the microelectrodes such that the filter circuit receives electrical signals from the microelectrodes. The filter circuit is configured to filter signal components induced by the RF ablation energy from the electrical signals. A mapping processor electrically is coupled to the filter circuit and configured to receive and process the filtered electrical signals.
摘要翻译：医疗系统包括医疗探针，其包括具有远端的细长构件，安装到细长构件的远端的金属电极以及嵌入在金属电极内并与其电绝缘的多个微电极。射频（RF）消融源被配置为将RF消融能量传递到金属电极。滤波器电路电连接到微电极，使得滤波器电路接收来自微电极的电信号。滤波器电路被配置为从电信号中滤除由RF消融能量引起的信号分量。电映射处理器电耦合到滤波器电路并且被配置为接收和处理经滤波的电信号。

22. 发明授权

US09872717B2 Balloon catheter with flexible electrode assemblies 有权
公开(公告)号：US09872717B2
公开(公告)日：2018-01-23
申请号：US14747702
申请日：2015-06-23
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： Robert F. Bencini , Frank Ingle , Josef V. Koblish , Rebecca Tin , James Mazzone , Byron Chun , David Lawrence
IPC分类号： A61B18/02 , A61B5/042 , A61B18/00
CPC分类号： A61B18/02 , A61B5/0422 , A61B2018/00017 , A61B2018/00023 , A61B2018/0022 , A61B2018/00714 , A61B2018/00791 , A61B2018/00797 , A61B2018/0212 , A61B2018/0262
摘要： In some implementations, a method of ablating body tissue includes (a) locating an inflatable balloon portion of a cryotherapy balloon catheter at a treatment site internal to a patient's body, and inflating the inflatable balloon portion; (b) employing electrodes that are disposed on an expandable surface of the inflatable balloon portion to electrically characterize body tissue at the treatment site; (c) ablating the body tissue by supplying a cryotherapy agent to the inflatable balloon portion to cool the body tissue to a therapeutic temperature; (d) employing the electrodes to determine whether the ablating caused desired electrical changes in the body tissue; and (e) repeating (c) and (d) when it is determined that the ablating did not cause the desired electrical changes.

23. 发明授权

US09687166B2 High resolution cardiac mapping electrode array catheter 有权
公开(公告)号：US09687166B2
公开(公告)日：2017-06-27
申请号：US14512065
申请日：2014-10-10
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： Raj Subramaniam , Josef V. Koblish
IPC分类号： A61B5/042 , A61B5/04 , A61B5/046 , A61B5/0464 , A61B6/12 , A61B18/14 , A61B5/00
CPC分类号： A61B5/0422 , A61B5/04011 , A61B5/046 , A61B5/0464 , A61B5/6859 , A61B6/12 , A61B18/1492
摘要： Devices, systems, and methods for performing a mapping procedure on body tissue are disclosed. An example mapping device for mapping a tissue surface includes an elongate shaft and an electrode assembly. The electrode assembly includes a plurality of splines and a plurality of electrodes disposed on at least some of the splines. The electrode assembly is capable of moving between a collapsed configuration and an expanded configuration. In the expanded configuration, the electrode assembly may have a generally planar structure.

24. 发明授权

US09211156B2 Map and ablate closed-loop cooled ablation catheter with flat tip 有权
标题翻译：绘制和消融具有平头的闭环冷却消融导管
公开(公告)号：US09211156B2
公开(公告)日：2015-12-15
申请号：US14029562
申请日：2013-09-17
申请人： Boston Scientific Scimed, Inc.
发明人： Isaac J. Kim , Zaya Tun , Josef V. Koblish , Minhchau N. Cao
IPC分类号： A61B5/042 , A61B18/14 , A61B5/00 , A61B18/18 , A61B18/12 , A61B5/04 , A61B18/00
CPC分类号： A61B18/1492 , A61B5/04012 , A61B5/0422 , A61B5/4836 , A61B18/1206 , A61B18/18 , A61B2018/00005 , A61B2018/00023 , A61B2018/00029 , A61B2018/00839
摘要： A system for performing mapping and ablation functions includes a catheter sized and shaped for vascular access. The catheter includes an elongate body extending between a proximal end and a distal end and having at least one inner fluid lumen. The catheter further includes a tip section positioned proximate to the distal end of the body. The tip section includes a proximal portion and a distal portion. The distal portion can have a distal end that can be substantially planar. The system also includes one or more electrode structures exposed at the tip section such that the one or more electrode structures disposed proximate the substantially planar distal end of the tip section.
摘要翻译：用于执行测绘和消融功能的系统包括尺寸和形状用于血管通路的导管。导管包括在近端和远端之间延伸并具有至少一个内部流体内腔的细长体。导管还包括靠近身体的远端设置的尖端部分。尖端部分包括近端部分和远端部分。远侧部分可以具有可以是基本上平面的远端。该系统还包括暴露在尖端部分处的一个或多个电极结构，使得一个或多个电极结构设置在尖端部分的基本平坦的远端附近。

