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21. 发明申请

WO2009047663A2 SYSTEM FOR PROVIDING A METHOD FOR APPLYING A SKIN SEALANT HAVING A PHASE CHANGE VISUAL INDICATING COMPONENT 审中-公开
标题翻译：提供具有相变视觉指示组件的皮肤密封剂的方法的系统
公开(公告)号：WO2009047663A2
公开(公告)日：2009-04-16
申请号：PCT/IB2008053779
申请日：2008-09-17
申请人： KIMBERLY CLARK CO , MACDONALD JOHN GAVIN , SMITH MOLLY K , WEART ILONA F , SCHORR PHILLIP A
发明人： MACDONALD JOHN GAVIN , SMITH MOLLY K , WEART ILONA F , SCHORR PHILLIP A
IPC分类号： A61M35/00
CPC分类号： A61M35/003 , A61B2017/00495
摘要： A system for providing a method of sealing skin with a film forming polymer is provided. The system includes providing an at least two part applicator containing a sealant composition in one or more frangible containers, providing instructions for using the applicator associated therewith, where the method including moving at least one of said applicator parts from a first position to a second position and applying said sealant to skin. The composition has film former, a plasticizer and 3000 to 10000 ppm of a dye that changes color when is undergoes a phase change. The color change is visible to a human eye under normal light conditions. changing dyes may be used to indicate that the composition has dried. The dyes change color in response to the phase change, i.e., drying of the film former. The dye may be added either directly to the composition, incorporated into a sponge on an applicator through which the composition is dispensed and applied, applied separately or applied simultaneously from a separate reservoir. The amount of dye in the composition can be adjusted to provide a visual cue to the user of the application area and the extent of cure though should generally be in the range of 3000 to 10000 ppm.
摘要翻译：提供了一种用于提供用成膜聚合物密封皮肤的方法的系统。该系统包括在一个或多个易碎容器中提供含有密封剂组合物的至少两个部分施用器，其提供使用与其相关联的施用器的指导，其中所述方法包括将所述施用器部件中的至少一个从第一位置移动到第二位置并将所述密封剂施加到皮肤上。该组合物具有成膜剂，增塑剂和3000至10000ppm的染料，当发生相变时颜色变化。在正常光照条件下，人眼可见颜色变化。可以使用改变的染料来表示组合物已经干燥。染料根据相变而变色，即成膜剂的干燥。染料可以直接添加到组合物中，并入施用器上的海绵中，组合物通过其分配和施加，单独施用或从单独的储存器同时施用。可以调整组合物中的染料的量以向使用者提供视觉提示并且固化程度通常应在3000至10000ppm的范围内。

22. 发明申请

WO2009047655A2 PHASE CHANGE VISUAL INDICATING COMPOSITION 审中-公开
标题翻译：相变视觉指示组合物
公开(公告)号：WO2009047655A2
公开(公告)日：2009-04-16
申请号：PCT/IB2008/052825
申请日：2008-07-14
申请人： KIMBERLY-CLARK WORLDWIDE, INC. , MACDONALD, John, Gavin , SMITH, Molly, K. , WEART, Ilona, F. , SCHORR, Phillip, A.
发明人： MACDONALD, John, Gavin , SMITH, Molly, K. , WEART, Ilona, F. , SCHORR, Phillip, A.
IPC分类号： A61K8/00 , A61K49/00 , C12Q1/04
CPC分类号： A61K33/18 , A61L26/0061 , A61L26/0066 , A61L26/0071 , A61L2300/202 , A61L2300/404 , A61L2300/442
摘要： A skin sealant composition of a film former and a plasticizer and having various color changing dyes may be used to indicate that the composition has dried. The dyes change color in response to the phase change, i.e., drying of the film former. The dye may be added either directly to the composition, incorporated into a sponge on an applicator through which the composition is dispensed and applied, applied separately or applied simultaneously from a separate reservoir. The amount of dye in the composition can be adjusted to provide a visual cue to the user of the application area and the extent of cure though should generally be in the range of 3000 to 10000 ppm.
摘要翻译：可以使用成膜剂和增塑剂并且具有各种变色染料的表皮密封剂组合物来表示组合物已经干燥。染料响应相变而改变颜色，即干燥成膜剂。染料可以直接加入到组合物中，在涂抹器中加入海绵中，通过该涂抹器分配和施用组合物，分开施用或者从单独的储存器同时施用。可以调节组合物中染料的量，以向使用区域的使用者提供视觉提示，并且固化的程度通常应该在3000-10000ppm的范围内。

