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11. 发明申请

WO2005065379A3 PESTICIDE FORMULATIONS WITH SUBSTITUTED BIOPOLYMERS AND ORGANIC POLYMERS 审中-公开
标题翻译：具有取代的生物聚合物和有机聚合物的农药配方
公开(公告)号：WO2005065379A3
公开(公告)日：2006-04-06
申请号：PCT/US2004043949
申请日：2004-12-29
申请人： HI CAP FORMULATIONS LTD , GRESSEL JONATHAN BEN , BURNET MICHAEL
发明人： GRESSEL JONATHAN BEN , BURNET MICHAEL
IPC分类号： A01N25/10 , A01N25/02 , A01N25/24
CPC分类号： A01N25/10 , A01N25/02 , A01N25/24 , A01N43/54 , A01N47/12 , A01N47/18 , A01N57/20 , A01N43/653 , A01N63/02 , A01N43/16 , A01N43/50 , A01N43/32 , A01N43/38 , A01N39/02
摘要： Functionalized polymers are mixed with pesticides to form semi-stable complexes with desirable field properties: reduced leaching in soil, improved leaf retention (rainfastness), selective unloading to roots and convenient packaging and application. Pesticides that may be so complexed include herbicides, insecticides (including compounds controlling non-insect arthropods and nematodes), bacteriocides, rodenticides, and fungicides. Polymers with which they may be complexed include derivatives of carbohydrates, amides, imines, alkanes, vinyls, styrenes or glycols. The polymers may be functionalized with chemical groups that exhibit ionic (amines, carboxyls), hydrophobic, complexing (e.g. metal chelating) and ligand binding interactions. The variously functionalized polymers may be mixed, grafted, or fused to obtain optimal properties. The polymer/pesticide formulations may be applied as granules, as suspensions or solutions in sprays, as foams, or as coats for seeds and fertilizers. The formulations may be applied to foliage, soil, irrigation water, construction materials (plastics, wood), seeding materials, grains, and buildings.
摘要翻译：官能化聚合物与农药混合以形成具有所需场性质的半稳定配合物：减少土壤浸出，提高叶片保持力（耐雨性），选择性卸载至根部，方便包装和施用。可能如此复杂的农药包括除草剂，杀虫剂（包括控制非昆虫节肢动物和线虫的化合物），杀菌剂，杀鼠剂和杀真菌剂。它们可能复合的聚合物包括碳水化合物，酰胺，亚胺，烷烃，乙烯基，苯乙烯或二醇的衍生物。可以用显示离子（胺，羧基），疏水性，络合（例如金属螯合）和配体结合相互作用的化学基团官能化聚合物。各种官能化聚合物可以混合，接枝或熔融以获得最佳性能。聚合物/农药制剂可以作为颗粒剂，作为喷雾剂中的悬浮液或溶液，泡沫或作为种子和肥料的涂层施用。制剂可以应用于叶子，土壤，灌溉水，建筑材料（塑料，木材），播种材料，谷物和建筑物。

12. 发明申请

WO2008152423A2 NEW MEDICAL USE 审中-公开
标题翻译：新医疗用途
公开(公告)号：WO2008152423A2
公开(公告)日：2008-12-18
申请号：PCT/GB2008050437
申请日：2008-06-11
申请人： DIOSAMINE DEV CORP , SEED MICHAEL PETER , MANCINI JOE ALBERT , DUGO LAURA , LEES MARGARET , BURNET MICHAEL , GUTKE HANS JUERGEN
发明人： SEED MICHAEL PETER , MANCINI JOE ALBERT , DUGO LAURA , LEES MARGARET , BURNET MICHAEL , GUTKE HANS JUERGEN
IPC分类号： A61K31/7016 , A61P19/02 , A61P29/00 , A61P37/00
CPC分类号： A61K31/7016 , A61K31/7024
摘要： The present invention relates to sulphated compounds containing one to twelve monosaccharide subunits, for the treatment or prevention of anon-gastrointestinal disease or conditionby gastrointestinal absorption, wherein none of the monosaccharide subunits is pyranosyl with N-substitution at the 2-position relative to the anomeric carbon of the pyranosyl subunit. The present invention also relates to corresponding methods of treating or preventing anon-gastrointestinal disease or condition. Additionally, the present invention relates to a method of modifying, or testing for a modification in,the level of a cytokine in vivo, ex vivoor in vitro, said method comprising contacting a sulphated compound with a cell, wherein the compound comprises at least one monosaccharide subunit. The present invention also relates to unit dosage forms comprising at least 2.5g of any of the above compounds, to unit dosage forms comprising the molar equivalent of at least 1 g of any of the above compounds in theirfree acid and/or base form, and to unit dosage forms comprising any of the above compounds other than sucralfate.Preferred compounds of the present invention are sucrose octasulphate and sucralfate.
摘要翻译：本发明涉及含有一至十二个单糖亚单位的硫酸化化合物，用于治疗或预防胃肠道疾病或胃肠道吸收的病症，其中单糖亚基中没有一个是相对于端基异构体在2-位上具有N-取代基的吡喃糖基吡喃糖基亚基的碳。本发明还涉及治疗或预防非胃肠道疾病或病症的相应方法。另外，本发明涉及体外细胞因子水平的修饰或测试方法，所述方法包括将硫酸化化合物与细胞接触，其中所述化合物包含至少一种单糖亚基。本发明还涉及包含至少2.5g上述化合物的单位剂型，其单位剂型包含摩尔当量至少1g上述无机酸和/或碱形式的上述化合物，以及包括除硫糖铝之外的任何上述化合物的单位剂型。本发明优选的化合物是蔗糖八硫酸盐和硫糖铝。

