专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明申请

US20080139564A1 SUBSTITUTED PHENYL PROPYL AMINES AS HISTAMINE H3 RECEPTOR AND SEROTONIN TRANSPORTER MODULATORS 审中-公开
标题翻译：作为组胺H3受体和丝氨酸转运蛋白调节剂的取代苯基丙氨酰胺
公开(公告)号：US20080139564A1
公开(公告)日：2008-06-12
申请号：US11939881
申请日：2007-11-14
申请人： John M. Keith , Jennifer M.B. Miller , Emily M. Stocking
发明人： John M. Keith , Jennifer M.B. Miller , Emily M. Stocking
IPC分类号： A61K31/5375 , A61P25/28 , C07D211/06 , A61K31/445 , C07D295/027 , A61K31/496
CPC分类号： C07D295/135 , C07D213/65
摘要： Certain substituted phenyl propyl amine compounds are histamine H3 receptor and/or serotonin transporter modulators useful in the treatment of histamine H3 receptor- and/or serotonin-mediated diseases.
摘要翻译：某些取代的苯基丙基胺化合物是可用于治疗组胺H 3受体和/或5-羟色胺介导的疾病的组胺H 3 N 3受体和/或5-羟色胺转运体调节剂。

12. 发明授权

US4835607A Method and apparatus for expanding compressed video data 失效
标题翻译：用于扩展压缩视频数据的方法和装置
公开(公告)号：US4835607A
公开(公告)日：1989-05-30
申请号：US121818
申请日：1987-11-16
申请人： John M. Keith
发明人： John M. Keith
IPC分类号： H04N7/26 , H04N7/36 , H04N7/46
CPC分类号： H04N19/00 , H04N19/503 , H04N19/587 , H04N19/59
摘要： A processor which expands a compressed video signal is disclosed. The compressed video signal applied to the processor is generated by partitioning a video image into segments and then describing how each segment is filled by using a bilinear equation, that is to say, a linear equation which is a function of a horizontal coordinate X and a vertical coordinate Y. The coefficients of the X and Y coordinates each include integer and fractional parts. The circuitry develops a table of values from the coefficient of the X coordinate by repeatedly adding the coefficient in an accumulator. As each sum is produced, the integer part of the sum is stored. The table of values is developed from the stored integer sums as the difference between alternate sums, where successive alternate pairs of sums are interleaved. For example, the table would include the difference between the first and third sums followed by the difference between the second and fourth sums, then the third and fifth sums and so on. The segment is reconstructed by accumulating alternate ones of the table entries in separate adders. At each stage in the accumulation, the output values of the two adders are two successive pixel values along the horizontal coordinate of the segment.
摘要翻译：公开了一种扩展压缩视频信号的处理器。通过将视频图像分割成段，然后通过使用双线性方程（即，作为水平坐标X和A的函数的线性方程）描述如何填充每个段来生成施加到处理器的压缩视频信号垂直坐标Y.X和Y坐标的系数各包括整数和小数部分。该电路通过在累加器中反复添加系数，从X坐标的系数开始产生一个值表。当产生每个和时，存储和的整数部分。值表是从存储的整数和作为交替和之间的差异开发的，其中相加的交替对的并行交错。例如，该表将包括第一和第三和之后的差值，之后是第二和第四和之差，然后是第三和第五和等等。通过在单独的加法器中累加替代的表条目来重构段。在积累的每个阶段，两个加法器的输出值是沿着该段的水平坐标的两个连续的像素值。

