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11. 发明申请

WO2017066255A1 GLUCOAMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME 审中-公开
标题翻译：葡糖淀粉酶变体和编码多核苷酸的多核苷酸
公开(公告)号：WO2017066255A1
公开(公告)日：2017-04-20
申请号：PCT/US2016/056549
申请日：2016-10-12
申请人： NOVOZYMES A/S , NELSON, Beth
发明人： NELSON, Beth , SVENDSEN, Allan , SRIVASTAVA, Vivek , MALTEN, Marco , POULSEN, Thomas A. , RAMAIYA, Preethi , GUPTA, Shikha , RAO, Vasudeva P. , BALUMURI, Padmavathi
IPC分类号： C12P19/02 , C12P19/20 , C12N9/34
CPC分类号： C12N9/2428 , C12P19/02 , C12P19/14 , C12P19/20 , C12Y302/01003
摘要： The present invention relates to glucoamylase variants having an increase in specific activity and/or an increase in melting temperature measured by TSA of at least 0.5 degrees Celsius, and further wherein the variants have at least at least 85%, at least 90%, at least 95% identity, at least 96%, at least 97%, at least 98%, or at least 99%, but less than 100%, sequence identity to the amino acid sequence of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
摘要翻译：本发明涉及葡糖淀粉酶变体，其通过TSA测量的比活性增加和/或熔解温度增加至少0.5摄氏度，并且另外其中变体具有至少85 与SEQ ID NO：1的氨基酸序列具有至少90％，至少90％，至少95％同一性，至少96％，至少97％，至少98％，或至少99％，但小于100％编号：3。本发明还涉及编码变体的多核苷酸; 包含所述多核苷酸的核酸构建体，载体和宿主细胞; 以及使用这些变体的方法。

12. 发明申请

WO2017005816A1 LIPASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME 审中-公开
标题翻译：脂肪变体和编码其的多核苷酸
公开(公告)号：WO2017005816A1
公开(公告)日：2017-01-12
申请号：PCT/EP2016/066035
申请日：2016-07-06
申请人： NOVOZYMES A/S
发明人： SAIKIA, Rakhi , MENDEZ, Geetha, Hiremath , DALAL, Sohel , BALUMURI, Padmavathi , MEPADAM, Santhosh, Vasu , BAUNSGAARD, Lone , VIND, Jesper , GIPPERT, Garry, Paul , BORCH, Kim
IPC分类号： C12N9/20 , C12N15/00 , C11D3/386
CPC分类号： C11D3/38627 , C11D3/38681 , C12N9/20
摘要： The present invention relates to a lipase variant of a parent lipase, which variant has lipase activity, at least 75% but less than 100% sequence identity to SEQ ID NO: 3 and comprises a substitution at one or more positions corresponding to positions 1; 2; 3; 4; 5; 6; 7; 9; 10; 11; 12; 13; 14; 15; 17; 18; 29; 30; 33; 34; 36; 37; 38; 40; 41; 43; 44; 45; 46; 47; 49; 50; 5 51; 52; 54; 55; 57; 58; 59; 60; 69; 70; 71; 72; 81; 82; 85; 86; 87; 89; 90; 91; 92; 94; 95; 96; 97; 99; 100; 101; 102; 103; 105; 108; 111; 115; 116; 118; 119; 120; 122; 123; 124; 126; 127; 128; 129; 130; 131; 132; 133; 134; 136; 144; 152; 155; 157; 158; 159; 161; 162; 163; 177; 178; 181; 182; 184; 185; 187; 189; 191; 196; 197; 199; 203; 205; 206; 207; 208; 209; 211; 215; 220; 221; 222; 223; 224; 226; 229; 230; 232; 235; 236; 240; 242; 243; 244; 247; 248; 252; 254; 255; 257; 10 260; 261; 262 of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
摘要翻译：本发明涉及母体脂肪酶的脂肪酶变体，该变体具有脂肪酶活性，与SEQ ID NO：3具有至少75％但小于100％的序列同一性，并且包含在对应于位置1的一个或多个位置的取代; 2; 3; 4; 5; 6; 7; 9; 10; 11; 12; 13; 14; 15; 17; 18; 29; 30; 33; 34; 36; 37; 38; 40; 41; 43; 44; 45; 46; 47; 49; 50; 5 51; 52; 54; 55; 57; 58; 59; 60; 69; 70; 71; 72; 81; 82; 85; 86; 87; 89; 90; 91; 92; 94; 95; 96; 97; 99; 100; 101; 102; 103; 105; 108; 111; 115; 116; 118; 119; 120; 122; 123; 124; 126; 127; 128; 129; 130; 131; 132; 133; 134; 136; 144; 152; 155; 157; 158; 159; 161; 162; 163; 177; 178; 181; 182; 184; 185; 187; 189; 191; 196; 197; 199; 203; 205; 206; 207; 208; 209; 211; 215; 220; 221; 222; 223; 224; 226; 229; 230; 232; 235; 236; 240; 242; 243; 244; 247; 248; 252; 254; 255; 257; 10 260; 261; 262。本发明还涉及编码变体的多核苷酸; 核酸构建体，载体和包含多核苷酸的宿主细胞; 以及使用这些变体的方法。