23. 发明申请

WO2008012709A2 THERMOCHROMIC COMPOSITIONS FOR SKIN APPLICATION 审中-公开
标题翻译：用于皮肤应用的热致变色组合物
公开(公告)号：WO2008012709A2
公开(公告)日：2008-01-31
申请号：PCT/IB2007/052701
申请日：2007-07-09
申请人： KIMBERLY-CLARK WORLDWIDE, INC. , MACDONALD, John Gavin , SCHORR, Phillip , AREHART, Kelly D. , BROWN, Tameka S. , LINTON, Lisa A. , OSLUND, Susan G.
发明人： MACDONALD, John Gavin , SCHORR, Phillip , AREHART, Kelly D. , BROWN, Tameka S. , LINTON, Lisa A. , OSLUND, Susan G.
CPC分类号： A61K8/11 , A61K9/0014 , A61K2800/412 , A61K2800/438 , A61Q17/005
摘要： Thermochromatic dyes may be added to compositions to be applied to skin in order to indicate where the composition is applied. After application to the skin the composition will turn from colored to colorless in a short period of time as its temperature rises in response to the curing reaction and to heat from the skin. The dyes are microencapsulated in order to avoid migration of the dye into the wound and to remain protected and functional. The dyes are selected such that they have a transition temperature between room temperature and that of the skin.
摘要翻译：可以将热色染料添加到要施用于皮肤的组合物中，以指示施用组合物的位置。施用于皮肤后，由于其温度随着固化反应而升高并从皮肤加热，所以组合物在短时间内将从有色变为无色。染料被微囊化以避免染料向伤口中迁移并保持保护和功能。选择染料使得它们具有在室温和皮肤之间的转变温度。

24. 发明申请

WO2007027859A1 ANTIMICROBIAL COMPOSITION 审中-公开
标题翻译：抗微生物组合物
公开(公告)号：WO2007027859A1
公开(公告)日：2007-03-08
申请号：PCT/US2006/033981
申请日：2006-08-31
申请人： KIMBERLY-CLARK WORLDWIDE, INC. , YAHIAOUI, Ali , SCHORR, Phillip, A. , HOFFMAN, Douglas, R. , KOENIG, David, William , SPENCER, Anthony S. , DOBSON, Angela, G.
发明人： YAHIAOUI, Ali , SCHORR, Phillip, A. , HOFFMAN, Douglas, R. , KOENIG, David, William , SPENCER, Anthony S. , DOBSON, Angela, G.
IPC分类号： C08K5/00
CPC分类号： C08K5/0058 , C08K5/31
摘要： An antimicrobial composition that involves a synergistic mixture in terms of active agents, of a primary antimicrobial agent, such as polyhexamethylene biguanide (PHMB), a secondary antimicrobial agent, and optionally an organic acid against various kinds of microbes is described. Various additional processing aids, such as alcohols and surfactants, may also be incorporated within the mixture. The composition allows one to use a significantly less concentration of individual constituent antimicrobial agents to achieve the same or a better degree of antimicrobial efficacy. The antimicrobial composition can be applied to the surface of almost any kind of substrate material, and can achieve a killing-efficacy of about 3 Log 10 reduction in microbes within 30 minutes under ambient conditions.
摘要翻译：描述了关于活性剂，主要抗微生物剂如聚六亚甲基双胍（PHMB），二次抗微生物剂和任选的针对各种微生物的有机酸的协同混合物的抗微生物组合物。各种其它加工助剂，如醇和表面活性剂，也可以掺入混合物中。该组合物允许使用显着较少浓度的单个成分抗微生物剂以达到相同或更好程度的抗微生物效力。抗微生物组合物可以应用于几乎任何种类的底物材料的表面，并且可以在环境条件下在30分钟内实现微生物中约3log 10/10的还原的杀伤效力。

