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    • 11. 发明申请
    • Method for non-invasilvely determining the relative levels of two biological substances
    • 非侵入性测定两种生物物质相对水平的方法
    • US20050074810A1
    • 2005-04-07
    • US10481676
    • 2002-06-17
    • Richard GuyMaria Delgado-Charro
    • Richard GuyMaria Delgado-Charro
    • A61N1/30G01N33/53
    • A61N1/30A61B5/14532A61B5/1486
    • The method for non-invasively determining the relative levels of two substances present in a biological system includes the steps of extracting by reverse iontophoresis charged and uncharged substances from said biological system, and collecting said substances, analysing the collected amount of a first extracted substance and a second extracted substance and determining the extraction ratio of the first substance to the second substance to determine their relative levels in the biological system. When the first and second substances are both analytes susceptible to changes in their concentration in the biological system, this method provides information about the relative concentrations of the two substances in the biological system. When the first substance is an analyte susceptible to changes in its concentration in the biological system and the second substance has a substantially constant concentration in the biological system, the second subtance acts as an internal standard and the extraction ratio becomes a direct measurement of the physiological level of the first substance in the biological system. A iontophoretic sampling device for monitoring the relative levels of two substances present in a biological system is also disclosed.
    • 用于非侵入性地确定存在于生物系统中的两种物质的相对水平的方法包括以下步骤:通过反向离子电渗法从所述生物系统中提取带电荷和不带电荷的物质,并收集所述物质,分析第一提取物质的收集量和 第二提取物质并确定第一物质与第二物质的提取比例,以确定其在生物系统中的相对水平。 当第一种和第二种物质都是分析物易于在生物系统中浓度变化时,该方法提供有关生物系统中两种物质的相对浓度的信息。 当第一物质是易受其在生物系统中的浓度变化的分析物,并且第二物质在生物系统中具有基本恒定的浓度时,第二物质作为内标,并且提取率成为生理学上的直接测量 生物系统中第一物质的水平。 还公开了用于监测存在于生物系统中的两种物质的相对水平的离子电渗取样装置。
    • 14. 发明授权
    • Apparatus for stretching canvas and like materials
    • 用于拉伸帆布和类似材料的装置
    • US4180246A
    • 1979-12-25
    • US956076
    • 1978-10-30
    • Richard Guy
    • Richard Guy
    • B44D3/18D06F59/08B66F19/00
    • B44D3/185D06F59/08
    • An apparatus for stretching canvas and like materials that must be stretch-mounted to a supporting stretcher-frame structure generally comprising a four-sided wooden frame member, whereby the canvas is stapled thereto. The apparatus comprises an elongated, horizontal, tubular, structural-beam member affixed at both ends to vertical supports; and has an elongated, biased, clamping bar member hingedly mounted along the full length of the upper surface of the structural-beam member, the clamping bar being provided with a canvas-securing keeper located thereon to engage, under tension, one edge of the canvas when the canvas is positioned between the clamping bar and the beam member. The operation of the clamping bar is provided by a spring-loaded handle and a trigger-release device, the trigger-release device being adapted to be adjustably positioned on either side of the canvas-stretcher frame during the operation thereof. Further included is a pair of stretcher-bar holders which are arranged to be slidably received on the beam member and to be adjustable to support various sizes of stretcher frames.
    • 一种用于拉伸帆布和类似材料的装置,其必须被拉伸安装到通常包括四边框架构件的支撑拉架框架结构,由此帆布被装订到其上。 该装置包括在两端固定到垂直支撑件上的细长水平的管状结构梁构件; 并且具有沿着结构梁构件的上表面的整个长度铰接地安装的细长偏压的夹紧杆构件,夹紧杆设置有位于其上的帆布固定保持器,以在张力下接合 当画布位于夹紧杆和梁构件之间时,画布。 夹紧杆的操作由弹簧加载的手柄和触发释放装置提供,触发释放装置适于在其操作期间可调节地定位在画布拉伸框架的任一侧上。 还包括一对担架杆保持器,其布置成可滑动地容纳在梁构件上并且可调节以支撑各种尺寸的担架框架。