13. 发明申请

WO2008152421A2 NEW METHODS 审中-公开
标题翻译：新方法
公开(公告)号：WO2008152421A2
公开(公告)日：2008-12-18
申请号：PCT/GB2008050434
申请日：2008-06-11
申请人： DIOSAMINE DEV CORP , SEED MICHAEL PETER , MANCINI JOE ALBERT , DUGO LAURA , LEES MARGARET , BURNET MICHAEL , GUTKE HANS JUERGEN
发明人： SEED MICHAEL PETER , MANCINI JOE ALBERT , DUGO LAURA , LEES MARGARET , BURNET MICHAEL , GUTKE HANS JUERGEN
IPC分类号： A61K31/7008 , A61K31/7016 , A61K45/06 , A61P29/00 , A61P37/00
CPC分类号： A61K31/7028 , A61K31/7008 , A61K31/7016 , A61K31/702 , A61K31/708 , A61K45/06 , A61K2300/00
摘要： The present invention is directed to methods of modifying, or testing for a modification in,the level of a cytokine in vivo, ex vivo or in vitro, said method comprising contacting a compound or a pharmaceuticallyacceptable salt thereof with a cell, said compound comprising at least one monosaccharide subunit comprising a glycosidic amine group. The present invention is also directed to a method of modifying, or testing for a modification in, the level of VEGF in
摘要翻译：本发明涉及在体内，离体或体外修饰或测试细胞因子水平的方法，所述方法包括使化合物或其药学上可接受的盐与细胞接触，所述化合物包含在至少一个含糖苷基的单糖亚单位。本发明还涉及一种修饰或测试其中VEGF水平的修饰的方法

14. 发明专利

ES2904480T3 Detección de infecciones microbianas en heridas 未知
公开(公告)号：ES2904480T3
公开(公告)日：2022-04-05
申请号：ES17776643
申请日：2017-03-30
申请人： CONVATEC TECHNOLOGIES INC , SYNOVO GMBH , QUALIZYME DIAGNOSTICS GMBH & CO KG
发明人： BURNET MICHAEL , BOWLER PHILIP , WROE SARAH , STEVEN JADE , METCALF DANIEL GARY , PARSONS DAVID , BALLAMY LUCY , HEINZLE ANDREA , SIGL EVA , LUSCHNIG DANIEL , GAMERITH CLEMENS
IPC分类号： A61F13/00 , A61B5/00 , A61B10/00 , A61F13/02 , A61F13/15 , A61F13/84 , A61K9/70 , A61L15/00 , A61L15/16 , A61L15/38 , A61L15/42 , A61L15/56 , C12Q1/37 , G01N33/00
摘要： Un apósito para heridas que comprende a) una capa de contacto con la herida; b) una capa de reactivo que comprende una o más regiones de prueba, en donde la capa de reactivo está en comunicación fluida con la capa de contacto con la herida; y c) una capa exterior que se superpone a la capa de reactivo, en el que cada una o más regiones de prueba comprende una almohadilla reactiva y uno o más reactivos seleccionados de indicadores reactivos con enzimas que son conjugados de indicador de proteína que tienen la estructura de la Fórmula (I): en donde: A-B Fórmula (I) A es una región o resto de anclaje que une una región reactiva enzimática a la almohadilla de reactivo; y B es la región reactiva enzimática.

15. 发明专利

ECSP18081916A DETECCIÓN DE INFECCIONES MICROBIANAS EN HERIDAS 未知
公开(公告)号：ECSP18081916A
公开(公告)日：2019-02-28
申请号：ECDI201881916
申请日：2018-10-30
申请人： SYNOVO GMBH , QUALIZYME DIAGNOSTICS GMBH CO KG , CONVATEC TECHNOLOGIES INC
发明人： BURNET MICHAEL , PARSONS DAVID , HEINZLE ANDREA , BOWLER PHILIP , LUSCHNIG DANIEL , WROE SARAH , METCALF DANIEL GARY , BALLAMY LUCY , STEVEN JADE , SIGL EVA , GAMERITH CLEMENS
IPC分类号： A61F13/00 , A61F13/02 , A61F13/15 , A61K9/70 , A61L15/00 , A61L15/16 , A61L15/42
摘要： Se proporcionan en la presente, dispositivos indicadores de infección microbiana, que incluyen apósitos con indicadores, inserciones indicadoras independientes o discos que se pueden colocar libremente en el lugar de la herida o apósito, y aplicaciones de estos para mostrar una señal visible o detectable a un usuario al detectar un analito o biomarcador indicativo de una infección, tal como un cambio de color.

