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21. 发明专利

CA2168066A1 TREATMENT OF HYPERTENSION AND CONGESTIVE HEART FAILURE 未知
公开(公告)号：CA2168066A1
公开(公告)日：1996-08-09
申请号：CA2168066
申请日：1996-01-25
申请人： POWELL JAMES R , SEYMOUR ANDREA ANN , TRIPPODO NICK C
发明人： POWELL JAMES R , SEYMOUR ANDREA ANN , TRIPPODO NICK C
IPC分类号： C12N9/99 , A61K31/16 , A61K31/19 , A61K31/195 , A61K31/198 , A61K31/20 , A61K31/215 , A61K31/23 , A61K31/41 , A61K31/415 , A61K31/535 , A61K31/54 , A61K31/55 , A61K45/06 , A61P9/00 , A61P9/12 , A61P43/00 , C07C323/52 , C07C323/56 , C07D223/12 , C07D403/10 , C07D498/04 , C07D513/04 , A61K38/05
摘要： Hypertension and/or congestive heart failure are treated with the combination of the angiotensin II antagonist 2-butyl-6,7,8,9-tetrahydro-3-¢¢2'-(1H-tetrazol-5-yl)¢1,1'-biphenyl!-4-yl!methyl!-1,3-diazaspiro¢4.4!nonan-4-one and a selective neutral endopeptidase inhibitor or a dual acting neutral endopeptidase inhibitor.

22. 发明专利

ZA957399B Electromagnetic induction suspension and horizontal switching system for a vehicle on a planar guideway 未知
公开(公告)号：ZA957399B
公开(公告)日：1996-06-03
申请号：ZA957399
申请日：1995-09-04
申请人： POWELL JAMES R , DANBY GORDON T , MORENA JOHN
发明人： POWELL JAMES R , DANBY GORDON T , MORENA JOHN
IPC分类号： B60G20060101 , B60K20060101 , B60L20060101 , B61B20060101 , B61F20060101 , B61J20060101 , H01F20060101 , B60G , B60K , B60L , B61B , B61F , B61J , H01F

23. 发明专利

AU3651501A Advanced vitrification system filling process 未知
公开(公告)号：AU3651501A
公开(公告)日：2001-11-12
申请号：AU3651501
申请日：2001-01-24
申请人： POWELL JAMES R , REICH MORRIS
发明人： POWELL JAMES R , REICH MORRIS
IPC分类号： C03B5/00 , C03B5/02 , C03B5/06 , G21F9/30 , G21F9/00
摘要： A method of filling a canister with vitrified waste starting with a waste, such as high-level radioactive waste, that is cooler than its melting point. Waste is added incrementally to a canister forming a column of waste capable of being separated into an upper zone and a lower zone. The minimum height of the column is defined such that the waste in the lower zone can be dried and melted while maintaining the waste in the upper zone below its melting point. The maximum height of the column is such that the upper zone remains porous enough to permit evolved gases from the lower zone to flow through the upper zone and out of the canister. Heat is applied to the waste in the lower zone to first dry then to raise and maintain its temperature to a target temperature above the melting point of the waste. Then the heat is applied to a new lower zone above the melted waste and the process of adding, drying and melting the waste continues upward in the canister until the entire canister is filled and the entire contents are melted and maintained at the target temperature for the desired period. Cooling of the melted waste takes place incrementally from the bottom of the canister to the top, or across the entire canister surface area, forming a vitrified product.

24. 发明专利

ZA953338B Electromagnetic induction ground vehicle levitation guideway 未知
公开(公告)号：ZA953338B
公开(公告)日：1996-01-09
申请号：ZA953338
申请日：1995-04-25
申请人： POWELL JAMES R , DANBY GORDON T , MORENA JOHN
发明人： POWELL JAMES R , DANBY GORDON T , MORENA JOHN
IPC分类号： B60L13/06 , B60L13/08 , B60L13/10 , B61B13/08 , E01B25/30 , E01B , B61B , B61F , H01F

25. 发明专利

ZA9503338B Electromagnetic induction ground vehicle levitation guideway 未知
公开(公告)号：ZA9503338B
公开(公告)日：1996-01-09
申请号：ZA9503338
申请日：1995-04-25
申请人： POWELL JAMES R , DANBY GORDON T , MORENA JOHN
发明人： POWELL JAMES R , DANBY GORDON T , MORENA JOHN
IPC分类号： B60L13/06 , B60L13/08 , B60L13/10 , B61B13/08 , E01B25/30 , E01B , B61B , B61F , H01F
CPC分类号： E01B25/305 , B60L13/06 , B60L13/08 , B60L13/10 , B60L2200/26 , B60L2220/14 , B61B13/08 , Y02T30/30

