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21. 发明公开

KR1020030025063A 실크아미노산의 생산방법 有权
标题翻译：生产丝氨酸的方法
公开(公告)号：KR1020030025063A
公开(公告)日：2003-03-28
申请号：KR1020010057986
申请日：2001-09-19
申请人： 월드웨이(주)
发明人： 주국태 , 최갑규
IPC分类号： C07K1/12
CPC分类号： C07K1/12 , C07K14/43586
摘要： PURPOSE: A process for producing silk amino acids is provided, thereby the silk amino acids which can be stably used in foods and medicines can be cheaply produced. CONSTITUTION: The process for producing silk amino acids comprises the steps of: refining the cocoon and raw silk-thread waste; washing the refined cocoon products with water and removing water from them; drying the refined cocoon products; hydrolysis of the dried refined cocoon products; neutralizing the hydrolyzed refined cocoon products; removing color and smell from the neutralized refined cocoon products; filtering the color and smell-removed refined cocoon products; removing salts from the filtered refined cocoon products; concentrating the desalted refined cocoon products; and drying the concentrated refined cocoon products, wherein the neutralization process is carried out by neutralizing the hydrolyzed refined cocoon products to pH 9.2 to 9.3; and reverse neutralizing the neutralized refined cocoon products to pH 7.5.
摘要翻译：目的：提供丝氨基酸的制造方法，能够廉价地制造可稳定地用于食品和药品的丝氨基酸。构成：丝氨酸生产工艺包括以下步骤：精制茧丝和生丝丝废料; 用水清洗精制的茧产品并从中除去水分; 干燥精制茧产品; 水解干燥的精制茧产品; 中和水解的精制茧产品; 从中和的精制茧产品中除去颜色和气味; 过滤颜色和嗅觉去除精制茧产品; 从过滤的精制茧产品中除去盐; 浓缩脱盐精制茧产品; 并干燥浓缩的精制茧产品，其中中和过程通过将水解的精制茧产物中和至pH 9.2至9.3进行; 并将中和的精制茧产品反向中和至pH 7.5。

22. 发明授权

KR101236526B1 실크단백질 가수분해물을 포함하는 모발성장 촉진용 조성물 有权
标题翻译：含有丝胶蛋白水解产物的组合物用于加速头发生长
公开(公告)号：KR101236526B1
公开(公告)日：2013-03-20
申请号：KR1020120034348
申请日：2012-04-03
申请人： 월드웨이(주)
发明人： 임우택 , 김종식 , 김복희
IPC分类号： A23L1/305 , A23J3/30 , A61K38/01 , A61P17/14
CPC分类号： A23L33/18 , A23L33/175 , A23V2002/00 , A23V2200/318 , A23V2250/06 , A23V2250/55 , A61K38/012 , A61Q7/00
摘要： PURPOSE: A composition for the hair growth promotion is provided to promote the growth of hair through the transdermal application or the oral administration of an amino acid composition similar to the composition of the hair. CONSTITUTION: A food composition for the hair growth promotion includes silk protein hydrolysate obtained by enzyme hydrolysis, and the enzyme is one or more selected from a group of protease-P, protease-N, alcalase, and neutrase. The silk protein hydrolysate includes silk amino acid or silk peptide. The food composition for the hair growth promotion only includes the silk protein hydrolysate. [Reference numerals] (AA) Experimental group (1); (BB) Positive control group; (CC) Experimental group (2); (DD) Non-treated group; (EE) Experimental group (3)
摘要翻译：目的：提供用于头发生长促进的组合物，以通过透皮施用或口服施用类似于头发组成的氨基酸组合物促进头发的生长。构成：用于毛发生长促进的食品组合物包括通过酶水解获得的丝蛋白水解产物，并且该酶是选自蛋白酶-P，蛋白酶-N，alcalase和中性粒子的一种或多种。丝蛋白水解产物包括丝氨酸或丝肽。用于头发生长促进的食物组合物仅包括丝蛋白水解产物。（AA）实验组（1）; （BB）阳性对照组; （CC）实验组（2）; （DD）未处理组; （EE）实验组（3）

