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11. 发明授权

US09295786B2 Needle protective device for subcutaneous sensors 有权
公开(公告)号：US09295786B2
公开(公告)日：2016-03-29
申请号：US12154935
申请日：2008-05-28
申请人： Rebecca K. Gottlieb , Rajiv Shah , Katherine T. Wolfe , Eric Allan Larson
发明人： Rebecca K. Gottlieb , Rajiv Shah , Katherine T. Wolfe , Eric Allan Larson
IPC分类号： A61B5/05 , A61M5/32 , A61B5/00 , A61M5/158 , A61M25/06 , A61M37/00
CPC分类号： A61B5/14532 , A61B5/1473 , A61B5/6849 , A61B17/3496 , A61M5/158 , A61M5/3243 , A61M25/0612 , A61M37/0069 , A61M2005/1585 , A61M2005/3247
摘要： An introducer is provided for introducing a sensor into the body of a patient. The introducer connects to a sensor hub. When the sensor hub and introducer are connected, the introducer needle is exposed. When the sensor hub and introducer are disconnected, a needle cover and the needle move with respect to each other so that the needle cover substantially covers the needle, protecting a user from being injured by the needle.

12. 发明申请

US20090299301A1 Needle protective device for subcutaneous sensors 有权
标题翻译：用于皮下传感器的针头保护装置
公开(公告)号：US20090299301A1
公开(公告)日：2009-12-03
申请号：US12154935
申请日：2008-05-28
申请人： Rebecca K. Gottlieb , Rajiv Shah , Katherine T. Wolfe , Eric Allan Larson
发明人： Rebecca K. Gottlieb , Rajiv Shah , Katherine T. Wolfe , Eric Allan Larson
IPC分类号： A61M5/32 , A61B5/055
CPC分类号： A61B5/14532 , A61B5/1473 , A61B5/6849 , A61B17/3496 , A61M5/158 , A61M5/3243 , A61M25/0612 , A61M37/0069 , A61M2005/1585 , A61M2005/3247
摘要： An introducer is provided for introducing a sensor into the body of a patient. The introducer connects to a sensor hub. When the sensor hub and introducer are connected, the introducer needle is exposed. When the sensor hub and introducer are disconnected, a needle cover and the needle move with respect to each other so that the needle cover substantially covers the needle, protecting a user from being injured by the needle.
摘要翻译：提供导引器用于将传感器引入患者体内。导引器连接到传感器集线器。当传感器毂和导引器连接时，导引针被暴露。当传感器毂和导引器断开时，针盖和针相对于彼此移动，使得针盖基本上覆盖针，保护使用者免受针受伤。

13. 发明申请

US20110288388A1 MULTI-CONDUCTOR LEAD CONFIGURATIONS USEFUL WITH MEDICAL DEVICE SYSTEMS AND METHODS FOR MAKING AND USING THEM 审中-公开
标题翻译：具有医疗设备系统的多导体引线配置及其制造和使用方法
公开(公告)号：US20110288388A1
公开(公告)日：2011-11-24
申请号：US12949038
申请日：2010-11-18
申请人： Rajiv Shah , Rebecca K. Gottlieb , Katherine T. Wolfe
发明人： Rajiv Shah , Rebecca K. Gottlieb , Katherine T. Wolfe
IPC分类号： A61B5/145 , H01B7/08 , H01R43/16 , G01N27/00
CPC分类号： A61B5/14503 , A61B5/14532 , A61B2562/222 , A61N1/05 , A61N1/08 , Y10T29/49204
摘要： A multiple-conductor electrical lead for use with medical device systems and a method of manufacture is disclosed. The multiple-conductor electrical lead comprises a central core and has at least one conductor, typically in the form of a ribbon cable, coiled around it along its length. Typically one or more ribbon cables coiled around a central core each comprise a plurality of separate electrical conductors both coupled together along their lengths in series and electrically insulated from one another with an insulating material. The material of the central core, e.g. polyester, stainless steel, nickel titanium, and the structural configuration, e.g. wrapping pitch of the ribbon cable around the central core and number of ribbon cables, are selected based on desired mechanical characteristics. Such multiple-conductor electrical leads are useful, for example, with analyte sensor systems such as amperometric glucose sensor systems used in the management of diabetes.
摘要翻译：公开了一种用于医疗设备系统的多导体电引线和制造方法。多导体电引线包括中心芯并且具有通常为带状电缆形式的至少一个导体，其沿其长度卷绕在其周围。通常，围绕中心芯线卷绕的一个或多个带状电缆每个包括多个分离的电导体，两个单独的电导体沿着它们的长度串联连接在一起并且用绝缘材料彼此电绝缘。中心芯的材料，例如聚酯，不锈钢，镍钛，以及结构构型，例如。基于期望的机械特性选择带状电缆围绕中心芯和带状电缆的数量的缠绕间距。这种多导体电引线例如可用于分析物传感器系统，例如用于糖尿病管理的电流葡萄糖传感器系统。

