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11. 发明授权

US09020579B2 System and method for dual energy and/or contrast enhanced breast imaging for screening, diagnosis and biopsy 有权
标题翻译：用于筛选，诊断和活检的双能量和/或对比度增强乳腺成像的系统和方法
公开(公告)号：US09020579B2
公开(公告)日：2015-04-28
申请号：US13415675
申请日：2012-03-08
申请人： Andrew P. Smith , Jay A. Stein , Zhenxue Jing , Baorui Ren , Loren Niklason , Christopher Ruth , Ian Shaw
发明人： Andrew P. Smith , Jay A. Stein , Zhenxue Jing , Baorui Ren , Loren Niklason , Christopher Ruth , Ian Shaw
IPC分类号： A61B5/05 , A61B6/02 , A61B6/12 , A61B6/00
CPC分类号： A61B6/025 , A61B6/12 , A61B6/4035 , A61B6/4417 , A61B6/463 , A61B6/466 , A61B6/481 , A61B6/482 , A61B6/502 , A61B6/5235 , A61B10/04 , A61M5/007 , F04C2270/041
摘要： Systems and methods for x-ray imaging a patient's breast in combinations of dual-energy, single-energy, mammography and tomosynthesis modes that facilitate screening for and diagnosis of breast abnormalities, particularly breast abnormalities characterized by abnormal vascularity.
摘要翻译：双能量，单能量，乳房X射线摄影和断层合成模式的X射线成像的X射线成像系统和方法，有助于筛查和诊断乳房异常，特别是以血管异常为特征的乳房异常。

12. 发明授权

US08768026B2 X-ray imaging with x-ray markers that provide adjunct information but preserve image quality 有权
标题翻译： X射线成像与X射线标记提供辅助信息，但保留图像质量
公开(公告)号：US08768026B2
公开(公告)日：2014-07-01
申请号：US12150539
申请日：2008-04-28
申请人： Baorui Ren , Andrew P. Smith , Zhenxue Jing , Jay A. Stein , Kenneth F. DeFreitas
发明人： Baorui Ren , Andrew P. Smith , Zhenxue Jing , Jay A. Stein , Kenneth F. DeFreitas
IPC分类号： A61B6/03 , A61B6/00 , A61B6/04 , A61B5/107
CPC分类号： A61B6/502 , A61B5/1075 , A61B6/0414 , A61B6/544 , A61B6/583 , G06F19/00
摘要： A method and an apparatus for estimating a geometric thickness of a breast in mammography/tomosynthesis or in other x-ray procedures, by imaging markers that are in the path of x-rays passing through the imaged object. The markings can be selected to be visible or to be invisible when the composite markings/breast image is viewed in clinical settings. If desired, the contribution of the markers to the image can be removed through further processing. The resulting information can be used determining the geometric thickness of the body being x-rayed and thus setting imaging parameters that are thickness-related, and for other purposes. The method and apparatus also have application in other types of x-ray imaging.
摘要翻译：一种用于通过成像穿过成像对象的x射线路径中的标记来估计乳房X线照相术/断层合成或其他x射线程序中的乳房的几何厚度的方法和装置。当在临床设置中观看复合标记/乳房图像时，标记可以被选择为可见或不可见。如果需要，标记对图像的贡献可以通过进一步处理去除。可以使用所得到的信息来确定被X射线的身体的几何厚度，从而设置与厚度相关的成像参数，并且用于其他目的。该方法和装置也可用于其他类型的X射线成像。

13. 发明授权

US07245694B2 X-ray mammography/tomosynthesis of patient's breast 有权
公开(公告)号：US07245694B2
公开(公告)日：2007-07-17
申请号：US11203852
申请日：2005-08-15
申请人： Zhenxue Jing , Loren Niklason , Jay Stein , Ian Shaw , Ken Defreitas , Tom Farbizio , Christopher Ruth , Baorui Ren , Andrew Smith
发明人： Zhenxue Jing , Loren Niklason , Jay Stein , Ian Shaw , Ken Defreitas , Tom Farbizio , Christopher Ruth , Baorui Ren , Andrew Smith
IPC分类号： A61B6/04
CPC分类号： A61B6/4429 , A61B6/025 , A61B6/102 , A61B6/4028 , A61B6/4417 , A61B6/502 , A61B6/583
摘要： A breast x-ray system and method using tomosynthesis imaging in which the x-ray source generally moves away from the patient's head. The system may include an operation mode in which it additionally takes mammogram image data.

