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21. 发明申请

WO2019032725A1 PHOTOSYNTHETIC BIOREACTOR FOR THE CONVERSION OF ELECTRICITY AND FERTILIZER INTO BIOMASS 审中-公开
公开(公告)号：WO2019032725A1
公开(公告)日：2019-02-14
申请号：PCT/US2018/045842
申请日：2018-08-08
申请人： FORELIGH, INC.
发明人： FLYNN, Adam , MOFFITT, Julie
IPC分类号： C12M1/00 , C12M3/00 , C12N1/12
摘要： A photobioreactor for cultivation and/or propagation of a photosynthetic organism and associated systems/methods are disclosed herewith. The photobioreactor includes (1) a substantially spherical vessel having a wall defining an interior vessel volume; (2) a water- submersible system for converting electrical energy into electromagnetic radiation; (3) a temperature management system for circulating heat dispersal fluid into and out of the water-submersible system; and (4) a photobioreactor control system comprising a processor and a controller.

22. 发明申请

WO2019032643A1 SELF-EXECUTING AGENTS FOR GATHERING HEALTH INFORMATION BETWEEN TRUSTED PARTIES 审中-公开
公开(公告)号：WO2019032643A1
公开(公告)日：2019-02-14
申请号：PCT/US2018/045708
申请日：2018-08-08
申请人： QUIO TECHNOLOGIES, LLC
发明人： DAHMANI, Alexander
IPC分类号： G06F19/00 , G16H15/00 , G06Q20/10 , G06Q50/22 , G06Q50/24
摘要： Apparatuses, systems, methods, and computer readable media for processing performance-based healthcare payments are disclosed herein. In one implementation, a method includes receiving, by a processor of a computing device, a first indication of assent to terms of a contract from a first computing device associated with a first party to the contract, and receiving, by the processor, a second indication of assent to the terms of the contract from a second computing device associated with a second party to the contract. The method further includes receiving, by the processor, patient health data from a third computing device, determining, by the processor, that the patient health data fulfills a condition of the terms of the contract, and automatically executing, by the processor, the contract in response to determining that the patient health data fulfills the condition.

23. 发明申请

WO2018213663A1 COMPOSITIONS AND METHODS FOR LOWERING TRIGLYCERIDES IN A SUBJECT HAVING REDUCED KIDNEY FUNCTION 审中-公开
公开(公告)号：WO2018213663A1
公开(公告)日：2018-11-22
申请号：PCT/US2018/033318
申请日：2018-05-18
申请人： AMARIN PHARMACEUTICALS IRELAND LIMITED , PHILIP, Sephy
发明人： PHILIP, Sephy
IPC分类号： A61K31/37 , A61K31/557
摘要： In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject having reduced kidney function.

24. 发明申请

WO2018094037A1 ORAL THIN FILMS COMPRISING PLANT EXTRACTS AND METHODS OF MAKING AND USING SAME 审中-公开
公开(公告)号：WO2018094037A1
公开(公告)日：2018-05-24
申请号：PCT/US2017/062001
申请日：2017-11-16
申请人： F6 PHARMA, INC.
发明人： HAMMELL, Dana, Carmel , STINCHCOMB, Audra , SHAH, Nihar
IPC分类号： A61K9/70 , A61K31/352 , A61K36/185
摘要： The present disclosure provides compositions comprising cannabidiol and methods of making and using same.

