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11. 发明申请

WO2008130954A3 GRAFT FIXATION 审中-公开
标题翻译： GRAFT固定
公开(公告)号：WO2008130954A3
公开(公告)日：2009-10-22
申请号：PCT/US2008060401
申请日：2008-04-16
申请人： SMITH & NEPHEW INC , BROWN MALCOLM , HOWLING GRAEME , MONTES DE OCA BALDERAS HORACIO , FENWICK STEVE , COTTON NICHOLAS , BRUMFIELD DAVID
发明人： BROWN MALCOLM , HOWLING GRAEME , MONTES DE OCA BALDERAS HORACIO , FENWICK STEVE , COTTON NICHOLAS , BRUMFIELD DAVID
IPC分类号： A61L31/14
CPC分类号： A61L27/50 , A61B2017/00004 , A61B2017/00871 , A61F2/0811 , A61F2002/0852 , A61F2002/0858 , A61F2002/0864 , A61F2002/0888 , A61F2210/0014 , A61L27/14 , A61L2400/16
摘要： The present disclosure relates to an anchor for fixating a tissue graft to bone. The anchor includes a through hole extending an entire length of the anchor and a polymer composition having shape memory qualities. Other anchors and methods for fixating a tissue graft to bone are also disclosed.
摘要翻译：本公开涉及一种用于将组织移植物固定到骨头上的锚固件。该锚固件包括延伸锚固体的整个长度的通孔和具有形状记忆特性的聚合物组合物。还公开了用于将组织移植物固定到骨上的其它锚固件和方法。

12. 发明申请

WO2010117982A9 TISSUE GRAFT ANCHOR 审中-公开
标题翻译：组织格子锚
公开(公告)号：WO2010117982A9
公开(公告)日：2012-05-03
申请号：PCT/US2010030043
申请日：2010-04-06
申请人： SMITH & NEPHEW INC , MONTES HORACIO DE OCA , BROWN MALCOLM , HALL MICHAEL , HOWLING GRAEME
发明人： MONTES HORACIO DE OCA , BROWN MALCOLM , HALL MICHAEL , HOWLING GRAEME
IPC分类号： A61F2/08
CPC分类号： A61F2/0811 , A61F2002/0852 , A61F2002/0858 , A61F2002/0888 , A61F2002/30077 , A61F2210/0014 , A61F2210/0066 , A61F2250/0039
摘要： The present disclosure relates to a method of fixating a tissue graft. The method includes creating a hole in bone; inserting a tissue graft into the hole; inserting a cannulated anchor into the hole, the anchor comprising threads on an outer surface of the anchor and a polymer material including shape memory qualities; and providing energy to the anchor to deform the anchor and fixate the anchor to the bone, wherein upon deformation of the anchor, the threads of the anchor are substantially reduced thereby increasing contact between the anchor and the tissue graft. Anchors are also disclosed.
摘要翻译：本公开涉及固定组织移植物的方法。该方法包括在骨骼中形成孔; 将组织移植物插入孔中; 将插管锚栓插入孔中，锚固件包括锚固件的外表面上的螺纹和包括形状记忆特性的聚合物材料; 以及向所述锚固体提供能量以使所述锚固体变形并将所述锚固定到所述骨上，其中在所述锚固体变形时，所述锚固体的所述螺纹基本上减小，从而增加所述锚固体和所述组织移植物之间的接触。锚也被披露。

13. 发明申请

WO2009027640A3 DEVICE CAPABLE OF RELEASING CALCIUM LACTATE 审中-公开
标题翻译：释放钙乳杆菌的装置
公开(公告)号：WO2009027640A3
公开(公告)日：2010-01-28
申请号：PCT/GB2008002849
申请日：2008-08-22
申请人： SMITH & NEPHEW , HOWLING GRAEME , BROWN MALCOLM , HUTSON ELIZABETH
发明人： HOWLING GRAEME , BROWN MALCOLM , HUTSON ELIZABETH
IPC分类号： A61L31/12 , A61L31/14
CPC分类号： A61L27/54 , A61L27/58 , A61L2300/102 , A61L2300/412 , A61L2300/604
摘要： A device capable of delivering a therapeutically useful concentration of calcium lactate at a site of interest within the body of a subject.
摘要翻译：能够在受试者体内感兴趣的部位递送治疗有用的乳酸钙浓度的装置。