14. 发明申请

US20100191087A1 SENSING SYSTEM WITH AUXILIARY DISPLAY 审中-公开
标题翻译：带辅助显示器的感应系统
公开(公告)号：US20100191087A1
公开(公告)日：2010-07-29
申请号：US12758391
申请日：2010-04-12
申请人： Cary D. Talbot , John J. Mastrototaro , Rajiv Shah , Edward Chernoff , John C. Mueller, JR. , Varaz Shahmirian , Richard E. Purvis , Wayne A. Morgan , Rebecca K. Gottlieb
发明人： Cary D. Talbot , John J. Mastrototaro , Rajiv Shah , Edward Chernoff , John C. Mueller, JR. , Varaz Shahmirian , Richard E. Purvis , Wayne A. Morgan , Rebecca K. Gottlieb
IPC分类号： A61B5/145
CPC分类号： A61B5/0002 , A61B5/145 , A61B5/14532 , A61B5/412 , A61B2560/0209 , A61B2560/0443 , A61B2560/0456
摘要： A system is provided for sensing blood glucose data of a patient. The system includes a sensor, user interface, and an optional auxiliary device. If the connection between the sensor and user interface is by a wire, the sensor remains powered when the wire is disconnected. The communication between the sensor and the user interface may be wireless. The auxiliary device can be a patient monitor or other display or signal device, which displays information about the blood glucose data collected by the sensor. The sensor is connected to sensor electronics, which include a sensor power supply, a voltage regulator, and optionally a memory and processor.
摘要翻译：提供了一种用于感测患者血糖数据的系统。该系统包括传感器，用户界面和可选的辅助设备。如果传感器和用户界面之间的连接是通过导线连接的，那么当导线断开时，传感器保持供电。传感器和用户界面之间的通信可能是无线的。辅助装置可以是患者监视器或其他显示器或信号装置，其显示关于由传感器收集的血糖数据的信息。传感器连接到传感器电子设备，其中包括传感器电源，电压调节器以及可选的存储器和处理器。

15. 发明申请

US20100191086A1 SENSING SYSTEM WITH AUXILIARY DISPLAY 审中-公开
公开(公告)号：US20100191086A1
公开(公告)日：2010-07-29
申请号：US12758379
申请日：2010-04-12
申请人： Cary D. Talbot , John J. Mastrototaro , Rajiv Shah , Edward Chernoff , John C. Mueller, JR. , Varaz Shahmirian , Richard E. Purvis , Wayne A. Morgan , Rebecca K. Gottlieb
发明人： Cary D. Talbot , John J. Mastrototaro , Rajiv Shah , Edward Chernoff , John C. Mueller, JR. , Varaz Shahmirian , Richard E. Purvis , Wayne A. Morgan , Rebecca K. Gottlieb
IPC分类号： A61B5/145
CPC分类号： A61B5/0002 , A61B5/145 , A61B5/14532 , A61B5/412 , A61B2560/0209 , A61B2560/0443 , A61B2560/0456
摘要： A system is provided for sensing blood glucose data of a patient. The system includes a sensor, user interface, and an optional auxiliary device. If the connection between the sensor and user interface is by a wire, the sensor remains powered when the wire is disconnected. The communication between the sensor and the user interface may be wireless. The auxiliary device can be a patient monitor or other display or signal device, which displays information about the blood glucose data collected by the sensor. The sensor is connected to sensor electronics, which include a sensor power supply, a voltage regulator, and optionally a memory and processor.

