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11. 发明授权

US08259222B2 Portable multi position magnifier camera 有权
公开(公告)号：US08259222B2
公开(公告)日：2012-09-04
申请号：US12235182
申请日：2008-09-22
申请人： Carlos M. Rodriguez , Patrick Murphy , Waldemar Tunkis , Brad Davis , Todd Conard , Lee Hamilton , Michael Goldenberg , Jeffrey McDaniel
发明人： Carlos M. Rodriguez , Patrick Murphy , Waldemar Tunkis , Brad Davis , Todd Conard , Lee Hamilton , Michael Goldenberg , Jeffrey McDaniel
IPC分类号： H04N5/225
CPC分类号： H04N5/2252 , H04N1/195 , H04N1/19594 , H04N5/2256 , H04N2201/043 , H04N2201/0436 , H04N2201/045
摘要： Disclosed is a portable magnifier camera that can be selectively positioned into a variety of configurations. At least four distinct viewing configurations are provided: a reading mode wherein the camera rests flatly upon the viewed object; a writing mode wherein the camera rests at an angle upon the viewed object; a hand-held mode wherein the user holds the camera relative to a distant object; and an inspection mode wherein the user holds the viewed object relative to the camera. These configurations enable a user to effectively view objects of differing size and at varying distances.

12. 发明授权

US08264598B2 Multiposition handheld electronic magnifier 有权
标题翻译：多功能手持电子放大镜
公开(公告)号：US08264598B2
公开(公告)日：2012-09-11
申请号：US12478993
申请日：2009-06-05
申请人： Carlos M. Rodriguez , Patrick Murphy , Waldemar Tunkis , Todd Conard , Michael Goldenberg , Jeffrey McDaniel
发明人： Carlos M. Rodriguez , Patrick Murphy , Waldemar Tunkis , Todd Conard , Michael Goldenberg , Jeffrey McDaniel
IPC分类号： H04N5/225
CPC分类号： H04N5/23293 , G03B17/563 , H04N1/00129 , H04N5/2252 , H04N5/23296 , H04N5/2628 , H04N9/64 , H04N2101/00
摘要： Disclosed is a magnifier for use by blind or low vision users. The magnifier includes a camera, such as a CMOS image sensor, that displays enlarged images upon a screen for easy viewing. The magnifier further includes a handle that is pivotally interconnected to a housing to allow for handheld use in a variety of different configurations.
摘要翻译：公开了一种用于盲人或低视力用户使用的放大镜。放大镜包括诸如CMOS图像传感器的相机，其在屏幕上显示放大的图像以便于观看。放大镜还包括手柄，该手柄枢转地互连到壳体以允许以各种不同构造的手持使用。

13. 发明申请

US20100026854A1 Portable Multi Position Magnifier Camera 有权
标题翻译：便携式多功能放大镜相机
公开(公告)号：US20100026854A1
公开(公告)日：2010-02-04
申请号：US12235182
申请日：2008-09-22
申请人： Carlos M. Rodriguez , Patrick Murphy , Waldemar Tunkis , Brad Davis , Todd Conard , Lee Hamilton , Michael Goldenberg , Jeffrey McDaniel
发明人： Carlos M. Rodriguez , Patrick Murphy , Waldemar Tunkis , Brad Davis , Todd Conard , Lee Hamilton , Michael Goldenberg , Jeffrey McDaniel
IPC分类号： H04N5/262 , H04N5/225
CPC分类号： H04N5/2252 , H04N1/195 , H04N1/19594 , H04N5/2256 , H04N2201/043 , H04N2201/0436 , H04N2201/045
摘要： Disclosed is a portable magnifier camera that can be selectively positioned into a variety of configurations. At least four distinct viewing configurations are provided: a reading mode wherein the camera rests flatly upon the viewed object; a writing mode wherein the camera rests at an angle upon the viewed object; a hand-held mode wherein the user holds the camera relative to a distant object; and an inspection mode wherein the user holds the viewed object relative to the camera. These configurations enable a user to effectively view objects of differing size and at varying distances.
摘要翻译：公开了一种可以选择性地定位成各种配置的便携式放大镜照相机。提供至少四个不同的观察构造：读取模式，其中相机平坦地搁置在所观看的对象上; 一种写入模式，其中相机以一定的角度搁置在所观看的对象上; 手持模式，其中用户相对于遥远的物体保持照相机; 以及其中用户相对于相机保持所观看对象的检查模式。这些配置使用户能够有效地查看不同大小和不同距离的物体。

