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11. 发明申请

US20050232812A1 Surface coating agents 有权
标题翻译：表面涂层剂
公开(公告)号：US20050232812A1
公开(公告)日：2005-10-20
申请号：US11157036
申请日：2005-06-20
申请人： Dale Swan
发明人： Dale Swan
IPC分类号： A61L27/28 , A61L27/34 , A61L29/08 , A61L33/00 , A61L33/04 , C07C309/42 , C09K3/00 , C12Q1/68 , G01N1/00
CPC分类号： A61L27/28 , A61L27/34 , A61L29/08 , A61L29/085 , A61L33/0088 , A61L33/04 , C07C309/42 , Y10T428/31504
摘要： Compounds useful as surface coating agents, including compounds of the formula: wherein X1 comprises a first photoreactive species; X2 comprises a second photoreactive species; Y comprises a nonpolymeric core molecule comprising an aromatic group; and Z comprises at least one charged group. The Y core can include an aromatic group such as a benzene radical, the charged groups Z can be independently selected from the organic acids that include sulfonic acid, carboxylic acid, and phosphoric acid, and the photoreactive species of X1 and X2 can independently be aryl ketones, such as those selected from the group acetophenone, benzophenone, anthraquinone, anthrone, and anthrone-like heterocycles, and their substituted derivatives. Examples of such coating agents include 4,5-bis(4-benzoylphenylmethyleneoxy) benzene-1,3-disulfonic acid di(potassium and/or sodium) salt, 2,5-bis(4-benzoylphenylmethyleneoxy) benzene-1,4-disulfonic acid di(potassium and/or sodium) salt (Compound II), and 2,5-bis(4-benzoylphenylmethyleneoxy) benzene-1-sulfonic acid monopotassium and/or monosodium salt.
摘要翻译：可用作表面包衣剂的化合物，包括下式的化合物：其中X 1包括第一光反应性物质; X 2包括第二光反应性物质; Y包含含有芳基的非聚合核心分子; Z包含至少一个带电基团。 Y核可以包括苯基等芳基，带电基团Z可以独立地选自包括磺酸，羧酸和磷酸的有机酸，并且X 1的光反应性物质， SUB＆gt;和X 2可以独立地为芳基酮，例如选自苯乙酮，二苯甲酮，蒽醌，蒽酮和蒽酮类杂环的芳基酮及其取代的衍生物。这种包衣剂的实例包括4,5-双（4-苯甲酰基苯基亚甲基氧基）苯-1,3-二磺酸二（钾和/或钠）盐，2,5-双（4-苯甲酰基苯基亚甲基氧基）苯-1,4- 盐（二盐酸盐）（化合物II）和2,5-双（4-苯甲酰基苯基亚甲基氧基）苯-1-磺酸单钾盐和/或单钠盐。

12. 发明申请

US20070292596A1 REAGENT AND METHOD FOR PROVIDING COATINGS ON SURFACES 失效
标题翻译：用于提供表面涂层的试剂和方法
公开(公告)号：US20070292596A1
公开(公告)日：2007-12-20
申请号：US11846955
申请日：2007-08-29
申请人： Ralph Chappa , Sean Stucke , Richard Amos , Terrence Everson , Stephen Chudzik , Dale Swan , Peter Duquette
发明人： Ralph Chappa , Sean Stucke , Richard Amos , Terrence Everson , Stephen Chudzik , Dale Swan , Peter Duquette
IPC分类号： A61L27/28 , A61L2/00
CPC分类号： B82Y30/00 , A61L27/34 , C09D4/00 , Y10S522/904 , Y10T428/249991 , Y10T428/249992 , C08F220/56 , C08F220/54
摘要： A grafting reagent and related method of using the reagent to form a polymeric layer on a support surface, and particularly a porous support surface, in a manner that provides and/or preserves desired properties (such as porosity) of the surface. The reagent and method can be used to provide a thin, conformable, uniform, uncrosslinked coating having desired properties onto the surface of a preformed, and particularly a porous, polymeric substrate. The method includes the steps of a) providing a porous support surface, b) providing a nonpolymeric grafting reagent comprising a photoinitator group, c) providing one or more polymerizable monomers adapted to be contacted with the surface, in the presence of the grafting reagent, and to be polymerized upon activation of the photoinitiator; and d) applying the grafting reagent and monomer(s) to the surface in a manner, and under conditions, suitable to coat the surface with the grafting reagent and to cause the polymerization of monomers to the surface upon activation of the grafting reagent.
摘要翻译：以提供和/或保留表面的所需性质（例如孔隙率）的方式使用试剂在支撑表面上，特别是多孔载体表面上形成聚合物层的接枝试剂和相关方法。试剂和方法可用于提供具有所需性质的薄的，一致的，均匀的未交联的涂层，其具有预先形成的，特别是多孔的聚合物基材的表面。该方法包括以下步骤：a）提供多孔载体表面，b）提供包含光引发剂基团的非聚合物接枝剂，c）在接枝剂存在下，提供适于与表面接触的一种或多种可聚合单体，并在激活光引发剂时聚合; 和d）以接枝试剂的方式和条件下将接枝试剂和单体施用于表面，并且在接枝试剂活化时使单体聚合成表面。

