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    • 20. 发明申请
    • porous bioabsorbable material and method of producing the same
    • 多孔生物可吸收材料及其制造方法
    • US20090208586A1
    • 2009-08-20
    • US12293153
    • 2007-03-20
    • Toshinobu SajikiNaoyuki HanakiJunichi IdeFumiko Hirayama
    • Toshinobu SajikiNaoyuki HanakiJunichi IdeFumiko Hirayama
    • A61K9/16B29C67/20
    • A61L31/148A61L31/146C08J5/18C08J9/28C08J2201/048C08J2207/10C08J2300/14C08J2367/04
    • [Problems] To provide a thin film-shaped porous bioabsorbable material that is a dense structure in which the pore size average is small and the pore size is uniform and which further has a large maximum stress, in particular, a porous bioabsorbable material extremely useful as an adhesion preventing material.[Means for Solving Problems] A porous bioabsorbable material characterized by being formed of a porosified bioabsorbable polymer which is obtained in a manner that a bioabsorbable polymer is gelled with a good solvent and a poor solvent, compatible with each other, for the bioabsorbable polymer and the gelled bioabsorbable polymer is subjected to freeze-drying to be porosified; and a method of producing the porous bioabsorbable material, the method being characterized in that a bioabsorbable polymer is gelled with a mixed solvent composed of a good solvent and a poor solvent, compatible with each other, for the bioabsorbable polymer and the gelled bioabsorbable polymer is subjected to freeze-drying to be porosified.
    • [问题]提供一种致密结构的薄膜状多孔生物可吸收材料,其特征在于孔尺寸平均小,孔径均匀且进一步具有大的最大应力,特别是多孔生物可吸收材料非常有用 作为防粘连材料。 用于解决问题的方法一种多孔生物可吸收材料,其特征在于由可生物吸收性聚合物以可生物吸收性聚合物凝胶化的生物可吸收性聚合物形成的多孔生物可吸收性聚合物,该生物可吸收性聚合物与生物可吸收聚合物相互相容的良溶剂和不良溶剂凝胶化, 将凝胶状生物体吸收性聚合物进行冷冻干燥以进行孔化; 以及生产该多孔生物可吸收材料的方法,其特征在于,生物可吸收性聚合物由生物可吸收性聚合物相互相容的由良溶剂和不良溶剂组成的混合溶剂凝胶化,凝胶化生物可吸收聚合物为 进行冷冻干燥以进行孔化。