25. 发明申请

WO2018064444A1 MULTIVALENT PNEUMOCOCCAL VACCINE COMPOSITIONS COMPRISING POLYSACCHARIDE-PROTEIN CONJUGATES 审中-公开
标题翻译：含多糖 - 蛋白质缀合物的多价肺炎球菌疫苗组合物
公开(公告)号：WO2018064444A1
公开(公告)日：2018-04-05
申请号：PCT/US2017/054237
申请日：2017-09-29
申请人： BIOLOGICAL E LIMITED , MATUR, Ramesh, Venkat , MANTENA, Narender, Dev
发明人： MATUR, Ramesh, Venkat , MANTENA, Narender, Dev , SRIRAMAN, Rajan , CHAKKA, Deviprasanna , SUREDDI, Satyam, Naidu , BURKI, Rajendar , GANTI, Sreenivasa, Rao , DATLA, Mahima
IPC分类号： A61K39/09 , A61K39/385 , A61K39/39 , A61P31/04 , A61K39/00
摘要： The present disclosure relates to multivalent pneumococcal vaccine compositions comprising capsular pneumococcal polysaccharide serotypes each individually conjugated to carrier proteins. When conjugated, the combination of the capsular pneumococcal polysaccharide serotype and the carrier protein is referred to herein as a polysaccharide-protein conjugate. The pneumococcal vaccine compositions may further comprise one or more of the following; a pharmaceutically acceptable carrier, a pharmaceutically acceptable diluent, a buffer, a preservative, a stabilizer, an adjuvant, and/or a lyophilization excipient. Methods of making and administering the pneumococcal vaccine compositions described herein are also provided.
摘要翻译：本发明涉及多价肺炎球菌疫苗组合物，其包含各自独立缀合至载体蛋白的荚膜肺炎球菌多糖血清型。当缀合时，荚膜肺炎球菌多糖血清型和载体蛋白的组合在本文中称为多糖 - 蛋白质缀合物。肺炎球菌疫苗组合物可进一步包含一种或多种以下物质; 可药用载体，可药用稀释剂，缓冲剂，防腐剂，稳定剂，佐剂和/或冻干赋形剂。还提供了制造和施用本文所述的肺炎球菌疫苗组合物的方法。

26. 发明申请

WO2016164431A1 AUTOMATED SPECIMEN DEPOSITION SYSTEMS AND ASSOCIATED METHODS 审中-公开
标题翻译：自动样本沉积系统及相关方法
公开(公告)号：WO2016164431A1
公开(公告)日：2016-10-13
申请号：PCT/US2016/026174
申请日：2016-04-06
申请人： NANOCYTOMICS, LLC , NORTHWESTERN UNIVERSITY
发明人： CZARNECKI, Jarema , DERBAS, Justin , ROZHOK, Sergey , SUBRAMANIAN, Hariharan , VISWANATHAN, Parvathi
IPC分类号： B05D5/00
CPC分类号： G01N35/00029 , G01N1/312 , G01N35/00871 , G01N35/1011 , G01N2001/317 , G01N2035/00138 , G01N2035/00168 , G01N2035/00881
摘要： Systems and methods that enable automated spray deposition of biological specimens carried on microscope slides are described herein. Aspects of the technology are directed, for example, to automated specimen deposition systems and methods of generating high-quality, reproducible specimen-bearing microscope slides in automated processing systems.
摘要翻译：本文描述了能够自动喷雾沉积显微镜载玻片上的生物样品的系统和方法。该技术的方面涉及例如自动化样品沉积系统和在自动化处理系统中产生高质量，可再现的载体显微镜载玻片的方法。

27. 发明申请

WO2016140949A1 METHODS OF REDUCING OR PREVENTING OXIDATIVE MODIFICATION OF MEMBRANE POLYUNSATURATED FATTY ACIDS 审中-公开
标题翻译：减少或防止膜聚氨酯脂肪酸氧化改性的方法
公开(公告)号：WO2016140949A1
公开(公告)日：2016-09-09
申请号：PCT/US2016/020217
申请日：2016-03-01
申请人： AMARIN PHARMACEUTICALS IRELAND LIMITED , MASON, Richard, Preston
发明人： MASON, Richard, Preston
IPC分类号： A01N37/00
CPC分类号： A61K31/202 , A01N37/00 , A61K9/4858 , G01N33/92
摘要： In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of reducing or preventing membrane cholesterol domain formation in a subject, the method comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
摘要翻译：在各种实施方案中，本发明提供治疗和/或预防心血管相关疾病的方法，特别是减少或预防受试者中膜胆固醇结构域形成的方法，所述方法包括向有需要的受试者施用药物组合物包含二十碳五烯酸或其衍生物。

