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11. 发明申请

US20090035746A1 Device and Method for Preparing a Sample for an Analysis and Device and Method for Analyzing a Sample 审中-公开
标题翻译：用于分析样品准备样品的装置和方法以及用于分析样品的方法
公开(公告)号：US20090035746A1
公开(公告)日：2009-02-05
申请号：US11922879
申请日：2006-06-21
申请人： Thomas Ehben , Christian Zilch
发明人： Thomas Ehben , Christian Zilch
IPC分类号： C12Q1/00 , C12M1/00 , C12N13/00 , C12P19/34
CPC分类号： B01L3/502761 , B01L7/52 , B01L2200/0647 , B01L2300/0816 , B01L2300/087 , B01L2300/1822 , B01L2400/043 , G01N35/0098
摘要： A device and method are disclosed for preparing a sample for an analysis and a device and method are disclosed for analyzing a sample. In at least one embodiment, a device is disclosed for preparing a sample for analysis including means for binding at lest one biological structure of the sample, means for releasing at least one biological molecule contained in the at least one structure, and means for binding the at least one released molecule. The means for binding the at least one structure and the means for binding the at least one molecule can move.
摘要翻译：公开了一种用于制备用于分析的样品的装置和方法，并且公开了用于分析样品的装置和方法。在至少一个实施方案中，公开了用于制备用于分析的样品的装置，包括用于结合样品的至少一个生物结构的装置，用于释放至少一个结构中包含的至少一个生物分子的装置，以及用于结合至少一个释放的分子。用于结合所述至少一种结构的方法和用于结合至少一种分子的方法可移动。

12. 发明申请

US20090081650A1 Method for Identifying Nucleotide Sequences, Use of the Method and Test Kit 审中-公开
标题翻译：识别核苷酸序列的方法，方法和测试试剂盒的使用
公开(公告)号：US20090081650A1
公开(公告)日：2009-03-26
申请号：US11922876
申请日：2006-06-22
申请人： Thomas Ehben , Christian Zilch
发明人： Thomas Ehben , Christian Zilch
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6837 , C12Q1/686 , C12Q2565/537 , C12Q2531/107 , C12Q2527/137
摘要： A method is disclosed for identifying nucleotide sequences while using non-labeled free oligonucleotides, labeled free and hybridizable oligonucleotides and non-labeled and immobilized oligonucleotides.
摘要翻译：公开了用于鉴定核苷酸序列同时使用非标记的游离寡核苷酸，标记的游离和可杂交的寡核苷酸和未标记和固定的寡核苷酸的方法。

13. 发明申请

US20080193926A1 Device and method for extracting a smear sample 有权
标题翻译：用于提取涂片样品的装置和方法
公开(公告)号：US20080193926A1
公开(公告)日：2008-08-14
申请号：US11599424
申请日：2006-11-15
申请人： Klaus Abraham-Fuchs , Thomas Ehben , Walter Gumbrecht , Peter Paulicka , Sebastian Schmidt , Manfred Stanzel , Christian Zilch
发明人： Klaus Abraham-Fuchs , Thomas Ehben , Walter Gumbrecht , Peter Paulicka , Sebastian Schmidt , Manfred Stanzel , Christian Zilch
IPC分类号： C12M1/26 , C12Q1/68
CPC分类号： B01L3/502715 , A61B10/0051 , A61B10/0096 , B01L3/502738 , B01L3/502761 , B01L3/5029 , B01L2200/027 , B01L2300/042 , B01L2400/0478 , B01L2400/0633 , G01N2001/028
摘要： A device is disclosed for extracting a smear sample. The device includes a cavity, into which a sample carrier carrying a smear sample can be introduced. Liquid can be introduced into the cavity through at least one liquid feed connected to the cavity, and the liquid can be removed from the cavity through at least one liquid discharge connected to the cavity.
摘要翻译：公开了一种用于提取涂片样品的装置。该装置包括可以引入携带涂片样品的样品载体的空腔。可以通过连接到空腔的至少一个液体进料将液体引入空腔中，并且可以通过连接到空腔的至少一个液体排出物从腔中去除液体。

14. 发明申请

US20080182338A1 Apparatus and process for processing a sample 有权
标题翻译：用于处理样品的装置和方法
公开(公告)号：US20080182338A1
公开(公告)日：2008-07-31
申请号：US11594938
申请日：2006-11-09
申请人： Klaus Abraham-Fuchs , Thomas Ehben , Walter Gumbrecht , Sebastian Schmidt , Christian Zilch
发明人： Klaus Abraham-Fuchs , Thomas Ehben , Walter Gumbrecht , Sebastian Schmidt , Christian Zilch
IPC分类号： G01N1/28 , B01J19/00 , C12M1/40
CPC分类号： G01N1/42 , G01N2035/00148 , Y10T436/25
摘要： An apparatus is disclosed for processing a sample which stores processing reagents required for processing in a dry form. The processing reagents are covered by a biologically degradable medium or embedded in said biologically degradable medium.
摘要翻译：公开了一种用于处理以干燥形式存储处理所需的处理试剂的样品的装置。处理试剂被生物降解介质覆盖或嵌入所述生物降解介质中。