16. 发明授权

US07727148B2 Sensing system with auxiliary display 有权
标题翻译：带辅助显示屏的感应系统
公开(公告)号：US07727148B2
公开(公告)日：2010-06-01
申请号：US11980149
申请日：2007-10-30
申请人： Cary D. Talbot , John J. Mastrototaro , Rajiv Shah , Edward Chernoff , John C. Mueller, Jr. , Varaz Shahmirian , Richard E. Purvis , Wayne A. Morgan , Rebecca K. Gottlieb
发明人： Cary D. Talbot , John J. Mastrototaro , Rajiv Shah , Edward Chernoff , John C. Mueller, Jr. , Varaz Shahmirian , Richard E. Purvis , Wayne A. Morgan , Rebecca K. Gottlieb
IPC分类号： A61B5/00
CPC分类号： A61B5/0002 , A61B5/145 , A61B5/14532 , A61B5/412 , A61B2560/0209 , A61B2560/0443 , A61B2560/0456
摘要： A system is provided for sensing blood glucose data of a patient. The system includes a sensor, user interface, and an optional auxiliary device. If the connection between the sensor and user interface is by a wire, the sensor remains powered when the wire is disconnected. The communication between the sensor and the user interface may be wireless. The auxiliary device can be a patient monitor or other display or signal device, which displays information about the blood glucose data collected by the sensor. The sensor is connected to sensor electronics, which include a sensor power supply, a voltage regulator, and optionally a memory and processor.
摘要翻译：提供了一种用于感测患者血糖数据的系统。该系统包括传感器，用户界面和可选的辅助设备。如果传感器和用户界面之间的连接是通过导线连接的，那么当导线断开时，传感器保持供电。传感器和用户界面之间的通信可能是无线的。辅助装置可以是患者监视器或其他显示器或信号装置，其显示关于由传感器收集的血糖数据的信息。传感器连接到传感器电子设备，其中包括传感器电源，电压调节器以及可选的存储器和处理器。

17. 发明授权

US09309550B2 Analyte sensors having nanostructured electrodes and methods for making and using them 有权
标题翻译：具有纳米结构电极的分析物传感器及其制造和使用方法
公开(公告)号：US09309550B2
公开(公告)日：2016-04-12
申请号：US12361413
申请日：2009-01-28
申请人： Kenneth W. Cooper , Ratnakar Vejella , Gopikrishnan Soundararajan , Rajiv Shah
发明人： Kenneth W. Cooper , Ratnakar Vejella , Gopikrishnan Soundararajan , Rajiv Shah
IPC分类号： C12Q1/00 , A61B5/145 , A61B5/1486 , A61B5/00 , B82Y15/00 , B82Y30/00
CPC分类号： C12Q1/001 , A61B5/14532 , A61B5/14865 , A61B5/6846 , B82Y15/00 , B82Y30/00
摘要： Embodiments of the invention provide analyte sensors having nanostructured electrodes as well as methods for making and using such sensors. In certain embodiments of the invention, the sensor includes a carbon nanotube electrode and a analyte limiting membrane that modulates the ability of a analyte to contact the carbon nanotube electrode.
摘要翻译：本发明的实施例提供了具有纳米结构电极的分析物传感器以及用于制造和使用这种传感器的方法。在本发明的某些实施方案中，传感器包括碳纳米管电极和分析物限制膜，其调节分析物与碳纳米管电极接触的能力。

18. 发明申请

US20090198117A1 ANALYTE SENSORS HAVING NANOSTRUCTURED ELECTRODES AND METHODS FOR MAKING AND USING THEM 有权
标题翻译：具有纳米结构电极的分析仪传感器及其制造和使用方法
公开(公告)号：US20090198117A1
公开(公告)日：2009-08-06
申请号：US12361413
申请日：2009-01-28
申请人： Kenneth W. Cooper , Ratnakar Vejella , Gopikrishnan Soundararajan , Rajiv Shah
发明人： Kenneth W. Cooper , Ratnakar Vejella , Gopikrishnan Soundararajan , Rajiv Shah
IPC分类号： A61B5/1473 , C12Q1/54
CPC分类号： C12Q1/001 , A61B5/14532 , A61B5/14865 , A61B5/6846 , B82Y15/00 , B82Y30/00
摘要： Embodiments of the invention provide analyte sensors having nanostructured electrodes as well as methods for making and using such sensors. In certain embodiments of the invention, the sensor includes a carbon nanotube electrode and a analyte limiting membrane that modulates the ability of a analyte to contact the carbon nanotube electrode.
摘要翻译：本发明的实施例提供了具有纳米结构电极的分析物传感器以及用于制造和使用这种传感器的方法。在本发明的某些实施方案中，传感器包括碳纳米管电极和分析物限制膜，其调节分析物与碳纳米管电极接触的能力。

