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11. 发明申请

WO2007037986A2 CREATION OF OPTIMIZED TERRAIN DATABASES 审中-公开
标题翻译：创建最佳地形数据库
公开(公告)号：WO2007037986A2
公开(公告)日：2007-04-05
申请号：PCT/US2006/035669
申请日：2006-09-14
申请人： THE BOEING COMPANY , SCHIEFELE, Jens , LAUNER, Marc , HOUK, Richard , FOX, Michael
发明人： SCHIEFELE, Jens , LAUNER, Marc , HOUK, Richard , FOX, Michael
CPC分类号： G01C7/04 , G01C3/20 , G01C21/32 , Y10S707/918 , Y10S707/919 , Y10S707/92
摘要： Systems and methods for generating an optimized terrain database identify several regions, including test regions that are established from the identified regions. A first set of terrain data is received for a first test region. The first set of terrain data is compared to a second set of terrain data to determine a set of quality attributes. The quality attributes are used to determine a safety margin for the first test region. The safety margin is applied to other regions having the same or similar characteristics to the first test region. Safety margins are either generated for or applied to all other regions. All regions are then compiled into an area- wide terrain database, up to and including a worldwide database.
摘要翻译：用于生成优化的地形数据库的系统和方法识别若干个区域，包括从所识别的区域建立的测试区域。第一组地形数据被接收用于第一测试区域。将第一组地形数据与第二组地形数据进行比较以确定一组质量属性。质量属性用于确定第一个测试区域的安全裕度。安全余量应用于具有与第一测试区域相同或相似特性的其他区域。为所有其他地区生成或应用安全边际。然后将所有区域编译成一个区域范围内的地形数据库，直至并包括全球数据库。

12. 发明申请

WO2003057151A3 A STABLE PHARMACEUTICAL FORMULATION OF PAROXETINE HYDROCHLORIDE ANHYDROUS AND A PROCESS FOR PREPARATION THEREOF 审中-公开
公开(公告)号：WO2003057151A3
公开(公告)日：2003-07-17
申请号：PCT/US2002/041430
申请日：2002-12-27
申请人： TEVA PHARMACEUTICAL INDUSTRIES LTD. , TEVA PHARMACEUTICALS USA, INC. , FOX, Michael , COHEN, Rakefet , BRAUNSTEIN, Anne , LEIBOVICI, Minutza
发明人： FOX, Michael , COHEN, Rakefet , BRAUNSTEIN, Anne , LEIBOVICI, Minutza
IPC分类号： A61K9/14
摘要： Provided are formulations of a stable commercial paroxetine tablet comprising paroxetine hydrochloride anhydrous, povidone, copovidone or HPMC as a binder, and an HCI free/non-hygroscopic filler, prepared by the wet granulation method.

13. 发明申请

WO2003057151A2 A STABLE PHARMACEUTICAL FORMULATION OF PAROXETINE HYDROCHLORIDE ANHYDROUS AND A PROCESS FOR PREPARATION THEREOF 审中-公开
标题翻译：一种稳定的药物制备方法及其制备方法
公开(公告)号：WO2003057151A2
公开(公告)日：2003-07-17
申请号：PCT/US2002/041430
申请日：2002-12-27
申请人： TEVA PHARMACEUTICAL INDUSTRIES LTD. , TEVA PHARMACEUTICALS USA, INC. , FOX, Michael , COHEN, Rakefet , BRAUNSTEIN, Anne , LEIBOVICI, Minutza
发明人： FOX, Michael , COHEN, Rakefet , BRAUNSTEIN, Anne , LEIBOVICI, Minutza
IPC分类号： A61K
CPC分类号： A61K9/2886 , A61K9/2009 , A61K9/2027 , A61K9/2054 , A61K9/2059 , A61K9/2077 , A61K9/2095 , A61K9/2866 , A61K31/4525
摘要： Provided are formulations of a stable commercial paroxetine tablet comprising paroxetine hydrochloride anhydrous, povidone, copovidone or HPMC as a binder, and an HCI free/non-hygroscopic filler, prepared by the wet granulation method.
摘要翻译：提供了一种稳定的商业帕罗西汀片剂的制剂，其包含无水盐酸帕罗西汀，聚维酮，共聚维酮或HPMC作为粘合剂，以及通过湿法制粒法制备的无HCl /非吸湿性填料。

