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11. 发明申请

US20150038946A1 CATHETERS WITH HIGH-PURITY FLUOROPOLYMER ADDITIVES 有权
标题翻译：高透明荧光增白剂的导管
公开(公告)号：US20150038946A1
公开(公告)日：2015-02-05
申请号：US14519589
申请日：2014-10-21
申请人： Raymond Lareau , Benjamin Bell , J. Paul Santerre , Jeannette Ho
发明人： Raymond Lareau , Benjamin Bell , J. Paul Santerre , Jeannette Ho
IPC分类号： A61L29/04 , A61L29/18 , A61L33/06 , A61M25/00
CPC分类号： A61L29/041 , A61L29/049 , A61L29/14 , A61L29/18 , A61L33/062 , A61L33/064 , A61L2300/802 , A61M25/0017 , A61M25/0021 , A61M2025/0056 , C08L75/04 , C08L27/12
摘要： The present invention provides catheter compositions that provide anti-thrombogenic properties while not adversely impacting mechanical properties. All embodiments of the present invention comprise a catheter that comprises a fluoropolymer additive with specific compositions and/or purity levels.
摘要翻译：本发明提供了提供抗血栓形成性质而不会不利地影响机械性能的导管组合物。本发明的所有实施方案包括导管，其包含具有特定组成和/或纯度水平的含氟聚合物添加剂。

12. 发明授权

US08603067B2 High flow catheters 有权
公开(公告)号：US08603067B2
公开(公告)日：2013-12-10
申请号：US13474004
申请日：2012-05-17
申请人： Raymond Lareau , Benjamin Bell , Mark Girard
发明人： Raymond Lareau , Benjamin Bell , Mark Girard
IPC分类号： A61M25/00 , A61M25/16 , A61M25/18
CPC分类号： A61M25/0026 , A61M25/0023 , A61M25/0028 , A61M25/0029 , A61M25/0043 , A61M25/0054 , A61M25/0068 , A61M2025/0024 , A61M2025/0037 , A61M2206/20
摘要： A catheter that comprises a hub, an elongated conduit, and at least one lumen therein. The lumen includes a proximal lumen section, a distal lumen section, and an intermediate lumen section extending between the proximal and distal lumen sections. The cross-sectional dimension of the intermediate lumen section is less than the cross-sectional dimension of the distal lumen section. In one embodiment, the cross-sectional dimension of the intermediate lumen section is less than the cross-sectional dimension of the proximal lumen section. In certain embodiments, the lumen tapers from the distal and/or proximal lumen sections to the intermediate lumen section.

13. 发明申请

US20120245528A1 CATHETER WITH POROUS CUFF 审中-公开
标题翻译：多孔铜管
公开(公告)号：US20120245528A1
公开(公告)日：2012-09-27
申请号：US13053386
申请日：2011-03-22
申请人： Raymond Lareau , Benjamin Bell , Mark Girard
发明人： Raymond Lareau , Benjamin Bell , Mark Girard
IPC分类号： A61M25/04
CPC分类号： A61M25/02 , A61M25/0017 , A61M2025/0293
摘要： Disclosed is a catheter that includes a porous element. In one embodiment, the porous element comprises the same polymeric material as the catheter shaft. In another embodiment, the porous element comprises a porous polyurethane material.
摘要翻译：公开了一种包括多孔元件的导管。在一个实施例中，多孔元件包括与导管轴相同的聚合物材料。在另一个实施方案中，多孔元件包括多孔聚氨酯材料。

14. 发明申请

US20120232496A1 High Flow Catheters 有权
标题翻译：高流量导管
公开(公告)号：US20120232496A1
公开(公告)日：2012-09-13
申请号：US13474004
申请日：2012-05-17
申请人： Raymond Lareau , Benjamin Bell , Mark Girard
发明人： Raymond Lareau , Benjamin Bell , Mark Girard
IPC分类号： A61M25/14 , A61M25/16
CPC分类号： A61M25/0026 , A61M25/0023 , A61M25/0028 , A61M25/0029 , A61M25/0043 , A61M25/0054 , A61M25/0068 , A61M2025/0024 , A61M2025/0037 , A61M2206/20
摘要： A catheter that comprises a hub, an elongated conduit, and at least one lumen therein. The lumen includes a proximal lumen section, a distal lumen section, and an intermediate lumen section extending between the proximal and distal lumen sections. The cross-sectional dimension of the intermediate lumen section is less than the cross-sectional dimension of the distal lumen section. In one embodiment, the cross-sectional dimension of the intermediate lumen section is less than the cross-sectional dimension of the proximal lumen section. In certain embodiments, the lumen tapers from the distal and/or proximal lumen sections to the intermediate lumen section.
摘要翻译：一种导管，包括一个轮毂，一个细长导管和至少一个内腔。内腔包括近端管腔部分，远端管腔部分和在近端和远端管腔部分之间延伸的中间管腔部分。中间管腔部分的横截面尺寸小于远侧管腔部分的横截面尺寸。在一个实施例中，中间管腔部分的横截面尺寸小于近端管腔部分的横截面尺寸。在某些实施例中，管腔从远端和/或近端管腔部分逐渐变细到中间管腔部分。