13. 发明授权

US08273762B2 Hexahydro-pyrrolo-isoquinoline compounds 有权
标题翻译：六氢吡咯异喹啉化合物
公开(公告)号：US08273762B2
公开(公告)日：2012-09-25
申请号：US12792675
申请日：2010-06-02
申请人： Richard Apodaca , Ann J. Barbier , Nicholas I. Carruthers , Leslie A. Gomez , John M. Keith , Timothy W. Lovenberg , Ronald L. Wolin
发明人： Richard Apodaca , Ann J. Barbier , Nicholas I. Carruthers , Leslie A. Gomez , John M. Keith , Timothy W. Lovenberg , Ronald L. Wolin
IPC分类号： C07D487/02 , A61K31/4353
CPC分类号： C07D471/04
摘要： Certain hexahydro-pyrrolo-isoquinoline compounds are histamine H3 receptor and serotonin transporter modulators useful in the treatment of histamine H3 receptor- and serotonin-mediated diseases.
摘要翻译：某些六氢 - 吡咯并 - 异喹啉化合物是可用于治疗组胺H3受体和5-羟色胺介导的疾病的组胺H3受体和5-羟色胺转运体调节剂。

14. 发明申请

US20090137562A1 SUBSTITUTED BENZYL AMINE COMPOUNDS 审中-公开
标题翻译：取代苄基化合物
公开(公告)号：US20090137562A1
公开(公告)日：2009-05-28
申请号：US12330574
申请日：2008-12-09
申请人： Brett Allison , Michael P. Curtis , Cheryl A. Grice , John M. Keith , Michael A. Letavic , Jennifer M.B. Miller , Emily M. Stocking
发明人： Brett Allison , Michael P. Curtis , Cheryl A. Grice , John M. Keith , Michael A. Letavic , Jennifer M.B. Miller , Emily M. Stocking
IPC分类号： A61K31/551 , C07D241/04 , A61K31/495 , A61K31/5377 , A61P25/28 , C07D413/04 , C07D243/08
CPC分类号： C07C237/34 , C07D209/08 , C07D209/40 , C07D213/65 , C07D213/70 , C07D213/74 , C07D241/08 , C07D243/24 , C07D295/13 , C07D295/135 , C07D295/192 , C07D401/10 , C07D401/12 , C07D413/04
摘要： Certain substituted benzyl amine compounds are histamine H3 receptor and/or serotonin transporter modulators useful in the treatment of histamine H3 receptor- and/or serotonin-mediated diseases.
摘要翻译：某些取代的苄胺化合物是可用于治疗组胺H3受体和/或血清素介导的疾病的组胺H3受体和/或血清素转运体调节剂。

15. 发明申请

US20080004258A1 BUTYL AND BUTYNYL BENZYL AMINE COMPOUNDS 有权
标题翻译：丁基和丁基苄基化合物
公开(公告)号：US20080004258A1
公开(公告)日：2008-01-03
申请号：US11766151
申请日：2007-06-21
申请人： John M. Keith , Michael A. Letavic , Emily M. Stocking
发明人： John M. Keith , Michael A. Letavic , Emily M. Stocking
IPC分类号： A61K31/551 , A61K31/135 , A61K31/445 , A61K31/495 , A61P21/00 , A61P29/00 , C07C211/00 , C07D243/06 , C07D295/00 , C07D221/00 , A61P3/00 , A61P25/00 , A61P15/00 , A61K31/5375 , A61K31/54
CPC分类号： C07C323/21 , C07C217/58 , C07C323/20 , C07C2601/02 , C07D211/38 , C07D213/64 , C07D213/65 , C07D213/70 , C07D241/08 , C07D243/08 , C07D295/08 , C07D295/096 , C07D295/135
摘要： Certain substituted butyl and butynyl benzyl amine compounds are histamine H3 receptor and/or serotonin transporter modulators useful in the treatment of histamine H3 receptor- and/or serotonin-mediated diseases.
摘要翻译：某些取代的丁基和丁炔基苄胺化合物是可用于治疗组胺H 3受体和/或5-羟色胺介导的疾病的组胺H 3 N 3受体和/或5-羟色胺转运蛋白调节剂。

