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11. 发明申请

WO2019018341A1 RANGE COMPENSATORS FOR RADIATION THERAPY 审中-公开
公开(公告)号：WO2019018341A1
公开(公告)日：2019-01-24
申请号：PCT/US2018/042389
申请日：2018-07-17
申请人： VARIAN MEDICAL SYSTEMS, INC.
发明人： ABEL, Eric , ZANKOWSKI, Corey
IPC分类号： A61N5/10
摘要： A system for treating a patient during radiation therapy includes range compensators. Each of the range compensators shapes a distribution of a dose delivered to the patient by a beam emitted from a nozzle of a radiation treatment system. A positioning component holds the range compensator in place relative to the patient such that the range compensator lies on a path of the beam.

12. 发明申请

WO2017059086A1 HIGH DQE IMAGING DEVICE 审中-公开
标题翻译：高DQE成像装置
公开(公告)号：WO2017059086A1
公开(公告)日：2017-04-06
申请号：PCT/US2016/054472
申请日：2016-09-29
申请人： VARIAN MEDICAL SYSTEMS, INC.
发明人： SHEDLOCK, Daniel , STAR-LACK, Josh M. , MORF, Daniel , ABEL, Eric , VIRSHUP, Gary F. , MEYER, Andre , STEINLIN, Viktor , SUN, Mingshan
IPC分类号： G01T1/20 , A61B6/00 , A61B6/03 , G01T1/00 , G01T1/16
CPC分类号： G01T1/2018 , G01T1/2002
摘要： An imaging device includes: a scintillator layer; and an array of photodiode elements; wherein the scintillator layer is configured to receive radiation that has passed through the array of photodiode elements. An imaging device includes: a scintillator layer having a plurality of scintillator elements configured to convert radiation into photons; and an array of photodiode elements configured to receive photons from the scintillator layer, and generate electrical signals in response to the received photons; wherein at least two of the scintillator elements are separated by an air gap. An imaging device includes: a first scintillator layer having a plurality of scintillator elements arranged in a first plane; and a second scintillator layer having a plurality of scintillator elements arranged in a second plane; wherein the first scintillator layer and the second scintillator layer are arranged next to each other and form a non-zero angle relative to each other.
摘要翻译：一种成像装置包括：闪烁体层; 和一组光电二极管元件; 其中所述闪烁体层被配置为接收已经通过所述光电二极管元件阵列的辐射。一种成像装置包括：具有多个闪烁体元件的闪烁体层，其被配置为将辐射转换成光子; 以及配置成从闪烁体层接收光子的光电二极管元件的阵列，并且响应于所接收的光子而产生电信号; 其中所述闪烁体元件中的至少两个由气隙分开。一种成像装置包括：具有布置在第一平面中的多个闪烁体元件的第一闪烁体层; 以及第二闪烁体层，其具有布置在第二平面中的多个闪烁体元件; 其中所述第一闪烁体层和所述第二闪烁体层彼此相邻布置并且相对于彼此形成非零角度。

13. 发明申请

WO2021198453A1 SYSTEM AND METHOD FOR SCANNING PATTERN OPTIMIZATION FOR FLASH THERAPY TREATMENT PLANNING 审中-公开
公开(公告)号：WO2021198453A1
公开(公告)日：2021-10-07
申请号：PCT/EP2021/058682
申请日：2021-04-01
申请人： VARIAN MEDICAL SYSTEMS INTERNATIONAL AG , VARIAN MEDICAL SYSTEMS PARTICLE THERAPY GMBH & CO. KG , VARIAN MEDICAL SYSTEMS INC
发明人： PEREZ, Jessica , KOPONEN, Timo , ROSSI, Michiko , VANDERSTRAETEN, Reynald , ABEL, Eric , FOLKERTS, Michael , SMITH, Christel , HARRINGTON, Adam , MAGLIARI, Anthony
IPC分类号： A61N5/10 , A61N2005/1012 , A61N2005/1087 , A61N5/1007 , A61N5/103 , A61N5/1031
摘要： Embodiments of the present invention provide methods and systems for proton therapy planning that maximize the dose rate for different target sizes for FLASH therapy treatment are disclosed herein according to embodiments of the present invention. According to embodiments, non-standard scanning patterns can be generated, for example, using a TPS optimizer, to maximize dose rate and the overall FLASH effect for specific volumes at risk. The novel scanning patterns can include scanning subfields of a field that are scanned independently or spiral-shaped patterns, for example. In general, spot locations and beam paths between spots are optimized 503 to substantially achieve a desired dose rate in defined regions of the patient's body for FLASH therapy treatment.

