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11. 发明申请

WO2009140291A3 CONTINUOUS FIELD TOMOGRAPHY SYSTEMS AND METHODS OF USING THE SAME 审中-公开
标题翻译：连续的田间计量系统及其使用方法
公开(公告)号：WO2009140291A3
公开(公告)日：2010-02-25
申请号：PCT/US2009043653
申请日：2009-05-12
申请人： PROTEUS BIOMEDICAL INC , ARNE LAWRENCE , BANOS ORLANDO , BEHZADI YASHAR , COLLIOU OLIVIER , COSTELLO BENEDICT , LEICHNER ROBERT , MOON GREGORY , ROBERTSON TIMOTHY , SAVAGE GEORGE , THOMPSON TODD , ZDEBLICK MARK
发明人： ARNE LAWRENCE , BANOS ORLANDO , BEHZADI YASHAR , COLLIOU OLIVIER , COSTELLO BENEDICT , LEICHNER ROBERT , MOON GREGORY , ROBERTSON TIMOTHY , SAVAGE GEORGE , THOMPSON TODD , ZDEBLICK MARK
IPC分类号： A61B5/0402 , A61B5/0408
CPC分类号： A61B5/046 , A61B5/0006 , A61B5/0031 , A61B5/0422 , A61B5/0536 , A61B5/0538 , A61B5/4519 , A61B5/743 , A61B5/7435 , A61B6/503 , A61B8/0883
摘要： Continuous field tomography systems are provided. Aspects of systems include a data aggregating module configured to receive both continuous field tomography data and non-continuous field physiological data and produce an aggregated data product from these disparate types of data. Also provided are methods of using systems of the invention in a variety of different applications, including diagnostic and therapeutic applications. The systems and methods of the invention find use in a variety of different applications, such as cardiac related applications.
摘要翻译：提供连续场断层摄影系统。系统的方面包括数据聚合模块，其配置为接收连续场断层摄影数据和非连续场生理数据，并从这些不同类型的数据产生聚合数据产物。还提供了在各种不同应用中使用本发明的系统的方法，包括诊断和治疗应用。本发明的系统和方法可用于各种不同的应用，例如心脏相关应用。

12. 发明申请

WO2012015756A3 HYBRID HOUSING FOR IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：可植入医疗器械的混合住房
公开(公告)号：WO2012015756A3
公开(公告)日：2012-05-31
申请号：PCT/US2011045227
申请日：2011-07-25
申请人： PROTEUS BIOMEDICAL INC , ARNE LAWRENCE , JENSEN MARC , THOMPSON TODD
发明人： ARNE LAWRENCE , JENSEN MARC , THOMPSON TODD
IPC分类号： A61L27/10 , A61L27/04 , B65D13/02
CPC分类号： H05K5/069 , A61L27/04 , A61L27/10 , A61N1/37205 , A61N1/3756 , H05K13/00 , Y10T29/49002
摘要： Apparatuses and methods for hybrid housings as well as hybrid housing based implantable medical devices are provided. A hybrid housing comprises a ceramic substrate, a bonding structure formed on the periphery of the ceramic substrate, and a biocompatible metal cap coupled to the ceramic substrate using the bonding structure to form a hermetically sealed enclosure. One or more electronic elements may be formed within the hermetically sealed enclosure, and the electronic elements may be stably associated with the ceramic substrate.
摘要翻译：提供了混合外壳的装置和方法以及基于混合外壳的可植入医疗装置。混合外壳包括陶瓷基板，形成在陶瓷基板的周边上的接合结构以及使用该接合结构形成密封外壳的与陶瓷基板结合的生物相容性金属盖。一个或多个电子元件可以形成在密封的外壳内，并且电子元件可以稳定地与陶瓷基板相关联。

