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11. 发明授权

US10364250B2 Bioactive compounds 有权
公开(公告)号：US10364250B2
公开(公告)日：2019-07-30
申请号：US15314258
申请日：2014-05-26
申请人： Mark Barry Hampton , Andrew Ian Selwood , Feng Shi
发明人： Mark Barry Hampton , Andrew Ian Selwood , Feng Shi
IPC分类号： C07D491/22 , A61K31/395 , A61K31/357 , A61K31/4353
摘要： Congener of portimine of the structure: where: R1 is selected from H, acyl, alkyl, alkylene, aryl and aralkyl; R2 is selected from H, acyl, alkyl, alkylene, aryl and aralkyl; M is O, S, N—NH2, N(alkyl)2, N-alkoxy or N(aryl)2; W and X may form a bond, an epoxide, or are independently selected from H, halogen, OH and O-acyl. Y and Z form a bond, an epoxide, or are independently selected from H, halogen (X), OH and O-acyl; and R1 and R2 are not H, M is not O, or W and X or Y and Z do not form a bond.

12. 发明授权

US09957157B2 Fabrication of self assembling nano-structures 有权
公开(公告)号：US09957157B2
公开(公告)日：2018-05-01
申请号：US11857967
申请日：2007-09-19
申请人： Gemunu H. Gunaratne , Girish Nathan , Donald J. Kouri , Pradeep Sharma , Fazle Hussain , Feng Shi
发明人： Gemunu H. Gunaratne , Girish Nathan , Donald J. Kouri , Pradeep Sharma , Fazle Hussain , Feng Shi
IPC分类号： B81C1/00 , B82Y30/00
CPC分类号： B81C1/00031 , B81C2201/0149 , B82Y30/00 , Y10T428/24628
摘要： A new approach to fabricating regularly patterned nano-scale structures, by self assembly of the structures is disclosed, where a pattern of nano-lines are deposited on a substrate and nano-structures are grown by self assembly in regions between the lines to form regular or patterned nano-scale structures, which are ideally suited for the construction nano-scale materials, nano-scale electronic devices and other nano-scale objects, apparatuses or devices. The invention also relates to methods of making and using same.

13. 发明授权

US08962608B2 Cycloalkylnitrile pyrazole carboxamides as janus kinase inhibitors 有权
标题翻译：环烷基腈吡唑甲酰胺作为甘蔗激酶抑制剂
公开(公告)号：US08962608B2
公开(公告)日：2015-02-24
申请号：US14345976
申请日：2012-09-21
申请人： Jason Brubaker , Christopher Dinsmore , Dawn Marie Hoffman , Joon Jung , Duan Liu , Scott Peterson , Tony Siu , Luis E. Torres , Hongjun Zhang , Zhongyong Wei , Feng Shi
发明人： Jason Brubaker , Christopher Dinsmore , Dawn Marie Hoffman , Joon Jung , Duan Liu , Scott Peterson , Tony Siu , Luis E. Torres , Hongjun Zhang , Zhongyong Wei , Feng Shi
IPC分类号： A61K31/397 , A61K31/5377 , A61K31/501 , A61K31/497 , A61K31/415 , C07D231/38 , C07D403/08 , C07D403/12 , C07D405/08 , C07D401/12 , C07D401/14 , C07D405/12 , C07D409/12 , C07D413/12 , C07D401/04 , C07D403/04 , C07D405/04 , C07D401/06 , C07D403/06 , C07D405/06 , C07D405/14 , C07D409/04 , C07D413/14 , C07D417/14
CPC分类号： C07D405/08 , C07D231/38 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/08 , C07D403/12 , C07D405/04 , C07D405/06 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/14
摘要： The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.
摘要翻译：本发明提供了作为JAK抑制剂的式I化合物，因此可用于治疗JAK介导的疾病如类风湿性关节炎，哮喘，COPD和癌症。