16. 发明专利

CO2018011705A2 Detección de infecciones microbianas en heridas 未知
公开(公告)号：CO2018011705A2
公开(公告)日：2019-02-08
申请号：CO2018011705
申请日：2018-10-29
申请人： SYNOVO GMBH , CONVATEC TECHNOLOGIES INC , QUALIZYME DIAGNOSTICS GMBH AND COKG
发明人： BURNET MICHAEL , BOWLER PHILIP , WROE SARAH , STEVEN JADE , METCALF DANIEL GARY , PARSONS DAVID , BALLAMY LUCY , HEINZLE ANDREA , SIGL EVA , LUSCHNIG DANIEL , GAMERITH CLEMENS
IPC分类号： A61F13/00 , A61F13/02 , A61F13/15 , A61K9/70 , A61L15/00 , A61L15/16 , A61L15/42
摘要： RESUMEN DE LA INVENCIÓN Se proporcionan en la presente dispositivos indicadores de infección microbiana, que incluyen apósitos con indicadores, inserciones indicadoras independientes o discos que se pueden colocar libremente en el lugar de la herida o apósito, y aplicaciones de estos para mostrar una señal visible o detectable a un usuario al detectar un analito o biomarcador indicativo de una infección, tal como un cambio de color.

17. 发明专利

AU2017239643A1 Detecting microbial infections in wounds 未知
公开(公告)号：AU2017239643A1
公开(公告)日：2018-11-15
申请号：AU2017239643
申请日：2017-03-30
申请人： CONVATEC TECHNOLOGIES INC , QUALIZYME DIAGNOSTICS GMBH AND CO KG , SYNOVO GMBH
发明人： BURNET MICHAEL , BOWLER PHILIP , WROE SARAH , STEVEN JADE , METCALF DANIEL GARY , PARSONS DAVID , BALLAMY LUCY , HEINZLE ANDREA , SIGL EVA , LUSCHNIG DANIEL , GAMERITH CLEMENS
IPC分类号： A61F13/00 , A61F13/02 , A61F13/15 , A61K9/70 , A61L15/00 , A61L15/16 , A61L15/42
摘要： Provided herein are microbial infection indicator devices, including dressing with indicators, standalone indicator inserts or disks that can be freely placed at a wound site or dressing, and applications thereof for displaying a visible or detectable signal to a user upon detection of an analyte or biomarker indicative of an infection, such as a color change.

18. 发明专利

UY37178A DETECCIÓN DE INFECCIÓN MICROBIANA EN HERIDAS 未知
公开(公告)号：UY37178A
公开(公告)日：2017-10-31
申请号：UY37178
申请日：2017-03-30
申请人： CONVATEC TECHNOLOGIES INC , QUALIZYME DIAGNOSTICS GMBH AND COKG , SYNOVO GMBH
发明人： BURNET MICHAEL , BOWLER PHILIP , WROE SARAH , STEVEN JADE , DANIEL GARY METCALF , PARSONS DAVID , BALLAMY LUCY , HEINZLE ANDREA , SIGL EVA , LUSCHNIG DANIEL , GAMERITH CLEMENS
IPC分类号： A61L15/22 , A61L15/38 , A61L15/56 , C12Q1/28 , C12Q1/34 , G01N33/52 , G01N33/58 , G01N33/68 , G01N33/84
摘要： Dispositivos indicadores de infecciones microbianas, que incluyen: vendajes con indicadores, insertos o discos independientes con indicadores que pueden colocarse independientemente en el lugar de la herida o en el vendaje, y sus aplicaciones para mostrar al usuario una senal visible o detectable al hallar un analito o biomarcador indicativo de una infeccion, como por ejemplo un cambio de color.

19. 发明专利

CA3019558A1 DETECTING MICROBIAL INFECTIONS IN WOUNDS 未知
公开(公告)号：CA3019558A1
公开(公告)日：2017-10-05
申请号：CA3019558
申请日：2017-03-30
申请人： CONVATEC TECHNOLOGIES INC , SYNOVO GMBH , QUALIZYME DIAGNOSTICS GMBH & CO KG
发明人： BURNET MICHAEL , BOWLER PHILIP , WROE SARAH , STEVEN JADE , METCALF DANIEL GARY , PARSONS DAVID , BALLAMY LUCY , HEINZLE ANDREA , SIGL EVA , LUSCHNIG DANIEL , GAMERITH CLEMENS
IPC分类号： A61F13/00 , A61F13/02 , A61F13/15 , A61K9/70 , A61L15/00 , A61L15/16 , A61L15/42
摘要： Provided herein are microbial infection indicator devices, including dressing with indicators, standalone indicator inserts or disks that can be freely placed at a wound site or dressing, and applications thereof for displaying a visible or detectable signal to a user upon detection of an analyte or biomarker indicative of an infection, such as a color change.

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