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21. 发明申请

US20150119797A1 MOTION ACTIVATED SEPTUM PUNCTURING DRUG DELIVERY DEVICE 审中-公开
标题翻译：运动激活的冲击药物递送装置
公开(公告)号：US20150119797A1
公开(公告)日：2015-04-30
申请号：US14593041
申请日：2015-01-09
申请人： MEDIMOP Medical Projects Ltd.
发明人： Oz CABIRI
IPC分类号： A61M5/142 , A61M5/172 , A61M5/145
CPC分类号： A61M5/14248 , A61J1/1406 , A61M5/14244 , A61M5/1452 , A61M5/14566 , A61M5/158 , A61M5/172 , A61M5/283 , A61M5/3146 , A61M2005/14208 , A61M2005/14252 , A61M2005/14256 , A61M2005/14268 , A61M2005/14533 , A61M2005/14573 , A61M2005/1581 , A61M2005/247 , A61M2005/2474 , A61M2205/123
摘要： A method and apparatus are disclosed for delivery of a drug to a recipient. In some embodiments, the delivery apparatus may unseal a drug containing reservoir. In some embodiments, the delivery rate may be controlled and/or adjustable. Optionally the apparatus may be disposable. Optionally, the apparatus may have a low profile and/or be wearable and/or attachable to the recipient. Optionally, discharge of the drug and/or unsealing of the reservoir may be driven by a plunger moving parallel to the base of the apparatus. Optionally, the apparatus may release a hypodermic needle into the recipient. Optionally, release of the hypodermic needle may be in a direction non-parallel and/or orthogonal to the direction of movement of the plunger. Optionally, prior to release, the hypodermic needle may be preserved in an aseptic state by a needle opening septum sealing a needle opening. Optionally, upon release, the hypodermic needle may pierce the needle opening septum.
摘要翻译：公开了将药物递送到接受者的方法和装置。在一些实施方案中，递送装置可以开封含药物储存器。在一些实施例中，输送速率可以被控制和/或可调节。可选地，该装置可以是一次性的。可选地，该装置可以具有低轮廓和/或可佩戴和/或可附接到接收者。任选地，药物的排出和/或储存器的开封可以由平行于装置的底座移动的活塞驱动。可选地，该装置可将皮下注射针释放到受体中。任选地，皮下注射针的释放可以在与柱塞的移动方向不平行和/或正交的方向上。任选地，在释放之前，皮下注射针可以通过密封针孔的针头开口隔膜保持在无菌状态。任选地，在释放时，皮下注射针可以刺穿针头开口隔膜。

22. 发明申请

US20150112297A1 QUICK RELEASE VIAL ADAPTER 审中-公开
标题翻译：快速释放六角适配器
公开(公告)号：US20150112297A1
公开(公告)日：2015-04-23
申请号：US14391792
申请日：2013-04-10
申请人： MEDIMOP Medical Projects Ltd.
发明人： Nimrod Lev , Amir Lev
IPC分类号： A61J1/20
CPC分类号： A61J1/2089 , A61J1/201 , A61J1/2055 , A61J1/2096
摘要： Vial adapters including a skirt having a transverse directed top surface and a pair of opposite downward depending snap fit flex members each integrally formed with an inward directed ridge for telescopically snap fitting onto a vial opening and an upright finger grip extension. Manual inward urging of the pair of opposite finger grip extensions towards one another flexes the pair of opposite snap fit flex members at the top surface such that their pair of opposite inwardly directed ridges are outwardly urged from one another thereby releasing a previously snap fitted drug vial.
摘要翻译：小瓶适配器包括具有横向定向顶部表面的裙部和一对相对的向下依附的卡扣配合柔性构件，每个柔性构件一体地形成有向内指向的脊部，用于可伸缩地卡扣配合到小瓶开口和直立的手指伸出部。一对相对的手指握持部分的手动向内的推动朝向彼此弯曲，使得该对相对的卡扣配合柔性构件在顶部表面处弯曲，使得它们的一对相对的向内指向的脊彼此向外推动，由此释放先前卡扣的药物小瓶。

