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11. 发明公开

CN106492202A 新活性蛋白酶药酒无效
公开(公告)号：CN106492202A
公开(公告)日：2017-03-15
申请号：CN201611106130.9
申请日：2016-12-06
申请人：葛龙海
发明人：葛龙海
IPC分类号： A61K38/48 , A61P29/00 , A61P19/00 , A61P19/02 , A61K35/50
CPC分类号： A61K35/50 , A61K9/0095 , A61K38/4806 , C12Y304/00 , A61K2300/00
摘要：本发明提供了新活性蛋白酶药酒，是由下列重量份的原料制成：胎盘组织液50～70份、活蝎蛋白酶20～40份、白酒10～30份，所述白酒为45～56度。本发明各种中药配伍合理、科学，经大量临床验证，无毒无副作用，具有疗程短、疗效快速、治疗彻底、不复发的优点，具有明显的镇痛、解毒、除湿、活血通络等作用。

12. 发明公开

CN106492201A 一种用于压疮的药膏及其制备方法无效
公开(公告)号：CN106492201A
公开(公告)日：2017-03-15
申请号：CN201611093807.X
申请日：2016-12-02
申请人：郑州莉迪亚医药科技有限公司
发明人：不公告发明人
IPC分类号： A61K38/48 , A61K9/06 , A61P17/02 , A61K31/047 , A61K31/133 , A61K31/185 , A61K31/192 , A61K31/366 , A61K31/5383 , A61K31/573 , A61K31/7056 , A61K31/7068 , A61K31/722
CPC分类号： A61K31/133 , A61K9/0014 , A61K9/06 , A61K31/047 , A61K31/185 , A61K31/192 , A61K31/366 , A61K31/5383 , A61K31/573 , A61K31/7056 , A61K31/7068 , A61K31/722 , A61K38/4806 , A61K2300/00
摘要：本发明公开了一种用于压疮的药膏，由以下原料按照重量份组成：三乙醇胺7-12份、地塞米松0.5-5份、复合维生素0.1-1.5份、蚯蚓蛋白酶0.2-1份、泼尼松4-11份、氧氟沙星6-11份、甘油3-7份、免疫蛋白粉0.5-3份、利巴韦林4-6份、卡培他滨1-5份、壳聚糖5-8份、青蒿素0.1-0.8份、布络芬片4-10份和牛磺酸1-4份。本发明还公布了该药膏的制备方法。本发明原料来源广泛，制备工艺简单，适用于大规模的工业化生产；本发明中各组分起协同作用，配方合理，使用方便，治疗时间短，抗菌消炎止痛效果好，促进肉芽组织和上皮组织的形成，皮肤组织愈合和修复快，不易复发并且没有毒副作用。

13. 发明申请

US20150093369A1 MIXTURE OF ENZYMES FROM ANTARCTIC KRILL FOR USE IN THE REMOVAL OF A BIOFILM 审中-公开
标题翻译：用于去除生物薄膜的来自牛皮癣菌的混合物
公开(公告)号：US20150093369A1
公开(公告)日：2015-04-02
申请号：US14390598
申请日：2013-03-15
申请人： ARCIMBOLDO AB
发明人： Max Rutman , Wolfgang Vanscheidt , Jan Vincent , Frank Kochinke
IPC分类号： A61K38/46 , A61K35/56
CPC分类号： A61K38/46 , A61K35/612 , A61K38/4806
摘要： The invention concerns a mixture of enzymes from krill for use in the treatment of a soft tissue including epithelial tissue and mucosa on which soft tissue a biofilm has formed or is expected to form, which soft tissue is a soft tissue of a mammal and which treatment comprises the removal of the biofilm or preventing a formation of the biofilm.
摘要翻译：本发明涉及来自磷虾的酶的混合物，用于治疗包括上皮组织和粘膜的软组织，其上形成或预期形成生物膜的软组织，哪种软组织是哺乳动物的软组织，哪种处理包括去除生物膜或防止生物膜的形成。

