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    • 11. 发明申请
    • FEED ADDITIVES FOR RUMINANTS
    • 饲料添加剂
    • WO1998024329A1
    • 1998-06-11
    • PCT/JP1997004420
    • 1997-12-03
    • NIPPON SODA CO., LTD.MORIKAWA, TakaoSASAOKA, SeijiSAITO, ShigeruSUGAWARA, MasatoMUTO, KaoruYABUTA, Shigenori
    • NIPPON SODA CO., LTD.
    • A23K01/18
    • A23K50/10A23K40/35Y10S426/807
    • Lumen-bypass preparations for ruminants composed of a core preparation and a coating layer applied thereonto, characterized in that the core preparation contains from 50 to 90 % by weight, based on the core preparation, of a biologically active substance, that the active substance has been dispersed in from 10 to 50 % by weight of a protective substance, and that the coating layer applied onto the core preparation is made from at least one material selected among linear and branched, saturated and unsaturated aliphatic C12-24 monocarboxylates, polymers insoluble in the neutral region but soluble in the acidic region, and zein. Use of protective substances originating in natural substances and being harmless to the ecological system makes it possible to obtain lumen-bypass preparations which contain biologically active substances at a high concentration and are advantageous economically.
    • 用于由核心制剂和涂覆在其上的涂层组成的反刍动物的流明旁路制剂,其特征在于,核心制剂含有基于核心制剂的50-90重量%的生物活性物质,活性物质具有 分散在10〜50重量%的保护性物质中,涂布在核心制剂上的涂层由至少一种选自直链和支链,饱和和不饱和的脂族C 12-24单羧酸盐的材料制成,不溶于 中性区域但可溶于酸性区域,而玉米醇溶蛋白。 使用源自天然物质的保护性物质,对生态系统无害化,可以获得高浓度含有生物活性物质的管腔旁路制剂,经济有利。
    • 12. 发明申请
    • TRIAZINE DERIVATIVES AND RECORDING MATERIALS PREPARED THEREFROM
    • TRIAZINE衍生物和记录材料
    • WO1997016431A1
    • 1997-05-09
    • PCT/JP1996003176
    • 1996-10-30
    • NIPPON SODA CO., LTD.FUJII, HiroshiHIDAKA, TomoyaSATO, ShinichiAOKI, Izuo
    • NIPPON SODA CO., LTD.
    • C07D251/34
    • B41M5/3336B41M5/132B41M5/155B41M5/3375C07D251/26C07D251/34C07D251/38C07D251/46
    • Triazine derivatives of general formula (I); and recording materials excellent in the storage stability of developed images, particularly the resistance thereof to plasticizers [wherein R is hydrogen or alkyl; R1 and R2 are each hydroxyl, halogeno, alkyl or alkenyl; n and m are each an integer of 0 to 4; w is 0, 1 or 2; and Y and Z are each formula (a) (wherein R' is hydrogen or alkyl; R7 and R8 are each hydroxyl, halogeno, alkyl or alkenyl; u and v are each an integer of 0 to 4; w is 0, 1 or 2; and A is alkylene having an ether linkage), halogeno, hydroxyl, hydrogen, alkoxy, alkylthio or alkoxy having an ether linkage, alkylthio having an ether linkage, alkoxy having a thio ether linkage, alkylthio having a thio ether linkage, hydroxyalkoxy, hydroxyalkylthio, primary or secondary alkylamino, primary or secondary hydroxyalkylamino, aryloxy optionally substituted with hydroxyl, alkyl or halogeno, arylthio optionally substituted with hydroxyl, alkyl or halogeno, arylamino optionally substituted with hydroxyl, alkyl or halogeno, or aralkyloxy optionally substituted with hydroxyl, alkyl or halogeno].
    • 通式(I)的三嗪衍生物; 和显影图像的保存稳定性优异的记录材料,特别是其对增塑剂[其中R是氢或烷基; R1和R2各自为羟基,卤代,烷基或烯基; n和m各自为0〜4的整数; w为0,1或2; 并且Y和Z各自为式(a)(其中R'为氢或烷基; R 7和R 8各自为羟基,卤代,烷基或烯基; u和v各自为0至4的整数; w为0,1或 2; A是具有醚键的亚烷基),卤素,羟基,氢,烷氧基,烷硫基或具有醚键的烷氧基,具有醚键的烷硫基,具有硫醚键的烷氧基,具有硫醚键的烷硫基,羟烷氧基, 烷基或卤代,任选被羟基取代的芳氧基,烷基或卤代,任选被羟基取代的芳基氨基,烷基或卤代,或任选被羟基取代的芳烷基氧基,烷基或卤代 或卤代]。
    • 19. 发明申请
    • IMIDAZOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME
    • 咪唑衍生物及其制备方法
    • WO1995029163A1
    • 1995-11-02
    • PCT/JP1995000827
    • 1995-04-26
    • NIPPON SODA CO., LTD.MOCHIZUKI, NobuoUCHIDA, SeiichiKUMITA, IzumiMIYAMOTO, HiroyukiICHIHARA, Hiromi
    • NIPPON SODA CO., LTD.
    • C07D233/58
    • C07D231/12C07D233/56C07D249/08
    • A novel imidazole derivative represented by general formula (I) or a pharmaceutically acceptable salt thereof, useful as excellent antihyperlipemic and antiarteriosclerotic, wherein R represents hydrogen or lower alkyl; n represents 0 or 1; X represents N-r (r representing hydrogen or lower alkyl), O, S, SO, SO2, CH2, CH(CH3), CONH or C(r ) = NO (r representing hydrogen or lower alkyl); m represents an integer of 0.1 to 12; and A represents methyl or a group represented by general formula (2) wherein Y represents N-r (r representing hydrogen or lower alkyl), N(r )SO2 (r representing hydrogen or lower alkyl), O, S, SO, SO2, CH2, CH(CH3), CONH or C(r ) = NO(r representing hydrogen or lower alkyl); R represents halogen, lower alkyl, lower alkoxy, cycloalkyl or COOr (r representing hydrogen or lower alkyl); and 1 represents 0, 1, 2 or 3; provided that m represents an integer of 6 to 9 when A is methyl, that m represents an integer of 0, 1 to 6 when A is a group of general formula (2) and that X and Y represent each CH2 when m is 0.
    • 由通式(I)表示的新型咪唑衍生物或其药学上可接受的盐,可用作优异的抗高脂血症和抗动脉硬化,其中R 1表示氢或低级烷基; n表示0或1; X表示Nr 1(r 1表示氢或低级烷基),O,S,SO,SO 2,CH 2,CH(CH 3),CONH或C(r 2)= NO(r 2) 氢或低级烷基); m表示0.1〜12的整数, A表示甲基或由通式(2)表示的基团,其中Y表示Nr 3(r 3表示氢或低级烷基),N(R 4)SO 2(r 4表示氢或低级 烷基),O,S,SO,SO2,CH2,CH(CH3),CONH或C(r5)= NO(r5代表氢或低级烷基); R 2表示卤素,低级烷基,低级烷氧基,环烷基或COO 6(r 6代表氢或低级烷基); 和1表示0,1,2或3; 条件是当A为甲基时,m表示6至9的整数,当A为通式(2)的基团时,m表示0至1的整数,当m为0时,X和Y表示各自的CH 2。