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    • 12. 发明申请
    • MOUNTING MEANS FOR MOUNTING NATURAL STONE, AND METHOD OF MOUNTING NATURAL STONE
    • 安装自然石的安装方法,以及安装天然石的方法
    • US20110047916A1
    • 2011-03-03
    • US12936049
    • 2009-03-25
    • Martin Müller
    • Martin Müller
    • E04B2/18E04C2/04E04C2/30
    • E04F13/144E04F13/0819
    • Natural stone cladding (10) with a plurality of strips (18.1, 18.2) for surface-parallel mounting on a surface to be clad, with a number of natural stone elements (11.1, 11.2) and a number of support holders (30.1, 30.2) and counterholders (20.1, 20.2). Each natural stone element (11.1, 11.2) comprises a visible front side and a rear side with a first machine-made longitudinal recess and a second machine-made longitudinal recess. Pairs of support holders (30.1, 30.2) are fastened to adjacent strips (18.1, 18.2) and one natural stone element (11.1, 11.2) is seated by the first longitudinal recess on these two support holders (30.1, 30.2). One each of the two support holders (30.1, 30.2) is seated a respective counterholder (20.1, 20.2), and each of the two counterholders (20.1, 20.2) engages in the second longitudinal recess (15) in order to secure the natural stone element (11.1, 11.2).
    • 具有多个条带(18.1,18.2)的天然石材包层(10),用于表面平行地安装在要包层的表面上,具有许多天然石材元件(11.1,11.2)和多个支撑支架(30.1,30.2 )和柜台持有人(20.1,20.2)。 每个天然石材元件(11.1,11.2)包括可见的前侧和后侧,其具有第一机械纵向凹槽和第二机械制造的纵向凹槽。 一对支撑架(30.1,30.2)固定在相邻的条(18.1,18.2)上,一个天然石质元件(11.1,11.2)由第一纵向凹槽安置在这两个支撑支架(30.1,30.2)上。 两个支撑支架(30.1,30.2)中的每一个都位于相应的扶手(20.1,20.2)上,并且两个止推器(20.1,20.2)中的每一个接合在第二纵向凹槽(15)中,以便固定天然石材 元素(11.1,11.2)。
    • 13. 发明授权
    • Polyvalent vaccine against diseases caused by papilloma viruses, method for the production and the use thereof
    • 针对由乳头瘤病毒引起的疾病的多价疫苗,其生产方法及其用途
    • US07320861B2
    • 2008-01-22
    • US10485454
    • 2002-07-26
    • Lutz GissmannKai PohlmeyerMartin Müller
    • Lutz GissmannKai PohlmeyerMartin Müller
    • C12Q1/68
    • C07K16/084A61K39/12C12N2710/20034
    • A vaccine against disease caused by papilloma viruses is described in certain embodiments, as well as certain vectors, obtainable by the following methods: (a) one or more expression vectors that contain the DNA code for a structural protein of papilloma viruses or a fragment thereof are injected into mammals, whereby in at least some of the expression vectors randomly generated heterologous sequences are inserted into the DNA code (b) serums are obtained from the mammals and these are tested for the presence of antibodies against particles of various papilloma virus types, and (c) using the serums tested, the structural protein gene clones are identified that code for a polyvalent vaccine, and (d) the vaccine is produced from them. Procedures for producing a vaccine is also described, together with its use for vaccination against diseases caused by papilloma viruses.
    • 在某些实施方案中描述了针对由乳头瘤病毒引起的疾病的疫苗,以及可通过以下方法获得的某些载体:(a)含有乳头状瘤病毒或其片段的结构蛋白的DNA编码的一种或多种表达载体 注射到哺乳动物中,由此在至少一些表达载体中随机产生的异源序列插入到DNA代码(b)中,从哺乳动物获得血清,并测试这些血清是否存在针对各种乳头状瘤病毒类型的颗粒的抗体, 和(c)使用测试的血清,鉴定编码多价疫苗的结构蛋白质基因克隆,和(d)从它们产生疫苗。 还描述了生产疫苗的程序,以及其用于针对由乳头瘤病毒引起的疾病的疫苗接种的用途。
    • 15. 发明授权
    • Method of estimating residual exhaust gas concentration in a variable cam phase engine
    • 估计可变凸轮相位发动机中残余排气浓度的方法
    • US06550451B1
    • 2003-04-22
    • US10162375
    • 2002-06-04
    • Martin MüllerJeffrey M. Pfeiffer
    • Martin MüllerJeffrey M. Pfeiffer
    • F02P500
    • F02D41/0062F02D2041/001F02D2041/1433F02D2041/1437F02D2200/0411Y02T10/47
    • A method of estimating the concentration of residual exhaust gas in an internal combustion engine having variable cam phase control is based on engine dynamometer and engine simulator data. Since both the volumetric efficiency and the residual exhaust gas concentration of an engine vary monotonically in response to changes in cam phase, the simulated residual concentration data is deemed to be reliable if the simulated volumetric efficiency data matches volumetric efficiency data determined by engine dynamometer testing. Volumetric efficiency test data is compared to simulated volumetric efficiency data, and the simulation software is tuned until the simulated data matches the test data. At such point, the simulated residual concentration data is deemed to be reliable, and is used to calibrate a model relating residual concentration to cam phase angle, and such model is then used by an engine controller to estimate residual exhaust gas concentration during operation of the engine.
