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    • 14. 发明申请
    • Enzymes cooated with ionic liquid
    • 酶与离子液体结合
    • US20040087462A1
    • 2004-05-06
    • US10471190
    • 2003-09-10
    • Mahn-Joo KimJae Kwan Lee
    • C12S009/00
    • C12P41/003C12N9/20C12N9/96
    • Disclosed is an ionic liquid-coated enzyme, wherein the ionic liquid is an organic salt which presents as a liquid phase at a temperature of about 150null C. or below. The ionic liquid-coated enzyme according to the present invention remarkbly improves enzyme functions, such as enantioselectivity and stability, when the enzyme which may be lipase is coated with an ionic liquid. Further, even in the case of when the ionic liquid-coated enzyme is reused, the enantiomeric excess, enantioselectivity, and activity are not degenerated. The coated enzyme is usable as a catalyst for providing a chiral intermediate required in the synthesis of chiral pesticides, medicines, natural chemicals, and so on.
    • 公开了一种离子液体包被的酶,其中离子液体是在约150℃或更低的温度下作为液相呈现的有机盐。 根据本发明的离子液体包被的酶,当可用脂肪酶的酶用离子液体包被时,显着提高了酶功能,如对映选择性和稳定性。 此外,即使在重新使用离子液体包被的酶的情况下,对映体过量,对映选择性和活性也不会退化。 涂覆的酶可用作提供合成手性农药,药物,天然化学品等所需的手性中间体的催化剂。