14. 发明申请

WO2008130956A3 KNEE AND SHOULDER JOINT PROSTHESIS 审中-公开
标题翻译： KNEE和SHOULDER JOINT PROSTHESIS
公开(公告)号：WO2008130956A3
公开(公告)日：2009-07-23
申请号：PCT/US2008060406
申请日：2008-04-16
申请人： SMITH & NEPHEW INC , HOWLING GRAEME , HUGHES DEAN , YEAGER JEFF , BROWN MALCOLM , MOSS RHIANNA , BETTENGA MASON , MONTES DE OCA BALDERAS HORACIO
发明人： HOWLING GRAEME , HUGHES DEAN , YEAGER JEFF , BROWN MALCOLM , MOSS RHIANNA , BETTENGA MASON , MONTES DE OCA BALDERAS HORACIO
IPC分类号： A61F2/38 , A61F2/40 , A61L31/14
CPC分类号： A61F2/40 , A61B2017/00287 , A61B2017/00871 , A61F2/30734 , A61F2/38 , A61F2002/30092 , A61F2002/30579 , A61F2210/0014
摘要： The present disclosure relates to prosthetic knee implants (100), components (101,102,103,104,105) of prosthetic knee implants, and methods of fixating the components to one another and, especially fixation of the implants to bone.
摘要翻译：本公开内容涉及假体膝盖植入物（100），假体膝盖植入物的部件（101,102,103,104,105）以及将部件彼此固定的方法，特别是将植入物固定在骨上。

15. 发明申请

WO2007020430A2 MULTIMODAL HIGH STRENGTH DEVICES AND COMPOSITES 审中-公开
标题翻译：多模高强度装置和复合材料
公开(公告)号：WO2007020430A2
公开(公告)日：2007-02-22
申请号：PCT/GB2006003047
申请日：2006-08-16
申请人： SMITH & NEPHEW , BROWN MALCOLM
发明人： BROWN MALCOLM
CPC分类号： A61L27/58 , A61L27/26 , A61L27/46 , A61L31/041 , A61L31/127 , A61L31/148 , C08L67/04
摘要： An oriented implantable biodegradable multimodal device is disclosed. The orientated implantable biodegradable multimodal device includes a blend of a first polymer component having a first molecular weight (mwt) together with at least a second polymer component having a mwt which is less than that of the first component. The polymer within the blend may be in a uniaxial, biaxial or triaxial orientation. Also disclosed is a composite thereof with matrix polymer, processes for the preparation thereof and the use thereof as an implantable biodegradable device such as a high strength trauma fixation device suitable for implantation into the human or animal body. As examples the high strength trauma device may take the form of plates, screws, pins, rods, anchors or scaffolds.
摘要翻译：公开了一种定向的可植入生物可降解多模式装置。取向的可植入生物可降解多模式装置包括具有第一分子量（mwt）的第一聚合物组分与至少第二聚合物组分具有小于第一组分的mwt的第二聚合物组分的共混物。共混物内的聚合物可以处于单轴，双轴或三轴取向。还公开了其与基质聚合物的复合物，其制备方法及其作为可植入生物可降解装置如适用于植入人体或动物体内的高强度创伤固定装置的用途。作为例子，高强度创伤装置可以采取板，螺钉，销，杆，锚或支架的形式。

16. 发明申请

WO2013050782A3 TAILORED POLYMERS 审中-公开
标题翻译：定制聚合物
公开(公告)号：WO2013050782A3
公开(公告)日：2013-07-18
申请号：PCT/GB2012052480
申请日：2012-10-05
申请人： SMITH & NEPHEW , UNIV BRADFORD
发明人： BROWN MALCOLM , BALDERAS HORACIO MONTES DE OCA , HALL MICHAEL ANDREW , CATON-ROSE PHILIP , COATES PHILIP DAVID , THOMPSON GLEN
IPC分类号： A61L31/06 , A61B17/04 , A61B17/06 , A61L31/12 , A61L31/14
CPC分类号： A61L24/046 , A61B17/00491 , A61B17/04 , A61B17/72 , A61B17/80 , A61B17/84 , A61B17/86 , A61B2017/00495 , A61B2017/00867 , A61B2017/00871 , A61B2017/00889 , A61B2017/00893 , A61L24/0021 , A61L31/06 , A61L31/14 , A61L31/141 , A61L31/16 , A61L2300/216 , A61L2400/16 , C08G63/08 , C08K5/06 , C08K5/10 , C08K5/3415 , C08K2201/018 , C08L67/04 , C08L2201/12
摘要： The present invention relates to shape memory polymers (SMP) and especially to shape memory polymer containing a water soluble non-reactive plasticiser and to uses thereof.
摘要翻译：本发明涉及形状记忆聚合物（SMP），尤其涉及含有水溶性非反应性增塑剂的记忆聚合物及其用途。