14. 发明授权

US08901087B2 Selective glycosidase inhibitors and uses thereof 有权
标题翻译：选择性糖苷酶抑制剂及其用途
公开(公告)号：US08901087B2
公开(公告)日：2014-12-02
申请号：US13883811
申请日：2011-11-08
申请人： Jiang Chang , Kun Liu , Ernest J. McEachern , Changwei Mu , Harold G. Selnick , Feng Shi , David J. Vocadlo , Yaode Wang , Zhongyong Wei , Yuanxi Zhou , Yongbao Zhu
发明人： Jiang Chang , Kun Liu , Ernest J. McEachern , Changwei Mu , Harold G. Selnick , Feng Shi , David J. Vocadlo , Yaode Wang , Zhongyong Wei , Yuanxi Zhou , Yongbao Zhu
IPC分类号： C08B37/00 , C07D487/02 , A61K31/70 , A61K31/425 , C07D513/04
CPC分类号： C07D513/04
摘要： The invention is directed to compounds for selectively inhibiting glycosidases, uses of the compounds and pharmaceutical compositions including the compounds, and methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, and/or accumulation or deficiency of O-GlcNAc.
摘要翻译：本发明涉及用于选择性抑制糖苷酶的化合物，化合物的用途和包含该化合物的药物组合物，以及治疗与O-GlcNAC的缺乏或过度表达有关的疾病和障碍和/或O-GlcNAc的积累或缺陷的方法。

15. 发明授权

US08244301B2 Method of dealing with carrier conflict between main and subordinate cards of single-chip dual-card-dual-standby mobile phone 有权
标题翻译：处理单片双卡双待手机主卡与载卡冲突的方法
公开(公告)号：US08244301B2
公开(公告)日：2012-08-14
申请号：US12334445
申请日：2008-12-13
申请人： Feng Shi
发明人： Feng Shi
IPC分类号： H04M1/00
CPC分类号： H04W48/12 , H04W68/00 , H04W88/02
摘要： The present invention provides a method for dealing with the carrier conflict between the main card and subordinate card of a single-chip dual-card-dual-standby mobile phone, which includes a set one set of antenna, RF module and baseband processing chip and further comprises a radio resource adapter layer provided between the RRC layer and the physical layer. The RRC module calculates the position of the carriers of the main card and the subordinate card. The radio resource adapter layer determines the relative position between the carriers of main card and subordinate card so as to determine the type of the conflict, set priority levels to the services of the main card and subordinate card, and process the services according to the priority levels so as to avoid the conflict.
摘要翻译：本发明提供了一种处理单片双卡双待移动电话的主卡和下卡之间的载波冲突的方法，其包括一组天线，RF模块和基带处理芯片，以及还包括设置在RRC层和物理层之间的无线电资源适配器层。 RRC模块计算主卡和下级卡的载体的位置。无线电资源适配器层确定主卡和从属卡的载体之间的相对位置，以确定冲突的类型，为主卡和从属卡的服务设置优先级，并根据优先级处理服务级别，以避免冲突。