14. 外观设计

USD662121S1 Portable magnifier camera 有权
标题翻译：便携式放大镜相机
公开(公告)号：USD662121S1
公开(公告)日：2012-06-19
申请号：US29386933
申请日：2011-03-07
申请人： Carlos M. Rodriguez , Michael Goldenberg , Lee Hamilton , Bradley S. Davis
设计人： Carlos M. Rodriguez , Michael Goldenberg , Lee Hamilton , Bradley S. Davis

15. 发明授权

US6104512A Method for adjusting the power level of an infrared signal 失效
标题翻译：调整红外信号功率电平的方法
公开(公告)号：US6104512A
公开(公告)日：2000-08-15
申请号：US12444
申请日：1998-01-23
申请人： Charles E. Batey, Jr. , Carlos M. Rodriguez , John B. Van Zile
发明人： Charles E. Batey, Jr. , Carlos M. Rodriguez , John B. Van Zile
IPC分类号： H04B10/114 , H04B10/00
CPC分类号： H04B10/1143
摘要： An electronic device (50) includes an infrared transceiver (510) having adjustable infrared signal intensity capability. The electronic device (50) commences to establish communications with a secondary device (420 and/or 430) at a first power level, if the communication link is not established, the electronic device (50) increases the IR power level and tries again to establish communications. In an alternate embodiment, the electronic device (50) includes a power level table which keeps the power level which has been established for each secondary device (420, 430) using the method described above. The electronic device (50) before communicating with each of the secondary devices determines the proper power level to use depending on the secondary device (420, 430) it wants to communicate with. In still a further embodiment, instead of determining the power level to use at the start of the communications, an ongoing exchange of signal quality information is sent between the communicating devices in order to adjust the power level of the devices during the communication session.
摘要翻译：电子设备（50）包括具有可调节的红外信号强度能力的红外收发器（510）。电子设备（50）开始以第一功率电平建立与辅助设备（420和/或430）的通信，如果通信链路未建立，则电子设备（50）增加IR功率电平并再次尝试建立沟通。在替代实施例中，电子设备（50）包括功率电平表，其使用上述方法保持已经为每个辅助设备（420,430）建立的功率电平。在与每个次级装置通信之前的电子装置（50）根据其想要通信的辅助装置（420,430）确定要使用的适当功率电平。在又一实施例中，代替确定在通信开始时使用的功率电平，在通信设备之间发送信号质量信息的持续交换，以便在通信会话期间调整设备的功率电平。

16. 发明授权

US5492833A Reticulocyte analyzing method and apparatus utilizing light scatter techniques 失效
标题翻译：利用光散射技术的网织红细胞分析方法和装置
公开(公告)号：US5492833A
公开(公告)日：1996-02-20
申请号：US306346
申请日：1994-09-15
申请人： Carlos M. Rodriguez , Stephen L. Ledis
发明人： Carlos M. Rodriguez , Stephen L. Ledis
IPC分类号： G01N33/48 , G01N15/10 , G01N15/14 , G01N33/49
CPC分类号： G01N15/1459 , G01N15/12 , G01N2015/1006 , G01N2015/1037 , G01N2021/4704 , G01N2021/4716 , G01N33/49 , Y10T436/25125
摘要： A reticulocyte analyzing method and apparatus in which a biological sample stream of ghosted red cells is passed into and through a point focused beam of light, such as laser light. A light detector structure is positioned with respect to the axis of the light beam to provide a light output pulse indicative of the passage of each cell. Electrically conductive contacts within the fluid stream can provide additional electrical pulse outputs of each cell. A staining reagent can be utilized with a ghosting reagent to further differentiate the reticulocytes. The light and the light and electronic produced output pulses or signals can be combined to define and quantify reticulocytes as distinct from other known cell types.
摘要翻译：一种网织红细胞分析方法和装置，其中将重影的红细胞的生物样品流传入并通过诸如激光的点聚焦光束。光检测器结构相对于光束的轴线定位，以提供指示每个单元通过的光输出脉冲。流体流内的导电触点可以提供每个电池的附加电脉冲输出。染色试剂可与重影试剂一起使用以进一步区分网织红细胞。光和光和电子产生的输出脉冲或信号可以组合以限定和定量网织红细胞，与其他已知的细胞类型不同。