23. 发明授权

KR101173546B1 누에탈지번데기 가수분해물을 포함하는 항비만 조성물 및 이를 제조하는 방법 有权
标题翻译：含有FAT-REMOVING SILKWORM PUPA HYDROLYZATE的抗菌成分及其制造方法
公开(公告)号：KR101173546B1
公开(公告)日：2012-08-13
申请号：KR1020110082444
申请日：2011-08-18
申请人： 월드웨이(주) , 충북대학교 산학협력단
发明人： 임우택 , 김윤배 , 이정용 , 연성호 , 이진채 , 구교철 , 손현정 , 문정초
IPC分类号： A61K35/63 , A61K35/64 , A23L1/30 , A61K38/48
CPC分类号： A61K35/63 , A23L33/10 , A61K38/48
摘要： PURPOSE: An anti-obesity composition containing fat-removed silkworm pupa hydrolysate is provided to effectively treat obesity including overweight. CONSTITUTION: An anti-obesity composition contains fat-removed silkworm pupa hydrolysate. A pharmaceutical composition and food composition for preventing and treating obesity contains the hydrolysate. The hydrolysate is prepared by hydrolyzing the fat-removed silkworm pupa by alcalase 2.4L and protease N in order.
摘要翻译：目的：提供含有去脂蚕蛹水解产物的抗肥胖组合物，有效治疗肥胖，包括超重。构成：抗肥胖组合物含有去脂蚕蛹水解产物。用于预防和治疗肥胖症的药物组合物和食物组合物含有水解产物。水解产物通过依次通过alcalase 2.4L和蛋白酶N水解除去脂肪的蚕蛹来制备。

24. 发明授权

KR101120584B1 라우로일 실크 아미노산 및 라우로일 실크 펩타이드의 제조방법 有权
标题翻译：柠檬酸丝氨酸和柠檬酸丝胶蛋白的制备方法
公开(公告)号：KR101120584B1
公开(公告)日：2012-03-09
申请号：KR1020110018119
申请日：2011-02-28
申请人： 월드웨이(주)
发明人： 이정용 , 소원영 , 손현정
IPC分类号： C12P21/06 , C07K1/12 , C07K1/107 , C07K14/435
CPC分类号： C12P21/06 , A61K8/64 , A61Q7/00 , C07K1/107 , C07K14/43586
摘要： PURPOSE: A method for preparing N-acyl silk amino acids and N-acyl silk peptides is provided to synthesize the N-acyl silk amino acids/peptides of high yield with little by-products. CONSTITUTION: A method for preparing surfactant with moisturizing, emulsifying, and foaming ability comprises: a step of dissolving silk amino acids or silk peptides in water; a step of adding alkali solution to prepare an alkaline mixture; and a step of reacting the alkaline mixture with lauroyl chloride to prepare lauroyl silk amino acids or lauroyl silk peptides. The silk amino acids or peptides are prepared by solubilizing cocoon with neutral salt and hydrolyzing with an enzyme.
摘要翻译：目的：提供N-酰基丝氨基酸和N-酰基丝肽的制备方法，以少量副产物合成高产率的N-酰基丝氨基酸/肽。构成：具有保湿，乳化和发泡能力的表面活性剂的制备方法，其特征在于：将丝氨基酸或丝肽溶解于水中的步骤; 加入碱溶液制备碱性混合物的步骤; 以及使碱性混合物与月桂酰氯反应以制备月桂酰丝氨酸或月桂酰丝肽的步骤。丝氨酸或肽通过用中性盐溶解茧并用酶水解制备。

25. 发明授权

KR101040923B1 페피노 및 실크펩타이드를 유효성분으로 포함하는 간 기능 개선용 조성물 有权
标题翻译：用于改善其作为活性成分的PEPINO和SILKPEPTIDE的肝功能的组合物
公开(公告)号：KR101040923B1
公开(公告)日：2011-06-16
申请号：KR1020100063927
申请日：2010-07-02
申请人： 월드웨이(주)
发明人： 임우택 , 이정용 , 연성호 , 구교철
IPC分类号： A61K38/01 , A61K35/64 , A23L1/30 , A61K38/46
CPC分类号： A61K38/01 , A23L33/10 , A61K35/63 , A61K38/46
摘要： PURPOSE: A composition containing Solanum muricatum Ait. and silkpeptide for relieving hangover and improving liver function is provided. CONSTITUTION: A composition for preventing and treating liver damage contains Solanum muricatum Ait. Hydrolysate which is hydrolysed by pectinase, arabinase, or glucoamylase; and silk peptide in a weight ratio of 10:90-40:60 as an active ingredient. The composition is a food composition. A method for manufacturing the composition comprises: a step of hydrolyzing Solanum muricatum Ait. With pectinase, arabinase, or glucoamylase; and a step of adding the silk peptide to Solanum muricatum Ait. Hydrolysate.
摘要翻译：目的：含有茄子的组合物。并提供用于缓解宿醉和改善肝功能的丝肽。构成：用于预防和治疗肝损伤的组合物包含茄属（Solanum muricatum）。由果胶酶，阿拉伯糖酶或葡糖淀粉酶水解的水解产物; 和丝肽以10：90-40：60的重量比作为活性成分。组合物是食物组合物。一种制造该组合物的方法，包括：水解茄属（Solanum muricatum）的步骤。用果胶酶，阿拉伯糖酶或葡糖淀粉酶; 以及将丝肽加入到茄属（Solanum muricatum Ait）中的步骤。水解物。

