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21. 发明申请

US20060205759A1 Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives 失效
标题翻译：环烷基稠合吲哚，苯并噻吩，苯并呋喃和茚衍生物
公开(公告)号：US20060205759A1
公开(公告)日：2006-09-14
申请号：US11355452
申请日：2006-02-16
申请人： Annmarie Sabb , Robert Vogel , Gary Stack , Deborah Evrard , Amedeo Failli , Lalitha Krishnan , Anita Chan , Jianxin Ren , Charles Guinosso , Reinhardt Baudy , Jean Sze , Yanfang Li , Charles Stanton , Antonia Nikitenko
发明人： Annmarie Sabb , Robert Vogel , Gary Stack , Deborah Evrard , Amedeo Failli , Lalitha Krishnan , Anita Chan , Jianxin Ren , Charles Guinosso , Reinhardt Baudy , Jean Sze , Yanfang Li , Charles Stanton , Antonia Nikitenko
IPC分类号： A61K31/4745 , C07D491/02
CPC分类号： C07D209/88 , C07D233/76 , C07D491/04 , C07D493/04
摘要： The present invention provides cycloalkylfused indole, benzothiophene, benzofuran, and indene derivatives, and methods for using them to, for example, treat, prevent and/or ameliorate central nervous system diseases by antagonizing 5-HT1A receptors and modulating serotonin levels.
摘要翻译：本发明提供环烷基稠合的吲哚，苯并噻吩，苯并呋喃和茚衍生物，以及使用它们例如通过拮抗5-HT 1A受体来治疗，预防和/或改善中枢神经系统疾病的方法。并调节5-羟色胺水平。

22. 发明申请

US20070166000A1 System and method for generating trick mode streams 审中-公开
标题翻译：用于产生特技模式流的系统和方法
公开(公告)号：US20070166000A1
公开(公告)日：2007-07-19
申请号：US11069297
申请日：2005-03-01
申请人： Ramesh Nallur , Jianxin Ren , Hank Guo , Peter Chan , Ben Cook
发明人： Ramesh Nallur , Jianxin Ren , Hank Guo , Peter Chan , Ben Cook
IPC分类号： H04N5/91
CPC分类号： H04N21/2387 , H04N5/783 , H04N7/17336 , H04N21/2343
摘要： Disclosed are systems and methods for creating a trick mode stream. A digital home communication terminal (DHCT) comprises a network interface, a storage medium, at least one memory storing program code; and at least one processor programmed by at least the program code. The network interface is in communication with a second DHCT. The program code enables the DHCT to: select a first encoded picture frame from a recorded video stream on the storage medium; retrieve a first sequence of transport packets encapsulating the first picture frame; create a first transport packet containing a first client control packet associated with the first picture frame; and transmit, to a video decoder in the second DHCT, a trick mode stream comprising the first transport packet followed by the first sequence of transport packets. The first client control packet comprises the size of the first picture frame and a decoder command.
摘要翻译：公开了用于创建特技模式流的系统和方法。数字家庭通信终端（DHCT）包括网络接口，存储介质，至少一个存储程序代码的存储器; 以及至少一个处理器至少由程序代码编程。网络接口与第二个DHCT通信。程序代码使DHCT可以：从存储介质上记录的视频流中选择第一编码图像帧; 检索封装所述第一图像帧的第一传输分组序列; 创建包含与第一图片帧相关联的第一客户端控制分组的第一传输分组; 并且将所述第二DHCT中的视频解码器发送到包含所述第一传输分组的特技模式流，所述第一传输分组后跟所述第一传输分组序列。第一客户端控制分组包括第一图像帧的大小和解码器命令。

23. 发明申请

US20050209245A1 Process for preparing N-aryl-piperazine derivatives 审中-公开
标题翻译：制备N-芳基 - 哌嗪衍生物的方法
公开(公告)号：US20050209245A1
公开(公告)日：2005-09-22
申请号：US11082510
申请日：2005-03-17
申请人： Anita Chan , Jianxin Ren , Archana Sharma
发明人： Anita Chan , Jianxin Ren , Archana Sharma
IPC分类号： C07D405/12 , A61K31/496 , C07D43/02
CPC分类号： C07D405/12
摘要： Processes for preparing N-aryl-piperazine derivatives of formula I particularly (R)-4-cyano-N-[2-[4-(2,3-dihydro-1,4-benzodioxan-5-yl)-1-piperazinyl-propyl]-N-(2-pyridinyl)-benzamide, are disclosed. Compositions comprising N-aryl-piperazine derivatives and low levels of common impurities are also disclosed. In addition, products produced by the process are disclosed.
摘要翻译：制备式I的N-芳基 - 哌嗪衍生物的方法，特别是（R）-4-氰基-N- [2- [4-（2,3-二氢-1,4-苯并二恶烷-5-基）-1-哌嗪基丙基] -N-（2-吡啶基） - 苯甲酰胺。还公开了包含N-芳基 - 哌嗪衍生物和低水平常见杂质的组合物。此外，公开了通过该方法生产的产品。

24. 发明申请

US20090023903A1 PROCESS FOR THE PREPARATION OF TRIFLUOROALKYL-PHENYL AND HETEROCYCLIC SULFONAMIDES 审中-公开
标题翻译：制备三氟甲基苯酚和杂环磺酰胺的方法
公开(公告)号：US20090023903A1
公开(公告)日：2009-01-22
申请号：US12172486
申请日：2008-07-14
申请人： Terrence Joseph Connolly , Anita Wai-Yin Chan , Zhixian Ding , Mousumi Ghosh , Xinxu Shi , Jianxin Ren , Eric Hansen , Roger Farr , Michael MacEwan , Asaf Alimardanov , Antonia Nikitenko , John Potoski
发明人： Terrence Joseph Connolly , Anita Wai-Yin Chan , Zhixian Ding , Mousumi Ghosh , Xinxu Shi , Jianxin Ren , Eric Hansen , Roger Farr , Michael MacEwan , Asaf Alimardanov , Antonia Nikitenko , John Potoski
IPC分类号： C07C311/17 , C07C311/00 , C07D333/34 , C07D263/20 , C07C33/46 , C07D265/30 , C09B29/36
CPC分类号： C07D295/108 , C07D263/26 , C07D333/34
摘要： A novel trifluoroacetylating agent, i.e., N-trifluoroacetylmorpholine, is described. This reagent is useful in the preparation of phenyl and heterocyclic sulfonamide compounds. Methods are therefore described for preparing sulfonamide compounds of the following structure, wherein R1 and R2 are defined herein, using N-trifluoroacetylmorpholine. The sulfonamide compounds that may be prepared as described herein include 5-chloro-thiophene-2-sulfonic acid [(1S,2R)-2-(3,5-difluoro-phenyl)-3,3,3-trifluoro-1-hydroxymethyl-propyl]-amide using N-trifluoroacetylmorpholine.
摘要翻译：描述了一种新型的三氟乙酰化剂，即N-三氟乙酰基吗啉。该试剂可用于制备苯基和杂环磺酰胺化合物。因此，描述了制备以下结构的磺酰胺化合物的方法，其中R1和R2在本文中定义，使用N-三氟乙酰基吗啉。可以如本文所述制备的磺酰胺化合物包括5-氯 - 噻吩-2-磺酸[（1S，2R）-2-（3,5-二氟 - 苯基）-3,3,3-三氟-1- 羟甲基 - 丙基] - 酰胺，使用N-三氟乙酰基吗啉。

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