专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明授权

US07981656B2 Pseudotyped retrovirus with modified ebola glycoprotein 失效
标题翻译：具有修饰的埃博拉糖蛋白的假型逆转录病毒
公开(公告)号：US07981656B2
公开(公告)日：2011-07-19
申请号：US10516578
申请日：2003-06-04
申请人： David A. Sanders , Scott A. Jeffers , Anthony Sanchez
发明人： David A. Sanders , Scott A. Jeffers , Anthony Sanchez
IPC分类号： C12N7/00 , C07H21/02
CPC分类号： C12N15/86 , A61K35/13 , C12N2740/15043 , C12N2740/15045 , C12N2760/14122 , C12N2810/60 , C12N2810/6072 , Y10S977/802 , Y10S977/803
摘要： Pseudotyped retroviruses having viral glycoproteins with modified O glycosylation regions are provided. Also provided are methods for making the pseudotyped retroviruses of the present invention and for using the pseudotyped retroviruses for transduction of target cells. Cells for stably producing the pseudotyped retroviruses or the present invention are also provided.
摘要翻译：提供具有修饰的O糖基化区域的具有病毒糖蛋白的假型逆转录病毒。还提供了制备本发明的假型逆转录病毒和使用假型逆转录病毒用于转导靶细胞的方法。还提供了用于稳定产生假型逆转录病毒或本发明的细胞。

12. 发明申请

US20110096490A1 Peripheral Device Carrying Apparatus and Systems 有权
标题翻译：外围设备携带设备和系统
公开(公告)号：US20110096490A1
公开(公告)日：2011-04-28
申请号：US12604801
申请日：2009-10-23
申请人： Anthony Sanchez , Stephen James Wotherspoon , Steven J. Zielnicki , David M. Ajo
发明人： Anthony Sanchez , Stephen James Wotherspoon , Steven J. Zielnicki , David M. Ajo
IPC分类号： G06F1/16 , A47B81/00
CPC分类号： G06F1/187
摘要： A peripheral device assembly is disclosed wherein the assembly includes a device bay for receiving a peripheral device carrier. An interior side surface of the device bay defines at least one extrusion portion surrounding a hole for receiving a first end of a lever arm of the peripheral device carrier, and the extrusion portion comprises edges protruding from the interior side surface of the device bay toward an exterior side surface of the device bay.
摘要翻译：公开了一种外围设备组件，其中组件包括用于接收外围设备载体的设备间隔。装置隔间的内侧表面限定围绕孔的至少一个挤压部分，用于接收外围装置载体的杠杆臂的第一端，并且挤压部分包括从装置隔室的内侧表面向着设备托架的外侧面。

13. 发明申请

US20110058328A1 HARD DRIVE RAIL FOR HARD DRIVE CARRIER 有权
标题翻译：用于硬盘驱动器的硬盘驱动器
公开(公告)号：US20110058328A1
公开(公告)日：2011-03-10
申请号：US12554266
申请日：2009-09-04
申请人： David M. Ajo , Anthony Sanchez , David W. Williams
发明人： David M. Ajo , Anthony Sanchez , David W. Williams
IPC分类号： G06F1/16
CPC分类号： G06F1/187 , Y10T29/49155
摘要： A rail apparatus includes first plate formed of a synthetic material having a first face and a second face opposite the first face, the first plate having a plurality of rows of spaced apart rail protrusions in a first pattern protruding from the second face of the first plate. A second metal plate includes a first face and a second face opposite the first face, the second plate having a plurality of rows of spaced apart slots in a second pattern matching the first pattern and extending through the first and second faces of the second plate. The second face of the first plate abutting the second face of the second plate, whereby the rows of rail protrusions extend through the slots and extend from the first face of the second plate.
摘要翻译：轨道装置包括由具有第一面和与第一面相对的第二面的合成材料形成的第一板，第一板具有从第一板的第二面突出的第一图案中的多排间隔开的轨道突起。第二金属板包括第一面和与第一面相对的第二面，第二板具有多列间隔开的狭槽，第二图案与第一图案匹配，并延伸穿过第二板的第一和第二面。第一板的第二面邻接第二板的第二面，由此，这些轨道突起延伸穿过槽并从第二板的第一面延伸。

14. 发明申请

US20100303857A1 DEVELOPMENT OF A PREVENTIVE VACCINE FOR FILOVIRUS INFECTION IN PRIMATES 有权
公开(公告)号：US20100303857A1
公开(公告)日：2010-12-02
申请号：US12612625
申请日：2009-11-04
申请人： Gary J. Nabel , Zhi-yong Yang , Nancy Sullivan , Anthony Sanchez
发明人： Gary J. Nabel , Zhi-yong Yang , Nancy Sullivan , Anthony Sanchez
IPC分类号： A61K39/12 , A61P31/14
CPC分类号： C07K14/005 , A61K39/12 , A61K2039/5256 , A61K2039/53 , A61K2039/545 , A61K2039/55522 , A61K2039/70 , C12N2710/10343 , C12N2760/14122 , C12N2760/14134 , C12N2760/14222
摘要： The present invention relates generally to viral vaccines and, more specifically, to filovirus vaccines and methods of eliciting an immune response against a filovirus or disease caused by infection with filovirus.