25. 发明授权

US08792958B2 Mapping probe assembly with skived tube body frame 有权
标题翻译：用扫管管体框映射探头组件
公开(公告)号：US08792958B2
公开(公告)日：2014-07-29
申请号：US13894035
申请日：2013-05-14
申请人： Boston Scientific Scimed, Inc.
发明人： Isaac J. Kim , Josef V. Koblish
IPC分类号： A61B5/042
CPC分类号： A61B18/1492 , A61B5/0422 , A61B5/6856 , A61B2018/00839 , A61M25/0105 , A61M25/0136 , A61M25/0147 , A61M2025/0681
摘要： An embodiment of a mapping probe assembly includes a body frame with a lumen therein. The body frame includes a catheter shaft region, a loop section and a transition region between the catheter shaft region and a loop section. A plurality of mapping electrodes are attached around the loop section. Electrical conductors extend through the lumen of the body frame to the mapping electrodes. In some embodiments, the loop section is skived, where a portion of the body frame is removed toward the interior of the loop section. The loop section has a generally planar loop, and further has a loop center. In some embodiments, the catheter shaft has an alignment generally perpendicular to the loop section where the alignment of the catheter shaft is along a line that intersects the planar loop proximate to the loop center.
摘要翻译：映射探针组件的实施例包括其中具有内腔的主体框架。主体框架包括导管轴区域，环路部分和导管轴区域和环路部分之间的过渡区域。多个映射电极被安装在环路部分周围。电导体延伸穿过身体框架的内腔到映射电极。在一些实施例中，循环部分被切割，其中身体框架的一部分朝向环部分的内部移除。环路部分具有大致平面的环路，并且还具有环路中心。在一些实施例中，导管轴具有大致垂直于环部分的对准，其中导管轴的对准沿着与靠近环中心的平面环相交的线。

26. 发明授权

US08731631B2 Systems and methods for making and using medical ablation systems having mapping catheters with improved anchoring ability 有权
标题翻译：用于制造和使用具有改进的锚定能力的具有映射导管的医疗消融系统的系统和方法
公开(公告)号：US08731631B2
公开(公告)日：2014-05-20
申请号：US13770847
申请日：2013-02-19
申请人： Boston Scientific Scimed, Inc.
发明人： Isaac Kim , Josef V. Koblish , David McGee
IPC分类号： A61B5/042 , A61B18/02 , A61B18/14
CPC分类号： A61B18/02 , A61B5/0422 , A61B5/0538 , A61B5/4836 , A61B5/6853 , A61B5/6856 , A61B5/6857 , A61B18/1492 , A61B18/18 , A61B2017/00053 , A61B2017/00867 , A61B2018/00166 , A61B2018/0022 , A61B2018/00375 , A61B2018/00577 , A61B2018/00642 , A61B2018/00916 , A61B2018/0212 , A61B2018/1407
摘要： A mapping catheter includes an elongated body for inserting into patient vasculature. A distal end of the elongated body includes a distal portion that includes a plurality of electrodes, a proximal portion disposed proximal to the distal portion, and a reduced-dimension portion disposed between the proximal and distal portions. The distal end is formed, at least in part, from a memory shape material that bends into a preformed shape upon release from a confined space. The preformed shape includes a first loop formed, at least in part, by the distal portion. The first loop is transverse to a longitudinal axis of the proximal portion. The reduced-dimension portion is configured and arranged to bend such that the reduced-dimension section advances distally through the first loop when the first loop is held in a fixed position and a force is applied distally along the longitudinal axis of the proximal portion.
摘要翻译：映射导管包括用于插入患者脉管系统的细长体。细长主体的远端包括远端部分，其包括多个电极，靠近远端部分设置的近端部分和设置在近端部分和远端部分之间的缩小部分。远端至少部分地由从密闭空间释放时弯曲成预成形的记忆形状材料形成。预成型形状包括至少部分由远端部分形成的第一环。第一回路横向于近端部分的纵向轴线。减小尺寸部分被构造和布置成弯曲，使得当第一环保持在固定位置并且沿着近端部分的纵向轴线向远侧施加力时，缩小尺寸部分向远侧延伸穿过第一环。

