专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明申请

US20110222366A1 INJECTOR DEVICE 有权
标题翻译：注射器装置
公开(公告)号：US20110222366A1
公开(公告)日：2011-09-15
申请号：US13119258
申请日：2009-09-22
申请人： Niklas Axén , Hans Lennernäs , Johan Yngve , Lars Ake Malmsten , Gunilla Eketorp , Ake G. Pilbrant
发明人： Niklas Axén , Hans Lennernäs , Johan Yngve , Lars Ake Malmsten , Gunilla Eketorp , Ake G. Pilbrant
IPC分类号： B01F5/06
CPC分类号： A61M5/31596 , A61B17/8825 , A61B2017/8838 , A61M5/31511 , A61M5/31515 , A61M2005/31508 , B01F11/0082 , B01F13/002 , B01F13/0023 , B01F15/0279
摘要： An injector device is disclosed, the injector device comprising an elongated mixing container extending along a first axis, and a piston member slidably positioned in the mixing container. The injector device comprises a mixing device comprising a mixing member, an elongated member parallel to the first axis and a handle member. The piston member comprises a piston head and a first locking arm flexibly connected to the piston head, such that the first locking arm in a first position extends substantially parallel to the elongated member and engages with the mixing device in such a way that the piston member moves in a first direction along the first axis with the mixing device. In a second position, the first locking arm may allow the mixing device to move relative to the mixing container independently of the piston member.
摘要翻译：公开了一种注射器装置，所述注射器装置包括沿着第一轴线延伸的细长混合容器和可滑动地定位在所述混合容器中的活塞构件。注射器装置包括混合装置，其包括混合构件，平行于第一轴线的细长构件和手柄构件。活塞构件包括活塞头和柔性地连接到活塞头的第一锁定臂，使得第一位置处的第一锁定臂基本上平行于细长构件延伸并且与混合装置接合，使得活塞构件通过混合装置沿第一轴沿第一方向移动。在第二位置，第一锁定臂可允许混合装置独立于活塞构件相对于混合容器移动。

12. 发明授权

US08999389B2 Bioresorbable controlled-release composition 有权
标题翻译：生物可吸收的控释组合物
公开(公告)号：US08999389B2
公开(公告)日：2015-04-07
申请号：US12224942
申请日：2007-03-14
申请人： Hans Lennernäs , Niklas Axén
发明人： Hans Lennernäs , Niklas Axén
IPC分类号： A61K9/00 , A61K9/16
CPC分类号： A61K9/0024 , A61K9/0034 , A61K9/1611 , A61K9/1694
摘要： A novel method for the preparation of a highly densified and at least partly, preferably fully or almost fully hydrated ceramic for use in the preparation of a pharmaceutical composition notably for controlled-release of one or more therapeutically, prophylactically and/or diagnostically active substance. The method involves a concomitant step of hydrating and densifying a bioresorbable and hydratable ceramic such as calcium sulphate. The invention also relates to compositions comprising such a highly densified ceramic. The pharmaceutical composition is useful for targeted and controlled local prolonged release of active substances, e.g. anti-cancer agents, whereby the spectrum and severity of side effects are minimized due to an optimized local concentration-time profile.
摘要翻译：一种用于制备高致密化和至少部分，优选完全或几乎完全水合的陶瓷的新方法，用于制备药物组合物，特别是用于控制释放一种或多种治疗，预防和/或诊断活性物质。该方法包括水合和致密化生物可再吸收和可水合的陶瓷如硫酸钙的伴随步骤。本发明还涉及包含这种高密度陶瓷的组合物。药物组合物可用于靶向和受控局部延长的活性物质的释放，例如，由于优化的局部浓度 - 时间曲线，抗癌剂的副作用的频谱和严重程度被最小化。

13. 发明授权

US08936809B2 Method for treating prostate diseases based on local delivery of active substances 有权
标题翻译：基于活性物质的局部递送治疗前列腺疾病的方法
公开(公告)号：US08936809B2
公开(公告)日：2015-01-20
申请号：US11910162
申请日：2006-03-31
申请人： Hans Lennernäs , Bo Lennernäs , Jonas Hugosson , Niklas Axén
发明人： Hans Lennernäs , Bo Lennernäs , Jonas Hugosson , Niklas Axén
IPC分类号： A61K9/22 , A61K49/04 , A61K49/00 , A61K47/00 , A61K31/56 , A61K48/00 , A61K38/00 , A61K9/16
CPC分类号： A61K9/1647
摘要： A method for treating prostate related diseases in a subject, the method comprising i) optionally administering to subject an initial boost dose of one or more active substances and/or prodrugs, and ii) administering locally into the prostate a controlled release pharmaceutical composition comprising one or more active substances in a biodegradable ceramic carrier. The biodegradable hydrating ceramic may be selected from the group consisting of non-hydrated or hydrated calcium sulphate, calcium phosphate, calcium carbonate, calcium fluoride, calcium silicate, magnesium sulphate, magnesium phosphate, magnesium carbonate, magnesium fluoride, magnesium silicate, barium sulphate, barium phosphate, barium carbonate, barium fluoride, barium silicate, or mixtures thereof. In a specific embodiment, the biodegradable hydrating ceramic is non-hydrated or hydrated calcium sulphate.
摘要翻译：一种用于治疗受试者中前列腺相关疾病的方法，所述方法包括i）任选地施用受试者初始增强剂量的一种或多种活性物质和/或前药，以及ii）局部施用于前列腺中的控释药物组合物，其包含一种或更多的活性物质在可生物降解的陶瓷载体中。可生物降解的水合陶瓷可以选自非水合或水合硫酸钙，磷酸钙，碳酸钙，氟化钙，硅酸钙，硫酸镁，磷酸镁，碳酸镁，氟化镁，硅酸镁，硫酸钡，磷酸钡，碳酸钡，氟化钡，硅酸钡或其混合物。在一个具体实施方案中，可生物降解的水合陶瓷是非水合或水合硫酸钙。

14. 发明授权

US06541135B1 Seal rings with improved friction and wear properties 有权
标题翻译：密封圈具有改善的摩擦和磨损性能
公开(公告)号：US06541135B1
公开(公告)日：2003-04-01
申请号：US09678740
申请日：2000-10-04
申请人： Stefan Ederyd , Håkan Engqvist , Niklas Axén
发明人： Stefan Ederyd , Håkan Engqvist , Niklas Axén
IPC分类号： B32B900
CPC分类号： C23C30/005 , F16C33/043 , F16J15/3496 , Y10T428/265
摘要： The present invention relates to a cemented carbide wear part with a wear surface with improved friction and wear properties. This has been obtained by providing the wear surface with a surface layer with a thickness of 0.5 &mgr;m to 25 &mgr;m, preferably 1 to 10 &mgr;m with an average WC grain size of less than 500 nm. The surface layer is obtained by lapping the wear surface with an abrasive disc for at least 10 minutes at 1000 to 3000 rpm at a pressure of 0.1 to 0.5 MPa preferably without any grinding media.
摘要翻译：本发明涉及具有改善的摩擦和磨损性能的磨损表面的硬质合金耐磨部件。这是通过为磨损表面提供厚度为0.5μm至25μm，优选1至10μm的平均WC晶粒尺寸小于500nm的表面层而获得的。表面层是通过研磨盘研磨磨损表面至少10分钟，在1000至3000rpm，压力为0.1至0.5MPa，优选没有任何研磨介质的情况下获得的。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式