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    • 17. 发明申请
    • ELECTROCHEMICAL POTENTIOMETRIC SENSING WITHOUT REFERENCE ELECTRODE
    • 无参考电极的电化学电位感测
    • US20110208457A1
    • 2011-08-25
    • US13061110
    • 2009-08-24
    • Matthias MerzYouri Victorovitch PonomarevGilberto Curatola
    • Matthias MerzYouri Victorovitch PonomarevGilberto Curatola
    • G06F19/00
    • G01N27/4148G01N27/4145
    • The invention relates to a method of determining a charged particle concentration in an analyte (100), the method comprising steps of: i) determining at least two measurement points of a surface-potential versus interface-temperature curve (c1, c2, c3, c4), wherein the interface temperature is obtained from a temperature difference between a first interface between a first ion-sensitive dielectric (Fsd) and the analyte (100) and a second interface between a second ion-sensitive dielectric (Ssd) and the analyte (100), and wherein the surface-potential is obtained from a potential difference between a first electrode (Fe) and a second electrode (Se) onto which said first ion-sensitive dielectric (Fsd) and said second ion-sensitive dielectric (Ssd) are respectively provided, And ii) calculating the charged particle concentration from locations of the at least two measurement points of said curve (c1, c2, c3, c4). This method, which still is a potentiometric electrochemical measurement, exploits the temperature dependency of a surface-potential of an ion-sensitive dielectric in an analyte. The invention further provides an electrochemical sensor deny for determining a charged particle concentration in an analyte. The invention also provides various sensors which can be used to determine the charged particle concentration, i.e. EGFET's and EIS capacitors.
    • 本发明涉及一种测定分析物(100)中带电粒子浓度的方法,所述方法包括以下步骤:i)确定表面电位对界面温度曲线(c1,c2,c3,c3)的至少两个测量点, c4),其中所述界面温度是由第一离子敏感电介质(Fsd)和分析物(100)之间的第一界面与第二离子敏感电介质(Ssd)与分析物之间的第二界面 (100),并且其中所述表面电位由所述第一离子敏感电介质(Fsd)和所述第二离子敏感电介质(Ssd)上的第一电极(Fe)和第二电极(Se)之间的电位差获得, ),和ii)从所述曲线(c1,c2,c3,c4)的至少两个测量点的位置计算带电粒子浓度。 这种仍然是电位电化学测量的方法利用分析物中离子敏感电介质的表面电位的温度依赖性。 本发明还提供了一种用于确定分析物中带电粒子浓度的电化学传感器。 本发明还提供可用于确定带电粒子浓度的各种传感器,即EGFET和EIS电容器。