17. 发明授权

US5231005A Method and apparatus for screening cells or formed bodies with populations expressing selected characteristics 失效
标题翻译：用于筛选具有选择特征的群体的细胞或成体的方法和装置
公开(公告)号：US5231005A
公开(公告)日：1993-07-27
申请号：US849481
申请日：1992-03-10
申请人： Thomas Russell , Kenneth H. Kortright , Wallace H. Coulter , Carlos M. Rodriguez , Ronald Paul , Constance M. Hajek , James C. Hudson
发明人： Thomas Russell , Kenneth H. Kortright , Wallace H. Coulter , Carlos M. Rodriguez , Ronald Paul , Constance M. Hajek , James C. Hudson
IPC分类号： G01N15/00 , G01N15/10 , G01N15/12 , G01N15/14 , G01N33/50 , G01N33/53 , G01N33/543 , G01N33/569 , G01N35/00
CPC分类号： G01N15/12 , G01N33/5002 , G01N33/5094 , G01N33/5302 , G01N33/54326 , G01N33/56972 , G01N15/14 , G01N2015/008 , G01N2015/1037 , G01N2015/1062 , G01N2015/1081 , G01N35/0098 , Y10T436/101666 , Y10T436/117497 , Y10T436/24
摘要： A method and apparatus for automatically and rapidly, retrieving, counting and/or analyzing at least one selected population of cells or formed bodies, such as a white blood cell population and at least one subset thereof of a whole blood sample or portion thereof. A volume of a biological medium containing the white blood cells is prepared and at least one reactant specific or preferential at least to some selected biological cells is introduced thereto and rapidly mixed for a short period of time. The opacity and/or volume parameter of the cells can be modified and the mixture is then counted and analyzed in one or more steps to obtain the desired white blood cell population and subset analysis. The biological sample can be a whole blood sample and the reactant can include or be a lyse or a monoclonal antibody bound to microspheres, which will bind to specific ones of the cells or a combination of lyse and microspheres with antibody bound thereto. The microspheres can be magnetic and the bound cells can be magnetically removed for retrieving and analyzing the remaining blood cell population.
摘要翻译：一种用于自动并快速地检索，计数和/或分析全血样本或其部分的至少一个选定细胞群体或形成体，例如白细胞群体及其至少一个子集的方法和装置。制备含有白细胞的体积的生物培养基，并将至少一种至少一种选择的生物细胞特异性或优先选择的反应物引入其中并在短时间内快速混合。可以修改细胞的不透明度和/或体积参数，然后在一个或多个步骤中对混合物进行计数和分析，以获得所需的白细胞群体和子集分析。生物样品可以是全血样品，并且反应物可以包括结合微球的裂解液或单克隆抗体，其将与特定细胞结合，或与结合抗体的溶血和微球体的组合。微球可以是磁性的，并且结合的细胞可被磁性去除，用于检索和分析剩余的血细胞群体。