14. 发明授权

US09308243B2 Cellular enhancements in biological systems through the use of li-pofullerene and peptide group combinations 有权
标题翻译：通过使用富勒烯和肽组合组合来生物系统中的细胞增强
公开(公告)号：US09308243B2
公开(公告)日：2016-04-12
申请号：US14656304
申请日：2015-03-12
申请人： LivePet, LLC
发明人： Ian Mitchell , Ayyappan Subbiah , Daniel David Bensimon
IPC分类号： A61K38/48 , A61K38/07 , A61K31/015
CPC分类号： A61K38/4806 , A61K31/00 , A61K31/015 , A61K35/618 , A61K36/63 , A61K38/05 , A61K38/07 , A61K38/4886 , C12Y304/2404 , A61K2300/00
摘要： In some embodiments, a chemical composition may include C60, serrapeptase, or a tetrapeptide. The tetrapeptide may include ALA,GLU,ASP,GLY. In some embodiments, the chemical composition may include a dipeptide. The dipeptide may include carnosine or camatine. In some embodiments, the chemical composition may include at least one lipid. One or more components of the chemical composition may be suspended in and/or dissolved in the at least one lipid. At least one lipid may include olive oil or mussel oil. In some embodiments, a method may include administering to a subject an effective amount of a pharmaceutically acceptable formulation comprising the chemical composition. The method may include inhibiting and/or ameliorating inflammation and/or a malady associated with inflammation. In some embodiments, the subject may include a human or a nonhuman mammal. Nonhuman mammals may include equines, canines, or felines.
摘要翻译：在一些实施方案中，化学组合物可包括C60，锯齿酶解酶或四肽。四肽可以包括ALA，GLU，ASP，GLY。在一些实施方案中，化学组合物可以包括二肽。二肽可以包括肌肽或卡马汀。在一些实施方案中，化学组合物可以包括至少一种脂质。化学组合物的一种或多种组分可以悬浮在和/或溶解于至少一种脂质中。至少一种脂质可以包括橄榄油或贻贝油。在一些实施方案中，方法可以包括向受试者施用有效量的包含化学组成的药学上可接受的制剂。该方法可以包括抑制和/或改善炎症和/或与炎症相关的疾病。在一些实施方案中，受试者可以包括人或非人类哺乳动物。非人类哺乳动物可能包括马，犬或猫科动物。

15. 发明申请

US20150328290A1 COSMETIC COMPOSITIONS FROM FISH HATCHING FLUID 审中-公开
标题翻译：来自FISH HATCHING FLUID的化妆品组合物
公开(公告)号：US20150328290A1
公开(公告)日：2015-11-19
申请号：US14654146
申请日：2012-12-21
申请人： AQUA BIO TECHNOLOGY ASA
发明人： Hans Kristian LEREN , Fanny FAGOT
IPC分类号： A61K38/48 , A61K38/17 , A61Q19/10 , A61K8/64 , A61Q19/00 , A61K35/60 , A61K8/66
CPC分类号： A61K38/482 , A61K8/64 , A61K8/66 , A61K8/987 , A61K35/60 , A61K38/1706 , A61K38/4806 , A61K2800/28 , A61Q19/00 , A61Q19/007 , A61Q19/10
摘要： The present invention relates to pharmaceutical or cosmetic compositions obtained or obtainable from fish hatching fluid comprising polypeptides or portions thereof and the use of said compositions in various medical and cosmetic applications to the skin, particularly for moisturizing skin and/or for exfoliation of the horny layer of the skin for treating or preventing skin disorders or conditions in an animal.
摘要翻译：本发明涉及由包含多肽或其部分的鱼孵化液获得或可获得的药物或化妆品组合物，以及在各种医疗和化妆品应用中对皮肤的用途，特别是用于保湿皮肤和/或角质层的剥离的皮肤，用于治疗或预防动物的皮肤病症或病症。

16. 发明申请

US20140328818A1 Proteases for Degrading Gluten 有权
标题翻译：蛋白酶降解麸质
公开(公告)号：US20140328818A1
公开(公告)日：2014-11-06
申请号：US14008478
申请日：2012-03-30
申请人： Pawan Kumar
发明人： Pawan Kumar
IPC分类号： C12N9/64 , A23L1/03 , A61K38/48
CPC分类号： C12N9/6405 , A23L29/06 , A23V2002/00 , A61K38/48 , A61K38/4806 , A61K38/4813 , A61K38/4873 , A61K2300/00
摘要： Gluten-degrading proteases derived from insects, including flour beetles, are isolated, and the purified, and recombinant forms can be used to make gluten-containing food safe for patients suffering from gluten intolerance.
摘要翻译：分离出来自昆虫（包括面粉甲虫）的麸质降解蛋白酶，纯化的和重组形式可用于使麸质食物对于面筋不耐受的患者安全。

