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11. 发明授权

US6150367A 1-[4-arylpiperazin-1-yl]-3-[2-oxopyrrolidin/piperidin-1-yl]propanes and their use in medical treatments 失效
标题翻译： 1- [4-芳基哌嗪-1-基] -3- [2-氧代吡咯烷/哌啶-1-基]丙烷及其在医疗中的应用
公开(公告)号：US6150367A
公开(公告)日：2000-11-21
申请号：US954516
申请日：1997-10-20
申请人： Neelima Sinha , Sanjay Jain , Anil Kumar Saxena , Nitya Anand , Ram Mohan Saxena , Mangal Prasad Dubey , Madhur Ray , Gyanendra K. Patnaik, deceased
发明人： Neelima Sinha , Sanjay Jain , Anil Kumar Saxena , Nitya Anand , Ram Mohan Saxena , Mangal Prasad Dubey , Madhur Ray , Gyanendra K. Patnaik, deceased
IPC分类号： C07D207/26 , C07D207/27 , C07D211/76 , A61K31/496 , C07D401/06 , C07D401/14 , C07D403/06
CPC分类号： C07D207/27 , C07D211/76
摘要： A chemical compound and composition of Formula 1: ##STR1## wherein Ar represents a phenyl ring substituted by the groups like halo, alkoxy, alkyl or heteroaryl, n=1 or n=2; said compounds and compositions as being useful therapeutic agents for hypertension, ischemic, cardiovascular and other adrenergic receptor related disorders.
摘要翻译：式1的化合物和组合物：其中Ar表示被诸如卤素，烷氧基，烷基或杂芳基的基团取代的苯环，n = 1或n = 2; 所述化合物和组合物作为高血压，缺血性，心血管和其它肾上腺素能受体相关疾病的有用治疗剂。

12. 发明授权

US6090809A 1-(4-arylpiperazin-1-yl)-.omega.-[n-(.alpha... omega.-dicarboximido)]-alkanes useful as uro-selective .alpha..sub.1 -adrenoceptor blockers 失效
标题翻译：可用作尿选择性α1-肾上腺素受体阻断剂的1-（4-芳基哌嗪-1-基） - ω-[正（ω-二羧酰亚氨基）] - 烷烃
公开(公告)号：US6090809A
公开(公告)日：2000-07-18
申请号：US203855
申请日：1998-12-02
申请人： Nitya Anand , Neelima Sinha , Sanjay Jain , Anita Mehta , Anil Kumar Saxena
发明人： Nitya Anand , Neelima Sinha , Sanjay Jain , Anita Mehta , Anil Kumar Saxena
IPC分类号： A61K31/496 , C07D207/40 , C07D207/404 , C07D207/408 , C07D211/88 , C07D401/06 , C07D403/06
CPC分类号： C07D207/404 , A61K31/496 , C07D207/408 , C07D211/88 , C07D401/06
摘要： Novel piperzine derivatives substituted on one nitrogen by an aromatic system and on the other nitrogen by (2,5-dioxopyrrolidin)-1-yl) alkanes or (2,6-dioxopiperidin-1-yl) alkanes have been found to exhibit selective .alpha..sub.1A adrenergic activity. The compounds are useful for treatment of disease conditions, such as peripheral vascular disease, congestive heart failure, hypertension and especially benign prostatic hypertrophy.
摘要翻译：已经发现通过芳族体系在一个氮上取代的新颖的哌嗪衍生物，在另一个氮上被（2,5-二氧代吡咯烷-1-基）烷烃或（2,6-二氧代哌啶-1-基）烷烃取代，表现出选择性的α 1A肾上腺素能活动。该化合物可用于治疗疾病状况，如外周血管疾病，充血性心力衰竭，高血压，特别是良性前列腺肥大。