26. 发明授权

KR100947547B1 실크 펩타이드를 유효성분으로 하는 당뇨 치료 또는 예방용 조성물 有权
标题翻译：包含用于预防和治疗糖尿病的丝胶蛋白的组合物
公开(公告)号：KR100947547B1
公开(公告)日：2010-03-12
申请号：KR1020090067532
申请日：2009-07-23
申请人： 월드웨이(주)
发明人： 서형주 , 임우택 , 이정용 , 연성호 , 이진채 , 오규철
IPC分类号： A61K35/64 , A61K38/02 , A61K38/04 , A61K38/48
CPC分类号： A61K38/06 , A61K38/05 , A61K35/63 , A61K38/02 , A61K38/04 , A61K38/48
摘要： PURPOSE: A composition containing a silk peptide as an active ingredient for preventing or treating diabetes is provided to reduce blood sugar and prevent change of organ weight. CONSTITUTION: A composition for preventing or treating diabetes contains anti-diabetes active material with Gly-Tyr-Gly sequence as an active ingredient. The silk peptide is extracted using a protease. The average molecular weight of the anti-diabetes is under 1000. The average molecular weight of the anti-diabetes is 200-400.
摘要翻译：目的：提供含有丝肽作为预防或治疗糖尿病的活性成分的组合物，以降低血糖并防止器官重量的变化。构成：用于预防或治疗糖尿病的组合物含有Gly-Tyr-Gly序列作为活性成分的抗糖尿病活性物质。使用蛋白酶提取丝肽。抗糖尿病的平均分子量低于1000.抗糖尿病的平均分子量为200-400。

27. 发明授权

KR100789405B1 실크티로신의 제조방법 有权
标题翻译：生产丝状酪氨酸的方法
公开(公告)号：KR100789405B1
公开(公告)日：2007-12-28
申请号：KR1020070066444
申请日：2007-07-03
申请人： 월드웨이(주)
发明人： 임우택 , 이정용 , 오규철
IPC分类号： C07K1/12 , C07K1/14
摘要： A method for preparing silk tyrosine is provided to recover tyrosine, which is generated during a silk amino acid preparing process, with producing the silk amino acid. A method for preparing silk tyrosine comprises the steps of: (a) hydrolyzing refined cut cocoons with HCl; (b) neutralizing the solution acidified by the HCl using an aqueous solution of NaOH to maintain the pH of 1.5-3.5; (c) removing impurities from the neutralized solution; (d) neutralizing the solution obtained from the step(c) using an aqueous solution of NaOH to maintain the pH of 6.0-8.0; (e) separating a silk amino acid ingredient and a tyrosine ingredient from the solution obtained from the step(d); and (f) dissolving the extracted tyrosine and purifying it.
摘要翻译：提供丝素酪氨酸的制备方法，以回收在丝氨酸制备过程中产生的酪氨酸，生产丝氨酸。制备丝素酪蛋白的方法包括以下步骤：（a）用HCl水解精制的切茧; （b）使用NaOH水溶液中和HCl酸化的溶液以保持pH为1.5-3.5; （c）从中和溶液中除去杂质; （d）使用NaOH水溶液中和由步骤（c）获得的溶液以保持pH为6.0-8.0; （e）从步骤（d）获得的溶液中分离丝氨基酸成分和酪氨酸成分; 和（f）溶解所提取的酪氨酸并进行纯化。

28. 发明公开

KR1020030025064A 세리신 회수방법 有权
标题翻译：恢复丝氨酸的方法
公开(公告)号：KR1020030025064A
公开(公告)日：2003-03-28
申请号：KR1020010057987
申请日：2001-09-19
申请人： 월드웨이(주)
发明人： 주국태 , 최갑규
IPC分类号： C07K1/34
CPC分类号： C07K1/34 , C07K14/43586
摘要： PURPOSE: A process for recovering sericin is provided, thereby the sericin can be recovered from the cocoon-refining waste, so that environmental pollution caused by the cocoon-refining waste can be prevented. CONSTITUTION: The process for recovering sericin comprises the steps of: collecting the cocoon-refining waste from a process for recovering silk amino acids from the cocoon and raw silk-thread waste; filtering the cocoon-refining waste with a microfilter to remove impurities; neutralizing the filtered cocoon-refining waste with hydrochloric acid; filtering the neutralized cocoon-refining waste with the microfilter; washing the filtered solids with distilled water to remove salts; and drying the filtered solids.
摘要翻译：目的：提供一种回收丝胶蛋白的方法，从而可以从茧精炼废物回收丝胶蛋白，从而可以防止茧精炼废物引起的环境污染。构成：回收丝胶的方法包括以下步骤：从茧丝和生丝丝废料中回收丝氨基酸的方法收集茧精炼废物; 用微过滤器过滤茧精炼废物以去除杂质; 用盐酸中和过滤的茧精炼废物; 用微型过滤器过滤中和的茧精炼废物; 用蒸馏水洗涤过滤的固体以除去盐; 并干燥过滤的固体。

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