14. 发明授权

US08457282B2 Method and system for controlling X-ray focal spot characteristics for tomosynthesis and mammography imaging 有权
标题翻译：控制X射线焦点特征的方法和系统，用于体层摄影和乳房X线照相成像
公开(公告)号：US08457282B2
公开(公告)日：2013-06-04
申请号：US12623472
申请日：2009-11-23
申请人： Ren Baorui , Jay Stein , Zhenxue Jing , Andrew Smith
发明人： Ren Baorui , Jay Stein , Zhenxue Jing , Andrew Smith
IPC分类号： H01J35/30 , G01N23/083 , H05G1/60 , A61B6/04
CPC分类号： A61B6/4021 , A61B6/025 , A61B6/032 , A61B6/502 , H01J35/14 , H05G1/52
摘要： An x-ray tube is described that includes components for increasing x-ray image clarity in the presence of a moving x-ray source by modifying focal spot characteristics, including focal spot size and focal spot position. In a first arrangement a static focal spot is moved in a direction contrary to the movement of the x-ray source so that an effective focal spot position is essentially fixed in space relative to one of the imaged object and/or detector during a tomosynthesis exposure. In a second arrangement, the size of the static focal spot is increased, and the resulting increase in tube current reduces the exposure time and concomitant blur effect. The methods may be used alone or in combination; for example an x-ray tube with a larger, moveable static focal spot will result in a system that fully utilizes the x-ray tube generator, provides a high quality image with reduced blur and, due to the decrease in exposure time, may scan the patient more quickly.
摘要翻译：描述了一种X射线管，其包括用于通过改变焦点特性（包括焦点尺寸和焦斑位置）来增加在存在移动的X射线源的情况下增加x射线图像清晰度的部件。在第一布置中，静止焦点在与x射线源的移动相反的方向上移动，使得在断层合成曝光期间相对于成像对象和/或检测器中的一个，有效焦点位置基本上固定在空间中。在第二种布置中，静态焦点的尺寸增加，并且由此导致的管电流的增加降低了曝光时间并伴随着模糊效果。这些方法可以单独使用或组合使用; 例如具有较大的可移动静电焦斑的X射线管将导致完全利用x射线管发生器的系统，提供具有减少的模糊的高质量图像，并且由于曝光时间的减少可能扫描病人更快

15. 发明申请

US20110188624A1 TOMOSYNTHESIS WITH SHIFTING FOCAL SPOT AND OSCILLATING COLLIMATOR BLADES 有权
标题翻译：具有移位焦点位置和振荡收缩片的TOMOSYNTHESIS
公开(公告)号：US20110188624A1
公开(公告)日：2011-08-04
申请号：US12849294
申请日：2010-08-03
申请人： Baorui Ren , Andrew Smith , Tom Farbizio , Zhenxue Jing , Jay Stein
发明人： Baorui Ren , Andrew Smith , Tom Farbizio , Zhenxue Jing , Jay Stein
IPC分类号： A61B6/03 , G21K1/04
CPC分类号： A61B6/06 , A61B6/025 , A61B6/03 , A61B6/035 , A61B6/502 , G21K1/02 , G21K1/04
摘要： In a tomosynthesis system a static focal spot is moved in a direction opposite to and generally synchronized with the directional movement of an x-ray source and X-ray collimator blades are moved during each exposure in synchronization with the shifting of the static focal spot. The synchronized movement of the static focal spot, x-ray tube and collimator blades helps keep the effective focal spot fixed in space relative to the breast, detector or both during the entire duration of the exposure and keeps the x-ray field on the detector and breast static. The shifting collimator blades follow an oscillating pattern over the multiple x-ray exposures of a tomosynthesis scan.
摘要翻译：在断层合成系统中，静态焦点沿着与X射线源的定向运动相反并且大体上与X射线源的定向运动相同的方向移动，并且与静态焦点的移动同步地在每次曝光期间移动X射线准直器叶片。静态焦点，X射线管和准直器刀片的同步运动有助于在曝光的整个持续时间内将有效焦斑保持在相对于乳房，检测器或两者的空间中，并将X射线场保持在检测器和乳房静电。移位准直器刀片遵循断层扫描合成扫描的多次X射线曝光的振荡模式。