23. 发明申请

US20150088078A1 FLUID TRANSFER DEVICES HAVING CARTRIDGE PORT WITH CARTRIDGE EJECTION ARRANGEMENT 有权
标题翻译：带盒式喷射装置的流体传输装置
公开(公告)号：US20150088078A1
公开(公告)日：2015-03-26
申请号：US14385212
申请日：2013-04-07
申请人： MEDIMOP Medical Projects Ltd.
发明人： Nimrod Lev , Niv Ben Shalom
IPC分类号： A61M5/178 , A61J1/14 , A61J1/20
CPC分类号： A61M5/1782 , A61J1/062 , A61J1/1406 , A61J1/201 , A61J1/2013 , A61J1/2055 , A61J1/2089 , A61J1/2096
摘要： Fluid transfer devices for use in manual cartridge filling procedures for filling cartridges with liquid drug dosages from medicament containing vials. The fluid transfer devices include a double ended main body having a longitudinal axis, a vial port for telescopic receiving a drug vial and a cartridge port for slidingly receiving a leading cartridge end. The cartridge port includes a cartridge securing arrangement for releasably securing a leading cartridge end therein and a cartridge ejection arrangement for at least partially ejecting a cartridge therefrom for assisting manual sliding ejection of a filled cartridge. The cartridge port can include either a combined cartridge securing and ejection arrangement or a discrete cartridge securing arrangement and a discrete cartridge ejection arrangement.
摘要翻译：流体输送装置，用于手动滤筒填充程序，用于从含药物瓶中的液体药物剂量填充药筒。流体输送装置包括具有纵向轴线的双端主体，用于伸缩接收药物瓶的小瓶端口和用于滑动地接收引导盒端部的盒端口。盒式存储器端口包括用于将引导盒端部可释放地固定在其中的盒固定装置和用于至少部分地弹出盒的盒排出装置，用于辅助填充的盒的手动滑动排出。盒式存储器端口可以包括组合的盒固定和排出装置或分立的盒固定装置和分立的盒排出装置。

24. 发明申请

US20150032084A1 MOTION ACTIVATED SEPTUM PUNCTURING DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：US20150032084A1
公开(公告)日：2015-01-29
申请号：US14510846
申请日：2014-10-09
申请人： MEDIMOP Medical Projects Ltd.
发明人： Oz CABIRI
IPC分类号： A61M5/142 , A61M5/158 , A61M5/145
CPC分类号： A61M5/14248 , A61J1/1406 , A61M5/14244 , A61M5/1452 , A61M5/14566 , A61M5/158 , A61M5/172 , A61M5/283 , A61M5/3146 , A61M5/46 , A61M2005/14208 , A61M2005/14252 , A61M2005/14256 , A61M2005/14268 , A61M2005/14533 , A61M2005/14573 , A61M2005/1581 , A61M2005/247 , A61M2005/2474 , A61M2205/123
摘要： A method and apparatus are disclosed for delivery of a drug to a recipient. In some embodiments, the delivery apparatus may unseal a drug containing reservoir. In some embodiments, the delivery rate may be controlled and/or adjustable. Optionally the apparatus may be disposable. Optionally, the apparatus may have a low profile and/or be wearable and/or attachable to the recipient. Optionally, discharge of the drug and/or unsealing of the reservoir may be driven by a plunger moving parallel to the base of the apparatus. Optionally, the apparatus may release a hypodermic needle into the recipient. Optionally, release of the hypodermic needle may be in a direction non-parallel and/or orthogonal to the direction of movement of the plunger. Optionally, prior to release, the hypodermic needle may be preserved in an aseptic state by a needle opening septum sealing a needle opening. Optionally, upon release, the hypodermic needle may pierce the needle opening septum.

