专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明申请

WO1992018614A1 AUTOINDUCER 审中-公开
标题翻译：自诱导物
公开(公告)号：WO1992018614A1
公开(公告)日：1992-10-29
申请号：PCT/GB1992000713
申请日：1992-04-16
申请人： THE UNIVERSITY OF NOTTINGHAM , BYCROFT, Barrie, Walsham , WILLIAMS, Paul , STEWART, Gordon, Sidney, Anderson, Birnie , CHHABRA, Siri, Ram , STEAD, Paul , WINSON, Michael, Kenneth , HILL, Philip, John , REES, Catherine, Elizabeth, Dunn , BAINTON, Nigel, John
发明人： THE UNIVERSITY OF NOTTINGHAM
IPC分类号： C12N01/38
CPC分类号： C07D307/33 , C12N1/38 , C12N15/67 , C12Q1/04
摘要： The compound N-( beta -ketocaproyl)L-homoserine lactone is shown to be an autoinducer that enhances gene expression in a wide variety of microorganisms. Use can be made of this property for diagnostic purposes, e.g. when gene expression causes bioluminescence or antibiotic production, or to promote bacterial growth. The invention claims use for these purposes of the compound and analogues of formula (1) where n is 2 or 3, each of X and Y is O, S or NH, and R is optionally-substituted C1-C12 alkyl or acyl. Some of these are also claimed as new compounds.
摘要翻译：化合物N-（β-酮己基）L-高丝氨酸内酯被证明是增强多种微生物中基因表达的自动诱导剂。可以使用此属性进行诊断，例如当基因表达导致生物发光或抗生素生产，或促进细菌生长。本发明要求用于这些目的的化合物和式（1）的类似物，其中n为2或3，X和Y各自为O，S或NH，R为任选取代的C 1 -C 12烷基或酰基。其中一些也被称为新化合物。

12. 发明申请

WO1997025411A1 A BIO-ENHANCER 审中-公开
标题翻译：生物增强剂
公开(公告)号：WO1997025411A1
公开(公告)日：1997-07-17
申请号：PCT/IB1997000010
申请日：1997-01-10
申请人： HENDERSON, Garth, M.
IPC分类号： C12N01/38
CPC分类号： C12N1/38
摘要： There is disclosed a bio-enhancing composition comprising a carbohydrate and saponin, preferably comprising yucca extract, for the acceleration of bacterial metabolism. This is particularly useful in the acceleration of bacterial metabolism in the breakdown of organic waste. There is also provided a method of stimulating microorganism metabolism and the use of the composition for such stimulation.
摘要翻译：公开了一种生物增强组合物，其包含碳水化合物和皂角苷，优选含有丝兰提取物，用于加速细菌代谢。这在有机废物分解中加速细菌代谢特别有用。还提供了一种刺激微生物代谢和使用该组合物用于这种刺激的方法。

13. 发明申请

WO1993023527A1 PROCESS FOR USING IRON CHELATORS AS SELECTIVE GROWTH SUPPLEMENTS FOR MICRO-ORGANISMS 审中-公开
标题翻译： PROCEDURE铁螯合剂AS选择性生长补充剂微生物中的应用
公开(公告)号：WO1993023527A1
公开(公告)日：1993-11-25
申请号：PCT/DE1993000138
申请日：1993-02-17
申请人： REISSBRODT, Rolf , RABSCH, Wolfgang
IPC分类号： C12N01/38
CPC分类号： C12Q1/045 , C12N1/38
摘要： The shortage of available iron for the growth of micro-organisms adversely, affects cultivation from materials to be examined like foodstuffs, medico-microbiological samples and from materials to be examined from the environment. The methods currently used capture such micro-organisms and add to them the more extensive characteristics needed for epidemiological research are material and time-consuming and give limited results. This applies especially to the cultivation of salmonella from food samples, which has not yet been successful enough to cover salmonelloses. The addition of iron chelators (microbial siderophores or synthetic iron chelators) as a growth supplement to the material to be examined, and/or the enriching and selective culture substances which can be used by the micro-organisms for their iron supply, makes possible a significant improvement in the cultivation or reisolation of the micro-organisms, both quantitatively (increasing sensitivity) and qualitatively (increasing selectivity). The addition of such iron chelators to micro-organism cultures makes product control possible in bio-technological and genetic engineering processes. The fields of application are medical microbiology, food microbiology, environmental microbial research, biotechnology and genetic engineering. A special field is the improvement of sensibility and selectivity in the cultivation of salmonella investigation materials by the addition of ferrioxamine siderophores, especially ferrioxamine G.