14. 发明申请

WO2017130196A1 AUTONOMOUSLY OPERATING COMPUTERIZED GAMING PLATFORMS AND METHOD OF OPERATING THEREOF 审中-公开
标题翻译：自动运行的计算机化游戏平台及其操作方法
公开(公告)号：WO2017130196A1
公开(公告)日：2017-08-03
申请号：PCT/IL2017/050095
申请日：2017-01-25
申请人： PLAYTECH SOFTWARE LIMITED , FOX, Michael , RAM, Ethan
发明人： FOX, Michael , RAM, Ethan
IPC分类号： G06F9/54 , G07F17/32 , A63F13/49
CPC分类号： G07F17/32 , G06F9/541
摘要： A method of operating a first computerized gaming platform comprising: enabling data communication between the first computerized gaming platform and a second computerized gaming platform with the help of an inter-platform wagering module (WM), the first and second computerized gaming platforms operating autonomously one of the other; obtaining data indicative of a player ID associated with a given player and forwarding the data indicative of a player ID to the second gaming platform; requesting from the second gaming platform the most updated player-related data corresponding to the player ID and obtaining the player-related data; and executing by the first gaming platform one or more game-related campaigns for the given player in accordance with the obtained player-related data.
摘要翻译：一种操作第一计算机化游戏平台的方法，包括：在平台间投注模块（WM）的帮助下，实现所述第一计算机化游戏平台与第二计算机化游戏平台之间的数据通信，所述第一计算机化游戏平台和第二计算机化游戏平台，其自主操作另一个; 获得指示与给定玩家相关联的玩家ID的数据，并将指示玩家ID的数据转发给第二游戏平台; 向第二游戏平台请求与玩家ID对应的最新玩家相关数据并获得玩家相关数据; 以及由第一游戏平台根据所获得的玩家相关数据为给定玩家执行一个或多个游戏相关活动。

15. 发明申请

WO2008134013A2 PHARMACEUTICAL EXCIPIENT COMPLEX 审中-公开
标题翻译：药物特异性复合物
公开(公告)号：WO2008134013A2
公开(公告)日：2008-11-06
申请号：PCT/US2008/005386
申请日：2008-04-25
申请人： TEVA PHARMACEUTICAL INDUSTRIES LTD. , TEVA PHARMACEUTICALS USA, INC. , KANARI, Itamar , FOX, Michael , LEIBOVICI, Minutza
发明人： KANARI, Itamar , FOX, Michael , LEIBOVICI, Minutza
IPC分类号： A61K9/16 , A61K47/26 , A61K47/10 , A61K47/44
CPC分类号： A61K9/2018 , A61K9/1623 , A61K9/1641 , A61K9/1652 , A61K9/2027 , A61K9/2059
摘要： The present invention encompasses pharmaceutical excipient complexes comprising combining at least one carrier with an oily substance, and processes for preparing the same, stable pharmaceutical compositions comprising such complexes and active pharmaceutical ingredients and processes for preparing the same.
摘要翻译：本发明包括药物赋形剂复合物，其包括将至少一种载体与油性物质组合，及其制备方法，包含该配合物的稳定药物组合物和活性药物成分及其制备方法。

16. 发明申请

WO2008027532A3 PHARMACEUTICAL COMPOSITIONS INCLUDING VITAMIN D AND CORTICOSTEROID 审中-公开
公开(公告)号：WO2008027532A3
公开(公告)日：2008-03-06
申请号：PCT/US2007/019164
申请日：2007-08-29
申请人： TEVA PHARMACEUTICAL INDUSTRIES LTD. , TEVA PHARMACEUTICALS USA, INC. , COHEN, Rakefet , FOX, Michael
发明人： COHEN, Rakefet , FOX, Michael
IPC分类号： A61K9/06 , A61K45/06
摘要： Provided are pharmaceutical compositions comprising at least one vitamin D-containing compound, at least one corticosteroid compound, and at least one solvent component selected from the group consisting of triglycerides, sorbitan, sorbitan fatty esters, cetearyl glucoside, PEG-n sorbitan stearate, acrylamide/sodium acryloyldimethyl taurate copolymers, and mixtures thereof. Also provided are methods of making such compositions, and methods for treating psoriasis using such compositions.