15. 发明申请

US20100298414A1 DEVELOPMENT OF A PREVENTIVE VACCINE FOR FILOVIRUS INFECTION IN PRIMATES 有权
标题翻译：用于预防FIV病毒感染的预防性疫苗的开发
公开(公告)号：US20100298414A1
公开(公告)日：2010-11-25
申请号：US12612621
申请日：2009-11-04
申请人： Gary J. Nabel , Zhi-yong Yang , Nancy Sullivan , Anthony Sanchez
发明人： Gary J. Nabel , Zhi-yong Yang , Nancy Sullivan , Anthony Sanchez
IPC分类号： A61K31/7088 , A61P37/04
CPC分类号： C07K14/005 , A61K39/12 , A61K2039/5256 , A61K2039/53 , A61K2039/545 , A61K2039/55522 , A61K2039/70 , C12N2710/10343 , C12N2760/14122 , C12N2760/14134 , C12N2760/14222
摘要： The present invention relates generally to viral vaccines and, more specifically, to filovirus vaccines and methods of eliciting an immune response against a filovirus or disease caused by infection with filovirus.
摘要翻译：本发明一般涉及病毒疫苗，更具体地涉及针对由病毒感染引起的病毒或疾病引起免疫应答的病毒疫苗和方法。

16. 发明申请

US20070087008A1 Rab9a, rab11a, and modulators thereof related to infectious disease 审中-公开
标题翻译： Rab9a，rab11a及其与传染病相关的调节剂
公开(公告)号：US20070087008A1
公开(公告)日：2007-04-19
申请号：US10590844
申请日：2005-02-24
申请人： Thomas Hodge , Natalie McDonald , Donald Rubin , Michaewl Shaw , Anthony Sanchez , James Murray
发明人： Thomas Hodge , Natalie McDonald , Donald Rubin , Michaewl Shaw , Anthony Sanchez , James Murray
IPC分类号： A01K67/00 , G01N33/53 , A61K48/00 , A61K39/40
CPC分类号： C07K14/82 , A01K2217/075 , A01K2267/0337 , A61K48/00 , C12N15/113 , C12N15/1135 , C12N15/1138 , C12N2310/11 , C12N2310/121 , C12N2310/14 , G01N33/569 , G01N33/56983 , G01N2500/00 , G01N2800/26 , Y02A50/52
摘要： Disclosed herein are methods of reducing infection of a cell by a pathogen, for example to treat or prevent a pathogen infection. Exemplary pathogens include those that use a lipid raft. The disclosure also relates to methods of identifying agents involved in pathogen infection, such as modulators of Rab9A and Rab11A.
摘要翻译：本文公开的是减少病原体感染细胞的方法，例如治疗或预防病原体感染。示例性病原体包括使用脂筏的病原体。本公开还涉及鉴定参与病原体感染的药剂的方法，例如Rab9A和Rab11A的调节剂。

17. 发明授权

US08124592B2 Development of a preventive vaccine for filovirus infection in primates 有权
公开(公告)号：US08124592B2
公开(公告)日：2012-02-28
申请号：US12612625
申请日：2009-11-04
申请人： Gary J. Nabel , Zhi-yong Yang , Nancy Sullivan , Anthony Sanchez
发明人： Gary J. Nabel , Zhi-yong Yang , Nancy Sullivan , Anthony Sanchez
IPC分类号： A61K31/70 , A61K49/00 , A01N65/00 , C12N5/00 , C12N15/00 , C07H21/02
CPC分类号： C07K14/005 , A61K39/12 , A61K2039/5256 , A61K2039/53 , A61K2039/545 , A61K2039/55522 , A61K2039/70 , C12N2710/10343 , C12N2760/14122 , C12N2760/14134 , C12N2760/14222
摘要： The present invention relates generally to viral vaccines and, more specifically, to filovirus vaccines and methods of eliciting an immune response against a filovirus or disease caused by infection with filovirus.