15. 发明授权

US08034066B2 Multi-layer medical balloons 有权
标题翻译：多层医用气球
公开(公告)号：US08034066B2
公开(公告)日：2011-10-11
申请号：US11228854
申请日：2005-09-15
申请人： Kara Goeken , Raymond Lareau , Fuh-Sheng Chen , Show-Mean Wu
发明人： Kara Goeken , Raymond Lareau , Fuh-Sheng Chen , Show-Mean Wu
IPC分类号： A61B17/22
CPC分类号： A61B17/320725 , A61B2017/22061 , A61M25/1002 , A61M2025/1075 , A61M2025/1086
摘要： The invention relates to multi-layer medical balloons. In one aspect, a medical device includes an inflatable balloon. The inflatable balloon includes a first layer including a material having a first modulus of elasticity, and a second layer adjacent the first layer, the second layer including a material having a second modulus of elasticity that differs from the first modulus of elasticity by at least about 2,000 psi. A cutting element is carried by the balloon.
摘要翻译：本发明涉及多层医用气囊。在一个方面，医疗装置包括可充气气囊。可膨胀气囊包括第一层，其包括具有第一弹性模量的材料和与第一层相邻的第二层，第二层包括具有与第一弹性模量不同的第二弹性模量至少约为 2,000 psi。切割元件由气球承载。

16. 发明申请

US20080097395A1 Catheter shaft including a metallic tapered region 有权
标题翻译：导管轴包括金属锥形区域
公开(公告)号：US20080097395A1
公开(公告)日：2008-04-24
申请号：US11522561
申请日：2006-09-18
申请人： Mark L. Adams , Todd Beaupre , Christopher Nardone , Mark Girard , Raymond Lareau
发明人： Mark L. Adams , Todd Beaupre , Christopher Nardone , Mark Girard , Raymond Lareau
IPC分类号： A61M25/00 , A61M25/16
CPC分类号： A61M25/0021 , A61M25/0023 , A61M25/0043 , A61M25/0054 , A61M25/0068 , A61M25/007 , A61M25/008
摘要： A catheter shaft including a metallic tubular member including a plurality of apertures formed in the tubular wall of the metallic tubular member to provide a desired degree of flexibility to the metallic tubular member. The metallic tubular member includes a tapered region intermediate a region and a second, reduced diameter region relative to the first region.
摘要翻译：一种导管轴，包括金属管状构件，其包括形成在金属管状构件的管状壁中的多个孔，以向金属管状构件提供期望程度的柔性。金属管状构件包括相对于第一区域的中间区域和第二减小直径区域的锥形区域。

17. 发明申请

US20060106351A1 Selective surface modification of catheter tubing 有权
公开(公告)号：US20060106351A1
公开(公告)日：2006-05-18
申请号：US10987010
申请日：2004-11-12
申请人： Raymond Lareau
发明人： Raymond Lareau
IPC分类号： A61M25/00
CPC分类号： A61M25/0045 , A61M25/0009 , A61M25/0054 , A61M2025/0046 , A61M2025/0047 , A61M2025/006 , B28B3/20 , B29C47/0023 , B29C47/0026 , B29C47/0028 , B29C47/065 , B29C47/0811 , B29C47/26 , B29C47/28 , B29C47/56
摘要： A catheter shaft and methods for making and using the same. The catheter shaft may include a core portion, a cap portion, and one or more lumens. The cap portion may be disposed on or over a section of the core portion and define a region with a different exterior or interior surface characteristic. For example, the cap portion may define a lubricious region along the catheter shaft. Manufacturing the catheter shaft may include a modified co-extrusion process that incorporates a flow valve on at least one of the material supply lines so that the supply line can be regulated by a user.