16. 发明授权

US07583786B2 X-ray mammography/tomosynthesis of patient's breast 有权
标题翻译： X线X线摄影/患者乳房断层合成
公开(公告)号：US07583786B2
公开(公告)日：2009-09-01
申请号：US11810539
申请日：2007-06-06
申请人： Zhenxue Jing , Loren Niklason , Jay Stein , Ian Shaw , Ken DeFreitas , Tom Farbizio , Christopher Ruth , Baorui Ren , Andrew Smith
发明人： Zhenxue Jing , Loren Niklason , Jay Stein , Ian Shaw , Ken DeFreitas , Tom Farbizio , Christopher Ruth , Baorui Ren , Andrew Smith
IPC分类号： A61B6/04
CPC分类号： A61B6/4429 , A61B6/025 , A61B6/102 , A61B6/4028 , A61B6/4417 , A61B6/502 , A61B6/583
摘要： A breast x-ray system and method using tomosynthesis imaging in which the x-ray source generally moves away from the patient's head. The system may include an operation mode in which it additionally takes mammogram image data.
摘要翻译：一种乳房x射线系统和使用断层摄影成像的方法，其中x射线源通常远离患者的头部移动。该系统可以包括另外采用乳房X线照片图像数据的操作模式。

17. 发明申请

US20070242800A1 X-ray mammography/tomosynthesis of patient's breast 有权
公开(公告)号：US20070242800A1
公开(公告)日：2007-10-18
申请号：US11810539
申请日：2007-06-06
申请人： Zhenxue Jing , Loren Niklason , Jay Stein , Ian Shaw , Ken DeFreitas , Tom Farbizio , Christopher Ruth , Baorui Ren , Andrew Smith
发明人： Zhenxue Jing , Loren Niklason , Jay Stein , Ian Shaw , Ken DeFreitas , Tom Farbizio , Christopher Ruth , Baorui Ren , Andrew Smith
IPC分类号： A61B6/04 , G06K9/00
CPC分类号： A61B6/4429 , A61B6/025 , A61B6/102 , A61B6/4028 , A61B6/4417 , A61B6/502 , A61B6/583
摘要： A breast x-ray system and method using tomosynthesis imaging in which the x-ray source generally moves away from the patient's head. The system may include an operation mode in which it additionally takes mammogram image data.

18. 发明申请

US20150157288A9 DETECTING AND QUANTIFYING PATIENT MOTION DURING TOMOSYNTHESIS SCANS 有权
标题翻译：在TOMOSYNTHESIS扫描期间检测和定量患者运动
公开(公告)号：US20150157288A9
公开(公告)日：2015-06-11
申请号：US13198352
申请日：2011-08-04
申请人： Baorui Ren , Loren Niklason , Andrew Smith , Zhenxue Jing , Jay Stein
发明人： Baorui Ren , Loren Niklason , Andrew Smith , Zhenxue Jing , Jay Stein
IPC分类号： G06K9/00 , A61B6/02 , A61B5/00 , A61B5/055 , A61B8/13 , A61B8/08 , A61B6/00 , A61B6/03
CPC分类号： A61B6/5264 , A61B5/055 , A61B5/7207 , A61B6/025 , A61B6/035 , A61B6/0414 , A61B6/461 , A61B6/481 , A61B6/502 , A61B6/5223 , A61B8/13 , A61B8/5276 , G06F19/00 , G06T7/246 , G06T2207/10112 , G06T2207/30068
摘要： The effects of patient motion in tomosynthesis scan images are automatically detected and quantified. In at least one embodiment an indication of detection of the effects of patient motion in tomosynthesis scan images is provided shortly after the scan, e.g., before the patient is discharged or before the breast is decompressed. A patient motion score may be calculated as part of motion quantification. The score may be stored for subsequent retrieval. Images may be presented with reference features to help a technician confirm of the effects of motion in images.
摘要翻译：自动检测和量化在体层摄影扫描图像中患者运动的影响。在至少一个实施例中，在扫描之后不久，例如在患者被排出之前或在乳房被减压之前，提供了在层析合成扫描图像中患者运动的影响的检测指示。患者运动评分可以作为运动量化的一部分计算。该分数可以存储用于随后的检索。图像可以呈现参考特征，以帮助技术人员确认图像中运动的影响。

