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11. 发明公开

EP1814977A4 ARTHROSPIRA-BASED COMPOSITIONS AND USES THEREOF 有权
标题翻译：组合物及其用途节旋BASE
公开(公告)号：EP1814977A4
公开(公告)日：2009-11-11
申请号：EP05799363
申请日：2005-11-03
申请人： BIOVITE AUSTRALIA PTY LTD
发明人： DUNCAN KELVIN WINSTON , JOHNSTON PETER OWEN , BROWN ASHLEY MICHAEL
IPC分类号： C12N1/00 , A01N63/00 , A61K38/43 , A61P17/00 , C12N9/36
CPC分类号： A01N63/00 , A61K31/137 , A61K31/27 , A61K31/415 , A61K31/4164 , A61K31/4174 , A61K31/496 , A61K35/748 , C12N1/005 , C12N1/066 , C12N1/12 , C12N9/2434 , C12N9/2442 , C12N9/80 , C12Y302/01014 , C12Y302/01132 , C12Y305/01041 , A61K2300/00

12. 发明授权

US12129500B2 Methods for producing a polyactive carbohydrate and applications thereof 有权
公开(公告)号：US12129500B2
公开(公告)日：2024-10-29
申请号：US17245416
申请日：2021-04-30
申请人： BIOCAPITAL HOLDINGS, LLC
发明人： Raul Cuero Rengifo , Juliana Londono Murillo
IPC分类号： C12P19/14 , C12N9/10 , C12N9/16 , C12N9/24 , C12N9/42 , C12N9/80 , C12N15/52
CPC分类号： C12P19/14 , C12N9/1051 , C12N9/16 , C12N9/2434 , C12N9/80 , C12N15/52 , C12Y204/01016 , C12Y302/01132 , C12Y305/01041
摘要： Described herein are biological devices and methods for using the same to produce a polyactive carbohydrate. The biological devices include microbial cells transformed with a DNA construct containing genes for producing a chitin synthase, a chitosanase, and a chitin deacetylase. In some instances, the biological devices also include a gene for lipase. Methods for using the polyactive carbohydrate are also provided herein, including, but not limited to, enhancing the physiological properties of plants; medical applications; applications in the construction, materials science, and home goods industries; personal care, grooming, cosmetics, and oral care compositions containing the polyactive carbohydrate; methods for water decontamination; and the production of polyurethanes.

13. 发明申请

US20090123429A1 ARTHROSPIRA-BASED COMPOSITIONS AND USES THEREOF 有权
标题翻译：基于ARTHROSPIRA的组合物及其用途
公开(公告)号：US20090123429A1
公开(公告)日：2009-05-14
申请号：US11718247
申请日：2005-11-03
申请人： Kelvin Winston Duncan , Peter Owen Johnston , Ashley Michael Brown
发明人： Kelvin Winston Duncan , Peter Owen Johnston , Ashley Michael Brown
IPC分类号： A61K35/74 , A61P31/04 , A61P31/10
CPC分类号： A01N63/00 , A61K31/137 , A61K31/27 , A61K31/415 , A61K31/4164 , A61K31/4174 , A61K31/496 , A61K35/748 , C12N1/005 , C12N1/066 , C12N1/12 , C12N9/2434 , C12N9/2442 , C12N9/80 , C12Y302/01014 , C12Y302/01132 , C12Y305/01041 , A61K2300/00
摘要： The present invention concerns a composition comprising physiologically stressed Arthrospira maxima for use as a biocide and/or therapeutic. The invention also concerns a method for preventing or treating an infection or infestation of a subject by an organism, wherein the method comprises the step of administering to the subject an effective amount of a composition comprising physiologically stressed Arthrospira.
摘要翻译：本发明涉及一种包含用于杀生物剂和/或治疗剂的生理应激性关节炎最大值的组合物。本发明还涉及用于预防或治疗受体由生物体感染或感染的方法，其中所述方法包括向受试者施用有效量的包含生理应激节肢动物的组合物的步骤。