13. 发明申请

WO2012149466A2 BODY ASSOCIATED DEVICE AND METHOD OF MAKING SAME 审中-公开
标题翻译：身体相关装置及其制造方法
公开(公告)号：WO2012149466A2
公开(公告)日：2012-11-01
申请号：PCT/US2012035650
申请日：2012-04-27
申请人： PROTEUS BIOMEDICAL INC , ARNE LAWRENCE , HUTCHISON JAMES
发明人： ARNE LAWRENCE , HUTCHISON JAMES
IPC分类号： A61B5/0402 , A61B5/0408 , A61B5/0424
CPC分类号： A61B5/6833 , A61B5/04087 , A61B5/04284 , A61B5/681 , A61B5/6831 , A61B2560/0443 , A61B2562/0214 , A61B2562/125 , A61B2562/164
摘要： Methods of manufacturing a body associated device are disclosed. The methods include providing an inlay substrate comprising a first side, a second side, and at least one conductive trace and providing an interposer substrate comprising a first side, a second side, and at least one conductive trace. An electrically conductive layer is applied to the first side of the inlay substrate. The at least one conductive trace is electrically coupled to the conductive layer. The first side of the interposer substrate is coupled to the first side of the inlay substrate to form a subassembly. The at least one conductive trace on the interposer substrate is electrically coupled to the at least one conductive trace on the inlay substrate through the electrically conductive layer. A body associated device with a wet electrode manufactured in accordance with a first process is disclosed. A body associated device with a dry electrode manufactured in accordance with a second process is disclosed.
摘要翻译：公开了制造身体相关装置的方法。所述方法包括提供包含第一侧，第二侧和至少一个导电迹线的镶嵌衬底，并提供包括第一侧，第二侧和至少一个导电迹线的插入物衬底。将导电层施加到嵌体衬底的第一侧。所述至少一个导电迹线电耦合到所述导电层。插入器衬底的第一侧耦合到嵌入衬底的第一侧以形成子组件。插入器衬底上的至少一个导电迹线通过导电层电耦合到嵌入衬底上的至少一个导电迹线。公开了一种根据第一种方法制造的具有湿电极的本体关联装置。公开了一种具有根据第二工艺制造的干电极的本体关联装置。

14. 发明申请

WO2010045385A3 METHOD AND SYSTEM FOR INCORPORATING PHYSIOLOGIC DATA IN A GAMING ENVIRONMENT 审中-公开
标题翻译：在游戏环境中包含生理数据的方法和系统
公开(公告)号：WO2010045385A3
公开(公告)日：2010-07-22
申请号：PCT/US2009060713
申请日：2009-10-14
申请人： PROTEUS BIOMEDICAL INC , THOMPSON ANDREW , SAVAGE GEORGE , KARPLUS ERIKA , ARNE LAWRENCE , ROBERTSON TIMOTHY , O'REILLY DAVID
发明人： THOMPSON ANDREW , SAVAGE GEORGE , KARPLUS ERIKA , ARNE LAWRENCE , ROBERTSON TIMOTHY , O'REILLY DAVID
IPC分类号： G06Q50/00
CPC分类号： A63F13/23 , A61B5/02055 , A61B5/02405 , A61B5/073 , A61B5/0816 , A61B5/4833 , A63F13/02 , A63F13/212 , A63F2300/1012 , A63F2300/6045 , G06Q50/00 , G07F17/32 , G07F17/3206 , G07F17/3237
摘要： The present invention provides a receiving device and method for use with gaming pursuits, including, in one aspect, a personal signal receiver to communicate physiologic data, a hub to receive the physiologic data, and a gaming module to receive, directly or indirectly, the physiologic data from the hub.
摘要翻译：本发明提供了一种用于与游戏活动一起使用的接收设备和方法，在一个方面，其包括传送生理数据的个人信号接收器，接收生理数据的集线器以及直接或间接接收来自枢纽的生理数据。

