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11. 发明申请

WO1996033763A2 HIGH PERFORMANCE BRAIDED CATHETER 审中-公开
标题翻译：高性能BRAIDED CATHETER
公开(公告)号：WO1996033763A2
公开(公告)日：1996-10-31
申请号：PCT/US1996005839
申请日：1996-04-26
申请人： TARGET THERAPEUTICS, INC.
发明人： TARGET THERAPEUTICS, INC. , SAMSON, Gene , CHEE, U., Hiram , NGUYEN, Kim , SNYDER, Edward, J. , ENGELSON, Erik, T.
IPC分类号： A61M25/00
CPC分类号： A61M25/005 , A61M25/0053 , A61M25/0054 , A61M2025/0081
摘要： This a catheter assembly and a section of that catheter assembly. That catheter assembly may be used in accessing a tissue target within the body, typically a target which is accessible through the vascular system. Central to the invention is the use of a braided metallic reinforcing member, typically of superelastic alloy ribbon, situated within the catheter body in such a way to create a catheter having an exceptionally thin wall, controlled stiffness, high resistance to kinking, and complete recovery in vivo from kinking situations. The braid may have a single pitch or may vary in pitch along the axis of the catheter or catheter section. The braided ribbon reinforcing member typically is placed between a flexible outer tubing member and an inner tubing member to produce a catheter section which is very flexible but highly kink resistant. The catheter sections made according to this invention may be used alone or in conjunction with other catheter sections either made using the concepts shown herein or made in other ways. The more proximal sections of the catheter assembly are often substantially stiffer than the more distal sections due to the presence of stiff polymeric tubing or metallic tubing or composite materials in the stiffer section.
摘要翻译：这是导管组件和该导管组件的一部分。该导管组件可用于进入体内的组织靶，通常是通过血管系统可接近的靶。本发明的中心是使用位于导管主体内的编织金属加强构件，通常为超弹性合金带，以便产生具有特别薄壁，受控刚度，高耐扭结和完全恢复的导管在体内从扭结的情况。编织物可以具有单个间距，或者可以沿着导管或导管部分的轴线变化。编织带加强构件通常放置在柔性外管构件和内管构件之间以产生非常柔性但高度扭结的导管部分。根据本发明制造的导管部分可以单独使用或与使用本文所示的概念或以其他方式制成的其它导管部分结合使用。由于在刚性部分中存在刚性聚合物管或金属管或复合材料，导管组件的较近的部分通常比较远的部分更坚硬。

12. 发明申请

WO1994027668A1 VARIABLE STIFFNESS BALLOON CATHETER 审中-公开
标题翻译：可变刚度气球导管
公开(公告)号：WO1994027668A1
公开(公告)日：1994-12-08
申请号：PCT/US1994005679
申请日：1994-05-20
申请人： TARGET THERAPEUTICS, INC. , ENGELSON, Erik, T.
发明人： TARGET THERAPEUTICS, INC.
IPC分类号： A61M29/00
CPC分类号： A61M29/02 , A61M25/0045 , A61M25/0054 , A61M2025/0079 , A61M2025/1063
摘要： This invention is a single-lumen balloon catheter (12) and assembly having a variable stiffness shaft that allows for greater guidewire (13) trackability and proximal pushability than previous designs. The catheter (12) has an elongate tubular body that is made of inner (19, 20) and outer (18) coaxial tubes, the inner tube (19, 20) being made of proximal and distal sections, the proximal section (19) being stiffer than the distal section (20) and the distal section (20) being stiffer than the outer tube (18).
摘要翻译：本发明是一种具有可变刚度轴的单腔气囊导管（12）和组件，其允许比以前的设计更大的导丝（13）跟踪性和近端推挤性。所述导管（12）具有由内部（19,20）和外部（18）同轴管制成的细长管状体，所述内部管（19,20）由近端和远端部分制成，所述近端部分（19）比所述远端部分（20）更硬，并且所述远端部分（20）比所述外管（18）更硬。

13. 发明申请

WO1994026341A1 DRUG DELIVERY SYSTEM 审中-公开
标题翻译：药物递送系统
公开(公告)号：WO1994026341A1
公开(公告)日：1994-11-24
申请号：PCT/US1994005312
申请日：1994-05-13
申请人： TARGET THERAPEUTICS, INC. , SAMSON, Gene , ENGELSON, Erik, T. , CHEE, Uriel, Hiram , WOODARD, Robert, E.
发明人： TARGET THERAPEUTICS, INC.
IPC分类号： A61M25/00
CPC分类号： A61M25/008 , A61M25/0043 , A61M25/0053 , A61M25/0068 , A61M25/09 , A61M2025/0057 , A61M2025/0073
摘要： The invention is a surgical instrument and specifically is a catheter (100) for treating a target site by delivering a controlled amount of therapeutic or diagnostic agent (the target site being accessible by a tortuous path through the vasculature), the perfusion tip (110) assembly on first catheter, and a process of using that catheter to deliver fluids to the selected vascular site.
摘要翻译：本发明是一种手术器械，特别是用于通过输送受控量的治疗或诊断剂（目标部位可通过脉管系统的曲折路径访问）来治疗靶部位的导管（100），灌注尖端（110）组装在第一导管上，以及使用该导管将流体输送到所选择的血管部位的过程。