16. 发明授权

US08637520B2 Substituted pyridyl amide compounds as modulators of the histamine H3 receptor 有权
标题翻译：取代的吡啶酰胺化合物作为组胺H3受体的调节剂
公开(公告)号：US08637520B2
公开(公告)日：2014-01-28
申请号：US12828883
申请日：2010-07-01
申请人： John M. Keith , Michael A. Letavic , Kiev S. Ly , Neelakandha S. Mani , John E. Mills , Chennagiri R. Pandit , Frank J. Villani , Hua Zhong
发明人： John M. Keith , Michael A. Letavic , Kiev S. Ly , Neelakandha S. Mani , John E. Mills , Chennagiri R. Pandit , Frank J. Villani , Hua Zhong
IPC分类号： A61K31/496 , C07D401/06
CPC分类号： C07D213/82 , C07D213/81 , C07D213/84 , C07D401/06
摘要： Certain substituted pyridyl amide compounds are histamine H3 receptor modulators useful in the treatment of histamine H3 receptor-mediated diseases.
摘要翻译：某些取代的吡啶酰胺化合物是可用于治疗组胺H3受体介导的疾病的组胺H3受体调节剂。

17. 发明授权

US08461159B2 Heteroaryl-substituted urea modulators of fatty acid amide hydrolase 有权
标题翻译：脂肪酰胺水解酶的杂芳基取代的脲调节剂
公开(公告)号：US08461159B2
公开(公告)日：2013-06-11
申请号：US13131067
申请日：2009-11-24
申请人： J. Guy Breitenbucher , John M. Keith , Mark S. Tichenor , Alison L. Chambers , William M. Jones , Natalie A. Hawryluk , Amy K. Timmons , Jeffrey E. Merit , Mark J. Seierstad
发明人： J. Guy Breitenbucher , John M. Keith , Mark S. Tichenor , Alison L. Chambers , William M. Jones , Natalie A. Hawryluk , Amy K. Timmons , Jeffrey E. Merit , Mark J. Seierstad
IPC分类号： A61K31/495 , C07D419/00
CPC分类号： C07D498/04 , C07D231/56 , C07D295/195 , C07D403/12 , C07D413/12 , C07D413/14 , C07D471/04 , C07D471/12 , C07D487/04
摘要： Certain heteroaryl-substituted piperidinyl and piperazinyl urea compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity, such as anxiety, pain, inflammation, sleep disorders, eating disorders, insulin resistance, diabetes, osteoporosis, and movement disorders (e.g., multiple sclerosis).
摘要翻译：描述了某些杂芳基取代的哌啶基和哌嗪基脲化合物，其可用作FAAH抑制剂。这些化合物可用于治疗由脂肪酸酰胺水解酶（FAAH）活性介导的疾病状态，病症和病症的药物组合物和方法，例如焦虑症，疼痛，炎症，睡眠障碍，进食障碍，胰岛素抵抗，糖尿病，骨质疏松症和运动障碍（例如，多发性硬化症）。

18. 发明申请

US20120149696A1 ETHYLENE DIAMINE MODULATORS OF FATTY ACID HYDROLASE 有权
标题翻译：脂肪酸水解酶的乙烯二胺调节剂
公开(公告)号：US20120149696A1
公开(公告)日：2012-06-14
申请号：US13390984
申请日：2010-08-17
申请人： Natalie A. Hawryluk , J. Guy Breitenbucher , William M. Jones , Alison L. Chambers , John M. Keith , Mark Selerstad
发明人： Natalie A. Hawryluk , J. Guy Breitenbucher , William M. Jones , Alison L. Chambers , John M. Keith , Mark Selerstad
IPC分类号： A61K31/505 , C07D409/04 , C07D417/12 , A61K31/506 , A61P25/22 , A61P25/24 , A61P25/00 , A61P3/04 , A61P29/00 , A61P25/14 , A61P25/28 , A61P25/08 , A61P25/16 , A61P27/02 , A61P25/30 , A61P1/08 , A61P15/00 , A61P27/06 , A61P1/00 , A61P37/06 , A61P1/04 , A61P1/12 , A61P15/04 , A61P9/12 , A61P35/00 , A61P31/14 , A61P37/08 , A61P37/00 , A61P17/04 , A61P3/10 , A61P3/00 , A61P19/10 , A61P19/00 , C07D239/42
CPC分类号： C07D239/42 , C07D401/04 , C07D403/12 , C07D405/04 , C07D405/12 , C07D409/04 , C07D409/12 , C07D413/04 , C07D413/12 , C07D417/12
摘要： Certain ethylene diamine compounds of Formula (I) are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity, such as anxiety, pain, inflammation, sleep disorders, eating disorders, energy metabolism disorders, and movement disorders (e.g., multiple sclerosis). Methods of synthesizing such compounds are also disclosed.
摘要翻译：描述了某些式（I）的乙二胺化合物，其可用作FAAH抑制剂。这些化合物可用于治疗由脂肪酰胺水解酶（FAAH）活性介导的疾病状态，病症和病症的药物组合物和方法，例如焦虑症，疼痛，炎症，睡眠障碍，进食障碍，能量代谢紊乱，和运动障碍（例如多发性硬化）。还公开了合成这些化合物的方法。