13. 发明申请

WO2016180749A1 ALPHA-AMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME 审中-公开
标题翻译： ALPHA-AMYLASE变体和编码它们的多核苷酸
公开(公告)号：WO2016180749A1
公开(公告)日：2016-11-17
申请号：PCT/EP2016/060267
申请日：2016-05-09
申请人： NOVOZYMES A/S
发明人： ANDERSEN, Carsten , SRIVASTAVA, Vivek , BALUMURI, Padmavathi , CHAKRABARTI, Partha, Pratim , DALAL, Sohel
IPC分类号： C12N9/28
CPC分类号： C12N9/2417 , C11D3/386 , C11D3/38681 , C12Y302/01001
摘要： The present invention relates to alpha-amylase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
摘要翻译：本发明涉及α-淀粉酶变体。本发明还涉及编码这些变体的多核苷酸; 核酸构建体，载体和包含多核苷酸的宿主细胞; 以及使用这些变体的方法。

14. 发明申请

WO2015181119A3 LIPASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME 审中-公开
标题翻译：脂肪酶变体和编码相同的多核苷酸
公开(公告)号：WO2015181119A3
公开(公告)日：2015-12-03
申请号：PCT/EP2015/061509
申请日：2015-05-26
申请人： NOVOZYMES A/S
发明人： BALUMURI, Padmavathi , SAIKIA, Rakhi , SVENDSEN, Allan , BAUNSGAARD, Lone
IPC分类号： C12P7/64 , C12N9/20
摘要： The present invention relates to a lipase variant of a parent lipase, which variant has lipase activity, at least 75% but less than 100% sequence identity to SEQ ID NO: 3 and comprises a substitution at one or more positions corresponding to positions 1; 2; 3; 4; 5; 6; 7; 9; 10; 11; 12; 16; 19; 30; 31; 34; 36; 37; 39; 40; 42; 44; 51; 52; 53; 54; 56; 58; 59; 70; 71; 72; 73; 83; 84; 86; 88; 90; 92; 93; 95; 96; 100; 101; 102; 104; 106; 109; 110; 112; 117; 119; 124; 125; 127; 128; 131; 132; 133; 134; 135; 137; 158; 159; 160; 161; 162; 163; 165; 166; 167; 168; 170; 181; 182; 183; 189; 190; 192; 194; 196; 202; 210; 211; 212; 220; 225; 227; 228; 229; 230; 231; 233; 237; 238; 239; 240; 242; 246; 247; 248; 252; 259; 262; 264; 269 of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
摘要翻译：本发明涉及亲本脂肪酶的脂肪酶变体，所述变体具有脂肪酶活性，与SEQ ID NO：3具有至少75％但小于100％的序列同一性，并且在一个或更多对应于位置1的位置; 2; 3; 4; 5; 6; 7; 9; 10; 11; 12; 16; 19; 30; 31; 34; 36; 37; 39; 40; 42; 44; 51; 52; 53; 54; 56; 58; 59; 70; 71; 72; 73; 83; 84; 86; 88; 90; 92; 93; 95; 96; 100; 101; 102; 104; 106; 109; 110; 112; 117; 119; 124; 125; 127; 128; 131; 132; 133; 134; 135; 137; 158; 159; 160; 161; 162; 163; 165; 166; 167; 168; 170; 181; 182; 183; 189; 190; 192; 194; 196; 202; 210; 211; 212; 220; 225; 227; 228; 229; 230; 231; 233; 237; 238; 239; 240; 242; 246; 247; 248; 252; 259; 262; 264; SEQ ID NO：3的269。本发明还涉及编码变体的多核苷酸; 包含所述多核苷酸的核酸构建体，载体和宿主细胞; 以及使用这些变体的方法。