27. 发明授权

US08700120B2 Multi-bend steerable mapping catheter 有权
标题翻译：多弯导向导管
公开(公告)号：US08700120B2
公开(公告)日：2014-04-15
申请号：US13864101
申请日：2013-04-16
申请人： Boston Scientific Scimed, Inc.
发明人： Josef V. Koblish
IPC分类号： A61B5/04
CPC分类号： A61M25/0147 , A61B5/042 , A61B5/0422 , A61B5/6852
摘要： An electrophysiology catheter introduced through the groin and inferior vena cava into the right side of the heart comprises an elongate flexible shaft having a steerable distal section and a prolapsing section located proximally of the distal section. The distal section is inserted into the coronary sinus and a back-steering force is applied to the catheter to anchor the distal section therein, after which the catheter is further advanced to prolapse the prolapsing section against the high right atrium. Electrical pathways in both the coronary sinus and the high right atrium are mapped using respective electrode pairs carried on the distal and prolapsing sections of the catheter.
摘要翻译：通过腹股沟和下腔静脉导入心脏的右侧的电生理学导管包括细长的柔性轴，其具有可操纵的远侧部分和位于远端部分的近侧的脱垂部分。将远端部分插入冠状窦中，并将后向转向力施加到导管上以将远端部分固定在其中，之后导管进一步前进以使脱垂部分抵靠高右心房脱垂。使用在导管的远端和脱垂部分上承载的各自的电极对来映射冠状窦和高右心房两者中的电通路。

28. 发明申请

US20130172742A1 ABLATION PROBE WITH ULTRASONIC IMAGING CAPABILITY 有权
标题翻译：具有超声影像能力的吸引探测器
公开(公告)号：US20130172742A1
公开(公告)日：2013-07-04
申请号：US13729685
申请日：2012-12-28
申请人： Boston Scientific Scimed, Inc.
发明人： Darrell L. Rankin , Josef V. Koblish , Szabolcs Deladi
IPC分类号： A61B18/14 , A61B18/12 , A61M5/00 , A61B8/08 , A61B8/12 , A61B8/00
CPC分类号： A61B18/1492 , A61B8/12 , A61B8/445 , A61B8/4477 , A61B8/5207 , A61B8/54 , A61B18/1206 , A61B2017/00106 , A61B2017/003 , A61B2018/00023 , A61B2018/00577 , A61B2018/00821 , A61B2018/00982 , A61B2090/3784 , A61B2090/3966 , A61B2217/007 , A61M5/00
摘要： Devices and systems for ultrasonically imaging anatomical structures and performing ablation therapy within the body are disclosed. A combined ablation and ultrasound imaging probe includes an ablation electrode tip including an ablation electrode configured for delivering ablation energy, and a number of ultrasonic imaging sensors configured for imaging the tissue surrounding the probe. The ultrasonic imaging sensors are supported within the interior of the tip via a tip insert, and deliver ultrasonic waves through acoustic openings formed through the tip. The tip insert separates an interior lumen within the tip into a proximal fluid chamber and a distal fluid chamber. During an ablation procedure, the ultrasonic imaging sensors can be tasked to generate a number of ultrasonic images that can be displayed on a user interface.
摘要翻译：公开了用于超声成像解剖结构并在体内进行消融治疗的装置和系统。组合消融和超声成像探头包括消融电极尖端，其包括被配置为递送消融能量的消融电极，以及多个超声成像传感器，其构造成用于使探针周围的组织成像。超声波成像传感器通过尖端插入件支撑在尖端的内部，并且通过穿过尖端形成的声学开口传送超声波。尖端插入物将尖端内的内腔分成近端流体腔和远侧流体腔。在消融过程中，可以使超声波成像传感器产生可以在用户界面上显示的多个超声波图像。

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