18. 发明授权

US4791355A Particle analyzer for measuring the resistance and reactance of a particle 失效
标题翻译：用于测量颗粒的电阻和电抗的粒子分析仪
公开(公告)号：US4791355A
公开(公告)日：1988-12-13
申请号：US921654
申请日：1986-10-21
申请人： Wallace H. Coulter , Carlos M. Rodriguez
发明人： Wallace H. Coulter , Carlos M. Rodriguez
IPC分类号： G01N15/12 , G01N33/48 , G01N27/00
CPC分类号： G01N15/1227 , G01N2015/129
摘要： A circuit, which is useful to provide data needed to measure the electrical opacity of a particle, for instance a blood cell, passing through a Coulter type transducer, includes a current source for providing a conventional d.c. current through the sensing aperture of the transducer, as well as an oscillator for providing a high frequency current through the aperture. The oscillator includes an active device and a resonant circuit, and the aperture is coupled in parallel with the resonant circuit of the oscillator. The oscillator can be any type of oscillator, such as a Hartley oscillator. As a particle passes through the aperture, the resistance of the aperture increases, which in turn, increases the Q of the oscillator circuit, whereby the oscillator output signal is amplitude modulated in accordance with the increased Q. This amplitude modulated signal can be detected to provide a value based on the high frequency reactance of the particle being detected. The change in d.c. resistance due to a particle passing through the aperture is detected in a conventional manner. The detected amplitudes of the a.c. and d.c. signals then can be compared to determine the opacity of each particle. Multiple oscillators of different frequencies can be coupled in parallel with the transducer through a coupling circuit, which connects each oscillator to the transducer through a low impedance path and isolates each oscillator from signals having frequencies of the other oscillators.
摘要翻译：用于提供测量通过Coulter型换能器的颗粒（例如血细胞）的电气不透明度所需的数据的电路包括用于提供常规直流电流的电流源。通过传感器的感测孔径的电流，以及用于提供通过孔径的高频电流的振荡器。振荡器包括有源器件和谐振电路，并且该孔与振荡器的谐振电路并联耦合。振荡器可以是任何类型的振荡器，例如Hartley振荡器。当颗粒通过孔径时，孔径的电阻增加，这又增加了振荡器电路的Q，由此根据增加的Q对振荡器输出信号进行幅度调制。该幅度调制信号可以被检测为提供基于所检测的粒子的高频电抗的值。 d.c.的变化以常规方式检测通过孔径的颗粒的电阻。检测到的a.c.的振幅。和d.c. 然后可以比较信号来确定每个粒子的不透明度。不同频率的多个振荡器可以通过耦合电路与传感器并联耦合，该耦合电路通过低阻抗路径将每个振荡器连接到换能器，并将每个振荡器与具有其他振荡器频率的信号隔离开来。

19. 发明授权

US4535284A High and low frequency analysis of osmotic stress of cells 失效
标题翻译：细胞渗透胁迫的高低频分析
公开(公告)号：US4535284A
公开(公告)日：1985-08-13
申请号：US282293
申请日：1981-07-10
申请人： Michael R. Groves , Carlos M. Rodriguez
发明人： Michael R. Groves , Carlos M. Rodriguez
IPC分类号： G01N15/12 , G01N33/487 , G01N33/49 , G01N27/00
CPC分类号： G01N15/12
摘要： Disclosed is a method wherein osmotic activity of biological cells immersed in a suspension solution is induced by an osmotic or lytic shock and is monitored in an electronic volume sensing particle analyzer of the Coulter Counter.RTM. type, the method including the steps of passing a high frequency current and a low frequency current through an aperture of said particle analyzer to create detectable signals for classifying the cells into populations of unaltered, altered, and ghost cells.
摘要翻译：公开了一种方法，其中浸入悬浮溶液中的生物细胞的渗透活性是由渗透或溶解性休克引起的，并在Coulter Counter TM型的电子体积感测粒子分析仪中进行监测，该方法包括以下步骤：电流和低频电流通过所述粒子分析仪的孔径产生可检测的信号，以将细胞分类为未改变的，改变的和重影细胞的群体。

20. 发明授权

US06579685B1 Method and apparatus for screening microscopic cells utilizing light scatter techniques 失效
标题翻译：使用光散射技术筛选显微细胞的方法和装置
公开(公告)号：US06579685B1
公开(公告)日：2003-06-17
申请号：US08303924
申请日：1994-09-09
申请人： Thomas Russell , James Carey Hudson , Wallace H. Coulter , Carlos M. Rodriguez , Constance Mary Hajek
发明人： Thomas Russell , James Carey Hudson , Wallace H. Coulter , Carlos M. Rodriguez , Constance Mary Hajek
IPC分类号： G01N3353
CPC分类号： G01N33/56972 , Y10S435/808 , Y10S435/962 , Y10S436/805 , Y10S436/824 , Y10S436/825
摘要： A method for performing screening of one or more cell groups of interest obscured by a cell population such as one or more subsets of interest of a WBC population utilizing at least one light sensing parameter. The cell group of interest is enumerated by utilizing microspheres having monoclonal antibodies bound thereto to modify the sensed characteristics of specified cells to differentiate the cell group of interest from the obscuring cell population.
摘要翻译：利用至少一个光感测参数，用于进行筛选感兴趣的一个或多个感兴趣的细胞群的方法被细胞群体例如WBC群体的一个或多个感兴趣的亚群遮蔽。通过利用与其结合的具有单克隆抗体的微球来修饰感兴趣的特定细胞的特征以区分感兴趣的细胞群和模糊细胞群体，来计算感兴趣的细胞群。

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