14. 发明申请

WO1993016630A1 PROXIMAL END FITTING WITH AN IMPROVED SEAL FOR USE IN A CATHETER GUIDEWIRE ASSEMBLY 审中-公开
标题翻译：带有改进密封件的接头端配件可用于导管指南装配
公开(公告)号：WO1993016630A1
公开(公告)日：1993-09-02
申请号：PCT/US1992011024
申请日：1992-12-16
申请人： TARGET THERAPEUTICS, INC.
发明人： TARGET THERAPEUTICS, INC. , SAMSON, Gene
IPC分类号： A61B05/00
CPC分类号： A61M39/0613
摘要： The invention comprises a proximal end fitting (13) for use within a guidewire assembly wherein the proximal end fitting comprises an elongated radially compressible tube. When in use, the tube is compressed against the O-ring seal (38) in the fitting (13) to better facilitate the seal between the O-ring (38) and the guidewire (11) and thereby better control blood reflux.

15. 发明申请

WO1992013589A1 SINGLE LUMEN LOW PROFILE VALVED BALLOON CATHETER 审中-公开
标题翻译：单灯低剖面阀门气球
公开(公告)号：WO1992013589A1
公开(公告)日：1992-08-20
申请号：PCT/US1992000726
申请日：1992-01-28
申请人： TARGET THERAPEUTICS, INC.
发明人： TARGET THERAPEUTICS, INC. , SAMSON, Gene
IPC分类号： A61M29/00
CPC分类号： A61M29/02 , A61M25/0054 , A61M25/0075 , A61M2025/1063
摘要： A single lumen valved balloon catheter assembly is disclosed that consists of a single lumen catheter tube (18) that has a distally located integral balloon (42) and a built-in guidewire (16) that has a distal valve member (54) that may be moved axially to engage and block the distal end of the catheter. The diameter of the guidewire is reduced at its distal end and the diameter of the lumen of the catheter tube distally of the balloon is reduced to below that of the proximal diameter of the balloon so that the axial movement of the guidewire distally is limited.

16. 发明申请

WO1998017183A1 DETACHABLE MULTIDIAMETER VASOOCCLUSIVE COIL 审中-公开
标题翻译：可拆卸多重血管闭塞线圈
公开(公告)号：WO1998017183A1
公开(公告)日：1998-04-30
申请号：PCT/US1997019517
申请日：1997-10-24
申请人： TARGET THERAPEUTICS, INC. , KEN, Christopher, G., M. , ACHARYA, Abhijit
发明人： TARGET THERAPEUTICS, INC.
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/1214 , A61B2017/1205
摘要： A vasoocclusive helical coil having a proximal end that carries a coupling member for attaching the coil to the distal end of a wire and a proximal winding that has a smaller diameter than adjacent windings whereby the proximal end of the coil is positioned radially inwardly of the main body of the coil.
摘要翻译：一种血管闭塞性螺旋线圈，其具有近端，其具有用于将线圈附接到线的远端的联接构件和具有比相邻绕组更小的直径的近侧绕组，由此线圈的近端位于主体的径向内侧线圈体。

17. 发明申请

WO1996000100A1 MULTILUMEN CATHETER 审中-公开
标题翻译：多层导管
公开(公告)号：WO1996000100A1
公开(公告)日：1996-01-04
申请号：PCT/US1995008017
申请日：1995-06-20
申请人： TARGET THERAPEUTICS, INC. , CHEE, Hiram , GLOWACKI, Mark , SCHALLER, Laurent
发明人： TARGET THERAPEUTICS, INC.
IPC分类号： A61M25/00
CPC分类号： A61M25/0009 , A61M25/0032 , A61M25/0045 , A61M25/0054
摘要： This invention is a surgical device. In particular, it is a multilumen catheter (100) having a shaft (120), at least a portion of which is continuously extruded and undergoes a change in polymer composition during that extension. The invention includes the substituent shaft per se and a method of making the shaft (120).
摘要翻译：本发明是一种手术装置。特别地，它是具有轴（120）的多腔导管（100），其至少一部分被连续地挤出并且在该延伸期间经历聚合物组成的变化。本发明包括取代轴本身以及制造轴（120）的方法。