14. 发明申请

WO2020249565A1 A FLASH THERAPY TREATMENT PLANNING AND ONCOLOGY INFORMATION SYSTEM HAVING DOSE RATE PRESCRIPTION AND DOSE RATE MAPPING 审中-公开
公开(公告)号：WO2020249565A1
公开(公告)日：2020-12-17
申请号：PCT/EP2020/065983
申请日：2020-06-09
申请人： VARIAN MEDICAL SYSTEMS INTERNATIONAL AG , VARIAN MEDICAL SYSTEMS, INC. , VARIAN MEDICAL SYSTEMS PARTICLE THERAPY GMBH.
发明人： KOPONEN, Timo , ABEL, Eric , MAGLIARI, Anthony , SMITH, Christel , FOLKERTS, Michael , VANDERSTRAETEN, Reynald , KHUNTIA, Deepak , PEREZ, Jessica
IPC分类号： A61N5/10
摘要： A computing system comprising a central processing unit (CPU), and memory coupled to the CPU and having stored therein instructions that, when executed by the computing system, cause the computing system to execute operations to generate a radiation treatment plan. The operations include accessing (502) a minimum prescribed dose to be delivered into and across the target, determining (504, 506) a number of beams and directions of the beams, and determining a beam energy for each of the beams, wherein the number of beams, the directions of the beams, and the beam energy for each of the beams are determined such that the entire target receives the minimum prescribed dose. The operations further include prescribing a dose rate and optimizing dose rate constraints for FLASH therapy, and displaying a dose rate map of the FLASH therapy.

15. 发明申请

WO2020249513A1 MATERIAL INSERTS FOR RADIATION THERAPY 审中-公开
公开(公告)号：WO2020249513A1
公开(公告)日：2020-12-17
申请号：PCT/EP2020/065841
申请日：2020-06-08
申请人： VARIAN MEDICAL SYSTEMS INTERNATIONAL AG , VARIAN MEDICAL SYSTEMS, INC. , VARIAN MEDICAL SYSTEMS PARTICLE THERAPY GMBH.
发明人： PEREZ, Jessica , KOPONEN, Timo , ABEL, Eric , ZANKOWSKI, Corey , MAGLIARI, Anthony , SMITH, Christel , FOLKERTS, Michael , HANSEN, Bill , VANDERSTRAETEN, Reynald
IPC分类号： A61N5/10
摘要： A system for treating a patient during radiation therapy is disclosed. The system includes a shell 1105, a plurality of material inserts 1110 disposed in the shell, where each material insert of the plurality of material inserts respectively shapes a distribution of a dose delivered to the patient by a respective beam of a plurality of beams emitted from a nozzle of a radiation treatment system, and a scaffold 1115 component disposed in the shell that holds the plurality material inserts in place relative to the patient such that each material insert lies on a path of at least one of the beams.

16. 发明申请

WO2020181036A2 GRAPHICAL DISPLAY OF DOSE RATE INFORMATION FOR RADIATION TREATMENT PLANNING 审中-公开
公开(公告)号：WO2020181036A2
公开(公告)日：2020-09-10
申请号：PCT/US2020/021091
申请日：2020-03-05
申请人： VARIAN MEDICAL SYSTEMS, INC.
发明人： KHUNTIA, Deepak , VERTATSCHITSCH, Edward , ABEL, Eric , MAGLIARI, Anthony , SMITH, Christel
IPC分类号： A61N5/10

17. 发明申请

WO2020180994A1 RADIATION TREATMENT PLANNING BASED ON DOSE RATE 审中-公开
公开(公告)号：WO2020180994A1
公开(公告)日：2020-09-10
申请号：PCT/US2020/021005
申请日：2020-03-04
申请人： VARIAN MEDICAL SYSTEMS, INC.
发明人： KHUNTIA, Deepak , VERTATSCHITSCH, Edward , ABEL, Eric , MAGLIARI, Anthony , SMITH, Christel
IPC分类号： A61N5/10
摘要： A dose rate-volume histogram is generated for a target volume. The dose rate-volume histogram can be stored in computer system memory and used to generate a radiation treatment plan. An irradiation time-volume histogram can also be generated for the target volume. The irradiation time-volume histogram can be stored in computer system memory and used to generate the radiation treatment plan.

18. 发明申请

WO2019016305A1 DOSE ASPECTS OF RADIATION THERAPY PLANNING AND TREATMENT 审中-公开
公开(公告)号：WO2019016305A1
公开(公告)日：2019-01-24
申请号：PCT/EP2018/069605
申请日：2018-07-19
申请人： VARIAN MEDICAL SYSTEMS INTERNATIONAL AG , VARIAN MEDICAL SYSTEMS INC
发明人： VANDERSTRATEN, Reynald , ABEL, Eric , SMITH, Christel , MAGLIARI, Anthony , KOPONEN, Timo , MANSFIELD, Stanley , ADELSHEIM, Charles
IPC分类号： A61N5/10
摘要： Radiation treatment planning includes accessing values of parameters such as a number of beams to be directed into sub-volumes in a target, beam directions, and beam energies. Information that specifies limits for the radiation treatment plan are accessed. The limits include a limit on irradiation time for each sub-volume outside the target. Other limits can include a limit on irradiation time for each sub-volume in the target, a limit on dose rate for each sub-volume in the target, and a limit on dose rate for each sub-volume outside the target. The values of the parameters are adjusted until the irradiation time for each sub-volume outside the target satisfies the maximum limit on irradiation time.

19. 发明公开

EP4168112A1 DEFINING DOSE RATE FOR PENCIL BEAM SCANNING 审中-实审
公开(公告)号：EP4168112A1
公开(公告)日：2023-04-26
申请号：EP21736839.8
申请日：2021-06-08
申请人： Varian Medical Systems, Inc.
发明人： FOLKERTS, Michael , ABEL, Eric , BUSOLD, Simon , PEREZ, Jessica , KRISHNAMURTHI, Vidhya , LING, C., Clifton
IPC分类号： A61N5/10

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