14. 发明申请

WO1987005626A1 PRODUCTION OF PROTEINS BY CELL CULTURE 审中-公开
标题翻译：通过细胞培养生产蛋白质
公开(公告)号：WO1987005626A1
公开(公告)日：1987-09-24
申请号：PCT/GB1987000173
申请日：1987-03-13
申请人： CELLTECH LIMITED , FIELD, Raymond, Paul
发明人： CELLTECH LIMITED
IPC分类号： C12N01/38
CPC分类号： C12N9/6459 , C07K14/52 , C07K14/61 , C07K16/00 , C07K16/065 , C12N1/38 , C12N5/163 , C12N2500/36 , C12Y304/21069
摘要： Increased yields of proteins are obtained by culturing genetically engineered or hybridoma cells, which constitutively produce the proteins, in the presence of chemical agents which enhance production of the proteins. The agents are employed at concentrations which enhance production of the proteins but do not substantially decrease cell growth rate or significantly reduce cell viability. The agents include alkanoic acids and salts thereof. The proteins include recombinant proteins and immunoglobulins.

15. 发明公开

EP0214564A3 Process for the preparation of proteins with a determined N-terminal structure with the aid of procaryotes 失效
标题翻译：用确定的N末端结构制备蛋白质的方法与助产程序
公开(公告)号：EP0214564A3
公开(公告)日：1988-08-31
申请号：EP86111946
申请日：1986-08-29
申请人： BASF Aktiengesellschaft
发明人： Blohm, Dietmar, Dr. , Martin, Christoph, Dr. , Hillen, Heinz, Dr. , Marcinowski, Stefan, Dr.
IPC分类号： C12N01/38 , C12P21/02
CPC分类号： C12N1/38 , C07K14/525
摘要： Verfahren zur Herstellung von Proteinen durch Züchtung gegebenenfalls gentechnologisch veränderter prokaryotischer Mikroorganismen und Gewin nung des Zielproteins aus der Biomasse, wobei das gewünschte Protein am N-terminalen Ende hinsichtlich der An- oder Abwesenheit der Aminosäure Methionin dadurch definiert wird, daß man die Züchtung in Gegenwart einer definierten Konzentration an Mangan- oder anderen Schwermetallionen vornimmt.
摘要翻译：通过培养原生细菌来制备蛋白质，原核微生物在适当的情况下经历遗传操作，目标蛋白质是从生物质获得的，所需蛋白质在N末端被定义为存在或不存在氨基通过在规定浓度的锰或其它重金属离子的存在下进行培养来进行酸性甲硫氨酸。

16. 发明公开

EP0177957A3 Expression of biologically active platelet derived growth factor analogs in eucaryotic cells 有权转让
标题翻译：生物活性板衍生生长因子模拟在真核细胞中的表达
公开(公告)号：EP0177957A3
公开(公告)日：1988-02-03
申请号：EP85112852
申请日：1985-10-10
申请人： ZYMOGENETICS, INC.
发明人： Murray, Mark Joseph , Kelly, James Darrel
IPC分类号： C12N15/00 , C07H21/04 , C12N01/16 , C12N05/00 , C12N01/38
CPC分类号： C07K14/005 , A61K38/00 , C07K14/49 , C07K2319/00 , C07K2319/02 , C07K2319/036 , C07K2319/75 , C12N15/81 , C12N2740/11022 , Y10S930/12 , Y10S930/221
摘要： Biologically active PDGF analogs expressed in eucaryotic cells are disclosed. The analogs are produced by eucaryotic cells transformed with a DNA construct comprising a strong transcriptional promoter directing the expression of a gene which encodes a protein having substantially the same biological activity as PDGF. Suitable genes include the v-sis gene or a derivative of the v-sis gene of simian sarcoma virus or portions thereof, or the human cDNA gene for PDGF or portions thereof. In particular, DNA sequences encoding polypeptides substantially homologous to the B chain of PDGF are preferred. A secretory signal sequence may be provided upstream of the gene, enabling secretion of the gene product from the host cell. Mitogenic activity is one of the biological activities possessed by these PDGF analogs, making them useful in promoting the growth of mammalian cells.

