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11. 发明授权

US08202732B2 Method for analyzing activated polyethylene glycol compounds 失效
标题翻译：分析活性聚乙二醇化合物的方法
公开(公告)号：US08202732B2
公开(公告)日：2012-06-19
申请号：US13280790
申请日：2011-10-25
申请人： Ross A Wallingford , Maciej Turowski
发明人： Ross A Wallingford , Maciej Turowski
IPC分类号： G01N33/00
CPC分类号： G01N30/88 , A61K47/60 , G01N2030/8813 , G01N2030/8854 , Y10T436/200833 , Y10T436/2575
摘要： A chemical analysis method for the determination of RO(CH2CH2O)nH, RO(C2H4O)nA, and AO(C2H4O)nA in a mixture thereof, wherein R is an alkyl group, A is a functional group for coupling with a surface or a biologically active material or another thing of use and n is an integer greater than 10. The method includes derivatizing the A groups of the mixture with a derivatizing agent to form a derivatized mixture comprising RO(CH2CH2O)nH, RO(C2H4O)nAD, and DAO(C2H4O)nAD, wherein AD is the derivatized A group. The second step is chromatographing a sample of the derivatized mixture by liquid chromatography under critical conditions to determine the relative amounts of RO(CH2CH2O)nH, RO(C2H4O)nAD, and DAO(C2H4O)nAD in the derivatized mixture.
摘要翻译：用于在其混合物中测定RO（CH 2 CH 2 O）n H，RO（C 2 H 4 O）n A和AO（C 2 H 4 O）n A）的化学分析方法，其中R是烷基，A是与表面偶联的官能团生物活性物质或另一种使用的物质，n是大于10的整数。该方法包括用衍生剂衍生化A组的混合物，以形成衍生的混合物，其包含RO（CH 2 CH 2 O）nH，RO（C 2 H 4 O）n AD和 DAO（C2H4O）nAD，其中AD是衍生的A组。第二步是在临界条件下通过液相色谱法对衍生化混合物的样品进行色谱分析，以确定衍生化混合物中RO（CH2CH2O）nH，RO（C2H4O）nAD和DAO（C2H4O）nAD的相对量。

12. 发明申请

US20100331278A1 USES OF CATIONIC HYDROXYETHYLCELLULOSE IN ORAL INGESTION FORMS, AND PREVENTION AND TREATMENT OF METABOLIC DISORDERS 审中-公开
标题翻译：口服羟丙基纤维素在口腔吸收形式中的应用及预防和治疗代谢障碍
公开(公告)号：US20100331278A1
公开(公告)日：2010-12-30
申请号：US12775180
申请日：2010-05-06
申请人： W. H. Kerr Anderson , Shao-Ching Hung , William T. Stott , Maciej Turowski , Wallace H. Yokoyama , Scott A. Young
发明人： W. H. Kerr Anderson , Shao-Ching Hung , William T. Stott , Maciej Turowski , Wallace H. Yokoyama , Scott A. Young
IPC分类号： A61K31/717 , C08B11/08 , A61P3/04 , A61P3/00 , A61P3/06 , A61P3/10
CPC分类号： A61K31/717 , A23L2/52 , A23L33/24 , A23V2002/00 , A23V2200/326 , A23V2200/332 , A23V2200/322 , A23V2250/5108
摘要： Described are an oral ingestion form comprising cationic hydroxyethylcellulose, and methods of using the same in prevention and treatment of metabolic disorders.
摘要翻译：描述了包含阳离子羟乙基纤维素的口服摄取形式，及其用于预防和治疗代谢紊乱的方法。