18. 发明授权

US09789229B1 Catheter shaft with enhanced platelet anti-adhesion surfaces 有权
公开(公告)号：US09789229B1
公开(公告)日：2017-10-17
申请号：US14215145
申请日：2014-03-17
申请人： Raymond Lareau , Benjamin Bell , Jeannette Ho , J. Paul Santerre
发明人： Raymond Lareau , Benjamin Bell , Jeannette Ho , J. Paul Santerre
IPC分类号： A61L29/04 , C08G18/10 , C08G18/48 , C08L75/04 , C08G18/73 , A61L29/12 , A61L29/18 , A61L29/14 , A61M25/00 , A61L33/06
CPC分类号： A61L29/126 , A61L29/049 , A61L29/14 , A61L29/18 , A61L33/062 , A61L2300/802 , A61M25/0017 , C08L75/04
摘要： A venous access catheter shaft and method of using and manufacturing such a catheter is provided. In one aspect of the invention, a catheter is provided comprising a base polymer having a Shore A durometer of 85A or lower, with 2.0% percent by weight of surface modifier, and a radiopaque filler comprising between 20-40 percentage by weight. In another aspect of the invention, a method reducing thrombus accumulation on a venous access catheter is provided wherein the catheter surface's resistance to thrombus formation is enhanced during indwell time by lowering the durometer rating of the base polymer of the catheter without increasing the amount of surface modifier additive. In another aspect of the invention, a method of manufacturing a catheter shaft is provided, wherein the shaft is formed comprising a base polymer having a Shore A durometer of 85A or lower, with 2.0% percent by weight of surface modifier, and a radiopaque filler comprising 30% by weight barium sulfate, and optionally a colorant of 0.2% weight.

19. 发明授权

US09447892B2 Pressure activated valve for high flow rate and pressure venous access applications 有权
标题翻译：用于高流量和压力静脉进入应用的压力激活阀
公开(公告)号：US09447892B2
公开(公告)日：2016-09-20
申请号：US13566386
申请日：2012-08-03
申请人： Raymond Lareau , Mark Girard , Benjamin Bell
发明人： Raymond Lareau , Mark Girard , Benjamin Bell
IPC分类号： A61M39/24 , F16K15/14
CPC分类号： A61M39/24 , A61M2039/2426 , A61M2039/246 , F16K15/147 , F16K27/0209 , Y10T137/7881
摘要： A valve having a first housing including a first lumen extending therethrough and a first disk-facing surface, a second housing including a second lumen extending therethrough and a second disk-facing surface, where the second housing is coupled to the first housing so that the second disk-facing surface faces the first disk-facing surface. A flexible disk has at least a portion of an outer edge of the disk extending away from a plane of a central portion of the disk, the outer edge contacting the first disk-facing surface, the disk including a slit extending therethrough which, when acted upon by a fluid pressure of at least a threshold level opens to permit fluid flow between the first and second lumens and which, when acted upon by a fluid pressure less than the threshold level, prevents fluid flow between the first and second lumens.
摘要翻译：一种具有第一壳体的阀，所述第一壳体包括延伸穿过其中的第一内腔和第一盘对面的表面，第二壳体包括延伸穿过其中的第二腔和第二盘对面的表面，其中所述第二壳体联接到所述第一壳体，第二面向盘的表面面向第一面向盘的表面。柔性盘具有盘的外边缘的至少一部分远离盘的中心部分的平面延伸，外边缘接触第一面向盘的表面，盘包括延伸穿过其中的狭缝，当作用时通过至少阈值水平的流体压力打开以允许流体在第一和第二流明之间流动，并且当由低于阈值水平的流体压力作用时，防止流体在第一和第二流明之间流动。

20. 发明授权

US09440047B1 Systems and methods for catheter tip placement using ECG 有权
标题翻译：使用心电图导管尖端放置的系统和方法
公开(公告)号：US09440047B1
公开(公告)日：2016-09-13
申请号：US14211879
申请日：2014-03-14
申请人： Lambertus Wilhelmus Johannes Elberse , Franciscus Ludovicus Maria Johannes Veldhuijzen , Raymond Lareau , Mark Girard , Damon Casiello
发明人： Lambertus Wilhelmus Johannes Elberse , Franciscus Ludovicus Maria Johannes Veldhuijzen , Raymond Lareau , Mark Girard , Damon Casiello
IPC分类号： A61B5/042 , A61M25/01
CPC分类号： A61B5/061 , A61B5/0456 , A61B34/20 , A61M25/0102 , A61M2025/0056 , A61M2025/0166
摘要： A system and method for catheter placement using ECG is provided. In certain embodiments, the system and method can generate a patient specific window for tracking a characteristic of an ECG waveform, such as the amplitude of a P-wave. The patient specific window can be utilized in a system and method for assisting in the placement of a catheter within a patient. In other embodiments, a tip location algorithm can be used with an anti-thrombogenic catheter and an intravascular electrode assembly for maintaining a high resolution intravascular signal in an ECG based catheter tip placement system.
摘要翻译：提供一种使用ECG进行导管放置的系统和方法。在某些实施例中，系统和方法可以产生用于跟踪ECG波形的特征的患者特定窗口，例如P波的幅度。患者具体窗口可以用于辅助将导管放置在患者体内的系统和方法中。在其他实施例中，尖端位置算法可以与抗血栓形成导管和血管内电极组件一起使用，用于在基于ECG的导管末端放置系统中维持高分辨率血管内信号。

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