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11. 发明公开

EP3426259A1 PHOSPHOLIPID PREPARATIONS FOR THE IMPROVEMENT OF BRAIN PLASTICITY 审中-实审转让
公开(公告)号：EP3426259A1
公开(公告)日：2019-01-16
申请号：EP17762599.3
申请日：2017-03-09
申请人： Enzymotec Ltd.
发明人： WIDBERG, Asher , LAOZ, Hala , BEN-DROR, Gai , BERKOV, Yifat , LIFSHITZ, Yael , HERZOG, Yael
IPC分类号： A61K31/685 , C07F9/02 , A23D9/013

12. 发明授权

EP1898722B1 POLAR LIPID MIXTURES, THEIR PREPARATION AND USES 有权
标题翻译：极性脂质混合物，生产与使用
公开(公告)号：EP1898722B1
公开(公告)日：2013-04-10
申请号：EP06728307.7
申请日：2006-04-27
申请人： Enzymotec Ltd.
发明人： SHULMAN, Avidor , ZUABI, Rassan , BEN DROR, Gai , TWITO, Yoni , PELLED, Dori , HERZOG, Yael
IPC分类号： A23L1/29 , A23J7/00 , A61P25/28 , C07F9/10 , A23L1/30
CPC分类号： A23J7/00 , A23L33/115 , A23V2002/00 , A23V2250/185 , A23V2250/1852 , A23V2250/1848
摘要： Disclosed herein are polar lipid mixtures, comprising glycerophospholipids such as phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylserine (PS) and phosphatidylinositol (PI), and sphingolipids such as sphyngomyelin (SM). Most importantly, the ratio of phospholipids in said mixture is comparable to that of HMF, and is represented by SM>PC>PE>PS>PI or SM=PC>PE>PS>PI. Processes for the preparation of said mixtures and uses thereof are also described herein.

13. 发明公开

EP3258789A1 OIL BLENDS, PROCESSES FOR THE PREPARATION THEREOF AND THEIR USE IN FORMULAS 有权转让
标题翻译：油混合物，其制备方法及其在配方中的用途
公开(公告)号：EP3258789A1
公开(公告)日：2017-12-27
申请号：EP16718024.9
申请日：2016-02-16
申请人： Enzymotec Ltd.
发明人： WIDBERG, Asher , NUMA, Ran , BAR-YOSEPH, Fabiana , ZUABI, Rassan , HERZOG, Yael , BEN-DROR, Gai
IPC分类号： A23D9/00 , A23D9/007 , A23D9/06 , C11B5/00
CPC分类号： A23D9/007 , A23D9/04 , A23L33/11 , A23L33/40 , A61K36/28 , A61K36/286 , A61K36/31 , A61K36/48 , A61K36/889 , C11B3/12 , A61K2300/00
摘要： The invention provides oil blends, processes for the preparation thereof and their uses.

14. 发明公开

EP3076978A1 SERINE GLYCEROPHOSPHOLIPID PREPARATION AND METHOD FOR TREATMENT OF SEIZURES 无效
标题翻译：制造SERINGLYCEROPHOSPHOLIPID和法治疗癫痫
公开(公告)号：EP3076978A1
公开(公告)日：2016-10-12
申请号：EP14867329.6
申请日：2014-12-05
申请人： Enzymotec Ltd.
发明人： ZAAROOR REGEV, Daphna , HERZOG, Yael , CHUDNOW, Robert , RICHTER, Yael , SORIA ARTZI, Gali, Olga
IPC分类号： A61K31/66 , A61K47/48 , A61P25/08
CPC分类号： A61K31/202 , A61K31/19 , A61K31/216 , A61K31/423 , A61K31/513 , A61K31/55 , A61K31/5513 , A61K31/685 , A61K45/06 , A61K47/24 , A61K47/542 , A61K47/544 , A61K2300/00
摘要： A preparation for treatment and/or prevention of seizures comprising a non-mammalian derived mixture of serine glycerophospholipids (PS) conjugates, wherein the mixture comprises (a) Eicosapentaenoic acid (EPA) conjugated to PS and (b) Docosahexaenoic acid (DHA) conjugated to PS, and methods of treatment of seizures with same.
摘要翻译：一种用于治疗和/或预防癫痫发作，包括丝氨酸甘油磷脂的非哺乳动物来源的混合物的制备（PS）共轭物，worin该混合物包括（a）二十碳五共轭酸（EPA）与PS结合的和（b）二十二碳六烯酸（DHA）到PS，和治疗癫痫发作相同的方法。

15. 发明公开

EP3457862A1 OIL BLENDS AND PROCESSES FOR THEIR PREPARATION 有权转让
公开(公告)号：EP3457862A1
公开(公告)日：2019-03-27
申请号：EP16759879.6
申请日：2016-08-17
申请人： Enzymotec Ltd.
发明人： WIDBERG, Asher , BEN-DROR, Gai , ILITZKY GUR, Maria , HERZOG, Yael
IPC分类号： A23D9/04 , A23L33/115 , A23L33/00 , A61K8/92