14. 发明申请

US20040229341A1 Method for the production of chitin deacetylase 审中-公开
标题翻译：生产甲壳素脱乙酰酶的方法
公开(公告)号：US20040229341A1
公开(公告)日：2004-11-18
申请号：US10777460
申请日：2004-02-12
发明人： Marie-France Versali , Clerisse Fabienne , Carole Gauthier , Francoise Dumont , Jacques Dommes
IPC分类号： C12N001/16 , C12N009/18 , C08B037/08 , C07H021/04 , C12N015/74
CPC分类号： C12N1/16 , C07K2319/21 , C12N9/80 , C12Y305/01041
摘要： In a first aspect, the present invention relates to a recombinant fungal strain, capable of expressing chitin deacetylase, which includes an expression vector that contains a nucleic acid molecule encoding chitin deacetylase, a suitable promoter and a transcription terminator. In particular, the present invention provides a recombinant Aspergillus oryzae strain capable of expressing chitin deacetylase obtained from Mucor rouxii. The present invention also relates to a method for producing chitin deacetylase by a recombinant fungal strain. In a second aspect, the present invention relates to a recombinant yeast strain, capable of expressing chitin deacetylase, which includes an expression vector that contains a nucleic acid molecule encoding chitin deacetylase, a suitable promoter and a transcription terminator. In particular, the present invention provides a recombinant Pichia pastoris strain capable of expressing chitin deacetylase obtained from Mucor rouxii. The present invention also relates to a method for producing chitin deacetylase by a recombinant yeast strain. The present invention further relates to purified recombinant chitin deacetylase enzyme.
摘要翻译：在第一方面，本发明涉及能够表达几丁质脱乙酰酶的重组真菌菌株，其包括含有编码壳多糖脱乙酰酶的核酸分子，合适的启动子和转录终止子的表达载体。特别地，本发明提供了能够表达从毛霉（Mucor rouxii）获得的几丁质脱乙酰酶的重组米曲霉菌株。本发明还涉及通过重组真菌菌株生产壳多糖脱乙酰酶的方法。在第二方面，本发明涉及能够表达几丁质脱乙酰酶的重组酵母菌株，其包含含有编码甲壳素脱乙酰酶的核酸分子，合适的启动子和转录终止子的表达载体。特别地，本发明提供能够表达从毛霉（Mucor rouxii）获得的几丁质脱乙酰酶的重组毕赤酵母菌株。本发明还涉及通过重组酵母菌株生产壳多糖脱乙酰酶的方法。本发明还涉及纯化的重组壳多糖脱乙酰酶。

15. 发明公开

US20240102036A1 POLYACTIVE CARBOHYDRATES AND METHODS OF USE THEREOF 审中-公开
公开(公告)号：US20240102036A1
公开(公告)日：2024-03-28
申请号：US17754506
申请日：2020-10-06
申请人： Bio Capital Holdings, LLC
发明人： Raul CUERO RENGIFO
IPC分类号： C12N15/82 , C12N9/10 , C12N9/24 , C12N9/80 , C12N15/81
CPC分类号： C12N15/8261 , C12N9/1051 , C12N9/2402 , C12N9/80 , C12N15/81 , C12Y204/01016 , C12Y204/01034 , C12Y302/01132 , C12Y305/01041
摘要： Described herein are biological devices and methods for using the same to produce a polyactive carbohydrate. The biological devices include microbial cells transformed with a DNA construct containing genes for producing a chitin synthase, a chitosanase, 5 and a chitin deacetylase, and, optionally, lipase, regulatory sequence CHR1, transglycosylase, dehydrogenase, and/or (1→3), (1→4)-β-glucan synthase. Methods for using the polyactive carbohydrate are also provided herein including, but not limited to, increasing plant hormone production and improving the appearance and root strength of plants and production of polyurethane biofoams.