25. 发明申请

US20140174223A1 ANTI-ROTATION FEATURE FOR INFUSION PUMP CARTRIDGE 审中-公开
标题翻译：用于输液泵的抗旋转特征
公开(公告)号：US20140174223A1
公开(公告)日：2014-06-26
申请号：US14193692
申请日：2014-02-28
申请人： MEDIMOP Medical Projects Ltd.
发明人： Yossi GROSS , Oz CABIRI
IPC分类号： F16H25/12
CPC分类号： A61M5/31596 , A61M5/1413 , A61M5/14248 , A61M5/1452 , A61M5/1456 , A61M5/14566 , A61M5/158 , A61M5/16827 , A61M5/172 , A61M5/1723 , A61M5/3146 , A61M2005/14252 , A61M2005/1426 , A61M2005/14268 , A61M2005/14533 , A61M2005/31518 , A61M2205/3523 , A61M2205/3569 , F16H25/12 , Y10T74/18576
摘要： Apparatus is described for administering a substance to a subject. A vial contains the substance and a stopper is disposed within the vial and is slidably coupled to the vial. A first threaded element is (a) rotatable with respect to the vial and (b) substantially immobile proximally with respect to the vial during rotation of the first threaded element. A second threaded element is threadedly coupled to the first threaded element. At least a distal end of the second threaded element is substantially non-rotatable with respect to the vial, and the distal end of the second threaded element defines a coupling portion that couples the second threaded element to the stopper. The first threaded element, by rotating, linearly advances the stopper and at least the distal end of the second threaded element toward a distal end of the vial. Other embodiments are also described.
摘要翻译：描述了用于向受试者施用物质的装置。一个小瓶包含该物质，一个塞子设置在小瓶内并可滑动地连接到小瓶。第一螺纹元件是（a）相对于小瓶可旋转，并且（b）在第一螺纹元件的旋转期间相对于小瓶在近端基本上不可移动。第二螺纹元件螺纹连接到第一螺纹元件。至少第二螺纹元件的远端相对于小瓶基本上不可旋转，并且第二螺纹元件的远端限定将第二螺纹元件联接到止动件的联接部分。第一螺纹元件通过旋转线性地将止动件和至少第二螺纹元件的远端朝向小瓶的远端前进。还描述了其它实施例。

26. 发明申请

US20140128815A1 ADHESIVE STRUCTURE FOR MEDICAL DEVICE 审中-公开
标题翻译：医疗器械粘合结构
公开(公告)号：US20140128815A1
公开(公告)日：2014-05-08
申请号：US13667739
申请日：2012-11-02
申请人： MEDIMOP MEDICAL PROJECTS LTD.
发明人： Oz CABIRI , Reuven Y. FILMAN , Boris DEGTIAR
IPC分类号： A61M5/158
CPC分类号： A61M5/158 , A61M5/14248 , A61M2005/14252 , A61M2205/13
摘要： A variable flexibility adhesive system may adhere a surface of a medical infusion device to the skin of a user. The system may be configured to hold a location on the surface stationary with respect to a site on the user's skin. The system may include an adhesive substrate for adhering to the user and an interface where the substrate is held to the surface of the device. The interface may totally and/or partially surround the stationary location. A skirt of the substrate may totally and/or partially surround the interface. Parts of the skirt may be stiffened. Optional features may include tabs for activation of the adhesive and/or a location for peeling the infuser to away from the skin. Additionally or alternatively, the interface may have variable flexibility. Additionally or alternatively, the stiffener may include a plastic layer.
摘要翻译：可变柔性粘合剂系统可以将医用输液装置的表面粘附到使用者的皮肤上。该系统可以被配置为保持表面上相对于使用者皮肤上的部位静止的位置。该系统可以包括用于粘附到使用者的粘合剂基底和将基底保持在装置的表面上的界面。接口可以完全和/或部分地围绕固定位置。衬底的裙部可以完全和/或部分地围绕界面。裙子的一部分可能会变硬。可选特征可以包括用于激活粘合剂的标签和/或用于将浸渍器剥离离开皮肤的位置。另外或替代地，接口可以具有可变的灵活性。附加地或替代地，加强件可以包括塑料层。