19. 发明申请

US20120088741A1 ARYL-SUBSTITUTED HETEROCYCLIC UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE 有权
标题翻译：脂肪酸酰胺水解酶的ARYL取代的杂环尿素调节剂
公开(公告)号：US20120088741A1
公开(公告)日：2012-04-12
申请号：US13375855
申请日：2010-06-04
申请人： J. Guy Breitenbucher , Mark S. Tichenor , Jeffrey E. Merit , John M. Keith , Natallie A. Hawryluk , Alison L. Chambers
发明人： J. Guy Breitenbucher , Mark S. Tichenor , Jeffrey E. Merit , John M. Keith , Natallie A. Hawryluk , Alison L. Chambers
IPC分类号： A61K31/616 , C07D401/12 , C07D405/14 , C07D401/14 , C07D471/04 , A61K31/5025 , A61K31/4427 , A61K31/443 , A61K31/4709 , A61K31/4725 , A61K31/4439 , A61K31/437 , C12N9/99 , A61P25/04 , A61P29/00 , A61P25/22 , A61P25/24 , A61P25/00 , A61P25/14 , A61P25/28 , A61P25/08 , A61P25/16 , A61P1/08 , A61P15/00 , A61P27/06 , A61P1/00 , A61P1/04 , A61P1/12 , A61P19/02 , A61P9/12 , A61P35/00 , A61P3/10 , A61P17/04 , A61P19/10 , A61P3/00 , C07D487/04
CPC分类号： C07D487/04 , C07D401/12 , C07D401/14 , C07D413/12 , C07D471/04
摘要： Certain aryl-substituted heterocyclic urea compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity, such as anxiety, pain, inflammation, sleep disorders, eating disorders, energy metabolism disorders, and movement disorders (e.g., multiple sclerosis).
摘要翻译：描述了某些芳基取代的杂环脲化合物，其可用作FAAH抑制剂。这些化合物可用于治疗由脂肪酰胺水解酶（FAAH）活性介导的疾病状态，病症和病症的药物组合物和方法，例如焦虑症，疼痛，炎症，睡眠障碍，进食障碍，能量代谢紊乱，和运动障碍（例如多发性硬化）。

20. 发明授权

US07846930B2 Diaryl-substituted tetrahydroisoquinolines as histamine H3 receptor and serotonin transporter modulators 有权
标题翻译：二芳基取代的四氢异喹啉作为组胺H3受体和血清素转运体调节剂
公开(公告)号：US07846930B2
公开(公告)日：2010-12-07
申请号：US12119811
申请日：2008-05-13
申请人： John M. Keith
发明人： John M. Keith
IPC分类号： A61K31/5377 , A61K31/4725 , C07D217/14 , C07D413/14 , C07D413/12
CPC分类号： C07D217/14 , C07D401/12 , C07D401/14 , C07D417/12
摘要： Certain diaryl-substituted tetrahydroisoquinoline compounds are histamine H3 receptor and/or serotonin transporter modulators useful in the treatment of histamine H3 receptor- and/or serotonin-mediated diseases.
摘要翻译：某些二芳基取代的四氢异喹啉化合物是可用于治疗组胺H3受体和/或血清素介导的疾病的组胺H3受体和/或血清素转运蛋白调节剂。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式