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    • 25. 发明公开
    • 민감성 피부 진단용 바이오 마커 및 이를 이용한 진단 키트
    • 민감성피부진단용바이오마커및이를이용한진단키트
    • KR1020140123032A
    • 2014-10-21
    • KR1020140124111
    • 2014-09-18
    • (주)아모레퍼시픽서울대학교산학협력단
    • 안수선김수정이은영노민수이태룡문성준김한곤은희철정진호김은주최원우
    • C12Q1/68G01N33/53
    • C12Q1/6844C12Q1/6813
    • Disclosed is a biomarker having the amount of gene expression be specifically increased or reduced for sensitive skin. The biomarker specific to sensitive skin is used in such a diagnostic kit for sensitive skin and a screening method of an abirritant. The biomarker for diagnosis of sensitive skin according to the present invention one or more gene selected from a group composed of HLA-C, TCEA1, IGHA1, TFRC, S100A8, LOC652128, SERPINB13, EHF, FLJ10781, TP63, CDH1, TNFRSF19, GM2A, FKBP5, PI3, PSPH, HORMAD1, SPRR2G, and ACTR2 or a group composed of KBTBD10, TTN, ACTA1, MYBPC1, MB, MYOZ1, TPM1, CA3, CASQ1, ENO3, RBP4, GYG2, PPP1R1A, PYGM, G0S2, NEB, H19, LIPE, PLIN, H19, GPAM, FABP4, CIDEC, LPL, PCK1, ADIPOQ, PDE3B, ACVR1C, LPL, FABP4, DKFZP761N09121, TNMD, ATP6V1B1, C8orf22, and CRISP3.
    • 公开了对敏感性皮肤具有特异性增加或减少的基因表达量的生物标志物。 敏感性皮肤特异性生物标志物用于这种用于敏感性皮肤的诊断试剂盒和中枢刺激剂的筛选方法。 根据本发明的用于诊断敏感性皮肤的生物标志物选自由HLA-C,TCEA1,IGHA1,TFRC,S100A8,LOC652128,SERPINB13,EHF,FLJ10781,TP63,CDH1,TNFRSF19,GM2A, FKBP5,PI3,PSPH,HORMAD1,SPRR2G和ACTR2或由KBTBD10,TTN,ACTA1,MYBPC1,MB,MYOZ1,TPM1,CA3,CASQ1,ENO3,RBP4,GYG2,PPP1R1A,PYGM,G0S2,NEB,H19 ,LIPE,PLIN,H19,GPAM,FABP4,CIDEC,LPL,PCK1,ADIPOQ,PDE3B,ACVR1C,LPL,FABP4,DKFZP761N09121,TNMD,ATP6V1B1,C8orf22和CRISP3。