19. 发明申请

US20080156661A1 System and Method for Determining the Point of Hydration and Proper Time to Apply Potential to a Glucose Sensor 有权
标题翻译：用于确定水合点和适当时间以将葡萄糖传感器施加电位的系统和方法
公开(公告)号：US20080156661A1
公开(公告)日：2008-07-03
申请号：US11966294
申请日：2007-12-28
申请人： Kenneth W. Cooper , David Y. Choy , Rajiv Shah , Gopikrishnan Soundararajan , Ratnakar Vejella
发明人： Kenneth W. Cooper , David Y. Choy , Rajiv Shah , Gopikrishnan Soundararajan , Ratnakar Vejella
IPC分类号： G01N27/26
CPC分类号： A61B5/14532 , A61B5/14865 , A61B5/6848 , A61B5/6849 , A61B17/3468 , A61B2560/0223 , G01N27/3271
摘要： According to an embodiment of the invention, a method of determining hydration of a sensor having a plurality of electrodes is disclosed. In particular embodiments, the method couples a sensor electronics device to the sensor and measures the open circuit potential between at least two of the plurality of electrodes. Then, the open circuit potential measurement is compared to a predetermined value. In some embodiments, the plurality of electrodes includes a working electrode, a reference electrode, and a counter electrode. In still further embodiments, the open circuit potential between the working electrode and the reference electrode is measured. In other embodiments, the open circuit potential between the working electrode and the counter electrode is measured. In still other embodiments, the open circuit potential between the counter electrode and the reference electrode is measured.
摘要翻译：根据本发明的实施例，公开了一种确定具有多个电极的传感器的水化的方法。在具体实施例中，该方法将传感器电子设备耦合到传感器并且测量多个电极中的至少两个之间的开路电位。然后，将开路电位测量与预定值进行比较。在一些实施例中，多个电极包括工作电极，参考电极和对电极。在另外的实施例中，测量工作电极和参考电极之间的开路电位。在其他实施例中，测量工作电极和对电极之间的开路电位。在其他实施例中，测量对电极和参考电极之间的开路电位。

20. 发明授权

US07344500B2 Sensing system with auxiliary display 有权
标题翻译：带辅助显示屏的感应系统
公开(公告)号：US07344500B2
公开(公告)日：2008-03-18
申请号：US10899623
申请日：2004-07-27
申请人： Cary D. Talbot , John J. Mastrototaro , Rajiv Shah , Edward Chernoff , John C. Mueller, Jr. , Varaz Shahmirian , Richard E. Purvis , Wayne A. Morgan , Rebecca K. Gottlieb
发明人： Cary D. Talbot , John J. Mastrototaro , Rajiv Shah , Edward Chernoff , John C. Mueller, Jr. , Varaz Shahmirian , Richard E. Purvis , Wayne A. Morgan , Rebecca K. Gottlieb
IPC分类号： A61B5/00
CPC分类号： A61B5/0002 , A61B5/145 , A61B5/14532 , A61B5/412 , A61B2560/0209 , A61B2560/0443 , A61B2560/0456
摘要： A system is provided for sensing blood glucose data of a patient. The system includes a sensor, user interface, and an optional auxiliary device. If the connection between the sensor and user interface is by a wire, the sensor remains powered when the wire is disconnected. The communication between the sensor and the user interface may be wireless. The auxiliary device can be a patient monitor or other display or signal device, which displays information about the blood glucose data collected by the sensor. The sensor is connected to sensor electronics, which include a sensor power supply, a voltage regulator, and optionally a memory and processor.
摘要翻译：提供了一种用于感测患者血糖数据的系统。该系统包括传感器，用户界面和可选的辅助设备。如果传感器和用户界面之间的连接是通过导线连接的，那么当导线断开时，传感器保持供电。传感器和用户界面之间的通信可能是无线的。辅助装置可以是患者监视器或其他显示器或信号装置，其显示关于由传感器收集的血糖数据的信息。传感器连接到传感器电子设备，其中包括传感器电源，电压调节器以及可选的存储器和处理器。

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