15. 发明公开

EP3950939A3 LIPASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME 审中-公开
公开(公告)号：EP3950939A3
公开(公告)日：2022-06-08
申请号：EP21177947.5
申请日：2016-07-06
申请人： Novozymes A/S
发明人： SAIKIA, Rakhi , MENDEZ, Geetha, Hiremath , DALAL, Sohel , BALUMURI, Padmavathi , MEPADAM, Santhosh, Vasu , BAUNSGAARD, Lone , VIND, Jesper , GIPPERT, Garry, Paul , BORCH, Kim
IPC分类号： C12N9/20 , C12N15/00 , C11D3/386
摘要： The present invention relates to a lipase variant of a parent lipase, which variant has lipase activity, at least 75% but less than 100% sequence identity to SEQ ID NO: 3 and comprises a substitution at one or more positions corresponding to positions 1; 2; 3; 4; 5; 6; 7; 9; 10; 11; 12; 13; 14; 15; 17; 18; 29; 30; 33; 34; 36; 37; 38; 40; 41; 43; 44; 45; 46; 47; 49; 50; 51; 52; 54; 55; 57; 58; 59; 60; 69; 70; 71; 72; 81; 82; 85; 86; 87; 89; 90; 91; 92; 94; 95; 96; 97; 99; 100; 101; 102; 103; 105; 108; 111; 115; 116; 118; 119; 120; 122; 123; 124; 126; 127; 128; 129; 130; 131; 132; 133; 134; 136; 144; 152; 155; 157; 158; 159; 161; 162; 163; 177; 178; 181; 182; 184; 185; 187; 189; 191; 196; 197; 199; 203; 205; 206; 207; 208; 209; 211; 215; 220; 221; 222; 223; 224; 226; 229; 230; 232; 235; 236; 240; 242; 243; 244; 247; 248; 252; 254; 255; 257; 260; 261; 262 of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

16. 发明公开

EP3052621A1 ALPHA-AMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME 审中-公开
标题翻译：阿尔法 - 氨基酸变体多巴酚丁胺
公开(公告)号：EP3052621A1
公开(公告)日：2016-08-10
申请号：EP14780450.4
申请日：2014-09-30
申请人： Novozymes A/S
发明人： ANDERSEN, Carsten , GHADIYARAM, Chakshusmathi , SAINATHAN, Rajendra, Kulothungan , BALUMURI, Padmavathi
IPC分类号： C12N9/28
CPC分类号： C12N9/2417 , C11D3/386 , C11D11/0017 , C12N9/96 , C12Y302/01001
摘要： The present invention relates to variants having alpha-amylaseactivity and polynucleotides encoding the variants. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the variants.
摘要翻译：本发明涉及具有α-淀粉酶活性的变体和编码变体的多核苷酸。本发明还涉及包含多核苷酸的核酸构建体，载体和宿主细胞以及生产和使用变体的方法。

17. 发明公开

EP3964575A3 ALPHA-AMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME 审中-公开
公开(公告)号：EP3964575A3
公开(公告)日：2022-09-28
申请号：EP21183499.9
申请日：2016-05-09
申请人： Novozymes A/S
发明人： ANDERSEN, Carsten , SRIVASTAVA, Vivek , BALUMURI, Padmavathi , CHAKRABARTI, Partha, Pratim , DALAL, Sohel
IPC分类号： C12N9/28
摘要： The present invention relates to alpha-amylase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