16. 发明申请

US20120021734A1 METHOD FOR RESOLVING CONFLICT BETWEEN NETWORK SEARCHING AND TRAFFIC AND MULTI-CARD MULTI-STANDBY MOBILE PHONE 有权
标题翻译：解决网络搜索与流量与多卡多移动电话之间冲突的方法
公开(公告)号：US20120021734A1
公开(公告)日：2012-01-26
申请号：US13104745
申请日：2011-05-10
申请人： Feng Shi
发明人： Feng Shi
IPC分类号： H04W48/00 , H04W88/02
CPC分类号： H04W48/16 , H04W8/183 , H04W76/28 , H04W88/06
摘要： A method for resolving conflict between network searching and traffic includes: determining if a service request corresponds to mobile originated traffic or mobile terminated traffic, when a second user card receives the service request during a process of the network searching of a first user card; temporarily suspending the mobile originated traffic and continuing to perform the network searching of the first user card, when the service request corresponds to the mobile originated traffic; and temporarily suspending the network searching of the first user card, firstly processing the mobile terminated traffic, and continuing to perform the network searching of the first user card after completing the mobile terminated traffic, when the service request corresponds to the mobile terminated traffic. A multi-card multi-standby mobile phone of the present invention includes at least two types of user card, a communication unit for transmitting communication information, a microcontroller unit and a determining unit. The present invention avoids impact of the network searching to the mobile originated traffic and the mobile terminated traffic.
摘要翻译：一种用于解决网络搜索与流量之间的冲突的方法包括：当在第一用户卡的网络搜索过程中第二用户卡接收到服务请求时，确定服务请求是否对应于移动发起的流量或移动终止的流量; 当服务请求对应于移动发起的业务时，暂时中止移动发起的流量并继续执行第一用户卡的网络搜索; 并暂时中止第一用户卡的网络搜索，首先处理移动终端业务，并且当业务请求对应于移动终端流量时，在完成移动终止业务之后继续执行第一用户卡的网络搜索。本发明的多卡多待机手机包括至少两种用户卡，用于发送通信信息的通信单元，微控制器单元和确定单元。本发明避免了网络搜索对移动起始业务和移动终端流量的影响。

17. 发明授权

US07382958B1 Photonic crystal wave guide optical spectrometer 失效
标题翻译：光子晶体波导光谱仪
公开(公告)号：US07382958B1
公开(公告)日：2008-06-03
申请号：US11593228
申请日：2006-11-06
申请人： Feng Shi
发明人： Feng Shi
IPC分类号： G02B6/02
CPC分类号： G01J3/02 , G01J3/0205 , G01J3/0218 , G01J3/0256 , G01J2003/1213 , G02B6/02304 , G02B6/02328 , G02B6/29304
摘要： An optical instrument for splitting optical spectrum, comprising a series of hollow core optical wave guides (12, 22, and so on) connected by optical couplers (16, 26, and so on) transporting broad band incident optical wave from one stage to another, a narrow band optical wave guide (14, 24, and so on) made of photonic crystal materials mounted inside each of said hollow core optical wave guide and along it, and specified for confining certain portion of the incident optical spectrum. Said inner narrow band optical wave guides bend out at the ends of said outer hollow core optical wave guides to extract and guide out the selected component of the incident optical spectrum. Said optical couplers couple the output optical waves of said outer hollow core wave guides of the previous stages into said inner optical wave guides of the next stages for further splitting.
摘要翻译：一种用于分离光谱的光学仪器，包括通过光束耦合器（16,26等）连接的一系列空心光纤光波导（12,22等），其将宽带入射光波从一个级传输到另一级，安装在每个所述中空芯光波导内并沿着它的光子晶体材料制成的窄带光波导（14,24等），并且用于限制入射光谱的某一部分。所述内窄带光波导在所述外空心芯光波导的端部弯曲，以提取并引出入射光谱的选定分量。所述光耦合器将先前级的所述外部中空芯波导的输出光波耦合到下一级的所述内部光波导中，以进一步分裂。