26. 发明专利

AU2394095A Electromagnetic induction ground vehicle levitation guideway 未知
公开(公告)号：AU2394095A
公开(公告)日：1995-11-16
申请号：AU2394095
申请日：1995-04-21
申请人： DANBY GORDON T , MORENA JOHN , POWELL JAMES R
发明人： POWELL JAMES R , DANBY GORDON T , MORENA JOHN
IPC分类号： B60L13/06 , B60L13/08 , B60L13/10 , B61B13/08 , E01B25/30

27. 发明专利

CA2327079A1 SYSTEM AND METHOD FOR MAGNETIC LEVITATION GUIDEWAY EMPLACEMENT ON CONVENTIONAL RAILROAD LINE INSTALLATIONS 未知
公开(公告)号：CA2327079A1
公开(公告)日：1999-10-14
申请号：CA2327079
申请日：1999-03-29
申请人： DANBY GORDON T , POWELL JAMES R
发明人： DANBY GORDON T , POWELL JAMES R
IPC分类号： B60L13/04 , E01B25/30 , B60L13/03 , B60L13/10 , E01B25/00
摘要： The maglev guideway is to be constructed on railroad ties of existing rail lines so that the rail lines can be used by both maglev vehicles and conventional trains. A plurality of support bars are mounted on the rail ties, and a plurality of guideway panels mounted on the support bars. Each of the guideway panels has vertical lift and stability windings for providing vertical lift, pitch and rolls stability to the maglev vehicle, and preferably also has lateral stability windings and linear synchronous motor windings. A protective cover sheet can be installed on the guideway panel, and the support bars can be pre-assembled by mounting them onto a registration grid. The guideway panel can also have a plurality of slots for accommodating threaded fasteners for mounting the guideway panel to the support bars.

28. 发明申请

WO2002061131A2 HUMAN SINGLE NUCLEOTIDE POLYMORPHISMS 审中-公开
标题翻译：人类单核多糖多态性
公开(公告)号：WO2002061131A2
公开(公告)日：2002-08-08
申请号：PCT/US2001/047235
申请日：2001-12-03
申请人： BRISTOL-MYERS SQUIBB COMPANY , TSUCHIHASHI, Zenta , HUI, Lester , ZERBA, Kim, E. , MA-EDMONDS, Manling , PERRONE, Mark, H. , SWANSON, Brian, N. , POWELL, James, R.
发明人： TSUCHIHASHI, Zenta , HUI, Lester , ZERBA, Kim, E. , MA-EDMONDS, Manling , PERRONE, Mark, H. , SWANSON, Brian, N. , POWELL, James, R.
IPC分类号： C12Q1/68
CPC分类号： C12N9/6445 , C07K14/705 , C07K14/81 , C07K14/8121 , C12N9/48 , C12Q1/6883 , C12Q2600/156 , C12Y304/11009 , C12Y304/21034
摘要： The invention provides polynucleotides and polypeptides corresponding to novel gene sequences associated with the incidence of cardiovascular disorders. The invention also provides polynucleotide fragments corresponding to the genomic and/or coding regions of these genes which comprise at least one polymorphic site per fragment. Allele-specific primers and probes which hybridize to these regions, and/or which comprise at least one polymorphic site are also provided. The polynucleotides, primers, and probes of the present invention are useful in phenotype correlations, paternity testing, medicine, and genetic analysis. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders, particularly cardiovascular diseases related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
摘要翻译：本发明提供对应于与心血管疾病发病相关的新基因序列的多核苷酸和多肽。本发明还提供对应于这些基因的基因组和/或编码区的多核苷酸片段，其包含每个片段至少一个多态性位点。还提供了与这些区域杂交的等位基因特异性引物和探针，和/或其包含至少一个多态性位点。本发明的多核苷酸，引物和探针可用于表型相关性，亲子鉴定，药物和遗传分析。还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。本发明还涉及将这些新型多肽应用于诊断，治疗和/或预防各种疾病和/或病症，特别是与这些多肽相关的心血管疾病的诊断和治疗方法。本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。