15. 发明申请

WO2011146767A3 TRACKING AND DELIVERY CONFIRMATION OF PHARMACEUTICAL PRODUCTS 审中-公开
标题翻译：跟踪和交付药物产品的确认
公开(公告)号：WO2011146767A3
公开(公告)日：2012-03-15
申请号：PCT/US2011037236
申请日：2011-05-19
申请人： PROTEUS BIOMEDICAL INC , THOMPSON TODD , ARNE LAWRENCE , OMIDVAR FATANEH , BEHZADI YASHAR , DUCK ROBERT , DICARLO LORENZO , MOON GREGORY
发明人： THOMPSON TODD , ARNE LAWRENCE , OMIDVAR FATANEH , BEHZADI YASHAR , DUCK ROBERT , DICARLO LORENZO , MOON GREGORY
IPC分类号： G06F19/00 , G06F15/16
CPC分类号： G06Q50/22 , A61M3/00 , G06F19/3462 , G06F19/3468 , G08C15/06 , H04N7/18
摘要： A system and method are disclosed that track a deliverable to a user. The system includes an identifier or tag secured to the deliverable, a computer system for interrogating the identifier, and a personal device in communication with the computer system, wherein the personal device is held by the user at the time the user is administered the deliverable to detect the unique identity associated with the identifier device and confirms delivery of the deliverable to the user. The method includes attaching an identifiable tag that produces a unique signature to the deliverable, interrogating the tag at about the time of delivery to the user, and confirming that the user has been administered the deliverable through detecting the identifiable tag.
摘要翻译：公开了一种跟踪可交付给用户的系统和方法。系统包括固定到可交付物的标识符或标签，用于询问标识符的计算机系统以及与计算机系统通信的个人设备，其中在用户被管理可交付物时，个人设备由用户持有检测与标识符设备相关联的唯一身份，并确认可交付物品的传送给用户。该方法包括将产生唯一签名的可识别标签附加到可交付物，在大约递送给用户的时间询问标签，并通过检测可识别标签来确认用户已经对可交付物进行了管理。

16. 发明申请

WO2008063626A3 ACTIVE SIGNAL PROCESSING PERSONAL HEALTH SIGNAL RECEIVERS 审中-公开
标题翻译：主动信号处理个人健康信号接收器
公开(公告)号：WO2008063626A3
公开(公告)日：2008-07-03
申请号：PCT/US2007024225
申请日：2007-11-19
申请人： PROTEUS BIOMEDICAL INC , ARNE LAWRENCE , AU-YEUNG KITYEE , CRANDELL KENNETH C , ROBERTSON TIMOTHY
发明人： ARNE LAWRENCE , AU-YEUNG KITYEE , CRANDELL KENNETH C , ROBERTSON TIMOTHY
IPC分类号： A61N1/08
CPC分类号： H04B1/1027 , A61B5/0028 , A61B5/0031 , A61B5/7257 , A61B2560/0209 , H04B1/123 , H04B13/005 , H04L1/0036 , H04L1/0045 , H04L27/152 , H04L27/22 , H04L27/2271 , H04L27/2273
摘要： The invention provides a receiver associated with a body, e.g., located inside or within close proximity to a body, configured to receive and decode a signal from an in vivo transmitter which located inside the body. Signal receivers of the invention provide for accurate signal decoding of a low-level signal, even in the presence of significant noise, using a small-scale chip, e.g., where the chip consumes very low power. Also provided are systems that include the receivers, as well as methods of using the same.
摘要翻译：本发明提供一种与身体相关联的接收器，例如位于身体内部或紧邻身体，被配置为接收和解码来自位于体内的体内发射器的信号。本发明的信号接收机即使在存在显着噪声的情况下也能使用小尺寸芯片（例如芯片消耗非常低的功率）来提供对低电平信号的精确信号解码。还提供了包括接收器的系统，以及使用它们的方法。

17. 发明专利

JP2012157747A Implantable integrated circuit 审中-公开
标题翻译：可嵌入式集成电路
公开(公告)号：JP2012157747A
公开(公告)日：2012-08-23
申请号：JP2012120680
申请日：2012-05-28
申请人： Proteus Biomedical Inc , プロテウスバイオメディカルインコーポレイテッド
发明人： ZDEBLICK MARK , LEICHNER ROBERT , ARIA BEHARD , JANI NILAY , LI HAIFENG , THOMPSON TODD , ARNE LAWRENCE , ROBERTSON TIMOTHY , BI YAFEI , GELFANDBEIN VLADIMIER
IPC分类号： A61N1/372 , A61N1/368
CPC分类号： A61N1/056 , A61B5/0422 , A61N1/025 , A61N1/362 , A61N1/3686 , A61N1/372 , A61N1/37205 , A61N1/37276 , A61N1/37288 , A61N1/3756
摘要： PROBLEM TO BE SOLVED: To provide robust, reliable control functionality for an effector present on intraluminal, e.g., vascular, leads, as well as other types of implantable devices.SOLUTION: Embodiments of the invention enable the required functionality for accurate long term control of effectors units, even ones present on multiplex carrier configurations, while provide for low power consumption. Aspects of the invention include implantable integrated circuits that have power extraction; energy storage; communication; and device configuration functional blocks, where these functional blocks are all present in a single integrated circuit on an intraluminal-sized support. Also provided by the invention are effector assemblies that include the integrated circuits, as well as implantable medical devices, e.g., pulse generators that include the same, as well as systems and kits thereof and methods of using the same, e.g., in pacing applications, including cardiac resynchronization therapy (CRT) applications.
摘要翻译：要解决的问题：为管腔内（例如血管，引线以及其他类型的可植入装置）上的效应器提供鲁棒，可靠的控制功能。解决方案：本发明的实施例能够实现对效应器单元的准确的长期控制所需的功能，即使存在于多路载波配置上的效果器单元也能提供低功率消耗。本发明的方面包括具有功率提取的可植入集成电路; 储能; 通讯; 以及器件配置功能块，其中这些功能块都存在于腔内尺寸支持体上的单个集成电路中。本发明还提供了包括集成电路的效应器组件以及可植入的医疗装置，例如包括其的脉冲发生器，以及其系统和套件，以及使用该装置的方法，例如在起搏应用中，包括心脏再同步治疗（CRT）应用。版权所有（C）2012，JPO＆INPIT