18. 发明申请

US20110189193A1 CELL LINES AND HOST NUCLEIC ACID SEQUENCES RELATED TO INFECTIOUS DISEASE 审中-公开
标题翻译：细胞系和宿主细胞核酸序列与感染性疾病相关
公开(公告)号：US20110189193A1
公开(公告)日：2011-08-04
申请号：US13045020
申请日：2011-03-10
申请人： Thomas W. Hodge , Natalie J. McDonald , Michael W. Shaw , Donald H. Rubin , Anthony Sanchez
发明人： Thomas W. Hodge , Natalie J. McDonald , Michael W. Shaw , Donald H. Rubin , Anthony Sanchez
IPC分类号： A61K39/395 , C12N5/07 , G01N33/53 , A61K31/7088 , A61K31/7105 , A61K31/713 , C12Q1/70 , C12Q1/68 , A61P31/18 , A61P31/16 , A61P31/14
CPC分类号： C07K14/47 , C12N15/113 , C12N15/1138 , C12N2310/14 , C12Q1/18 , G01N33/56983 , G01N2500/02
摘要： Host nucleic acids and host proteins that participate in viral infection, such as human immunodeficiency virus (HIV), influenza A, and Ebola virus, have been identified. Interfering with or disrupting the interaction between a host nucleic acid or host protein and a virus or viral protein confers an inhibition of or resistance to infection. Thus, interfering with such an interaction in a host subject can confer a therapeutic or prophylactic effect against a virus. The sequences identified can be used to identify agents that reduce or inhibit viral infection.
摘要翻译：已经鉴定了参与病毒感染的宿主核酸和宿主蛋白，例如人类免疫缺陷病毒（HIV），甲型流感和埃博拉病毒。干扰或破坏宿主核酸或宿主蛋白与病毒或病毒蛋白质之间的相互作用赋予对感染的抑制或抗性。因此，干扰宿主受试者中的这种相互作用可以赋予针对病毒的治疗或预防效果。鉴定的序列可用于鉴定减少或抑制病毒感染的试剂。

19. 发明授权

US07948747B2 Hard drive rail for hard drive carrier 有权
标题翻译：用于硬盘驱动器托盘的硬盘驱动器
公开(公告)号：US07948747B2
公开(公告)日：2011-05-24
申请号：US12554266
申请日：2009-09-04
申请人： David M. Ajo , Anthony Sanchez , David W. Williams
发明人： David M. Ajo , Anthony Sanchez , David W. Williams
IPC分类号： G06F1/16
CPC分类号： G06F1/187 , Y10T29/49155
摘要： A rail apparatus includes first plate formed of a synthetic material having a first face and a second face opposite the first face, the first plate having a plurality of rows of spaced apart rail protrusions in a first pattern protruding from the second face of the first plate. A second metal plate includes a first face and a second face opposite the first face, the second plate having a plurality of rows of spaced apart slots in a second pattern matching the first pattern and extending through the first and second faces of the second plate. The second face of the first plate abutting the second face of the second plate, whereby the rows of rail protrusions extend through the slots and extend from the first face of the second plate.
摘要翻译：轨道装置包括由具有第一面和与第一面相对的第二面的合成材料形成的第一板，第一板具有从第一板的第二面突出的第一图案中的多排间隔开的轨道突起。第二金属板包括第一面和与第一面相对的第二面，第二板具有多列间隔开的狭槽，第二图案与第一图案匹配，并延伸穿过第二板的第一和第二面。第一板的第二面邻接第二板的第二面，由此，这些轨道突起延伸穿过槽并从第二板的第一面延伸。

20. 发明授权

US07927793B2 Cell lines and host nucleic acid sequences related to infectious disease 有权
标题翻译：与感染性疾病相关的细胞系和宿主核酸序列
公开(公告)号：US07927793B2
公开(公告)日：2011-04-19
申请号：US10535523
申请日：2003-11-18
申请人： Thomas W. Hodge , Natalie J. McDonald , Michael W. Shaw , Donald H. Rubin , Anthony Sanchez
发明人： Thomas W. Hodge , Natalie J. McDonald , Michael W. Shaw , Donald H. Rubin , Anthony Sanchez
IPC分类号： C12Q1/68 , C12P21/06
CPC分类号： C07K14/47 , C12N15/113 , C12N15/1138 , C12N2310/14 , C12Q1/18 , G01N33/56983 , G01N2500/02
摘要： Host nucleic acids and host proteins that participate in viral infection, such as human immunodeficiency virus (HIV), influenza A, and Ebola virus, have been identified. Interfering with or disrupting the interaction between a host nucleic acid or host protein and a virus or viral protein confers an inhibition of or resistance to infection. Thus, interfering with such an interaction in a host subject can confer a therapeutic or prophylactic effect against a virus. The sequences identified can be used to identify agents that reduce or inhibit viral infection.
摘要翻译：已经鉴定了参与病毒感染的宿主核酸和宿主蛋白，例如人类免疫缺陷病毒（HIV），甲型流感和埃博拉病毒。干扰或破坏宿主核酸或宿主蛋白与病毒或病毒蛋白质之间的相互作用赋予对感染的抑制或抗性。因此，干扰宿主受试者中的这种相互作用可以赋予针对病毒的治疗或预防效果。鉴定的序列可用于鉴定减少或抑制病毒感染的试剂。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式