17. 发明公开

EP0118703A3 The use of glucose oxime to increase glucose isomerase activity in bacterial cells 失效
标题翻译：葡萄糖氧化酶在细菌细胞中增加葡萄糖异构体活性的应用
公开(公告)号：EP0118703A3
公开(公告)日：1986-05-21
申请号：EP84100854
申请日：1984-01-27
申请人： MILES LABORATORIES, INC.
发明人： Whitted, Beth E. , Boguslawski, George
IPC分类号： C12N09/92 , C12N09/38 , C12N01/38
CPC分类号： C12N1/38 , C12N9/2471 , C12N9/92 , C12Y302/01023 , C12Y503/01005 , Y10S435/849 , Y10S435/85
摘要： Disclosed is a method of increasing the production of enzymes involved in the production of carbohydrate metabolism by bacterium of the species F. arborescens or E. coli. The method involves growing the bacterium on an aqueous nutrient medium containing glucose oxime.

18. 发明公开

EP0077646A3 Method of culturing microbes belonging to the genus Bordetella and culture medium 有权
标题翻译：培养基因组和培养基的微生物培养方法
公开(公告)号：EP0077646A3
公开(公告)日：1986-03-26
申请号：EP82305465
申请日：1982-10-14
申请人： TEIJIN LIMITED
发明人： Suzuki, Yoji , Imaizumi, Atsushi , Yamaguchi, Hisao , Kanesaki, Masaharu , Ono, Shoji
IPC分类号： C12N01/20 , C12N01/38 , A61K39/10 , A61K35/74
CPC分类号： C12Q1/02 , C12N1/20 , C12N1/38 , Y10S435/822
摘要： A method of culturing microbes which belong to the genus Bordetella characterized by adding cyclodextrin or its derivative to the culture medium used for cultivating microbes belonging to the genus Bordetella and a culture medium therefor.

19. 发明公开

EP0059113A3 Improved bacterial growth medium and method of use 失效
标题翻译：改进的细菌生长培养基和使用方法
公开(公告)号：EP0059113A3
公开(公告)日：1983-05-18
申请号：EP82300964
申请日：1982-02-25
申请人： STATE OF OREGON, by and through the Oregon State Board of Higher Education on behalf of Oregon State University
发明人： Sandine, William E. , Ayres, James W.
IPC分类号： C12N01/20 , C12N01/00 , C12N01/38
CPC分类号： C12N1/38 , C12N1/00 , C12N1/20
摘要： An improved powdered bacterial growth medium com- positon adapted to be admixed with water is described. The powdered growth medium includes an alkali metal cation in a compound A admixed with a compound B containing an anion which reacts with the alkali metal cation in compound A in an aqueous growth medium to form an essentially water insoluble salt or base, including the alkali metal cation and the anion, which is acid neutralizing. The water insoluble salt is thus formed in situ in the aqueous growth medium when compounds A and B are added to the aqueous solution. Also described is an improved method for growing acid producing bacteria in an aqueous growth medium by forming the insoluble salt or base. The resulting growth medium is particularly adapted for neutralizing acids generated during growth of lactic acid producing bacteria which are grown for use in various food fermentations.

20. 发明公开

EP0207475A3 Process for secretive fermentation of lipids by fungi or algae 失效
标题翻译：真菌或ALGAE分泌脂肪的方法
公开(公告)号：EP0207475A3
公开(公告)日：1988-10-05
申请号：EP86108818
申请日：1986-06-28
申请人： KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA
发明人： Fukuda, Hideki
IPC分类号： C12P07/64 , C12N01/38
CPC分类号： C12P7/6463 , C12N1/38
摘要： In a process for preparing lipids by employing fungi or algae capable of biosynthesizing lipids, the improvement which comprises conducting the reaction in a reaction system wherein surfactants is present. According to the process of the present invention, the lipids can be obtained in much higher yield than the conventional process wherein surfac- tents is not present. Further, the process of the present invention can simplify the purification process and produce the lipids in high purity and in high yield, which is advantageously suitable for producing lipids in an industrial process.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式