16. 发明授权

US08808706B2 Arthrospira-based compositions and uses thereof 有权
标题翻译：基于节肢旋转的组合物及其用途
公开(公告)号：US08808706B2
公开(公告)日：2014-08-19
申请号：US11718247
申请日：2005-11-03
申请人： Kelvin Winston Duncan , Peter Owen Johnston , Ashley Michael Brown
发明人： Kelvin Winston Duncan , Peter Owen Johnston , Ashley Michael Brown
IPC分类号： A01N65/00
CPC分类号： A01N63/00 , A61K31/137 , A61K31/27 , A61K31/415 , A61K31/4164 , A61K31/4174 , A61K31/496 , A61K35/748 , C12N1/005 , C12N1/066 , C12N1/12 , C12N9/2434 , C12N9/2442 , C12N9/80 , C12Y302/01014 , C12Y302/01132 , C12Y305/01041 , A61K2300/00
摘要： The present invention concerns a composition comprising physiologically stressed Arthrospira maxima for use as a biocide and/or therapeutic. The invention also concerns a method for preventing or treating an infection or infestation of a subject by an organism, wherein the method comprises the step of administering to the subject an effective amount of a composition comprising physiologically stressed Arthrospira.
摘要翻译：本发明涉及一种包含用于杀生物剂和/或治疗剂的生理应激性关节炎最大值的组合物。本发明还涉及用于预防或治疗受体由生物体感染或感染的方法，其中所述方法包括向受试者施用有效量的包含生理应激节肢动物的组合物的步骤。

17. 发明申请

US20050042735A1 Metabolic engineering for enhanced production of chitin and chitosan in microorganisms 审中-公开
标题翻译：用于增强微生物中几丁质和壳聚糖生产的代谢工程
公开(公告)号：US20050042735A1
公开(公告)日：2005-02-24
申请号：US10823397
申请日：2004-04-12
申请人： Ming-De Deng , Thomas McMullin , Alan Grund
发明人： Ming-De Deng , Thomas McMullin , Alan Grund
IPC分类号： C07H21/04 , C12N1/18 , C12N1/20 , C12N9/00 , C12N9/10 , C12N9/24 , C12N9/80 , C12N9/88 , C12N15/00 , C12N15/52 , C12P20060101 , C12P19/04 , C12P19/26 , C12P19/28 , C12P21/06
CPC分类号： C12N15/52 , C12N9/1029 , C12N9/1051 , C12N9/1096 , C12N9/2442 , C12N9/80 , C12N9/88 , C12P19/26 , C12Y203/01004 , C12Y204/01016 , C12Y206/01016 , C12Y302/01014 , C12Y305/01041
摘要： Disclosed is a fermentation method for the production of commercially useful amounts of chitin and/or chitosan by a biosynthetic process. Also disclosed are genetically modified microorganisms useful in such a method and a microbial biomass containing chitin and/or chitosan produced by such a method.
摘要翻译：公开了通过生物合成方法生产商用有用量的几丁质和/或壳聚糖的发酵方法。还公开了可用于这种方法的遗传修饰微生物和含有通过这种方法生产的壳多糖和/或壳聚糖的微生物生物质。

18. 发明申请

WO2004092391A3 METABOLIC ENGINEERING FOR ENHANCED PRODUCTION OF CHITIN AND CHITOSAN IN MICROORGANISMS 审中-公开
标题翻译：代谢工程用于增强微生物中酪氨酸和酪氨酸的生产
公开(公告)号：WO2004092391A3
公开(公告)日：2005-11-24
申请号：PCT/US2004011286
申请日：2004-04-12
申请人： ARKION LIFE SCIENCES LLC
发明人： DENG MING-DE , MCMULLIN THOMAS W , GRUND ALAN D
IPC分类号： C07H21/04 , C12N1/18 , C12N1/20 , C12N9/00 , C12N9/10 , C12N9/24 , C12N9/80 , C12N9/88 , C12N15/00 , C12N15/52 , C12P20060101 , C12P19/04 , C12P19/26 , C12P19/28 , C12P21/06
CPC分类号： C12N15/52 , C12N9/1029 , C12N9/1051 , C12N9/1096 , C12N9/2442 , C12N9/80 , C12N9/88 , C12P19/26 , C12Y203/01004 , C12Y204/01016 , C12Y206/01016 , C12Y302/01014 , C12Y305/01041
摘要： Disclosed is a fermentation method for the production of commercially useful amounts of chitin and/or chitosan by a biosynthetic process. Also disclosed are genetically modified microorganisms useful in such a method and a microbial biomass containing chitin and/or chitosan produced by such a method.
摘要翻译：公开了通过生物合成方法生产商用有用量的壳多糖和/或壳聚糖的发酵方法。还公开了可用于这种方法的经遗传修饰的微生物和含有通过这种方法生产的壳多糖和/或壳聚糖的微生物生物质。