15. 发明申请

US20080020453A1 Analytical system based on porous material for highly parallel single cell detection 审中-公开
标题翻译：基于多孔材料的分析系统用于高度并行单细胞检测
公开(公告)号：US20080020453A1
公开(公告)日：2008-01-24
申请号：US11878088
申请日：2007-07-20
申请人： Thomas Ehben , Christian Zilch
发明人： Thomas Ehben , Christian Zilch
IPC分类号： C12M1/33 , C12M1/34
CPC分类号： B01L3/5025 , B01L3/50851 , B01L3/50853 , B01L3/50857 , B01L7/52 , B01L2200/0647 , B01L2300/045 , B01L2300/046 , B01L2300/0819 , B01L2300/1827 , C12M47/04 , C12M47/06 , C12M47/12
摘要： At least one embodiment of the present invention relates to analytical systems based on porous material, for example silicon, for highly parallel single cell detection. At least one embodiment of the present invention relates in particular to porous silicon having a multiplicity of continuous channels and/or to the use thereof at least for cell separation, for cell lysis and purification of target molecules, for amplification of nucleic acid molecules or for detection of desired target molecules. At least one embodiment of the present invention also relates to an analytical method using porous silicon. Monoclonal antibodies for cell separation and immobilized capture molecules for cell lysis and purification are attached to the inside walls of the channels.
摘要翻译：本发明的至少一个实施方案涉及基于多孔材料（例如硅）的分析系统，用于高度平行的单细胞检测。本发明的至少一个实施方案具体涉及具有多个连续通道的多孔硅和/或其至少用于细胞分离，细胞裂解和纯化靶分子，用于扩增核酸分子或用于检测所需的靶分子。本发明的至少一个实施方案还涉及使用多孔硅的分析方法。用于细胞分离的单克隆抗体和用于细胞裂解和纯化的固定化捕获分子附着在通道的内壁上。

16. 发明申请

US20070166192A1 Module for processing a biological sample, biochip kit, and use of the module 有权
标题翻译：用于处理生物样品的模块，生物芯片套件和模块的使用
公开(公告)号：US20070166192A1
公开(公告)日：2007-07-19
申请号：US11653230
申请日：2007-01-16
申请人： Thomas Ehben , Walter Gumbrecht , Manfred Stanzel , Christian Zilch
发明人： Thomas Ehben , Walter Gumbrecht , Manfred Stanzel , Christian Zilch
IPC分类号： G01N21/00
CPC分类号： G01N1/40 , B01L3/502715 , B01L3/565 , B01L2200/027 , B01L2300/0816 , G01N35/0098 , Y10T436/2575
摘要： A module for processing a biological sample for an analysis test is disclosed. The processing module includes, in at least one embodiment, an interface at which the processing module can be connected to a cartridge with a lab-on-a-chip, in which cartridge the analysis steps are carried out. A biochip kit is also disclosed. In at least one embodiment, the biochip kit includes one or more processing modules which are intended for different sample materials and which can be connected to the same cartridge type.
摘要翻译：公开了用于处理用于分析测试的生物样品的模块。处理模块在至少一个实施例中包括接口，在该界面处，处理模块可以与芯片上的实验室连接，其中进行分析步骤。还公开了一种生物芯片套件。在至少一个实施例中，生物芯片套件包括一个或多个处理模块，其用于不同的样品材料并且可以连接到相同的盒式。

17. 发明申请

US20120158371A1 Method of Assisting Planning of a Technical System 审中-公开
标题翻译：协助技术体系规划的方法
公开(公告)号：US20120158371A1
公开(公告)日：2012-06-21
申请号：US13393182
申请日：2010-08-17
申请人： Thomas Ehben , Thilo Tetzner
发明人： Thomas Ehben , Thilo Tetzner
IPC分类号： G06F17/50
CPC分类号： G05B19/4188 , G05B2219/31343 , G06Q10/06 , Y02P90/20 , Y02P90/205 , Y02P90/24
摘要： A method or a software application which is used to assign artifacts of technical systems to the process steps required to produce them, wherein the assignments comprise annotations, and the method provides an editor for the annotations. A graphical user interface is also provided, which can be used to visualize the artifacts (e.g., documents describing structural elements) of the technical system and individual process steps (or entire process cycles) and to input the annotations between the two in graphical or tabular form and process them. Pre-existing special knowledge in the domain and the craft relating to plant engineering is acquired, processed, preserved and imparted using the method of the invention. The method advantageously provides effective support for document and configuration management, where CAD and project management tools are integrated to give a systematic IT landscape without media clashes.
摘要翻译：一种用于将技术系统的工件分配给生成它们所需的处理步骤的方法或软件应用，其中分配包括注释，并且该方法为注释提供编辑器。还提供了图形用户界面，其可用于可视化技术系统和各个处理步骤（或整个处理循环）的工件（例如，描述结构元件的文档），并以图形或表格方式在两者之间输入注释形成和处理它们。采用本发明的方法获得，处理，保存和传授与工厂工程相关的领域和工艺中的现有专业知识。该方法有利地为文档和配置管理提供了有效的支持，其中CAD和项目管理工具被集成以给出系统的IT环境而没有媒体冲突。