25. 发明申请

WO2007027858A2 ANTIMICROBIAL TREATMENT OF NONWOVEN MATERIALS FOR INFECTION CONTROL 审中-公开
标题翻译：用于感染控制的非金属材料的抗微生物治疗
公开(公告)号：WO2007027858A2
公开(公告)日：2007-03-08
申请号：PCT/US2006/033980
申请日：2006-08-31
申请人： KIMBERLY-CLARK WORLDWIDE, INC. , SCHORR, Phillip, A. , HOFFMAN, Douglas, R. , KOENIG, David, William , SPENCER, Anthony, S. , YAHIAOUI, Ali , DOBSON, Angela, G.
发明人： SCHORR, Phillip, A. , HOFFMAN, Douglas, R. , KOENIG, David, William , SPENCER, Anthony, S. , YAHIAOUI, Ali , DOBSON, Angela, G.
CPC分类号： A01N47/44 , C08K5/0058 , D06M15/564 , D06M15/61 , D06M16/00 , A01N25/10 , A01N25/34 , A01N33/12 , A01N37/02 , A01N37/04 , A01N37/36 , A01N59/00 , A01N2300/00 , C08L21/00
摘要： A material substrate having at least part of a surface treated with an antimicrobial composition is described. The antimicrobial composition exhibits at least a 3 log 10 CFU reduction within a period of about 30 minutes after contact with various species of a broad spectrum of microorganisms. The substrate can be a nonwoven material that has good fluid barrier properties, which can be used in protective garments and sheets. Methods for manufacturing and imparting the antimicrobial treatment to the substrate are also provided.
摘要翻译：描述具有用抗微生物组合物处理的表面的至少一部分的材料基材。抗微生物组合物在与各种各样的微生物接触后约30分钟内显示至少3log 10 CFU还原。基材可以是具有良好的流体阻隔性的非织造材料，其可用于防护服和片材。还提供了制造和赋予对基材的抗微生物处理的方法。

26. 发明申请

WO2007027413A1 GERMICIDAL FACE MASK 审中-公开
标题翻译：杀菌面罩
公开(公告)号：WO2007027413A1
公开(公告)日：2007-03-08
申请号：PCT/US2006/031475
申请日：2006-08-11
申请人： KIMBERLY-CLARK WORLDWIDE, INC. , MATHIS, Michael, P. , BOWEN, Uyles, Woodrow, Jr. , STEINDORF, Eric, Clayton , SCHORR, Phillip, A. , DOBSON, Angela , YAHIAOUI, Ali , HOFFMAN, Douglas, R. , KOENIG, David , SPENCER, Anthony, Steve
发明人： MATHIS, Michael, P. , BOWEN, Uyles, Woodrow, Jr. , STEINDORF, Eric, Clayton , SCHORR, Phillip, A. , DOBSON, Angela , YAHIAOUI, Ali , HOFFMAN, Douglas, R. , KOENIG, David , SPENCER, Anthony, Steve
IPC分类号： A41D13/11
CPC分类号： B32B5/26 , A41D13/11 , A41D31/0083 , A41D2400/34 , A62B23/025 , B32B5/022 , B32B2262/0276 , B32B2437/00
摘要： A face mask (10) for reducing the amount of microbes to which a wearer is exposed is provided. The face mask includes a body portion (12) that has an outer layer (36) that has been treated with a germicidal agent in an effective amount. The layer may be a nonwoven fabric like a spunbond, meltblown or cof orm layer and may be a laminate of such layers . The face mask having such a germicidal treatment can result in a reduction in microbial activity as compared to another face mask, identical but for the germicidal agent.
摘要翻译：提供了一种用于减少穿着者暴露于其中的微生物数量的面罩（10）。面罩包括具有已经用有效量的杀菌剂处理的外层（36）的主体部分（12）。该层可以是无纺织物，如纺粘，熔喷或椰浆层，并且可以是这些层的层压体。具有这种杀菌处理的面罩可以导致与另一面罩相比的微生物活性降低，但是对于杀菌剂。