13. 发明授权

US6084097A Methods for preparing 1-[4-arylpiperazin-1-yl]-3-[2-oxopyrrolidin/piperidin-1-yl] propanes 失效
标题翻译： 1- [4-芳基哌嗪-1-基] -3- [2-氧代吡咯烷/哌啶-1-基]丙烷的制备方法
公开(公告)号：US6084097A
公开(公告)日：2000-07-04
申请号：US960335
申请日：1997-10-29
申请人： Neelima Sinha , Sanjay Jain , Anil Kumar Saxena , Nitya Anand , Ram Mohan Saxena , Mangal Prasad Dubey , Madhur Ray , Gyanendra Kumar Patnaik, deceased
发明人： Neelima Sinha , Sanjay Jain , Anil Kumar Saxena , Nitya Anand , Ram Mohan Saxena , Mangal Prasad Dubey , Madhur Ray , Gyanendra Kumar Patnaik, deceased
IPC分类号： C07D207/26 , C07D207/27 , C07D211/76 , C07D401/06 , C07D401/14 , C07D403/06
CPC分类号： C07D211/76 , C07D207/27
摘要： The invention relates to a process for the synthesis of 1-[4-Arylpiperazin-1-yl]-3-[2-oxopyrrolidin/piperidin-1-yl]propanes used as potential therapeutic agents for hypertension, ischemia, cardiovascular and other adrenergic receptors related disorders, having general formula 1 ##STR1## wherein Ar represents a phenyl ring substituted by the groups like halo, alkoxy, alkyl or heteroaryl, n=1 or n=2; a process of preparing said compounds and a method of treating hypertension, ischemia, cardiovascular and other adrenergic receptors related disorders.
摘要翻译：本发明涉及用作高血压，缺血，心血管和其他肾上腺素能潜在治疗剂的1- [4-芳基哌嗪-1-基] -3- [2-氧代吡咯烷/哌啶-1-基]丙烷的合成方法受体相关疾病，具有通式1，其中Ar表示被诸如卤素，烷氧基，烷基或杂芳基的基团取代的苯环，n = 1或n = 2; 制备所述化合物的方法和治疗高血压，缺血，心血管和其它肾上腺素能受体相关疾病的方法。

14. 发明授权

US6083950A 1-(4-arylpiperazin-1-yl)-.omega.-[n-(.alpha.,.omega.-dicarboximido)]-alka nes useful as uro-selective .alpha.1-adrenoceptor blockers 失效
标题翻译：可用作尿选择性α1-肾上腺素受体阻断剂的1-（4-芳基哌嗪-1-基） - ω-[n-（α，ω-二氨基）] - 烷烃
公开(公告)号：US6083950A
公开(公告)日：2000-07-04
申请号：US120265
申请日：1998-07-21
申请人： Nitya Anand , Neelima Sinha , Sanjay Jain , Anita Mehta , Jang Bahadurgupta
发明人： Nitya Anand , Neelima Sinha , Sanjay Jain , Anita Mehta , Jang Bahadurgupta
IPC分类号： A61K31/496 , C07D207/40 , C07D207/404 , C07D207/408 , C07D211/88 , C07D401/06 , A61K31/495
CPC分类号： C07D207/404 , A61K31/496 , C07D207/408 , C07D211/88 , C07D401/06
摘要： Novel piperzine derivatives substituted on one nitrogen by an aromatic system and on the other nitrogen by (2,5-dioxopyrrolidin)-1-yl) alkanes or (2,6-dioxopiperidin-1-yl) alkanes have been found to exhibit selective .alpha..sub.1A adrenergic activity. The compounds are useful for treatment of disease conditions, such as peripheral vascular disease, congestive heart failure, hypertension and especially benign prostatic hypertrophy.
摘要翻译：已经发现通过芳族体系在一个氮上取代的新颖的哌嗪衍生物，在另一个氮上被（2,5-二氧代吡咯烷-1-基）烷烃或（2,6-二氧代哌啶-1-基）烷烃取代，表现出选择性的α 1A肾上腺素能活动。该化合物可用于治疗疾病状况，例如外周血管疾病，充血性心力衰竭，高血压，特别是良性前列腺肥大。