17. 发明公开

EP2344079A4 FRACTURE FIXATION SYSTEMS 有权
标题翻译：骨折固定系统
公开(公告)号：EP2344079A4
公开(公告)日：2015-11-18
申请号：EP09801085
申请日：2009-07-24
申请人： SMITH & NEPHEW INC
发明人： ROSE JOHN , JANNA SIED W , LEWIS MARK THOMAS , MARTIN CHARLES C , PATTERSON WILLIAM DEAN , RAINS JAMES K , GAN LU , DAGGER ANTHONY , WILHELM HOA L , AUSTIN GENE EDWARD , WILSON DARREN JAMES , CHIVERS ROBIN A , BROWN MALCOLM , HOWLING GRAEME , DOOTSON GINA , MONTES DE OCA BALDERAS HORACIO , MILNER RICHARD
IPC分类号： A61F2/28 , A61L24/00 , A61L27/14 , A61L27/26 , A61L27/46 , A61L27/56 , C08L75/04
CPC分类号： A61B17/7258 , A61B17/64 , A61B17/68 , A61B17/72 , A61B17/80 , A61B17/82 , A61B2017/00867 , A61F2/2846 , A61F2/30965 , A61F2002/30062 , A61F2210/0004 , A61F2210/0066 , A61F2210/0085 , A61F2240/001 , A61F2250/001 , A61F2310/00179 , A61L24/0084 , A61L27/46 , A61L27/56 , A61L27/58 , A61L2400/06 , C08L75/04
摘要： Systems for bone fracture repair are disclosed. One system includes a biocompatible putty that may be packed about a bone fracture to provide full loadbearing capabilities within days. The disclosed putties create an osteoconductive scaffold for bone regeneration and degrade over time to harmless resorbable byproducts. Fixation devices for contacting an endosteal wall of an intramedullary (IM) canal of a fractured bone are also disclosed. One such fixation device includes a woven elongated structure fabricated from resorbable polymer filaments. The woven elongated structure has resilient properties that allow the woven structure to be radially compressed and delivered to the IM canal using an insertion tube. When the insertion tube is removed, the woven structure expands towards its relaxed cross-sectional width to engage the endosteal wall. The woven elongated structure is impregnated with a resorbable polymer resin that cures in situ, or in the IM canal.

18. 发明公开

EP2344080A4 FRACTURE FIXATION SYSTEMS 有权
标题翻译：骨折固定系统
公开(公告)号：EP2344080A4
公开(公告)日：2015-05-13
申请号：EP09801083
申请日：2009-07-24
申请人： SMITH & NEPHEW INC
发明人： ROSE JOHN , LEWIS MARK THOMAS , MARTIN CHARLES C , PATTERSON WILLIAM DEAN , RAINS JAMES K , GAN LU , DAGGER ANTHONY , JANNA SIED W , WILHELM HOA L , BRUMFIELD DAVID L , CHIVERS ROBIN A , AUSTIN GENE EDWARD , WILSON DARREN JAMES , BROWN MALCOLM , HOWLING GRAEME , MONTES DE OCA BALDERAS HORACIO , DOOTSON GINA , MILNER RICHARD
IPC分类号： A61F2/28 , A61L27/14 , A61L27/26
CPC分类号： A61B17/7258 , A61B17/64 , A61B17/68 , A61B17/72 , A61B17/80 , A61B17/82 , A61B2017/00867 , A61F2/2846 , A61F2/30965 , A61F2002/30062 , A61F2210/0004 , A61F2210/0066 , A61F2210/0085 , A61F2240/001 , A61F2250/001 , A61F2310/00179 , A61L24/0084 , A61L27/46 , A61L27/56 , A61L27/58 , A61L2400/06 , C08L75/04
摘要： Systems for bone fracture repair are disclosed. One system includes a biocompatible putty that may be packed about a bone fracture to provide full loadbearing capabilities within days. The disclosed putties create an osteoconductive scaffold for bone regeneration and degrade over time to harmless resorbable byproducts. Fixation devices for contacting an endosteal wall of an intramedullary (IM) canal of a fractured bone are also disclosed. One such fixation device includes a woven elongated structure fabricated from resorbable polymer filaments. The woven elongated structure has resilient properties that allow the woven structure to be radially compressed and delivered to the IM canal using an insertion tube. When the insertion tube is removed, the woven structure expands towards its relaxed cross-sectional width to engage the endosteal wall. The woven elongated structure is impregnated with a resorbable polymer resin that cures in situ, or in the IM canal.