    • 在具有可变凸轮相位控制的内燃机中估计残余排气浓度的方法基于发动机测功机和发动机模拟器数据。 由于发动机的体积效率和残余废气浓度都是随着凸轮相位的变化而单调变化的,如果模拟的容积效率数据与发动机测功机测试确定的体积效率数据相匹配,则认为模拟残留浓度数据是可靠的。 将容积效率测试数据与模拟容积效率数据进行比较,并调整仿真软件,直到模拟数据与测试数据匹配。 在这种情况下,模拟残留浓度数据被认为是可靠的,并且用于校准与残余浓度相关的凸轮相位角度的模型,然后由发动机控制器使用该模型来估计操作期间的残余排气浓度 发动机。
    • 16. 发明授权
    • Engine torque management method with high dilution EGR control
    • 具有高稀释EGR控制的发动机转矩管理方法
    • US06367462B1
    • 2002-04-09
    • US09661229
    • 2000-09-13
    • Daniel Lee McKayGary Arthur NicholsMartin Müller
    • Daniel Lee McKayGary Arthur NicholsMartin Müller
    • F02B4708
    • F02D41/005F02B47/08F02D41/0072F02D2041/0017F02D2200/0408F02D2250/18Y02T10/47
    • An improved engine torque management control that coordinates engine throttle, spark and EGR under predefined highly throttled conditions so as to maximize the fuel economy improvement of EGR without degrading engine performance. Under the predefined conditions, EGR is increased to a level that maximizes the fuel economy improvement without causing combustion instability, and the throttle position and spark timing are controlled to compensate for the anticipated torque loss while increasing volumetric efficiency and reducing pumping losses. During idle and steady state cruising operation, EGR is increased, and engine throttle position is controlled to regulate the estimated engine output torque in accordance with the driver requested output torque. During transient torque increases, throttle control alone is used to regulate the output torque, while in transient torque decreases, the throttle position is maintained and spark timing is used to regulate the output torque.
    • 改进的发动机扭矩管理控制,其在预定义的高节流条件下协调发动机节气门,火花和EGR,以便最大化EGR的燃料经济性改进,而不降低发动机性能。 在预定条件下,EGR增加到使燃油经济性改善最大化而不引起燃烧不稳定的水平,并且控制节气门位置和火花正时以补偿预期的扭矩损失,同时增加容积效率并减少泵送损失。 在空转和稳态巡航操作期间,EGR增加,并且控制发动机节气门位置以根据驾驶员请求的输出转矩来调节估计的发动机输出转矩。 在瞬时扭矩增加期间,单独使用节气门控制来调节输出转矩,而在瞬时扭矩减小时,节气门位置得以保持,并且使用火花正时来调节输出转矩。
    • 20. 发明申请
    • GENOTYPING OF BOVINE PAPILLOMAVIRUS GENOTYPES
    • 牛血清病毒基因组遗传学研究
    • US20120107797A1
    • 2012-05-03
    • US13256930
    • 2010-03-17
    • Markus SchmittMartin Müller
    • Markus SchmittMartin Müller
    • C12Q1/70
    • C12Q1/708
    • The present invention is concerned with the provision of diagnostic means and methods. Specifically, it relates to a composition comprising oligonucleotides selected from at least two different groups of oligonucleotides, said groups comprising at least one pair of oligonucleotides being capable of specifically amplifying polynucleotides comprised by a Bovine Papillomavirus (BPV), said BPV being selected from the group consisting of BPV-1, BPV-2, BPV-3, BPV-4, BPV-5, BPV-6, BPV-7, BPV-8, BPV-9, BPV-10, and BAPV-11 as well as uses based on said composition and kits comprising it. Moreover, contemplated is a method for the simultaneous detection and/or identification of BPV types in a sample.
    • 本发明涉及提供诊断手段和方法。 具体地,本发明涉及包含寡核苷酸的组合物,所述寡核苷酸选自至少两个不同的寡核苷酸组,所述组包含至少一对能够特异性扩增由牛乳头瘤病毒(BPV)组成的多核苷酸的寡核苷酸,所述BPV选自组 由BPV-1,BPV-2,BPV-3,BPV-4,BPV-5,BPV-6,BPV-7,BPV-8,BPV-9,BPV-10和BAPV-11组成, 基于所述组合物和包含它的试剂盒。 此外,预期的是同时检测和/或识别样品中BPV类型的方法。