15. 发明申请

US20110159130A1 REDUCTION OF ENDOTOXIN IN POLYSIALIC ACIDS 审中-公开
标题翻译：减少多糖中的内毒素
公开(公告)号：US20110159130A1
公开(公告)日：2011-06-30
申请号：US12528763
申请日：2008-02-28
申请人： Sanjay Jain , Peter Laing , Gregory Gregoriadis
发明人： Sanjay Jain , Peter Laing , Gregory Gregoriadis
IPC分类号： A61K35/74 , C07K14/00 , C12P21/06
CPC分类号： C08B37/0006 , B01D15/363 , C08B37/0003
摘要： The present invention relates to process for reducing the endotoxin content of a sample of fermentation broth containing polysialic acid and endotoxin comprising the sequential steps: (i) adding to the sample a base having a pKa of at least 12 to form a basic solution having a pH of at least 12, incubating the solution for a pre-determined time at a pre-determined temperature; and (ii) recovery of PSA, suitably by (iii) passing the sample through an anion-exchange column whereby polysialic acid is absorbed on the ion exchange resin; (iv) washing the column with one washing buffer, whereby polysialic acid remains absorbed on the ion exchange resin; and (v) eluting the polysialic acid from the column using an elution buffer to provide a product solution of polysialic acid having reduced endotoxin content.
摘要翻译：本发明涉及降低含有唾液酸和内毒素的发酵肉汤样品的内毒素含量的方法，其包括以下顺序步骤：（i）向样品中加入pKa至少为12的碱，以形成具有 pH至少为12，在预定温度下将溶液温育预定时间; 和（ii）PSA的回收，适当地通过（iii）使样品通过阴离子交换柱，由此唾液酸被吸收在离子交换树脂上; （iv）用一个洗涤缓冲液洗涤该柱，由此聚唾液酸保持吸收在离子交换树脂上; 和（v）使用洗脱缓冲液从柱洗脱聚唾液酸以提供具有降低的内毒素含量的聚唾液酸的产物溶液。

16. 发明授权

US07652988B2 Hardware-based rate control for bursty traffic 有权
标题翻译：突发性流量的基于硬件的速率控制
公开(公告)号：US07652988B2
公开(公告)日：2010-01-26
申请号：US10446419
申请日：2003-05-28
申请人： Sanjay Jain , Deepak Aatresh , Daniel M. Hegglin
发明人： Sanjay Jain , Deepak Aatresh , Daniel M. Hegglin
IPC分类号： H04L12/26
CPC分类号： H04L47/10
摘要： A hardware-based rate control engine is designed to allow credits to be accumulated over multiple time-slices up to a maximum credit limit. The rate control engine is also allowed to dispatch packets up to a maximum drain rate during each time-slice as long as sufficient credits are available. Allowing credits to accumulate over multiple time slices allows unused bandwidth to be saved during times of little or no traffic and used when the subsequent traffic bursts arrive. Additionally, limiting the maximum drain rate puts a cap on how fast the saved bandwidth can be consumed by subsequent traffic bursts. The rate control settings can be adapted in response to a characteristic, or characteristics, of the traffic flow. For example, one group of settings of a traffic flow can be used for bursty traffic, while a different group of settings can be used for smooth traffic.
摘要翻译：基于硬件的速率控制引擎被设计为允许在多个时间片上积累信用以达到最大信用限额。只要有足够的信用额度，速率控制引擎也可以在每个时间片段内调度数据包，达到最大排放速率。允许信用累积多个时间片允许在很少或没有流量的时间内保存未使用的带宽，并且在随后的业务突发到达时使用。另外，限制最大漏极率可以说明随后的业务脉冲串可以节省多长时间的带宽。速率控制设置可以响应于业务流的特性或特性进行调整。例如，流量的一组设置可以用于突发流量，而不同的设置组可用于平滑流量。

17. 发明申请

US20070179980A1 Methods and apparatus to manage shadow copy providers 有权
标题翻译：管理影子拷贝提供者的方法和设备
公开(公告)号：US20070179980A1
公开(公告)日：2007-08-02
申请号：US11343012
申请日：2006-01-30
申请人： Wei Liu , Sanjay Jain
发明人： Wei Liu , Sanjay Jain
IPC分类号： G06F17/30
CPC分类号： G06F17/30067
摘要： A data storage management system includes a virtual provider for interacting with a coordinator to receive shadow copy requests from a requestor and for interfacing with a plurality of providers that support various logical units on which data volumes can be stored. The virtual provider appears to the coordinator as a provider and can generate a shadow copy of a first one of the data volumes that spans multiple ones of the logical units, which are supported by different ones of the plurality of providers.
摘要翻译：数据存储管理系统包括用于与协调器进行交互以接收来自请求者的卷影复制请求的虚拟提供者，以及用于与支持能够存储数据卷的各种逻辑单元的多个提供者进行接口。虚拟提供商作为提供者向协调器显示，并且可以生成跨越多个逻辑单元的第一个数据卷的第一个卷影副本，这些多个逻辑单元由多个提供者中的不同的提供者支持。