18. 发明专利

AU2009268827A1 Ingestible event marker data framework 未知
公开(公告)号：AU2009268827A1
公开(公告)日：2010-01-14
申请号：AU2009268827
申请日：2009-07-02
申请人： PROTEUS BIOMEDICAL INC
发明人： THOMPSON ANDREW , KARPLUS ERIKA , ROBERTSON TIMOTHY , BEHZADI YASHAR , ARNE LAWRENCE , BEAULIEU PATRICK , ZDEBLICK MARK , O'REILLY DAVID , SAVAGE GEORGE , MOON GREGORY
IPC分类号： A61B5/06 , G05F1/00 , G16H10/60 , H04B13/00
摘要： The ingestible event marker data framework provides a uniform, comprehensive framework to enable various functions and utilities related to ingestible event marker data (IEM data). The functions and utilities include data and / or information having an aspect of data derived from, collected by, aggregated by, or otherwise associated with, an ingestion event.

19. 发明专利

SG172846A1 INGESTION-RELATED BIOFEEDBACK AND PERSONALIZED MEDICAL THERAPY METHOD AND SYSTEM 未知
公开(公告)号：SG172846A1
公开(公告)日：2011-08-29
申请号：SG2011048899
申请日：2010-01-06
申请人： PROTEUS BIOMEDICAL INC
发明人： JENSEN MARC , LEICHNER ROBERT , BEAULIEU PATRICK , AU-YEUNG KIT YEE , ARNE LAWRENCE , ZDEBLICK MARK , THOMPSON ANDREW , SAVAGE GEORGE , ROBERTSON TIMOTHY , BEHZADI YASHAR
IPC分类号： A61B5/375
摘要： Methods, devices and systems for acquiring information useful to support a patient in implementing and adhering to a medically prescribed therapy plan are provided. The therapy may incorporate biofeedback methods and/or personalized therapy aspects. A method includes steps of receiving, by a receiving device, biometric information associated with an ingestible event marker; analyzing, by a computing device having a microprocessor configured to perform a biometric information analysis, the biometric information; and determining a therapeutic recommendation at least partly on the basis of the analysis and/or integrating biofeedback techniques into patient therapy or activity. A system includes a biometric information module to receive biometric information associated with an ingestible event marker; an analysis module to analyze the biometric information; and a determination module to optionally determine and communicate a therapeutic recommendation at least partly on the basis of the analysis.

20. 发明公开

EP1968693A4 IMPLANTABLE INTEGRATED CIRCUIT 审中-公开
标题翻译：植入集成电路
公开(公告)号：EP1968693A4
公开(公告)日：2011-04-27
申请号：EP06847996
申请日：2006-12-22
申请人： PROTEUS BIOMEDICAL INC
发明人： ZDEBLICK MARK , LEICHNER ROBERT , ARIA BEHARD , JANI NILAY , LI HAIFENG , THOMPSON TODD , ARNE LAWRENCE , ROBERTSON TIMOTHY , BI YAFEI , GELFANDBEIN VLADIMIER
IPC分类号： A61B5/04
CPC分类号： A61N1/056 , A61B5/0422 , A61N1/025 , A61N1/362 , A61N1/3686 , A61N1/372 , A61N1/37205 , A61N1/37276 , A61N1/37288 , A61N1/3756

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