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11. 发明授权

US06900943B2 Optical amplification in coherent optical frequency modulated continuous wave reflectometry 失效
标题翻译：相干光调制连续波反射测量中的光放大
公开(公告)号：US06900943B2
公开(公告)日：2005-05-31
申请号：US10399511
申请日：2001-10-31
申请人： Peter E. Andersen , Anders Bjarklev , Andrea Tycho
发明人： Peter E. Andersen , Anders Bjarklev , Andrea Tycho
IPC分类号： A61B5/00 , G01B9/02 , G01M11/00 , G01N21/47 , G02B27/10 , H01S3/10
CPC分类号： G01N21/4795 , A61B5/0059 , A61B5/0066 , G01B9/02004 , G01B9/02091 , G01M11/3127 , G01M11/3172
摘要： The present invention relates to an apparatus for optical coherence reflectometry, in particular for optical coherence tomography, wherein the apparatus for optical coherence reflectometry comprises a wavelength scanning laser source for providing a light signal, and splitting means for dividing said light signal into a sample light field and a reference light field, wherein the sample light field is directed to the sample being measured, and the light reflected from the sample is amplified without correspondingly amplifying the light reflected in the reference light field. Thereby, it is possible to direct substantially all light energy from the first reflected light field to the detectors, and to obtain fully the utilization of the amplification of the first reflected light field. The optica amplifier inserted in the sample reflected light field is different from the source so that the effect of the light source may be regulated independent of the degree of amplification. In particular when using the apparatus in coherent optical FMCW reflectometry certain safety regulations for the power density towards the sample has to be observed to reduce the risk of damages to the sample under examination, such as biological tissue. The apparatus may be used for a variety of purposes, in particular for obtaining optical biopsies of transparent as well as non-transparent tissues.
摘要翻译：本发明涉及一种用于光学相干反射测量的装置，特别是用于光学相干断层摄影，其中用于光学相干反射测量的装置包括用于提供光信号的波长扫描激光源，以及用于将所述光信号分成采样光的分离装置场和参考光场，其中样本光场被引导到正被测量的样本，并且从样本反射的光被放大，而不会相应地放大在参考光场中反射的光。由此，可以将来自第一反射光场的基本上所有的光能量引导到检测器，并且完全获得对第一反射光场的放大的利用。插入在样本反射光场中的光学放大器不同于源，使得可以独立于放大程度来调节光源的影响。特别是当在相干光学FMCW反射测量中使用该设备时，必须遵守某些针对样品的功率密度的安全规定，以降低对检测样品（如生物组织）的损害风险。该装置可以用于各种目的，特别是用于获得透明和非透明组织的光学活组织检查。

12. 发明授权

US06853457B2 Optical amplification in coherence reflectometry 失效
标题翻译：相干反射光学放大
公开(公告)号：US06853457B2
公开(公告)日：2005-02-08
申请号：US10363323
申请日：2001-09-04
申请人： Anders Bjarklev , Andreas Tycho , Peter E. Andersen
发明人： Anders Bjarklev , Andreas Tycho , Peter E. Andersen
IPC分类号： A61B5/00 , G01B9/02 , G01N21/47
CPC分类号： G01N21/4795 , A61B5/0066 , A61B5/0086 , G01B9/02091
摘要： The present invention relates to an apparatus and a method for optical coherence reflectometry, in particular for optical coherence tomography. The invention particularly relates to the route of the light field in the sample arm. The reflected light field in the sample arm is amplified before being received by a combining means, said combining means being capable of receiving the reflected light field from the sample arm as well as the second reflected light field from the reference arm. Thereby, it is possible to direct substantially all light energy in the sample arm to the combining means, and to obtain fully the utilisation of the amplification of the reflected light field since preferably only the reflected light field is amplified by the optical amplifier. This leads to an improved signal-to-noise ratio (SNR) whereby an increase of the maximal penetration depth is obtained. Thereby, the apparatus is useful for obtaining optical biopsies of transparent as well as non-transparent tissues as well as new technical fields wherein the increased SNR allows the use of the present apparatus.
摘要翻译：本发明涉及一种用于光学相干反射测量的装置和方法，特别是用于光学相干层析成像。本发明特别涉及样品臂中的光场的路线。采样臂中的反射光场在被组合装置接收之前被放大，所述组合装置能够接收来自采样臂的反射光场以及来自参考臂的第二反射光场。因此，可以将采样臂中的基本上所有的光能引导到组合装置，并且完全可以利用反射光场的放大，因为优选地只有反射光场被光放大器放大。这导致改善的信噪比（SNR），从而获得最大穿透深度的增加。因此，该装置对于获得透明和非透明组织的光学活组织检查以及新的技术领域是有用的，其中增加的SNR允许使用本装置。

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