28. 发明申请

WO2016069639A1 LP(A) SUBFORM SIZE IDENTIFICATION BY CAPILLARY ISOTEACHOPHORESIS ELECTROPHORESIS WITH LASER-INDUCED-FLUORESCENCE 审中-公开
标题翻译： LP（A）通过毛细管电泳鉴定的尺寸标识具有激光诱导荧光
公开(公告)号：WO2016069639A1
公开(公告)日：2016-05-06
申请号：PCT/US2015/057641
申请日：2015-10-27
申请人： TRUE HEALTH DIAGNOSTICS, LLC
发明人： GUADAGNO, Philip , BELLIN, Erin, Grace, Summers
IPC分类号： G01N33/92
CPC分类号： G01N33/92 , G01N27/447
摘要： The application describes methods for determining the concentration and/or particle number of a lipoprotein(a) subform in a biological sample using capillary isotachophoresis laser induced fluorescence (CE-ITP-LIF) and compositional analysis of lipoprotein(a) particles. The ability to measure the concentration and/or particle number of a lipoprotein(a) subform in a biological sample provides a useful diagnostic tool for assessing cardiovascular risk in a subject.
摘要翻译：本申请描述了使用毛细血管等电泳激光诱导荧光（CE-ITP-LIF）和脂蛋白（a）颗粒的组成分析来确定生物样品中脂蛋白（a）亚型的浓度和/或粒子数的方法。测量生物样品中脂蛋白（a）亚型的浓度和/或粒子数量的能力为评估受试者的心血管风险提供了有用的诊断工具。

29. 发明申请

WO2016065021A1 LIPOPROTEIN PARTICLE NUMBER FROM MEASUREMENTS OF LIPOPROTEIN PARTICLE PHOSPHOLIPID CONCENTRATION IN LIPOPROTEIN PARTICLE MEMBRANE BILAYER 审中-公开
标题翻译：脂蛋白颗粒数量测定脂蛋白颗粒磷脂浓度在脂蛋白颗粒膜双层中的测定
公开(公告)号：WO2016065021A1
公开(公告)日：2016-04-28
申请号：PCT/US2015/056689
申请日：2015-10-21
申请人： TRUE HEALTH DIAGNOSTICS, LLC
发明人： GUADAGNO, Philip , BELLIN, Erin Grace, Summers , HARRIS, William, S. , DEVANUR, Deepika , HASSARD, Stuart
IPC分类号： G01N33/92
CPC分类号： G01N33/92 , G01N21/6402 , G01N21/6428 , G01N2021/6439
摘要： This application describes a method for measuring the molar concentrations of lipoprotein particles and lipoprotein subclass particles in bodily fluid by Multipixel Capillary Isotachophoresis Laser Induced Fluorescence (MPCE-ITP-LIF) and compositional analysis of spherical lipoprotein particles. The ability to measure several kinds of lipoproteins and particles in one unified system provides a useful diagnostic tool for predicting the risk of developing metabolic diseases such as cardiovascular disease and cardiodiabetes.
摘要翻译：本申请描述了一种通过Multipixel毛细管等速电泳激光诱导荧光（MPCE-ITP-LIF）和球形脂蛋白颗粒的组成分析来测量体液中脂蛋白颗粒和脂蛋白亚类颗粒的摩尔浓度的方法。在一个统一系统中测量几种脂蛋白和颗粒的能力为预测发展代谢性疾病如心血管疾病和心血管疾病的风险提供了有用的诊断工具。

30. 发明申请

WO2016004349A1 EVAPORATOR AND METHODS OF USING SAME 审中-公开
标题翻译：蒸发器及其使用方法
公开(公告)号：WO2016004349A1
公开(公告)日：2016-01-07
申请号：PCT/US2015/039056
申请日：2015-07-02
申请人： RICOTTA, Gesualdo
发明人： RICOTTA, Gesualdo
IPC分类号： F25B43/00
CPC分类号： F25B39/02 , F25B40/02 , F25B2500/18
摘要： An evaporator and methods of using the same are described herein. A vapor- compression refrigeration apparatus in accordance with an embodiment of the present technology utilizes a fluid refrigerant and can include a compressor, a condenser, an expansion device and an evaporator arranged in succession and in fluid communication within a closed loop in order to circulate the fluid refrigerant. The apparatus can include at least one line within the closed loop in operable communication with the condenser for reducing temperature of at least a portion of the fluid refrigerant coming from the condenser prior to the fluid refrigerant entering the expansion device.
摘要翻译：蒸发器及其使用方法在本文中描述。根据本技术的实施例的蒸气压缩式制冷装置利用流体制冷剂，并且可以包括压缩机，冷凝器，膨胀装置和蒸发器，其在闭合回路内连续布置并且流体连通，以便循环流体制冷剂。该装置可以包括在闭环内的至少一条线路，其与冷凝器可操作地连通，用于在流体制冷剂进入膨胀装置之前降低来自冷凝器的流体制冷剂的至少一部分的温度。

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