19. 发明申请

WO2004072280A1 METHOD FOR THE PRODUCTION OF CHITIN DEACETYLASE 审中-公开
标题翻译：生产脱乙酰壳多糖的方法
公开(公告)号：WO2004072280A1
公开(公告)日：2004-08-26
申请号：PCT/EP2004/001313
申请日：2004-02-12
申请人： KITOZYME S.A. , UNIVERSITE DE LIEGE , VERSALI, Marie-France , CLERISSE, Fabienne , GAUTHIER, Carole , DUMONT, Françoise , DOMMES, Jacques
发明人： VERSALI, Marie-France , CLERISSE, Fabienne , GAUTHIER, Carole , DUMONT, Françoise , DOMMES, Jacques
IPC分类号： C12N9/80
CPC分类号： C12N1/16 , C07K2319/21 , C12N9/80 , C12Y305/01041
摘要： In a first aspect, the present invention relates to a recombinant fungal strain, capable of expressing chitin deacetylase, comprising an expression vector that contains a nucleic acid molecule encoding chitin deacetylase, a suitable promoter and a transcription terminator. In particular, the present invention provides a recombinant Aspergillus oryzae strain capable of expressing chitin deacetylase obtained from Mucor rouxii. The present invention also relates to a method for producing chitin deacetylase by a recombinant fungal strain. In a second aspect, the present invention relates to a recombinant yeast strain, capable of expressing chitin deacetylase, comprising an expression vector that contains a nucleic acid molecule encoding chitin deacetylase, a suitable promoter and a transcription terminator. In particular, the present invention provides a recombinant Pichia pastoris strain capable of expressing chitin deacetylase obtained from Mucor rouxii. The present invention also relates to a method for producing chitin deacetylase by a recombinant yeast strain. The present invention further relates to purified recombinant chitin deacetylase enzyme.
摘要翻译：在第一方面，本发明涉及能够表达几丁质脱乙酰酶的重组真菌菌株，其包含含有编码甲壳素脱乙酰酶的核酸分子，合适的启动子和转录终止子的表达载体。特别地，本发明提供了能够表达从毛霉（Mucor rouxii）获得的几丁质脱乙酰酶的重组米曲霉菌株。本发明还涉及通过重组真菌菌株生产壳多糖脱乙酰酶的方法。在第二方面，本发明涉及能够表达几丁质脱乙酰酶的重组酵母菌株，其包含含有编码甲壳素脱乙酰酶的核酸分子，合适的启动子和转录终止子的表达载体。特别地，本发明提供能够表达从毛霉（Mucor rouxii）获得的几丁质脱乙酰酶的重组毕赤酵母菌株。本发明还涉及通过重组酵母菌株生产壳多糖脱乙酰酶的方法。本发明还涉及纯化的重组壳多糖脱乙酰酶。

20. 发明授权

EP1814977B1 ARTHROSPIRA-BASED COMPOSITIONS AND USES THEREOF 有权
标题翻译：组合物及其用途节旋BASE
公开(公告)号：EP1814977B1
公开(公告)日：2014-06-18
申请号：EP05799363.6
申请日：2005-11-03
申请人： Biovite Australia Pty Ltd
发明人： DUNCAN, Kelvin Winston , JOHNSTON, Peter Owen , BROWN, Ashley Michael
IPC分类号： C12N1/12 , A01N63/00 , A61K38/43 , A61P17/00 , C12N9/36
CPC分类号： A01N63/00 , A61K31/137 , A61K31/27 , A61K31/415 , A61K31/4164 , A61K31/4174 , A61K31/496 , A61K35/748 , C12N1/005 , C12N1/066 , C12N1/12 , C12N9/2434 , C12N9/2442 , C12N9/80 , C12Y302/01014 , C12Y302/01132 , C12Y305/01041 , A61K2300/00

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