18. 发明申请

WO1996000035A1 VASOOCCLUSIVE COILS WITH THROMBOGENIC ENHANCING FIBERS 审中-公开
标题翻译：血管增生纤维缠绕线圈
公开(公告)号：WO1996000035A1
公开(公告)日：1996-01-04
申请号：PCT/US1995008075
申请日：1995-06-21
申请人： TARGET THERAPEUTICS, INC. , MIRIGIAN, Gregory, E. , VAN, Nga, Thi
发明人： TARGET THERAPEUTICS, INC.
IPC分类号： A61B17/00
CPC分类号： A61B17/12145 , A61B17/12022 , A61B17/1215
摘要： This invention is a vasoocclusive device (100). It is placed in the vasculature of an animal to form a thrombus in a selected site such as an aneurysm or AVM. The device uses a central coil (102) having thrombogenic fibers (104, 106) placed on the coil in a specified fashion. The coil will pass through the lumen of a vascular catheter and form a convolution when ejected from the catheter's distal end. The fibers are attached to the coil and cooperate with the coil so that upon ejection from the catheter, the convoluted coil forms a shape in which the central region contains the majority of these fibers.
摘要翻译：本发明是一种血管收缩装置（100）。将其置于动物的脉管系统中，以在选定的部位如动脉瘤或AVM中形成血栓。该装置使用具有以特定方式放置在线圈上的血栓形成纤维（104,106）的中心线圈（102）。线圈将穿过血管导管的内腔，并在从导管的远端喷射时形成卷积。纤维连接到线圈并与线圈配合，使得当从导管喷射时，卷积的线圈形成中心区域包含大多数这些纤维的形状。

19. 发明申请

WO1995020417A1 MICROBALLOON CATHETER 审中-公开
公开(公告)号：WO1995020417A1
公开(公告)日：1995-08-03
申请号：PCT/US1995001156
申请日：1995-01-26
申请人： TARGET THERAPEUTICS, INC. , RICHLING, Bernd , SEPETKA, Ivan , CHEE, Uriel, Hiram , HO, Liem , PHAM, Pete, Phong
发明人： TARGET THERAPEUTICS, INC.
IPC分类号： A61M29/00
CPC分类号： A61M25/1006 , A61M25/0054 , A61M25/1025
摘要： This invention is a microballoon (108) tipped catheter (100). The catheter has a shaft (104) which is of varying flexibility with the most flexible portion towards the distal tip. The balloon is of an elastic material. The catheter shaft has a main lumen (114) extending from the proximal end to the distal end so to allow the use of a guidewire (101) in placing the catheter's distal tip in remote regions. The catheter shaft has a wall that desirably is of multilayered construction. The wall preferably includes an independent lumen (110) which may be formed from a small diameter tubing that is placed between layers of the wall, for the inflation and deflation of the microballoon. The inflation lumen proceeds from the proximal end of the catheter and terminates near the distal end of the catheter but within the microballoon.
摘要翻译：本发明是一种微球（108）尖端导管（100）。该导管具有一个轴（104），该轴（104）具有不同的柔性，最靠近顶端的柔性部分。气球是弹性材料。导管轴具有从近端延伸到远端的主腔（114），以允许使用导丝（101）将导管的远端放置在偏远区域中。导管轴具有期望地具有多层结构的壁。壁优选地包括独立的内腔（110），其可以由放置在壁的层之间的小直径管形成，用于微气泡的充气和放气。膨胀腔从导管的近端延伸，并在导管的远端附近终止，但在微球内。

20. 发明申请

WO1994018886A1 FLOW DIRECTED CATHETER 审中-公开
标题翻译：流向导管
公开(公告)号：WO1994018886A1
公开(公告)日：1994-09-01
申请号：PCT/US1994002249
申请日：1994-02-24
申请人： TARGET THERAPEUTICS, INC. , ZENZEN, Wendy, J. , CHEE, Uriel, Hiram
发明人： TARGET THERAPEUTICS, INC.
IPC分类号： A61B06/00
CPC分类号： A61L29/14 , A61L29/041 , A61L29/06 , A61L29/085 , A61L29/16 , A61L2300/00 , A61M25/0009 , A61M25/0045 , A61M25/0054 , A61M25/0125 , A61M2025/0042
摘要： An infusion catheter (100) with an elongate tubular body having proximal and distal ends and a lumen extending between the ends through which a diagnostic, therapeutic, or vaso-occlusive agent can be delivered, is disclosed. The elongate tubular body is formed of a relatively stiff tapered proximal segment (122), a relatively flexible and strong distal segment (120), and a transition section (124) that is less flexible than the distal segment but more flexible than the proximal segment. The infusion catheter is directed to the target site by means of the flow of blood to that site.
摘要翻译：一种具有细长管状体的输注导管（100），其具有近端和远端以及在端部之间延伸的内腔，通过该内腔可以递送诊断性，治疗性或血管闭塞性药剂。细长管状体由相对刚性的渐缩近端段（122），相对柔性和强力的远端段（120）和过渡区段（124）形成，该过渡段（124）比远侧区段柔性小，但比近段更柔性。输液导管通过血液流向该部位而被引导到目标部位。

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