18. 发明申请

US20070036289A1 VOICE AUTHENTICATION SYSTEM AND METHOD USING A REMOVABLE VOICE ID CARD 有权
标题翻译：语音认证系统和使用可移动语音识别卡的方法
公开(公告)号：US20070036289A1
公开(公告)日：2007-02-15
申请号：US11424627
申请日：2006-06-16
申请人： Guo Fu , Feng Shi , Zhi Wang , Yu Zhou
发明人： Guo Fu , Feng Shi , Zhi Wang , Yu Zhou
IPC分类号： H04M1/64
CPC分类号： H04L63/0861 , G07C9/00158 , G10L17/00 , H04M3/385 , H04M2201/41 , H04M2203/553 , H04M2203/554
摘要： A voice authentication system using a removable voice ID card comprises: at server side, a voiceprint database for storing the voiceprints of all authorized users; a voiceprint updating means for updating the voiceprints in said voiceprint database; and a voiceprint digest generator for generating a voiceprint digest according to a request from a client; at client side, a voice ID card for storing the voiceprint of an authorized user; a validation means for validating the voiceprint in the voice ID card on the basis of the voiceprint digest from the server; an audio device for performing voice interaction with a user; and a voice authentication means for determining whether the voiceprint from said voice ID card is of the same speaker as the voice from said audio device. The present invention can significantly avoid the abuse of a voice ID card when it is lost or stolen by using the voiceprint digest stored at server side to verify the voiceprint in the voice ID card.
摘要翻译：一种使用可移动语音识别卡的语音认证系统包括：在服务器侧，用于存储所有授权用户的声纹的声纹数据库; 声纹更新装置，用于更新所述声纹数据库中的声纹; 以及声纹摘要生成器，用于根据客户端的请求生成声纹摘要; 在客户侧，存储用于存储授权用户的声纹的语音ID卡; 验证装置，用于基于来自服务器的声纹摘要来验证语音ID卡中的声纹; 用于与用户进行语音交互的音频设备; 以及语音认证装置，用于确定来自所述语音ID卡的声纹是否与来自所述音频设备的语音具有相同的扬声器。本发明可以通过使用存储在服务器端的声纹摘要丢失或被盗，来大大地避免语音ID卡的滥用来验证语音ID卡中的声纹。

19. 发明授权

US07027135B2 Optical circuits for tunable second order PMD compensation and tunable dispersion compensation 有权
公开(公告)号：US07027135B2
公开(公告)日：2006-04-11
申请号：US10157901
申请日：2002-05-31
申请人： Xiaoli Fu , Genzao Zhang , Tongqing Wang , Feng Shi
发明人： Xiaoli Fu , Genzao Zhang , Tongqing Wang , Feng Shi
IPC分类号： G01N21/00
CPC分类号： G02B6/29394 , G02B6/272 , G02B6/274 , G02B6/278 , G02B6/29395 , H04B10/2569
摘要： A method and an apparatus is provided for introducing tunable second order polarization mode dispersion compensation to an optical signal without introducing any first order polarization mode dispersion into the optical signal. A method and an apparatus is also provided for tunable chromatic dispersion compensation by rotating the polarization state of an input signal to match the chromatic like second order PMD compensation provided by the present invention. In one configuration, birefringent elements are arranged into at least two stages, each stage having at least two birefringent elements, each birefringent element of one stage oriented orthogonal to a corresponding birefringent element of a corresponding stage. In another configuration, the polarization of optical signals emerging from each birefringent element are rotated to create effective orthogonal orientations between corresponding birefringent elements of corresponding stages.

20. 发明授权

US09394282B2 Pyrazole carboxamides as Janus kinase inhibitors 有权
标题翻译：吡唑甲酰胺作为Janus激酶抑制剂
公开(公告)号：US09394282B2
公开(公告)日：2016-07-19
申请号：US14345982
申请日：2012-09-21
申请人： Jason Brubaker , Joshua Close , Tony Siu , Graham Frank Smith , Luis E. Torres , Hyun Chong Woo , Jonathan R. Young , Zhongyong Wei , Feng Shi
发明人： Jason Brubaker , Joshua Close , Tony Siu , Graham Frank Smith , Luis E. Torres , Hyun Chong Woo , Jonathan R. Young , Zhongyong Wei , Feng Shi
IPC分类号： C07D401/04 , C07D405/14 , C07D409/04 , C07D417/14 , C07D405/04 , C07D413/14 , C07D401/14 , C07D405/08 , C07D403/12 , C07D231/38 , C07D401/12 , C07D403/08 , C07D405/12 , C07D409/12 , C07D413/12 , C07D403/04 , C07D401/06 , C07D403/06 , C07D405/06
CPC分类号： C07D405/08 , C07D231/38 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/08 , C07D403/12 , C07D405/04 , C07D405/06 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/14
摘要： The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.
摘要翻译：本发明提供了作为JAK抑制剂的式I化合物，因此可用于治疗JAK介导的疾病如类风湿性关节炎，哮喘，COPD和癌症。

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