19. 发明授权

US09498180B2 Detecting and quantifying patient motion during tomosynthesis scans 有权
标题翻译：在层析扫描期间检测和量化患者运动
公开(公告)号：US09498180B2
公开(公告)日：2016-11-22
申请号：US13198352
申请日：2011-08-04
申请人： Baorui Ren , Loren Niklason , Andrew Smith , Zhenxue Jing , Jay Stein
发明人： Baorui Ren , Loren Niklason , Andrew Smith , Zhenxue Jing , Jay Stein
IPC分类号： G06K9/00 , A61B6/00 , A61B6/02 , G06T7/20 , A61B5/055 , A61B5/00 , A61B6/03 , A61B8/13 , A61B8/08 , A61B6/04
CPC分类号： A61B6/5264 , A61B5/055 , A61B5/7207 , A61B6/025 , A61B6/035 , A61B6/0414 , A61B6/461 , A61B6/481 , A61B6/502 , A61B6/5223 , A61B8/13 , A61B8/5276 , G06F19/00 , G06T7/246 , G06T2207/10112 , G06T2207/30068
摘要： The effects of patient motion in tomosynthesis scan images are automatically detected and quantified. In at least one embodiment an indication of detection of the effects of patient motion in tomosynthesis scan images is provided shortly after the scan, e.g., before the patient is discharged or before the breast is decompressed. A patient motion score may be calculated as part of motion quantification. The score may be stored for subsequent retrieval. Images may be presented with reference features to help a technician confirm of the effects of motion in images.
摘要翻译：自动检测和量化在体层摄影扫描图像中患者运动的影响。在至少一个实施例中，在扫描之后不久，例如在患者被排出之前或在乳房被减压之前，提供了在层析合成扫描图像中患者运动的影响的检测指示。患者运动评分可以作为运动量化的一部分计算。该分数可以存储用于随后的检索。图像可以呈现参考特征，以帮助技术人员确认图像中运动的影响。

20. 发明授权

US08515005B2 Tomosynthesis with shifting focal spot and oscillating collimator blades 有权
标题翻译：具有移动焦点和振荡准直器叶片的合成
公开(公告)号：US08515005B2
公开(公告)日：2013-08-20
申请号：US12849294
申请日：2010-08-03
申请人： Baorui Ren , Andrew Smith , Tom Farbizio , Zhenxue Jing , Jay Stein
发明人： Baorui Ren , Andrew Smith , Tom Farbizio , Zhenxue Jing , Jay Stein
IPC分类号： A61B6/04 , A61B6/00 , G21K5/10
CPC分类号： A61B6/06 , A61B6/025 , A61B6/03 , A61B6/035 , A61B6/502 , G21K1/02 , G21K1/04
摘要： In a tomosynthesis system a static focal spot is moved in a direction opposite to and generally synchronized with the directional movement of an x-ray source and X-ray collimator blades are moved during each exposure in synchronization with the shifting of the static focal spot. The synchronized movement of the static focal spot, x-ray tube and collimator blades helps keep the effective focal spot fixed in space relative to the breast, detector or both during the entire duration of the exposure and keeps the x-ray field on the detector and breast static. The shifting collimator blades follow an oscillating pattern over the multiple x-ray exposures of a tomosynthesis scan.
摘要翻译：在断层合成系统中，静态焦点沿着与X射线源的定向运动相反并且大体上与X射线源的定向运动相同的方向移动，并且与静态焦点的移动同步地在每次曝光期间移动X射线准直器叶片。静态焦点，X射线管和准直器刀片的同步运动有助于在曝光的整个持续时间内将有效焦斑保持在相对于乳房，检测器或两者的空间中，并将X射线场保持在检测器和乳房静电。移位准直器刀片遵循断层扫描合成扫描的多次X射线曝光的振荡模式。

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