19. 发明申请

WO9728058A2 SECURITY CONTAINER WITH LOCKING LID 审中-公开
标题翻译：安全带有锁定的容器
公开(公告)号：WO9728058A2
公开(公告)日：1997-08-07
申请号：PCT/GB9700305
申请日：1997-01-31
申请人： BGF HEALTH CARE PRODUCTS LTD , GALTON FENZI MILES DOUGLAS MON , BROWN MALCOLM
发明人： GALTON-FENZI MILES DOUGLAS MON , BROWN MALCOLM
IPC分类号： B65D43/22 , B65D50/06 , B65D55/02
CPC分类号： B65D50/061 , Y10T70/5031 , Y10T70/7305
摘要： A container of the type requiring more than one operation to open, comprises a hollow body, a lid for the body, and a manually-operable member that is biassed into a first position at which the member engages the closed lid, and moveable against the bias into a second position at which the lid is releasable, wherein the lid is closeable when the member is in the first position.
摘要翻译：需要多于一个打开操作的类型的容器包括中空体，用于身体的盖子，以及可手动操作的构件，该构件被偏压到第一位置，在该第一位置，构件与闭合盖接合，并且能够抵抗偏压到盖可释放的第二位置，其中当构件处于第一位置时，盖可关闭。

20. 发明申请

WO2013050781A3 PROCESS FOR THE MANUFACTURE OF SHAPE MEMORY POLYMER MATERIAL 审中-公开
标题翻译：形状记忆聚合物材料的制造方法
公开(公告)号：WO2013050781A3
公开(公告)日：2013-08-08
申请号：PCT/GB2012052478
申请日：2012-10-05
申请人： SMITH & NEPHEW
发明人： BROWN MALCOLM , BALDERAS HORACIO MONTES DE OCA , HALL MICHAEL ANDREW , BULL ALAN WILLIAM , FARRAR DAVID FRANKLIN , CATON-ROSE PHILIP , COATES PHILIP DAVID , THOMPSON GLEN , MARTYN MICHAEL , WARD IAN MACMILLAN , BONNER MARK JAMES , HINE PETER JOHN , UNWIN PAUL , WOODHEAD MICHAEL
IPC分类号： A61B17/04 , A61B17/86 , A61L31/06 , A61L31/12 , A61L31/14
CPC分类号： B29C43/52 , A61B17/0401 , A61B17/122 , A61B17/844 , A61B17/864 , A61B17/8645 , A61B17/866 , A61B17/8685 , A61B2017/00004 , A61B2017/00411 , A61B2017/00867 , A61B2017/00871 , A61B2017/0403 , A61B2017/0404 , A61B2017/0412 , A61B2017/042 , A61B2017/0427 , A61B2017/0438 , A61B2017/0454 , A61B2017/8655 , A61F2/0811 , A61F2002/0835 , A61F2002/0888 , A61L31/06 , A61L31/127 , A61L31/14 , A61L31/141 , A61L31/148 , A61L31/16 , A61L2300/404 , A61L2300/41 , A61L2300/412 , A61L2300/414 , A61L2300/604 , A61L2400/16 , A61L2430/34 , B29K2101/12 , B29K2509/00 , C08J5/046 , C12Y304/21005 , C08L67/04
摘要： The present invention relates at least in part to methods for the manufacture of shape memory polymer (SMP) materials. Particularly, although not exclusive, the present invention relates to processes for the formation of complex shaped devices composed of shape memory polymer.
摘要翻译：本发明至少部分涉及用于制造形状记忆聚合物（SMP）材料的方法。特别地，尽管不是排他性的，本发明涉及形成由形状记忆聚合物组成的复杂形状装置的方法。

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