18. 发明申请

US20050240561A1 Monitoring and controlling work progress 审中-公开
标题翻译：监测和控制工作进展
公开(公告)号：US20050240561A1
公开(公告)日：2005-10-27
申请号：US11113565
申请日：2005-04-25
申请人： Sanjay Jain , Anthony Amato
发明人： Sanjay Jain , Anthony Amato
IPC分类号： G06F7/00 , G06Q10/00
CPC分类号： G06Q10/06
摘要： The invention relates to products for, and methods of, monitoring and controlling work progress, and improving work productivity and work management, for example in highly variable and/or unpredictable work environments, and to products for, and methods of, interactive data processing particularly adapted for systems comprising a handheld mobile component
摘要翻译：本发明涉及例如在高度可变和/或不可预测的工作环境中的工作进展的产品和监测和控制方法，以及提高工作效率和工作管理，以及交互式数据处理的产品和方法，特别是适用于包括手持移动组件的系统

19. 发明申请

US20050238012A1 Programmable packet parsing processor 有权
公开(公告)号：US20050238012A1
公开(公告)日：2005-10-27
申请号：US10927290
申请日：2004-08-25
申请人： Rina Panigrahy , Jackie Liu , Daniel Ng , Sanjay Jain , Nagaraj Bagepalli , Abhijit Patra
发明人： Rina Panigrahy , Jackie Liu , Daniel Ng , Sanjay Jain , Nagaraj Bagepalli , Abhijit Patra
IPC分类号： H04L12/56 , H04L29/06
CPC分类号： H04L63/0254 , H04L63/1408 , H04L69/22
摘要： The present invention provides a packet processing device and method. A parsing processor provides instruction-driven content inspection of network packets at 10-Gbps and above with a parsing engine that executes parsing instructions. A flow state unit maintains statefulness of packet flows to allow content inspection across several related network packets. A state-graph unit traces state-graph nodes to keyword indications and/or parsing instructions. The parsing instructions can be derived from a high-level application to emulate user-friendly parsing logic. The parsing processor sends parsed packets to a network processor unit for further processing.

20. 发明授权

US5586332A Power management for low power processors through the use of auto clock-throttling 失效
标题翻译：通过使用自动时钟调节功能管理低功耗处理器
公开(公告)号：US5586332A
公开(公告)日：1996-12-17
申请号：US036343
申请日：1993-03-24
申请人： Sanjay Jain , Deepak J. Aatresh
发明人： Sanjay Jain , Deepak J. Aatresh
IPC分类号： G06F1/32
CPC分类号： G06F9/3885 , G06F1/3203 , G06F1/3237 , G06F1/3287 , G06F9/30083 , G06F9/3869 , Y02B60/1221 , Y02B60/1282 , Y02B60/32
摘要： A clock throttling mechanism turns off certain processor components to minimize power consumption. The processor detects the issuance of certain bus cycles or the execution of certain instructions which typically cause the processor to be idle for a period of time. Control circuitry detects the existence of the instruction and/or bus cycle and shuts down the clock driving certain processor components during that idle period. The control circuitry then detects the occurrence or upcoming occurrence of an event to which the processor responds and becomes active. At detection of this event, the clock signal input to these components is then restarted such that the processor can continue normal execution.
摘要翻译：时钟调节机制关闭某些处理器组件以最小化功耗。处理器检测某些总线周期的发布或某些指令的执行，这些指令通常会导致处理器空闲一段时间。控制电路检测指令和/或总线周期的存在，并在该空闲期间关闭驱动某些处理器组件的时钟。然后，控制电路检测处理器响应并发生事件的发生或即将发生。在检测到该事件时，输入到这些组件的时钟信号然后重新启动，使得处理器可以继续正常执行。

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