27. 发明授权

US10398837B2 Sensing a status of an infuser based on sensing motor control and power input 有权
公开(公告)号：US10398837B2
公开(公告)日：2019-09-03
申请号：US15855340
申请日：2017-12-27
申请人： MEDIMOP Medical Projects Ltd.
发明人： Oz Cabiri , Reuven Y. Filman
IPC分类号： A61M5/172 , A61M5/168 , A61M5/142
摘要： A status of a battery operated infuser may be detected by measuring a controlled input parameter. The measurement may be used to determine a magnitude of the input parameter and a parameter of the control. For example, control of power input to a motor may be by pulse density modulation. An integral of current over time may serve as a measure of current magnitude and pulse density. The result of the integral may be used to determine the status of the injector. The status may include normal functions for example start of pumping and/or malfunctions such as occlusion or drive disengagement.

28. 发明授权

US10286151B2 Plunger with reduced leakage during storage 有权
公开(公告)号：US10286151B2
公开(公告)日：2019-05-14
申请号：US15054990
申请日：2016-02-26
申请人： MEDIMOP Medical Projects Ltd.
发明人： Oz Cabiri
IPC分类号： A61M5/315 , A61M5/31 , B65B3/00 , B65B3/04
摘要： A plunger seal for a drug delivery device may have a mobile and an enhanced sealing parked state. Optionally, the cartridge is stored with the plunger seal in the parked state. Optionally, drug discharge occurs with the plunger seal in the mobile state. For example in the parked state there may be increased normal force between the plunger seal and an inner wall of the cartridge. Optionally there is limited deformation of the plunger seal between the parked and mobile states. Optionally the plunger seal is biased to the parked state. Optionally, a distal force switches the plunger seal to the mobile state. For example, the plunger seal may have an inner cavity that is expanded radially by core. A biasing element optionally biases the core wedging it proximally to the parked state. A distal force on the core may push it distally to the mobile state.

29. 发明授权

US10285907B2 Dual vial adapter assemblages with quick release drug vial adapter for ensuring correct usage 有权
公开(公告)号：US10285907B2
公开(公告)日：2019-05-14
申请号：US15541242
申请日：2016-01-03
申请人： MEDIMOP Medical Projects Ltd.
发明人： Uri David , Mordechai Bukhman
IPC分类号： A61J1/20
摘要： Dual vial adapter assemblages similar to U.S. Pat. No. 6,558,365 to Zinger et al. and U.S. Pat. No. 8,752,598 to Denenburg et al. and including a quick release drug vial adapter with an upright finger grip extension pair oppositely for manually urging inwards towards one another for releasing same from a drug vial. The quick release drug vial adapter ensures correct usage of a dual vial adapter assemblage by preventing immediate removal of a drug vial adapter from a drug vial after forming a liquid drug therein thereby assisting a healthcare provider to follow an administration protocol requiring an initial aspiration of some liquid drug for immediate administration purposes to a patient prior to subsequent infusion of the liquid drug remainder.

30. 发明申请

US20180117248A1 SENSING A STATUS OF AN INFUSER BASED ON SENSING MOTOR CONTROL AND POWER INPUT 审中-公开
公开(公告)号：US20180117248A1
公开(公告)日：2018-05-03
申请号：US15855340
申请日：2017-12-27
申请人： MEDIMOP Medical Projects Ltd.
发明人： Oz CABIRI , Reuven Y. FILMAN
IPC分类号： A61M5/172 , A61M5/142 , A61M5/168
CPC分类号： A61M5/172 , A61M5/14244 , A61M5/16831 , A61M2005/16863 , A61M2205/70
摘要： A status of a battery operated infuser may be detected by measuring a controlled input parameter. The measurement may be used to determine a magnitude of the input parameter and a parameter of the control. For example, control of power input to a motor may be by pulse density modulation. An integral of current over time may serve as a measure of current magnitude and pulse density. The result of the integral may be used to determine the status of the injector. The status may include normal functions for example start of pumping and/or malfunctions such as occlusion or drive disengagement.

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