13. 发明申请

US20070065483A1 In vivo formed matrices including natural biodegradable polysaccharides and uses thereof 审中-公开
标题翻译：体内形成的基质包括天然可生物降解的多糖及其用途
公开(公告)号：US20070065483A1
公开(公告)日：2007-03-22
申请号：US11271238
申请日：2005-11-11
申请人： Stephen Chudzik , Dale Swan , Michael Burkstrand
发明人： Stephen Chudzik , Dale Swan , Michael Burkstrand
IPC分类号： A61K9/14 , C08G63/91
CPC分类号： A61L27/20 , A61K9/0024 , A61K9/0051 , A61K9/2027 , A61K9/205 , A61K47/34 , A61L27/34 , A61L27/54 , A61L27/58 , A61L29/085 , A61L29/16 , A61L31/042 , A61L31/10 , A61L31/16 , A61L2300/232 , A61L2300/252 , A61L2300/258 , A61L2300/604 , A61L2300/606 , A61L2420/02 , B05D1/36 , B05D7/52 , C08B31/006 , C08B31/04 , C08B33/02 , C08B33/04 , C08L3/02 , C08L3/12 , C09D103/02 , C09D103/18
摘要： In vivo formed matrices including natural biodegradable polysaccharides are described. The matrix is formed from a plurality of natural biodegradable polysaccharides having pendent coupling groups. The matrix can also include a bioactive agent which can be released to provide a therapeutic effect to a patient.
摘要翻译：描述了包括天然可生物降解多糖的体内形成的基质。该基质由多个具有侧联偶合基团的天然可生物降解多糖形成。基质还可以包括可以释放以向患者提供治疗效果的生物活性剂。

14. 发明申请

US20070065482A1 Articles including natural biodegradable polysaccharides and uses thereof 失效
标题翻译：包括天然可生物降解多糖的制品及其用途
公开(公告)号：US20070065482A1
公开(公告)日：2007-03-22
申请号：US11271237
申请日：2005-11-11
申请人： Stephen Chudzik , Dale Swan , Michael Burkstrand
发明人： Stephen Chudzik , Dale Swan , Michael Burkstrand
IPC分类号： A61F2/02 , A61K39/395
CPC分类号： A61L27/20 , A61K9/0024 , A61K9/0051 , A61K9/2027 , A61K9/205 , A61K47/34 , A61L27/34 , A61L27/54 , A61L27/58 , A61L29/085 , A61L29/16 , A61L31/042 , A61L31/10 , A61L31/16 , A61L2300/232 , A61L2300/252 , A61L2300/258 , A61L2300/604 , A61L2300/606 , A61L2420/02 , B05D1/36 , B05D7/52 , C08B31/006 , C08B31/04 , C08B33/02 , C08B33/04 , C08L3/02 , C08L3/12 , C09D103/02 , C09D103/18
摘要： Medical articles having a body member including natural biodegradable polysaccharides are described. The body member is formed from a plurality of natural biodegradable polysaccharides having pendent coupling groups. The body member can also include a bioactive agent which can be released to provide a therapeutic effect to a patient.
摘要翻译：描述具有包括天然可生物降解多糖的主体成分的医疗制品。身体构件由多个具有侧联偶联基团的天然可生物降解多糖形成。身体构件还可以包括可以释放以向患者提供治疗效果的生物活性剂。

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