18. 发明申请

US20120158386A1 METHOD FOR THE INSPECTION OF THE MODELING OF TECHNICAL SYSTEMS 审中-公开
标题翻译：检查技术系统建模的方法
公开(公告)号：US20120158386A1
公开(公告)日：2012-06-21
申请号：US13392752
申请日：2010-07-29
申请人： Thomas Ehben , Nasser Jazdi , Camelia Maga , Thilo Tetzner
发明人： Thomas Ehben , Nasser Jazdi , Camelia Maga , Thilo Tetzner
IPC分类号： G06F17/50
CPC分类号： G06F8/10
摘要： Methods and engineering systems for the automatic inspection of the modeling of technical systems in an engineering or design process, wherein the used description language (e.g., UML or SysML) is extended by suitably defined stereotypes, especially suitable for the automatic detection of incompatibilities in the formation or variants of technical systems or products.
摘要翻译：用于自动检查工程或设计过程中技术系统建模的方法和工程系统，其中所使用的描述语言（例如，UML或SysML）通过适当定义的定型扩展，特别适合于自动检测不兼容性技术系统或产品的形成或变体。

19. 再颁专利

USRE39124E1 Integrated circuit having capacitive elements 有权
公开(公告)号：USRE39124E1
公开(公告)日：2006-06-13
申请号：US10625706
申请日：2003-07-23
申请人： Thomas Ehben , Thomas Steinecke , Jens Rosenbusch
发明人： Thomas Ehben , Thomas Steinecke , Jens Rosenbusch
IPC分类号： H01L29/00 , H01L29/94 , H01L31/119 , H01L27/108 , H01L29/76
CPC分类号： H01L23/5223 , H01L23/5222 , H01L23/66 , H01L27/0805 , H01L2924/0002 , H01L2924/3011 , H01L2924/00
摘要： An integrated circuit having capacitive elements for smoothing a supply voltage is described. In this case, at least one additional metal electrode, which is configured as a high frequency-optimized capacitance and is distinguished by an extremely low sheet resistance, is connected in parallel with the MOS capacitances. By connecting the areally highly effective MOS capacitance, which, however, is connected with a somewhat higher impedance, in parallel with areally less effective metal capacitances, which, however, are connected to the supply voltage in a very low-impedance manner, it is possible to obtain broadband buffering and thus decoupling of high-frequency interference signals. Very high-frequency interference components are attenuated on the chip and do not pass into the system surrounding the integrated circuit.

20. 发明申请

US20050057356A1 Warning system and method for monitoring the availability of medical aids for a patient 失效
标题翻译：用于监测患者医疗辅助设备可用性的警告系统和方法
公开(公告)号：US20050057356A1
公开(公告)日：2005-03-17
申请号：US10930120
申请日：2004-08-31
申请人： Thomas Ehben , Michael Mankopf
发明人： Thomas Ehben , Michael Mankopf
IPC分类号： G08B13/14 , G08B21/18 , G08B21/24 , G08B23/00 , G08B1/08
CPC分类号： G08B21/24 , G08B13/1427 , G08B21/0247 , G08B21/0258
摘要： The present invention relates to a warning system and a method for monitoring the availability of medical aids for a patient. The warning system comprises a first signal transmitter, which can be mounted on the aid or on a container for the aid or can be integrated in the aid or container and which has a transmission unit for transmitting first electromagnetic signals, and a second signal transmitter which can be worn by the patient and which has a warning device for outputting a warning signal which can be perceived by the patient, a reception unit for receiving the first electromagnetic signals transmitted by the transmission unit in the first signal transmitter, and a control unit which, when the first electromagnetic signals are received or when a prescribable reception strength for the first electromagnetic signals is undershot and/or when a particular item of information transmitted with the first electromagnetic signals is received, actuates the warning device to output the warning signal. The present warning system reliably draws a patient's attention to when medical aids which are important to him are no longer directly available.
摘要翻译：本发明涉及一种用于监测患者的医疗辅助装置的可用性的警告系统和方法。警告系统包括第一信号发射器，其可以安装在辅助装置上或在容器上用于辅助或可以集成在辅助或容器中，并且具有用于传输第一电磁信号的传输单元和第二信号发射器可以由患者佩戴，并且具有用于输出可由患者感知的警告信号的警告装置，用于接收由第一信号发送器中的发送单元发送的第一电磁信号的接收单元和控制单元，当接收到第一电磁信号时，或者当接收到第一电磁信号的规定的接收强度和/或当接收到用第一电磁信号发送的特定信息项时，启动警告装置输出警告信号。目前的警告系统可靠地吸引患者注意，对他重要的医疗辅助设备不再可直接使用。

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