17. 发明申请

WO2021263058A1 HER-2 TARGETED BISPECIFIC COMPOSITIONS AND METHODS FOR MAKING AND USING THE SAME 审中-公开
公开(公告)号：WO2021263058A1
公开(公告)日：2021-12-30
申请号：PCT/US2021/039006
申请日：2021-06-24
申请人： AMUNIX PHARMACEUTICALS, INC. , SCHELLENBERGER, Volker , JOHANSEN, Eric , HENKENSIEFKEN, Angela , MACCANN, Darragh , MCCLORY, James , KUHN, Phillipp , FRENZEL, Andre , TO, Milton , FOX, Michael , IRVING, Bryan , DERYNCK, Mika
发明人： SCHELLENBERGER, Volker , JOHANSEN, Eric , HENKENSIEFKEN, Angela , MACCANN, Darragh , MCCLORY, James , KUHN, Phillipp , FRENZEL, Andre , TO, Milton , FOX, Michael , IRVING, Bryan , DERYNCK, Mika
IPC分类号： C07K14/00 , A61K49/00 , A61K38/17 , C07K16/28 , A61K39/395
摘要： Disclosed herein are polypeptides, and methods of making and using such polypeptides, that comprise a bispecific antibody construct covalently linked to an extended recombinant polypeptide comprising a barcode fragment releasable from said polypeptide upon digestion by a protease, and a Release Segment that can be proteolytically cleaved wherein said cleavage releases the bispecifie antibody construct from the extended recombinant polypeptide.

18. 发明申请

WO2017019806A2 COLLAGEN XIX, FORMULATIONS THEREOF, AND METHODS OF TREATING NEURON SYNAPSE RELATED DISORDERS 审中-公开
标题翻译：胶原蛋白XIX，其制剂以及治疗神经元突触相关病症的方法
公开(公告)号：WO2017019806A2
公开(公告)日：2017-02-02
申请号：PCT/US2016/044334
申请日：2016-07-27
申请人： FOX, Michael , SU, Jianmin
发明人： FOX, Michael , SU, Jianmin
IPC分类号： A61K38/39
CPC分类号： A61K38/39 , C07K14/78
摘要： Provided herein are collagen XlX-based compositions and formulations thereof. Also provided herein are methods of inducing nerve terminal formation that can include the step of contacting a neuron with a collagen XlX-based compositions and formulations thereof provided herein. Also provided herein are methods of treating a nerve terminal formation disease or symptom thereof that can include the step of administering an amount of a collagen XlX-based composition or formulation thereof to a subject in need thereof.
摘要翻译：本文提供基于胶原蛋白X1X的组合物及其制剂。本文还提供了诱导神经末端形成的方法，其可以包括使神经元与本文提供的基于胶原蛋白X1X的组合物及其制剂接触的步骤。本文还提供治疗神经末梢形成疾病或其症状的方法，其可包括将一定量的基于胶原蛋白X1X的组合物或其制剂给予有需要的受试者的步骤。

19. 发明申请

WO2009025859A1 PALIPERIDONE SUSTAINED RELEASE FORMULATION 审中-公开
标题翻译： PALIPERIDONE持续释放配方
公开(公告)号：WO2009025859A1
公开(公告)日：2009-02-26
申请号：PCT/US2008/010014
申请日：2008-08-21
申请人： TEVA PHARMACEUTICAL INDUSTRIES LTD. , TEVA PHARMACEUTICALS USA, INC. , FOX, Michael , DI CAPUA, Simona , REINBERG, Ronny
发明人： FOX, Michael , DI CAPUA, Simona , REINBERG, Ronny
IPC分类号： A61K9/16 , A61K9/20 , A61K9/50
CPC分类号： A61K9/209 , A61K9/1676 , A61K9/2054 , A61K9/2072 , A61K9/2081 , A61K9/2086 , A61K9/5047 , A61K9/5073 , A61K9/5078 , A61K9/5084 , A61K31/506
摘要： The present invention provides sustained release dosage forms comprising Paliperidone and processes for preparing the same.
摘要翻译：本发明提供包含哌啶酮的缓释剂型及其制备方法。

20. 发明申请

WO2008109170A1 PHARMACEUTICAL COMPOSITION COMPRISING CANDESARTAN CILEXETIL 审中-公开
标题翻译：包含CANDESARTAN CILEXETIL的药物组合物
公开(公告)号：WO2008109170A1
公开(公告)日：2008-09-12
申请号：PCT/US2008/003169
申请日：2008-03-10
申请人： TEVA PHARMACEUTICAL INDUSTRIES LTD. , TEVA PHARMACEUTICALS USA, INC. , LEIBOVICI, Minutza , KANARI, Itamar , FOX, Michael
发明人： LEIBOVICI, Minutza , KANARI, Itamar , FOX, Michael
IPC分类号： A61K9/20
CPC分类号： A61K9/2013 , A61K9/2018 , A61K31/4184
摘要： The present invention encompasses pharmaceutical compositions comprising candesartan cilexetil, an amino acid and a pharmaceutically acceptable excipient, and processes for preparing the same.
摘要翻译：本发明包括药物组合物，其包含坎地沙坦碳酸酯，氨基酸和药学上可接受的赋形剂，及其制备方法。

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