18. 发明公开

EP3320089A1 LIPASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME 有权
标题翻译：脂肪酶变体和编码相同的多核苷酸
公开(公告)号：EP3320089A1
公开(公告)日：2018-05-16
申请号：EP16736844.8
申请日：2016-07-06
申请人： Novozymes A/S
发明人： SAIKIA, Rakhi , MENDEZ, Geetha, Hiremath , DALAL, Sohel , BALUMURI, Padmavathi , MEPADAM, Santhosh, Vasu , BAUNSGAARD, Lone , VIND, Jesper , GIPPERT, Garry, Paul , BORCH, Kim
IPC分类号： C12N9/20 , C12N15/00 , C11D3/386
CPC分类号： C11D3/38627 , C11D3/38681 , C12N9/20
摘要： The present invention relates to a lipase variant of a parent lipase, which variant has lipase activity, at least 75% but less than 100% sequence identity to SEQ ID NO: 3 and comprises a substitution at one or more positions corresponding to positions 1; 2; 3; 4; 5; 6; 7; 9; 10; 11; 12; 13; 14; 15; 17; 18; 29; 30; 33; 34; 36; 37; 38; 40; 41; 43; 44; 45; 46; 47; 49; 50; 5 51; 52; 54; 55; 57; 58; 59; 60; 69; 70; 71; 72; 81; 82; 85; 86; 87; 89; 90; 91; 92; 94; 95; 96; 97; 99; 100; 101; 102; 103; 105; 108; 111; 115; 116; 118; 119; 120; 122; 123; 124; 126; 127; 128; 129; 130; 131; 132; 133; 134; 136; 144; 152; 155; 157; 158; 159; 161; 162; 163; 177; 178; 181; 182; 184; 185; 187; 189; 191; 196; 197; 199; 203; 205; 206; 207; 208; 209; 211; 215; 220; 221; 222; 223; 224; 226; 229; 230; 232; 235; 236; 240; 242; 243; 244; 247; 248; 252; 254; 255; 257; 10 260; 261; 262 of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

19. 发明公开

EP3964575A2 ALPHA-AMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME 审中-公开
公开(公告)号：EP3964575A2
公开(公告)日：2022-03-09
申请号：EP21183499.9
申请日：2016-05-09
申请人： Novozymes A/S
发明人： ANDERSEN, Carsten , SRIVASTAVA, Vivek , BALUMURI, Padmavathi , CHAKRABARTI, Partha, Pratim , DALAL, Sohel
IPC分类号： C12N9/28
摘要： The present invention relates to alpha-amylase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

20. 发明公开

EP3760713A2 LIPASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME 审中-公开
公开(公告)号：EP3760713A2
公开(公告)日：2021-01-06
申请号：EP20183586.5
申请日：2015-05-26
申请人： Novozymes A/S
发明人： BALUMURI, Padmavathi , SAIKIA, Rakhi , SVENDSEN, Allan , BAUNSGAARD, Lone
IPC分类号： C12N9/20 , C12P7/64 , C11D3/386
摘要： The present invention relates to a lipase variant of a parent lipase, which variant has lipase activity, at least 75% but less than 100% sequence identity to SEQ ID NO: 3 and comprises a substitution at one or more positions corresponding to positions 125; 1; 2; 3; 4; 5; 6; 7; 9; 10; 11; 12; 16; 19; 30; 31; 34; 36; 37; 39; 40; 42; 44; 51; 52; 53; 54; 56; 58; 59; 70; 71; 72; 73; 83; 84; 86; 88; 90; 92; 93; 95; 96; 100; 101; 102; 104; 106; 109; 110; 112; 117; 119; 124; 127; 128; 131; 132; 133; 134; 135; 137; 158; 159; 160; 161; 162; 163; 165; 166; 167; 168; 170; 181; 182; 183; 189; 190; 192; 194; 196; 202; 210; 211; 212; 220; 225; 227; 228; 229; 230; 231; 233; 237; 238; 239; 240; 242; 246; 247; 248; 252; 259; 262; 264; 269 of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

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