13. 发明申请

US20100112122A1 METHOD OF PREFERENTIALLY REDUCING ABSORBABILITY OF SATURATED FATTY ACIDS 审中-公开
标题翻译：优选降低饱和脂肪酸的吸收性的方法
公开(公告)号：US20100112122A1
公开(公告)日：2010-05-06
申请号：US12112775
申请日：2008-04-30
申请人： Yun-Jeong Hong , Scott A. Young , Maciej Turowski , Wallace H. Yokoyama , Marsha L. Langhorst , David R. Albers
发明人： Yun-Jeong Hong , Scott A. Young , Maciej Turowski , Wallace H. Yokoyama , Marsha L. Langhorst , David R. Albers
IPC分类号： A23K1/16 , A23D9/00 , A23D7/00 , A23L1/39 , G01N33/03
CPC分类号： A23D9/007 , A23L29/262 , A23L33/20 , A23L33/24
摘要： A method of reducing the amount of saturated fatty acids capable of being absorbed by an animal body relative to the amount of unsaturated fatty acids capable of being absorbed by an animal body in or from a fat-containing food product comprises the steps of i) identifying a food product comprising one or more saturated fatty acids and one or more unsaturated fatty acids, and ii) incorporating one or more water-soluble cellulose derivatives in the food product or administering one or more water-soluble cellulose derivatives before, during or after the consumption of the food product.
摘要翻译：相对于能够被含脂肪的食品中的动物身体吸收的不饱和脂肪酸的量，减少能够被动物身体吸收的饱和脂肪酸的量的方法包括以下步骤：i）鉴定包含一种或多种饱和脂肪酸和一种或多种不饱和脂肪酸的食品，以及ii）将一种或多种水溶性纤维素衍生物掺入食品中或在所述食品中之前，期间或之后施用一种或多种水溶性纤维素衍生物消费食品。

14. 发明授权

US07824919B2 Method for analyzing activated polyethylene glycol compounds 失效
标题翻译：分析活性聚乙二醇化合物的方法
公开(公告)号：US07824919B2
公开(公告)日：2010-11-02
申请号：US11072763
申请日：2005-03-04
申请人： Ross A. Wallingford , Maciej Turowski
发明人： Ross A. Wallingford , Maciej Turowski
IPC分类号： G01N33/00
CPC分类号： G01N30/88 , A61K47/60 , G01N2030/8813 , G01N2030/8854 , Y10T436/200833 , Y10T436/2575
摘要： A chemical analysis method for the determination of RO(CH2CH2O)nH, RO(C2H4O)nA, and AO(C2H4O)nA in a mixture thereof, wherein R is an alkyl group, A is a functional group for coupling with a surface or a biologically active material or another thing of use and n is an integer greater than 10. The method includes the step of chromatographing a sample of the mixture by liquid chromatography under critical conditions to determine the relative amounts of RO(CH2CH2O)n H, RO(C2H4O)nA, and AO(C2H4O)nA in the mixture. In addition a chemical analysis method for the determination of RO(CH2CH2O)nH, RO(C2H4O)nA, and AO(C2H4O)nA in a mixture thereof, wherein R is an alkyl group, A is a functional group for coupling with a biologically active material and n is an integer greater than 10. The method includes two steps. The first step is derivatizing the A groups of the mixture with a derivatizing agent to form a derivatized mixture comprising RO(CH2CH2O)nH, RO(C2H4O)nAD, and DAO(C2H4O)nAD, wherein AD is the derivatized A group. The second step is chromatographing a sample of the derivatized mixture by liquid chromatography under critical conditions to determine the relative amounts of RO(CH2CH2O)nH, RO(C2H4O)nAD, and DAO(C2H4O)nAD in the derivatized mixture.
摘要翻译：用于在其混合物中测定RO（CH 2 CH 2 O）n H，RO（C 2 H 4 O）n A和AO（C 2 H 4 O）n A）的化学分析方法，其中R是烷基，A是与表面偶联的官能团生物活性物质或另一种使用的物质，n是大于10的整数。该方法包括在临界条件下通过液相色谱法分析混合物样品以测定RO（CH 2 CH 2 O）n H，RO（ C2H4O）nA和AO（C2H4O）nA。另外，用于测定其混合物中的RO（CH2CH2O）nH，RO（C2H4O）nA和AO（C2H4O）nA）的化学分析方法，其中R是烷基，A是与生物学偶联的官能团活性材料，n是大于10的整数。该方法包括两个步骤。第一步是用衍生剂衍生化A组混合物，形成包含RO（CH2CH2O）nH，RO（C2H4O）nAD和DAO（C2H4O）nAD的衍生化混合物，其中AD为衍生的A组。第二步是在临界条件下通过液相色谱法对衍生化混合物的样品进行色谱分析，以确定衍生化混合物中RO（CH2CH2O）nH，RO（C2H4O）nAD和DAO（C2H4O）nAD的相对量。