29. 发明申请

WO02061131A3 HUMAN SINGLE NUCLEOTIDE POLYMORPHISMS 审中-公开
标题翻译：人类单核多糖多态性
公开(公告)号：WO02061131A3
公开(公告)日：2003-06-19
申请号：PCT/US0147235
申请日：2001-12-03
申请人： SQUIBB BRISTOL MYERS CO , TSUCHIHASHI ZENTA , HUI LESTER , ZERBA KIM E , MA-EDMONDS MANLING , PERRONE MARK H , SWANSON BRIAN N , POWELL JAMES R
发明人： TSUCHIHASHI ZENTA , HUI LESTER , ZERBA KIM E , MA-EDMONDS MANLING , PERRONE MARK H , SWANSON BRIAN N , POWELL JAMES R
IPC分类号： C07K14/705 , C07K14/81 , C12N9/48 , C12N9/64 , C12Q1/68 , C07K14/47
CPC分类号： C12N9/6445 , C07K14/705 , C07K14/81 , C07K14/8121 , C12N9/48 , C12Q1/6883 , C12Q2600/156 , C12Y304/11009 , C12Y304/21034
摘要： The invention provides polynucleotides and polypeptides corresponding to novel gene sequences associated with the incidence of cardiovascular disorders. The invention also provides polynucleotide fragments corresponding to the genomic and/or coding regions of these genes which comprise at least one polymorphic site per fragment. Allele-specific primers and probes which hybridize to these regions, and/or which comprise at least one polymorphic site are also provided. The polynucleotides, primers, and probes of the present invention are useful in phenotype correlations, paternity testing, medicine, and genetic analysis. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders, particularly cardiovascular diseases related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
摘要翻译：本发明提供对应于与心血管疾病发病相关的新基因序列的多核苷酸和多肽。本发明还提供对应于这些基因的基因组和/或编码区的多核苷酸片段，其包含每个片段至少一个多态性位点。还提供了与这些区域杂交的等位基因特异性引物和探针，和/或其包含至少一个多态性位点。本发明的多核苷酸，引物和探针可用于表型相关性，亲子鉴定，药物和遗传分析。还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。本发明还涉及将这些新型多肽应用于诊断，治疗和/或预防各种疾病和/或病症，特别是与这些多肽相关的心血管疾病的诊断和治疗方法。本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。

30. 发明申请

WO02091392B1 WASTE VITRIFICATION PROCESS (AVS) AND MELTING PROCESS 审中-公开
标题翻译：废物处理过程（AVS）和熔化过程
公开(公告)号：WO02091392B1
公开(公告)日：2004-05-13
申请号：PCT/US0214159
申请日：2002-05-06
申请人： POWELL JAMES R , REICH MORRIS
发明人： POWELL JAMES R , REICH MORRIS
IPC分类号： B09B3/00 , C03B5/00 , C03B5/02 , C03B5/08 , G21F9/30
CPC分类号： G21F9/305 , B09B3/0075 , C03B5/005 , C03B5/021 , C03B5/08 , G21F9/308 , Y02P40/52
摘要： For the technical field of waste vitrification, an improved process for in-canister vitrification in a disposable canister with a vitrified product while minimizing leachability, product crystallization, volatilization of waste, foaming and container corrosion. Waste (50) is added to a disposable canister from the top. Radiant energy (40) is added to the space above the waste in the canister to form a pool of melted waste (60) at the bottom of the canister. The temperature of the melted waste decreases with increasing depth of the waste in the canister permitting the formation of a solidified product (70) below the melt pool. The process continues until the disposable canister is filled, then all heating is stopped and the disposable canister allowed to cool to ambient temperature.
摘要翻译：对于废玻璃化技术领域而言，提供了一种改进的一次性罐中带有玻璃化产品的容器内玻璃化过程，同时使可浸出性，产物结晶，废物挥发，发泡和容器腐蚀最小化。废物（50）从顶部添加到一次性罐中。辐射能量（40）被添加到罐中废物上方的空间中，以在罐的底部形成熔化废物池（60）。熔化的废物的温度随着罐中废物深度的增加而降低，从而允许在熔池下方形成固化产物（70）。该过程持续进行，直到一次性滤罐被填充，然后停止所有加热并允许一次性滤筒冷却至环境温度。

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