27. 发明申请

WO2005056912A1 METHOD OF TREATING SUBSTRATES WITH IONIC FLUOROPOLYMERS 审中-公开
标题翻译：用离子荧光体处理衬底的方法
公开(公告)号：WO2005056912A1
公开(公告)日：2005-06-23
申请号：PCT/US2004/026465
申请日：2004-08-16
申请人： KIMBERLY-CLARK WORLDWIDE, INC. , SNOWDEN, Hue, S. , POWERS, Michael, D. , SCHORR, Phillip, A.
发明人： SNOWDEN, Hue, S. , POWERS, Michael, D. , SCHORR, Phillip, A.
IPC分类号： D06M23/16
CPC分类号： D06N3/0011 , A61B46/40 , D06M11/13 , D06M15/277 , D06M15/576 , D06M15/657 , D06M23/16 , D06N3/0063 , D06N3/047 , D06N2209/041 , Y10T442/2164 , Y10T442/2279 , Y10T442/2418 , Y10T442/68
摘要： The present invention provides a method of treating a substrate to improve the alcohol repellency of the substrate while minimizing the effect on the hydrostatic head value of the substrate that includes contacting a substrate with a treatment solution that includes an ionic fluoropolymer, a monovalent salt, and essentially no antistatic agent or less than 0.05 weight percent by weight of an antistatic agent.
摘要翻译：本发明提供一种处理基材以改善基材的醇排斥性的方法，同时最小化对基材的静水压头值的影响，包括使基材与包含离子含氟聚合物，一价盐和基本上没有抗静电剂或小于0.05重量％的抗静电剂。

28. 发明申请

WO2005056911A1 METHOD OF TREATING NONWOVEN FABRICS WITH NON-IONIC FLUOROPOLYMERS 审中-公开
标题翻译：用非离子荧光体处理非织造布的方法
公开(公告)号：WO2005056911A1
公开(公告)日：2005-06-23
申请号：PCT/US2004/026462
申请日：2004-08-16
申请人： KIMBERLY-CLARK WORLDWIDE, INC. , SNOWDEN, Hue, S. , POWERS, Michael, D. , SCHORR, Phillip, A.
发明人： SNOWDEN, Hue, S. , POWERS, Michael, D. , SCHORR, Phillip, A.
IPC分类号： D06M15/277
CPC分类号： D06M15/277 , D06M15/576 , D06M15/657 , D06M23/16 , D06M2200/00 , D06M2200/10 , D06N3/0011 , D06N3/0059 , D06N3/0063 , D06N3/047 , D06N2209/046 , D06N2209/128 , Y10T442/20 , Y10T442/2049 , Y10T442/2057 , Y10T442/2066 , Y10T442/2098 , Y10T442/2164 , Y10T442/2418 , Y10T442/2451 , Y10T442/659 , Y10T442/66
摘要： The present invention provides a method of treating a nonwoven fabric to improve alcohol repellency that includes contacting a nonwoven fabric with an aqueous treatment solution that includes a non-ionic fluoropolymer and essentially no antistatic agent or less than 0.05 weight percent by weight of an antistatic agent. The present invention also provides a nonwoven fabric with improved alcohol repellency.
摘要翻译：本发明提供了一种处理无纺织物以提高拒水性的方法，其包括使非织造织物与包含非离子含氟聚合物的水性处理溶液接触，并且基本上不含抗静电剂或小于0.05重量％的抗静电剂。本发明还提供了具有改善的拒斥性的无纺织物。