15. 发明申请

US20100041160A1 ANALYSIS OF HIGH MOLECULAR WEIGHT MPEG ALCOHOL COMPOSITIONS 审中-公开
标题翻译：高分子量MPEG酒精组合物的分析
公开(公告)号：US20100041160A1
公开(公告)日：2010-02-18
申请号：US12603708
申请日：2009-10-22
申请人： Chris Chappelow , Edward D. Daugs , Sterling C. Gatling , Kevin D. Sikkema , Maciej Turowski , Ross A. Wallingford
发明人： Chris Chappelow , Edward D. Daugs , Sterling C. Gatling , Kevin D. Sikkema , Maciej Turowski , Ross A. Wallingford
IPC分类号： G01N33/44
CPC分类号： C08G65/30 , C08G65/329
摘要： The invention is directed toward novel high molecular weight and high purity mPEG alcohol compositions as well as a process for obtaining said compositions by removing PEG diols from the mPEG alcohol after polymerization is complete.
摘要翻译：本发明涉及新的高分子量和高纯度mPEG醇组合物，以及通过在聚合完成后从mPEG醇中除去PEG二醇获得所述组合物的方法。

16. 发明申请

US20060198818A1 Method for analyzing activated polyethylene glycol compounds 失效
公开(公告)号：US20060198818A1
公开(公告)日：2006-09-07
申请号：US11072763
申请日：2005-03-04
申请人： Ross Wallingford , Maciej Turowski
发明人： Ross Wallingford , Maciej Turowski
IPC分类号： A61K31/765
CPC分类号： G01N30/88 , A61K47/60 , G01N2030/8813 , G01N2030/8854 , Y10T436/200833 , Y10T436/2575
摘要： A chemical analysis method for the determination of RO(CH2CH2O)nH, RO(C2H4O)nA, and AO(C2H4O)nA in a mixture thereof, wherein R is an alkyl group, A is a functional group for coupling with a surface or a biologically active material or another thing of use and n is an interger greater than 10. The method includes the step of chromatographing a sample of the mixture by liquid chromatography under critical conditions to determine the relative amounts of RO(CH2CH2O)n H, RO(C2H4O)nA, and AO(C2H4O)nA in the mixture. In addition a a chemical analysis method for the determination of RO(CH2CH2O)nH, RO(C2H4O)nA, and AO(C2H4O)nA in a mixture thereof, wherein R is an alkyl group, A is a functional group for coupling with a biologically active material and n is an interger greater than 10. The method includes two steps. The first step is derivatizing the A groups of the mixture with a derivatizing agent to form a derivatized mixture comprising RO(CH2CH2O)nH, RO(C2H4O)nAD, and DAO(C2H4O)nAD, wherein AD is the derivatized A group. The second step is chromatographing a sample of the derivatized mixture by liquid chromatography under critical conditions to determine the relative amounts of RO(CH2CH2O)nH, RO(C2H4O)nAD, and DAO(C2H4O)nAD in the derivatized mixture.

17. 发明申请

US20060045866A1 Novel high purity and high molecular weight mPEG alcohol compositions 审中-公开
标题翻译：新型高纯度和高分子量的mPEG醇组合物
公开(公告)号：US20060045866A1
公开(公告)日：2006-03-02
申请号：US10932629
申请日：2004-09-01
申请人： Chris Chappelow , Edward Daugs , Sterling Gatling , Kevin Sikkema , Maciej Turowski , Ross Wallingford
发明人： Chris Chappelow , Edward Daugs , Sterling Gatling , Kevin Sikkema , Maciej Turowski , Ross Wallingford
IPC分类号： A61K31/765 , C08G65/32
CPC分类号： C08G65/30 , C08G65/329
摘要： The invention is directed toward novel high molecular weight and high purity mPEG alcohol compositions as well as a process for obtaining said compositions by removing PEG diols from the mPEG alcohol after polymerization is complete.
摘要翻译：本发明涉及新的高分子量和高纯度mPEG醇组合物，以及通过在聚合完成后从mPEG醇中除去PEG二醇获得所述组合物的方法。

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