16. 发明公开

EP3171706A1 NUTRITIONAL COMPOSITIONS CONTAINING PHOSPHATIDYLSERINE POWDER 有权转让
标题翻译：含有磷脂酰丝氨酸粉末的营养组合物
公开(公告)号：EP3171706A1
公开(公告)日：2017-05-31
申请号：EP15781413.8
申请日：2015-07-23
申请人： Enzymotec Ltd.
发明人： WIDBERG, Asher , HERZOG, Yael
IPC分类号： A23J7/00 , C07F9/10
CPC分类号： A61K31/685 , A23G3/40 , A23J7/00 , A23L33/00 , A23L33/10 , A23L33/40 , A23V2002/00 , A61K9/1611 , C07F9/103
摘要： Phosphatidylserine powder compositions of the present invention were found to provide more homogeneous dispersion and demonstrate reduced sedimentation, compared to conventional phosphatidylserine powders, when mixed without processing by high pressure homogenization in water or other liquids. The composition of the present invention comprises phosphatidylserine and at least 80% (w/w) of the composition has a particle size of 500 microns or less. Nutritional, nutraceutical, or pharmaceutical compositions including the phosphatidylserine powder compositions of the present invention are also provided. Process for preparing phosphatidylserine powder compositions according to the present invention is also provided and includes sieving.
摘要翻译：发现本发明的磷脂酰丝氨酸粉末组合物提供了更均匀的分散，并且与常规磷脂酰丝氨酸粉末相比，当与水或其他液体中的高压均质混合而未经处理混合时，沉降减少。本发明的组合物包含磷脂酰丝氨酸，并且组合物的至少80％（w / w）具有500微米或更小的粒度。还提供了包括本发明的磷脂酰丝氨酸粉末组合物的营养，营养药物或药物组合物。还提供了根据本发明制备磷脂酰丝氨酸粉末组合物的方法，其包括筛分。

17. 发明公开

EP3426062A1 LIPID COMPOSITIONS AND USES THEREOF 审中-实审转让
公开(公告)号：EP3426062A1
公开(公告)日：2019-01-16
申请号：EP17714914.3
申请日：2017-03-08
申请人： Enzymotec Ltd.
发明人： BAR-YOSEPH, Fabiana , HERZOG, Yael
IPC分类号： A23L33/12 , A61K31/20 , A61P19/00

18. 发明公开

EP1876913A1 HUMAN MILK FAT SUBSTITUTES 审中-公开
标题翻译： ERSATZPRODUKTEFÜRHUMANES MILCHFETT
公开(公告)号：EP1876913A1
公开(公告)日：2008-01-16
申请号：EP06728308.5
申请日：2006-04-27
申请人： Enzymotec Ltd.
发明人： SHULMAN, Avidor , BEN DROR, Gai , LAOUZ, Hala , YAAKOBI, Dov , BAR-ON, Zohar , BLINDER, Gregory , MEIRI-BENDEK, Iris , HERZOG, Yael
IPC分类号： A23L1/29 , A23D9/00 , C11C3/10 , C11C3/08
CPC分类号： A23D9/00 , A23L33/115 , A23L33/30 , A23L33/40 , A23V2002/00 , C11C3/08 , C11C3/10
摘要： Disclosed are human milk fat (HMF) substitutes, processes for preparation thereof, uses thereof, and fat blends and infant formula containing the HMF substitutes. A fat base composition of the invention includes a mixture of vegetable-derived triglycerides, with less than 50% of the fatty acid residues bonded at the sn-2 position being saturated; and/or with the amount of saturated fatty acid residues bonded at the sn-2 position of the glycerol backbone less than about 43.5% of the total amount of the fatty acid residues. Typically, substantially all of the saturated fatty acids bonded at the sn-2 position of the glycerol backbone are palmitic acid residues. Also disclosed are substitute HMF compositions including a blend of at least 25% or at least 30% of the fat base composition of the invention with up to 75%, or respectively up to 70%, of at least one vegetable oil. Processes for preparing the fat base compositions and blend are also disclosed. Further disclosed are infant formulas including the fat base composition or substitute human milk fat composition.
摘要翻译：公开了人乳脂肪（HMF）替代物，其制备方法，其用途，脂肪混合物和含有HMF替代物的婴儿配方奶粉。本发明的脂肪基组合物包括植物来源的甘油三酯的混合物，其中在sn-2位置处键合的少于50％的脂肪酸残基是饱和的; 和/或与甘油骨架的sn-2位相连的饱和脂肪酸残基的量小于脂肪酸残基总量的约43.5％。通常，在甘油主链的sn-2位上键合的基本上所有的饱和脂肪酸都是棕榈酸残基。还公开了替代HMF组合物，其包括本发明的脂肪基础组合物的至少25％或至少30％的共混物与至多一种植物油的高达75％，或分别高达70％的混合物。还公开了制备脂肪基础组合物和共混物的方法。进一步公开的是包含脂肪基础组合物或替代人乳脂肪组合物的婴儿配方食品。

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