29. 发明申请

WO2020168136A1 PORTABLE ELECTRICAL STIMULATION SYSTEM AND METHOD 审中-公开
公开(公告)号：WO2020168136A1
公开(公告)日：2020-08-20
申请号：PCT/US2020/018196
申请日：2020-02-13
申请人： AVENT, INC , ZOBKIW, Chris , KLIMOVITCH, Gleb , LIU, Wanzhan , CALDWELL, Ryan , SCHEPIS, Eric , SCHORR, Phillip, A. , SHAH, Jalpa
发明人： ZOBKIW, Chris , KLIMOVITCH, Gleb , LIU, Wanzhan , CALDWELL, Ryan , SCHEPIS, Eric , SCHORR, Phillip, A. , SHAH, Jalpa
IPC分类号： A61N1/36 , A61N1/02 , A61N1/05 , A61N1/06
摘要： The present disclosure is directed to a portable system and method for modulating targeted neural and non-neural tissue of a nervous system to block nerve conduction for the treatment of pain, A high-efficiency portable electrical stimulation system is provided that allows a user to carry the system and move around freely while continuously receiving therapy. The electronic control system is configured to deliver high-frequency electrical stimulation at a therapeutic level, for an intended duration (e.g., up to 24 hours or more) at a manageable and/or comfortable weight for a person, to the target nerve.

30. 发明申请

WO2013046071A1 ONE STEP CECOSTOMY 审中-公开
标题翻译：一步法
公开(公告)号：WO2013046071A1
公开(公告)日：2013-04-04
申请号：PCT/IB2012/054111
申请日：2012-08-13
申请人： KIMBERLY-CLARK WORLDWIDE, INC. , BAGWELL, Alison, S. , ESTES, Thomas, G. , FEASTER, Shawn, R. , REICHART, Emily, A. , SCHORR, Phillip, A. , STADELMAN, Jennifer, S. , TAI, Kok-Ming
发明人： BAGWELL, Alison, S. , ESTES, Thomas, G. , FEASTER, Shawn, R. , REICHART, Emily, A. , SCHORR, Phillip, A. , STADELMAN, Jennifer, S. , TAI, Kok-Ming
IPC分类号： A61F5/445 , A61M25/04 , A61M27/00 , A61M25/00 , A61M39/02 , A61J15/00 , A61F5/442
CPC分类号： A61F5/445 , A61F5/442 , A61F13/0203 , A61F2005/4455 , A61J15/0023 , A61J15/0038 , A61J15/0042 , A61J15/0057 , A61J15/0065 , A61J15/0069 , A61J15/0073 , A61M39/0247 , A61M2039/0255 , A61M2039/0261 , A61M2039/0282 , A61M2039/0291 , A61M2039/0297 , A61M2210/1064
摘要： The present disclosure describes a cecostomy tube (30) having a head (36) with an opening (42) and a valve. There is a flexible catheter (34) with a lumen (38) having proximal and distal ends, the proximal end of the catheter in fluid communication with the opening in the head, a portion of the catheter extending away from the head to define the distal end. There is a retainer (32) provided on the distal end of the catheter. The retainer can change shape from a first profile or configuration to a second profile, for example in response to contact with fluid, where the second profile is larger than the first profile and the second profile is adapted to retain the cecostomy tube in place in a body. The device may comprise a second lumen through which adhesive can be injected and delivered along the outside surface of the catheter. The device may be placed in a single, initial surgical operation.
摘要翻译：本公开描述了一种具有头部（36）的开孔管（30），其具有开口（42）和阀。存在具有近端和远端的内腔（38）的柔性导管（34），导管的近端与头部中的开口流体连通，导管的一部分远离头部延伸以限定远端结束。在导管的远端设置有保持器（32）。保持器可以将形状从第一轮廓或构造改变为第二轮廓，例如响应于与流体的接触，其中第二轮廓大于第一轮廓，并且第二轮廓适于将球囊切口管保持在适当位置身体。该装置可以包括第二内腔，粘合剂可以通过该第二内腔沿导管的外表面被注入和递送。该装置可以放置在单一的初始外科手术中。

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