17. 发明公开

EP2341925A4 COMPOSITION OF THROMBOLYTIC AGENT AND ANTI THROMBOSIS AND ALSO ITS PRODUCTION METHOD 有权
标题翻译：血栓溶解剂的组成的血栓形成抑制剂及其制备方法
公开(公告)号：EP2341925A4
公开(公告)日：2012-06-27
申请号：EP09812761
申请日：2009-08-20
申请人： PT DEXA MEDICA
发明人： TJANDRAWINATA RAYMOND R , TRISINA JESSICA
IPC分类号： A61K35/64 , A61K38/48 , A61P7/02
CPC分类号： A61K35/56 , A61K38/4806
摘要： The present invention discloses a composition comprising a thrombolytic agent derived from an earthworm extract for treating and/or preventing diseases related to vascular blockage due to thrombosis. The composition may include suitable pharmaceutical excipients for preparation of pharmaceutical compositions including tablets, powders, capsules, granules, pellets and caplets. The invention also discloses the process for producing the earthworm extract, which includesr preparation of the earthworms by washing with aqueous alcohol, freezing, extracting, separation using filtration and/or centrifugation, concentrating the liquid extract followed by solidification and drying of the final extract.

18. 发明公开

EP2341925A1 COMPOSITION OF THROMBOLYTIC AGENT AND ANTI THROMBOSIS AND ALSO ITS PRODUCTION METHOD 有权
标题翻译：溶栓剂/血栓抑制剂及其制备方法
公开(公告)号：EP2341925A1
公开(公告)日：2011-07-13
申请号：EP09812761.6
申请日：2009-08-20
申请人： Pt. Dexa Medica
发明人： TJANDRAWINATA, Raymond, R. , TRISINA, Jessica
IPC分类号： A61K38/57 , A61P7/02
CPC分类号： A61K35/56 , A61K38/4806
摘要： The present invention discloses a composition comprising a thrombolytic agent derived from an earthworm extract for treating and/or preventing diseases related to vascular blockage due to thrombosis. The composition may include suitable pharmaceutical excipients for preparation of pharmaceutical compositions including tablets, powders, capsules, granules, pellets and caplets. The invention also discloses the process for producing the earthworm extract, which includesr preparation of the earthworms by washing with aqueous alcohol, freezing, extracting, separation using filtration and/or centrifugation, concentrating the liquid extract followed by solidification and drying of the final extract.

19. 发明公开

EP3209323A4 IMPROVED CLOTTING COMPOSITION 审中-公开
公开(公告)号：EP3209323A4
公开(公告)日：2018-07-25
申请号：EP15852949
申请日：2015-10-23
申请人： Q SERA PTY LTD
发明人： MASCI PAUL , ZHAO KONG-NAN , LAVIN MARTIN , DE JERSEY JOHN , DIMESKI GOCE
IPC分类号： A61K38/36 , A61K38/00 , A61K38/17 , A61K38/38 , A61K38/48 , A61P7/00 , C12N9/64 , C12Q1/56 , G01N33/49 , G01N33/86
CPC分类号： A61K38/36 , A61K38/00 , A61K38/1703 , A61K38/38 , A61K38/4806 , C12N9/6418 , C12Q1/56 , C12Y304/21006 , G01N33/00 , G01N33/86 , A61K2300/00
摘要： The present invention relates to improved clotting compositions for producing high quality blood serum samples for analyte testing, such as for pathology testing and other biological assays. In particular, the present invention relates to the use of prothrombin activators in combination with stabilizing agents such as colloids for producing high quality blood serum samples. The present invention also relates to associated methods for preparing clotting compositions, tubes, kits and methods of diagnosis, prognosis and monitoring for responsiveness to therapy.

20. 发明授权

US09267128B2 Proteases for degrading gluten 有权
标题翻译：降解麸质蛋白酶
公开(公告)号：US09267128B2
公开(公告)日：2016-02-23
申请号：US14008478
申请日：2012-03-30
申请人： Pawan Kumar
发明人： Pawan Kumar
IPC分类号： A61K38/54 , A61K38/43 , C12N9/64 , A61K38/48 , A23L1/03
CPC分类号： C12N9/6405 , A23L29/06 , A23V2002/00 , A61K38/48 , A61K38/4806 , A61K38/4813 , A61K38/4873 , A61K2300/00
摘要： Gluten-degrading proteases derived from insects, including flour beetles, are isolated, and the purified, and recombinant forms can be used to make gluten-containing food safe for patients suffering from gluten intolerance.
摘要翻译：分离出来自昆虫（包括面粉甲虫）的麸质降解蛋白酶，并且纯化的和重组形式可用于使麸质食物对于面筋不耐受的患者安全。

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